U optužnici se Mladić, na osnovu pojedinačne i vrhovne komandne odgovornosti, optužuje po 13 tačaka zločina protiv čovječnosti i kršenja zakona ili običaja ratovanja, za djela progona, ubijanja, deportacije i nečovječnih postupaka, teroriziranja i uzimanja talaca, u kojima je navodno učestvovao.
The indictment charges Mladic, on the basis of his individual and superior criminal responsibility, with 13 counts of crimes against humanity and violations of the laws or customs of war for the acts of persecution, murder, deportation and inhumane acts, terrorising and hostage taking, in which he allegedly participated.