Plavšićeva je bila jedan od dva zamjenika bivšeg političkog lidera bosanskih Srba Radovana Karadžića tokom sukoba u BiH u periodu 1992-1995, tokom kog je poginulo oko 100.000 ljudi, a iz domova istjerano još njih preko 2 miliona.
Plavsic was one of former Bosnian Serb political leader Radovan Karadzic's two deputies during the 1992-1995 conflict in BiH, which left about 100,000 people dead and forced more than 2 million others to flee their homes.