U optužnici se Mladić, na osnovu svoje pojedinačne i komandne krivične odgovornosti, tereti po ukupno 13 tačaka zločina protiv čovječnosti i kršenja zakona ili običaja rata, za djela progona, ubijanja, deportacije i nehumanog postupanja, teroriziranja i uzimanja talaca, u kojima je on navodno učestvovao.
The indictment charges Mladic, on the basis of his individual and superior criminal responsibility, with a total of 13 counts of crimes against humanity and violations of the laws or customs of war, for the acts of persecution, murder, deportation and inhumane acts, terrorising and hostage-taking, in which he allegedly participated.