History of P53 - Li-Fraumeni syndrome. Evaluate for malignancy. Scattered very small lymph nodes are noted in the thorax abdomen and pelvis. In the aortopulmonary window there is a 1.7 x 1.6 cm well-circumscribed nodule (series 901/8). No pathologically enlarged lymphadenopathy. Bilateral probable adnexal follicles and cysts. The right ovary is enlarged measuring 5.2 x 4.0 cm with a 3.4 cm probable hemorrhagic cyst. Otherwise, no focal suspicious mass lesion is identified of the visceral organs.In the distal right femur involving the metaphyseal lateral cortex is a well-defined lobular lesion with a peripheral hypointense rim suggesting a peripherally sclerotic bone lesion, likely a benign fibrous cortical defect, however further confirmation with dedicated radiographs of the right femur is recommended. No additional focal lesion of the imaged osseous or soft tissue structures.
1. 1.7 cm nodule in the aortopulmonary window warrants further characterization with a dedicated chest CT. Differential diagnosis includes metastatic adenopathy, para ganglioma, or thymic origin neoplasm.2. Well-circumscribed lesion involving the lateral cortex of the distal right femoral metaphysis, likely a benign fibrous cortical defect, however confirmation with dedicated radiographs of the right femur is recommended. 3. Probable right adnexal hemorrhagic cyst. Follow-up pelvic ultrasound in 3 months to confirm resolution is recommended.4. Small scattered lymph nodes. 