Male, 59 years old, with disseminated histoplasmosis, Candida fungemia, evaluate for fungal/histo focus in the brain. Encephalomalacia and signal abnormality suggesting gliosis are seen at the junction of the right inferior parietal lobe and temporal lobe. A small but similar-appearing lesion is also seen in the left frontal lobe. No evidence of restricted diffusion is seen. No edema or mass effect is detected. A few punctate scattered foci of T2 hyperintensity are nonspecific. Prominence of the CSF spaces is suggestive of underlying parenchymal volume loss. Prominent prevascular spaces are seen in the left basal ganglia.Asymmetry of the ventricles is likely congenital. The size of the ventricles remains within normal limits. There may be a small ependymal cyst at the left atrium. No evidence of intracranial hemorrhage or any abnormal extra-axial fluid collection is seen.
1.No findings are seen to suggest active intracranial infection. No acute abnormalities are evident.2.Encephalomalacia and gliosis of the right inferior parietal lobe may reflect prior ischemia. A smaller lesion in the left frontal lobe is also possible ischemic in nature.