33 year old with proven left breast cancer presents for I-SPY 2 study #1. There is extreme amount of fibroglandular tissue in both breasts.Moderate parenchymal enhancement is noted bilaterally.The left breast shows diffuse abnormal enhancement, measuring 65 x 97 x 126 mm (AP x LR x CC), consistent with biopsy proven carcinoma. Diffuse edema is present. A Hydromark clip is identified at anterior 12 o'clock position in the left breast.There one abnormal lymph node showing cortical thickening, measuring 26 mm in maximum diameter, in the left axilla. This lymph node shows a high T2 signal marker, consistent with proven metastatic lymph node. Multiple small cysts are present in the right breast.No abnormal enhancement is seen in right breast. No abnormal axillary lymph nodes are identified in right axillary region.
1. Diffuse enhancement in the left breast, consistent with proven cancer, with a metastatic left axillary lymph node2. No MR evidence of malignancy in the right breast.BIRADS: 6 - Known cancer.RECOMMENDATION: X - No Letter.