Female, 18 months old, with seizures x2 (staring episodes). The septum pellucidum is absent with associated findings of flattening of the roof of the frontal horns and draping of the floor of the frontal horns around the forniceal columns. The corpus callosum is fully formed and intact. The posterior body may be slightly thinned but this can also be a normal variation for age. The fornices are present and within normal limits.The anterior pituitary gland demonstrates normal size and morphology. The posterior pituitary gland is normally positioned within the posterior aspect of the sella and is also within normal limits. The pituitary stalk is present and seems to be of normal caliber.The optic chiasm is present and probably within normal limits for size. The right optic nerve, however, appears to be slightly smaller than the left. The shape the globes is within normal limits.A small parenchymal defect is present along the right caudothalamic groove. No evidence of any cerebral clefting is seen. No definite ectopic cortex, cortical dysplasia or migrational anomaly is seen.No evidence of acute intracranial hemorrhage is seen. There are no abnormal extra-axial fluid collections.The degree of sulcation appears to be normal for age. The pattern of white matter myelination is appropriate for age. Mild T2 hyperintensity along the lateral ventricular atrium may represent the so-called terminal zones of myelination.
1.Constellation of findings including absence of the septum pellucidum, anomalous shape of the frontal horns, and questionable mild hypoplasia of the right optic nerve highly suggestive of septo-optic dysplasia.2.The corpus callosum and fornices are visualized and intact. No evidence of schizencephaly or any definite cortical heterotopia, dysplasia or migrational anomaly is seen.3.A small parenchymal defect is evident along the right caudothalamic groove. This could reflect the sequela of a remote, potentially prenatal or perinatal insult.