Motor neuron disease, unspecified [G12.20], Reason for Study: ^Reason: Any intracranial lesion? Also do 3T CCD MRI Javed MS protocol with DTI History: Weakness of UEs with hyperreflexia There are multifocal scattered T2/FLAIR high signal intensity lesions on bilateral periventricular white matter, centrum semiovale, subcortical white matter and pons. In addition, T2/FLAIR high signal intensity lesions also seen on bilateral basal ganglia.These lesions are nonspecific, however, at this age, nonspecific small vessel ischemic disease is a possibility in addition to demyelinating disease. Clinical correlation is recommended.The ventricles, sulci and cisterns are unremarkable. There is no mass, mass effect, edema, midline shift, intra or extra-axial fluid collection. Normal flow voids are identified in the major intracranial vessels. The paranasal sinuses and mastoid air cells are clear.
Multifocal nonspecific bihemispheric T2/FLAIR high signal intensity lesions. Differential diagnosis include nonspecific small vessel ischemic disease and demyelinating disease.