Post resection of GBM with Ziopharm trial. Evaluate changes in tumor. Postoperative changes are redemonstrated within the left temporal lobe, with hemosiderin deposition in the resection bed. There is abnormal enhancing tissue along the operative margin, which is decreased in size compared to prior, measuring 2.9 x 1.4 cm, previously 4.1 x 1.8 cm. There is also decreased ependymal enhancement along the atrium of the left lateral ventricle. The ventricles are unchanged in size. T2 hyperintensity involving the left temporal, parietal and occipital lobes is decreased from prior. No new enhancing lesions are identified. There are scattered foci of FLAIR T2 hyperintensity within the subcortical and periventricular white matter, which are nonspecific and not significantly changed. Evidence of endoscopic paranasal surgery is redemonstrated, with persistent ethmoid and frontal mucosal thickening.
Decreased size of enhancing tissue along the left temporal operative margin, and decreased associated T2 FLAIR hyperintensity. Ependymal enhancement involving the atrium of the left lateral ventricle is also decreased. No new lesion is identified.