35-year-old male with right-sided weakness, history of potential multiple sclerosis Redemonstrated are numerous T2 hyperintense lesions within the supratentorial and infratentorial brain, many of which demonstrate an ovoid shape, are perpendicular to the callosal-septal interface, and are confluent in several locations. Several lesions with low T1 signal are again noted. Unlike previously, none demonstrate enhancement, and there are no definite new discrete lesions. No evidence of acute ischemia or hemorrhage. No intracranial mass or mass effect. No hydrocephalus. No extra-axial collections. There is volume loss, particularly involving the corpus callosum. Major flow-voids are preserved. Sella and orbits are grossly within normal limits. Mucous retention cysts are again seen within the maxillary sinuses. Paranasal sinuses and mastoid cells are otherwise clear.
Redemonstrated are numerous T2 hyperintense lesions within the supratentorial and infratentorial brain, many of which demonstrate an ovoid shape, are perpendicular to the callosal-septal interface, and are confluent in several locations. Several lesions with low T1 signal are again noted. Unlike previously, none demonstrate enhancement, and there are no definite new discrete lesions. The constellation of these features are suggestive of demyelination (e.g. multiple sclerosis) in the correct clinical context.