45 years, Female, paresthesias. Multiple sclerosis, follow-up progression. There is extensive confluent T2/FLAIR hyperintensity throughout the bilateral supratentorial subcortical and periventricular white matter compatible advanced chronic demyelinating disease. There is advanced global parenchymal volume loss including diffuse thinning of the corpus callosum. Compared to prior study from 3/15/2011, no significant change is appreciated. Minimal signal abnormality is evident in the brainstem and cerebellum and more evident on remote MRI study from 6/19/2008.No evidence of intracranial mass effect, midline shift, or herniation. No hydrocephalus. No extra-axial collections. Calvarium and extra cranial soft tissues are grossly unremarkable.
Extensive white matter signal abnormality throughout the bilateral cerebral hemispheres compatible with advanced chronic demyelinating disease. Extensive parenchymal volume loss is also evident. These findings are not appreciably changed since 3/15/2011.