Tuberous sclerosis [Q85.1], Reason for Study: ^Reason: Evaluate for SEGA and SET History: 5 yo with tuberous sclerosis There are multifocal bihemispheric T2/FLAIR high signal intensity lesions involving cortical, subcortical gray matter and periventricular white matter indicating tuberous sclerosis related cortical tubers. The number, size and MR characteristics including non-enhancing nature do not show any significant interval change since prior scan.There are multiple variable sized enhancing nodules following ependymal lining with most of them demonstrate susceptibility artifacts indicating possible internal mineralization. Those lesions are measured from submillimeter to about 10mm which the largest one at the left lateral ventricle. Comparing to prior scan, those lesions do not show any interval changes in terms of number and maximum diameter. There is no evidence of acute ischemic or hemorrhagic lesion.The ventricles, sulci and cisterns are symmetric and unremarkable. The midline structures and cranial-cervical junction are normal. Normal flow voids are identified in the major intracranial vessels. The paranasal sinuses and mastoid air cells are clear.
1. Multifocal cortical, subcortical and white matter T2/FLAIR high signal intensity lesions without evidence of enhancement consisted with cortical/subcortical tubers, unchanged since prior scan.2. Multiple bilateral ependymal nodular lesions with most of them enhancing and some show susceptibility artifacts without evidence of interval enlargement in maximum diameter.3. No evidence of acute ischemic or hemorrhagic lesion.