NSCLC brain metastases with progression after WBRT, now on PD1 Ab. There are multiple, at least 25, generally subcentimeter supratentorial and infratentorial cortical and juxtacortical enhancing lesions. Although the enhancing lesions appear to be generally similar in size and number, comparison with the prior study is limited due to the differences in slice thickness. However, there has been markedly decreased vasogenic edema associated with many of the lesions. There is no evidence of intracranial hemorrhage, mass, or acute infarct. The brain parenchyma and pituitary gland appear unremarkable. There is no abnormal intracranial enhancement. The ventricles and basal cisterns are normal in size and configuration. There is no midline shift or herniation. The major cerebral flow voids are intact. The orbits, skull, paranasal sinuses, and scalp soft tissues are grossly unremarkable.
Multiple, at least 25, generally subcentimeter supratentorial and infratentorial intracranial metastases. Although the enhancing lesions appear to be generally similar in size and number, comparison with the prior study is limited due to the differences in slice thickness. However, there has been markedly decreased vasogenic edema associated with many of the lesions, which is likely attributable to treatment effects. 