Langerhans cell histiocytosis with new onset polydipsia and polyuria; assess for pituitary involvement. Pituitary: The T1 hyperintense posterior pituitary bright spot is no longer evident. There is also new mild thickening of the pituitary infundibulum. Otherwise, there is no evidence of sellar tumors. The optic apparatus and cavernous sinuses are intact. Brain: There is no evidence of intracranial hemorrhage, mass, or acute infarct. The brain parenchyma is unremarkable and there is no abnormal intraparenchymal enhancement. The ventricles and basal cisterns are normal in size and configuration. There is no midline shift or herniation. The major cerebral flow voids are intact. The orbits, skull, paranasal sinuses, and scalp soft tissues are grossly unremarkable. In particular, there is no evidence of recurrent temporal bone lesion.
1. Mild thickening of the pituitary infundibulum and loss of the posterior pituitary bright spot suggests incipient Langerhans cell histiocytosis of the hypothalamic-pituitary axis. 2. No evidence of recurrent temporal bone region Langerhans cell histiocytosis.