Female, 24 years old, with history of melanoma and a left-sided brain lesion. fMRI is requested for surgical planning purposes. All tested language paradigms produced reliable language related cortical activation. Language is left dominant. Broca's area activity is seen as expected within the left inferior frontal gyrus (primarily the pars triangularis and pars opercularis). Wernicke's area activity is seen as expected along the posterior aspect of the left superior temporal gyrus and sulcus. Both Broca's and Wernicke's areas are well removed from the patient's left middle frontal gyrus lesion. Of note, however, there is evidence of secondary language related activity located anterior, medial and superior to the lesion.
Successful fMRI for pre-surgical language mapping. Language is left dominant. Broca's and Wernicke's areas are well removed from the left middle frontal gyrus lesion. Evidence of secondary language related activity is seen in the vicinity of the lesion, as above. 