Female, 24 years old, with anaplastic astrocytoma currently on Avastin. Postoperative findings are again seen compatible with left parietal craniotomy and prior tumor resection. The resection cavity and several smaller cystic spaces anterior to the main cavity show no significant interval change.Small foci of enhancement within the parenchyma anterior to the resection cavity are slightly more conspicuous when compared to the immediate prior examination. These small foci track anteriorly along the left temporal horn. However, these foci remain significantly reduced when compared to the examination of 07/11/16. T2 FLAIR hyperintensity surrounding the resection cavity has not significantly changed.However, thickening of the splenium of the corpus callosum has progressed from the prior examination. This tissue does not enhance, though it does demonstrate marked diffusion restriction which is also progressed from prior.Ill-defined periventricular FLAIR hyperintensity is unchanged. Minimal FLAIR hyperintensity in the pons along with a probable cavernous malformation are unchanged. Ventricular size morphology are stable as well. Mucosal thickening is unchanged in the right maxillary sinus.
1.Relatively stable appearance of the left parietal resection cavity and adjacent tissues. There are small foci of enhancement in this area and tracking along the left temporal horn which are slightly more conspicuous than on the immediate prior examination, though they remain significantly improved relative to the examination of 07/11/16.2.However, progressive thickening of the splenium of corpus callosum is seen. This tissue does not enhance but demonstrates marked diffusion restriction. This finding is concerning for progression of nonenhancing tumor in the context of antiangiogenic therapy.