52 year old female with history of metastatic breast cancer and HIV status post seizure; evaluate. There is no evidence of intracranial hemorrhage. The ventricles and basal cisterns are mildly increased in volume; unchanged. Patchy areas of hypoattenuation are seen in the subcortical white matter (image 22 of 36, series #6747). Increased soft tissue density seen just posterior to the right globe and within the intraconal space; see recent brain MRI for further discussion. The calvaria and skull base are radiographically normal. The visualized paranasal sinuses and mastoid air cells are normally pneumatized.
1. Patchy areas of hypoattenuation in subcortical white matter may represent progressive multifocal leukoencephalopathy versus primary HIV infection.  2. Increased soft tissue density noted just posterior to the right globe and within the intraconal space. Please see brain MRI report from 11/16/2008 for further evaluation.