Clinical question: Metastatic breast cancer, baseline prior to starting on clinical trial. Signs and symptoms: No clinical signs of brain metastases. Pre-and post enhanced brain MRI:Negative diffusion weighted images.Examination demonstrate normal anatomical morphology and signal intensity to brain parenchyma on all MRI sequences. Unremarkable cerebral cortex, cortical sulci, ventricular system, CSF spaces and brain myelination.No detectable abnormal parenchymal or leptomeningeal enhancement.Normal signal intensity calvarial gland without detectable abnormal enhancement.Unremarkable images through the orbits and including axial fat sat post enhanced series.Normal signal intensity of paranasal sinuses and bilateral mastoid air cells and middle ear cavities.
Negative pre-and post enhanced brain MRI. 