Reason: THis is a 26 y/o male with sickle cell disease with h/o iron deposition from multiple transfusions. Referred for cardiovascular MRI to evaluate for iron deposition on cardiac muscle Left VentricleThe left ventricle is severely enlarged with normal systolic function. The overall LV ejection fraction is 58%, the LV end diastolic volume index is 140 ml/m2 (normal range: 74+/-15), the LVEDV is 267 ml (normal range 142+/-34), the LV end systolic volume index is 59 ml/m2 (normal range 25+/-9), the LVESV is 112 ml (normal range 47+/-19), the LV mass index is 98 g/m2 (normal range 85+/-15), and the LV mass is 187 g (normal range 164+/-36). There are no regional wall motion abnormalities present. There is no late gadolinium enhancement to suggest the presence of an underlying fibrosing, infiltrative, or inflammatory process. Left AtriumThe left atrium is moderate enlarged. Right VentricleThe right ventricle is moderately enlarged with normal systolic function. The overall RV ejection fraction is 57%, the RV end diastolic volume index is 135 ml/m2 (normal range 82+/-16), the RVEDV is 258 ml (normal range 142+/-31), the RV end systolic volume index is 58 ml/m2 (normal range 31+/-9), and the RVESV is 111 ml (normal range 54+/-17).Right AtriumThe right atrium is moderately enlarged.Aortic ValveThe aortic valve opens widely and there is no significant aortic regurgitation.Mitral ValveThe mitral valve opens widely and there is no significant mitral regurgitation. Mitral valve leaflets are mildly thickened.Pulmonic ValveThe pulmonic valve opens widely. There is no significant pulmonic regurgitation.Tricuspid ValveThe tricuspid valve opens widely. There is no significant tricuspid regurgitation.AortaThere is a left sided aortic arch with a normal branching pattern. The aortic root is normal in size.Pulmonary VeinsAll four pulmonary veins drain normally into the left atrium.Pulmonary ArteryThe main pulmonary artery is normal in size.Venous AnatomyThe SVC and IVC drain normally into the right atrium.PericardiumThere is a small pericardial effusion.Extracardiac FindingsThere are trace bilateral pleural effusions. There is severe iron overload in the liver based on T2* imaging. Small pleural effusions.
1. Severely dilated left ventricle with normal systolic function (LVEF 58%). There is no evidence of iron overload in the myocardium. There is no late gadolinium enhancement to suggest the presence of an underlying fibrosing, infiltrative, or inflammatory process2. Moderately dilated right ventricle with normal systolic function (RVEF 57%)3. Severe iron overload in the liver.4. Moderately dilated right and left atria.5. Small pericardial effusion and trace bilateral pleural effusions.I personally reviewed the Images and/or procedure with the Resident/Fellow and agree with this report.