47-year-old woman with IDC grade 3 with lobular features and DCIS grade 3, and a metastatic right axillary lymph node presents for I-SPY research MRI (#2). There is scattered fibroglandular tissue in both breasts.Mild parenchymal enhancement is noted bilaterally.RIGHT BREAST:A lobulated mass at anterior 12:00 position, which is a known carcinoma, measures 42 x 37 x 39 mm (AP x LR x CC, previously 49 x 48 x 62 mm). Periareolar skin thickening is mildly reduced. Multiple benign masses are unchanged. Anterior lateral aspect of right breast is locally depressed by a pressure dressing from a research biopsy performed yesterday.A proven metastatic right axillary lymph node measures 25 x 17 mm (previously 33 x 23 mm). A marker clip is present within the lymph node. LEFT BREAST:No abnormal enhancement is seen in left breast. Susceptibility artifact from a port is again present in the left medial chest wall.
Reduction in size of the known cancer in the right breast and the metastatic right axillary lymph node.BIRADS: 6 - Known cancer.RECOMMENDATION: X - No Letter.