55-year-old female with known IDC in the left breast on chemotherapy presents for I-SPY 2 research MRI #3. There is heterogeneous amount of fibroglandular tissue in both breasts.Mild parenchymal enhancement is noted bilaterally.RIGHT BREAST:The index mass currently measures 11 x 10 x 10 mm (previously 15 x 16 x 14 mm).Anterior satellite mass is not visualized. A small enhancing focus (5mm) located medially and superiorly to the index mass remains. Small enhancing masses medial to the index mass are no longer visualized along the pectoralis muscle. Areas of chest wall enhancement are not seen. The non-mass enhancement due to biopsy becomes less enhancing.LEFT BREAST:No abnormal enhancement is seen in the left breast. AXILLAE:No abnormal axillary lymph nodes are identified in either axillary region.OTHERS:Scattered high T2 liver lesions are not significantly changed.
1. Interval decrease of index cancer in the right breast.2. Additional enhancing lesions in the right breast and chest wall are no longer visualized, except for the enhancing focus located medially and superiorly to the index mass.BIRADS: 6 - Known cancer.RECOMMENDATION: X - No Letter.