22 agenesis of the corpus callosum. Assess for septo-optic dysplasia. BRAIN:There is complete agenesis of the corpus callosum with the associated lateral ventricular colpocephaly and parallel orientation. The septum pellucidum is absent. There is no interhemispheric cyst or lipoma. There is a persistent falcine sinus. There is crowding in the posterior fossa which likely relates to low position of the tentorium cerebelli and perhaps also a rather large cerebellum. Despite the crowding, there is no significant downward extension of the cerebellar tonsils through foramen magnum. Otherwise, there is no focal brain abnormality. Myelination is appropriate for age. Major intracranial vascular flow voids are preserved.The extra-axial/subarachnoid spaces, especially bifrontally, are prominent but maintain normal CSF signal. Given given the provided history of large head, this likely represents benign expansion of the extra-axial spaces of infancy. Prominent adenoids and included upper cervical lymph nodes are nonspecific in this age group. There is also nonspecific mucosal thickening/fluid signal in the ethmoid sinuses and right mastoid air cells.PITUITARY:The posterior pituitary bright spot is preserved. The optic infundibulum is midline and not thickened. There is no gross pituitary abnormality but the study was performed without intravenous contrast.ORBITS:There is suggestion of the left optic nerve being very minimally smaller and more T2-hyperintense than the right. The remainder of the optic apparatus is unremarkable. There is no orbital abnormality. Olfactory nerves are present bilaterally.
1.Complete agenesis of corpus callosum with associated findings. 2.There is suggestion of very minimal asymmetry between the optic nerves, the left being smaller. Optic nerve atrophy, however, is probably better assessed clinically. There is no significant abnormality along the optic apparatus or in the orbits otherwise.3.The posterior pituitary bright spot is preserved and the pituitary gland is otherwise unremarkable.4.Bifrontal prominent extra-axial fluid is compatible with benign expansion of the extra-axial spaces of infancy, which is most commonly a self-limiting process resolving by the age of 2 years.5.Posterior fossa crowning is probably related to a low lying tentorium and perhaps also a prominent cerebellum. 