Clinical question: Evaluate for lesion. Signs and symptoms: Neuropathy. Pre and post enhanced brain MRI:Negative diffusion weighted series.There is no evidence of congenital anatomical anomaly of the brain.There is also normal signal intensity of brain parenchyma on all MRI sequences.There is however prominence of bilateral hemispheric cortical sulci and cerebellar-vermian folia as well as mild to moderately enlarged ventricular system for patient's stated age of 28 concerning for underlying parenchymal volume loss.Anatomical variation of midline cisterna magna is detected.Post enhanced images demonstrate no detectable abnormal parenchymal or leptomeningeal enhancement.Calvarium demonstrate normal signal intensity and without abnormal enhancement.The signal void of major intracranial arterial branches are identified.The signal intensity of intracranial venous sinuses is within normal and with normal pattern of enhancement.Unremarkable images through the orbits and including axial fat sat post enhanced series.Paranasal sinuses and bilateral mastoid air cells and middle ear cavities demonstrate normal pneumatization signal pattern.
1.Examination demonstrates generalized prominence of cortical sulci, ventricular system and mildly of the cerebellar/vermis folia for patient's stated age of 28 and concerning for underlying parenchymal volume loss.2.There is however no detectable signal abnormality of the brain on any of the MRI sequences and no detectable abnormal enhancement.3.Unremarkable calvarium, orbits, paranasal sinuses and mastoid air cells.