36 year old with known right breast cancer and metastatic right axillary lymph node presents for research MRI of I-SPY protocol (2nd time point). There is heterogeneous amount of fibroglandular tissue in both breasts.Marked parenchymal enhancement is noted bilaterally.A known cancer is again identified at posterior 11 o'clock position, measuring 18 x 16 x 19 mm (AP x LR x CC, previous measurement: 24 x 26 x 23 mm). There is a linear non mass enhancement extending inferior and anterior from the known cancer measures 31 x 6 x 8 mm (previously 50 x 22 x 25 mm), and the overall size of the mass with non mass enhancement is 31 x 6 x 25 mm (previously 50 x 22 x 45 mm). An enlarges lymph node is again seen in the right axilla, with maximum diameter of 15 mm (previously 17 mm). No abnormal enhancement is seen in left breast. No abnormal axillary lymph nodes are identified in left axillary region.
Mild decrease in size of known cancer in the right breast and metastatic right axillary lymph node.BIRADS: 6 - Known cancer.RECOMMENDATION: X - No Letter.