H/o AML. S/p intrathecal methotrexate. There is a redemonstration of bilateral hemispheric subcortical and white matter edema. In comparison with prior brain MRI, the extent of the edema has been grossly unchanged. A right frontal Omaya catheter is in place with its tip in the left lateral ventricle. Air is present in bilateral frontal horns. There is no intracranial hemorrhage, mass, midline shift or abnormal extraaxial fluid collection. The ventricles are normal in volume and are symmetric. The visualized paranasal sinuses and mastoid air cells are normally pneumatized.
Grossly stable subcortical and white matter edema likely represent drug related change in light of clinical history provided. 