Male, 56 years old, with anaplastic astrocytoma, status post re-RT, now on TMZ/Avastin. No significant interval change is seen in the previously biopsied, treated tumor centered on the left thalamus. As before, this tissue is intrinsically T1 hyperintense with no clear superimposed enhancement.The centrally necrotic, faintly rim-enhancing lesion within the right posterior paramedian frontal lobe is for the most part stable to slightly smaller than on the prior examination. However, this lesion does infiltrate into the underlying corpus callosum, and the callosal component of the lesion has become progressively thicker.Areas of mild tumoral thickening within the left insula, along the left ventricular atrium, and in the left posterior temporal cortex, with associated ill-defined and ribbonlike enhancement, are not appreciably changed.No new enhancing lesions are identified. Ill-defined T2 hyperintensity in the left periventricular white matter is unchanged. No evidence of significant generalized mass effect is seen. Ventricles are stable in size and morphology.
1.Although the centrally necrotic tumor component within the right posterior paramedian frontal lobe is largely unchanged in size, there is progressive extension of tumor from this lesion into the underlying corpus callosum.2.Other areas of tumor remain stable, and no entirely new lesions are detected.