Clinical question: 60 year-old female with metastatic NSCLC. Signs and symptoms: Disease progression in bone, restaging. Pre-and post-enhanced brain MRI:Negative diffusion weighted series.Examination demonstrates normal anatomical morphology as well as signal intensity of brain parenchyma on all MRI sequences.Unremarkable cerebral cortex, cortical sulci, ventricular system, CSF spaces and brain myelination.Post enhanced images demonstrate no abnormal enhancement of brain parenchyma or the leptomeninges to suggest metastatic disease.Calvarium and soft tissues of the scalp demonstrate normal signal intensity and without detectable abnormal enhancement.Negative images through the orbits and including axial fat sat post enhanced series.Normal pneumatization signal pattern of all paranasal sinuses and bilateral mastoid air cells and middle ear cavities. Mild mucosal thickening of left maxillary sinus however is noted.
1.Negative pre-and post enhanced brain MRI.2.Mild left maxillary sinus disease.