Male, 70 years old, with GBM, on Avastin and CCNU. A heterogeneous mass with thick rim enhancement centered on the left parietal lobe and ventricular atrium has not significantly changed in size on the noncontrast images. As before, this lesion infiltrates the splenium of the corpus callosum extending to the contralateral side. Likewise, the morphology and thickness of enhancing tissue along the lesion margin has not significantly changed. As before, thin enhancement extends from the lesion along the ependymal surface of the left temporal horn.Within the limitations of motion degraded sequences, no additional or new enhancing lesions are seen. The previously noted leptomeningeal enhancement along the brainstem and cerebellum is not discretely identified on today's study.The degree of T2 signal abnormality surrounding the left parietal lesion has not significantly changed, nor has associated regional mass effect. The left ventricular atrium remains completely effaced but the ventricular size and morphology are unchanged.Patchy ill-defined T2 hyperintensity within the white matter elsewhere in the cerebral hemispheres is not changed from prior. No abnormal fluid collections are seen.
No significant interval change in size is seen of a thick rim enhancing tumor in the left parietal lobe. As before, spread of disease is seen along the ependymal surface of the left temporal horn. Leptomeningeal disease seen previously along the brainstem and cerebellum is no longer readily apparent.