Female, 55 years old, with history of seizures and MS, on Tecfidera, with EEG findings localized to the left frontal lobe. Confluent periventricular T2 hyperintensity is seen with additional scattered foci affecting the basal ganglia, brainstem and posterior fossa. On comparison with the prior MRI examination from 2008, these findings have progressed slightly. No dominant or discrete lesions are seen in the left frontal lobe to account for EEG findings.No restricted diffusion, edema or mass effect is detected. No pathologic intracranial enhancement is observed. There is no evidence of intracranial hemorrhage or any abnormal extra-axial fluid collection. Generalized parenchymal volume loss is demonstrated slightly progressed from prior. The ventricular system is unremarkable.
Extensive confluent patchy T2 hyperintense signal is seen within the cerebral hemispheres, brainstem and cerebellum compatible with the stated history of multiple sclerosis. These findings have progressed mildly from the prior examination. No dominant or discrete lesion is seen in the left frontal lobe to account for EEG findings.