65 years, Male, history of small cell lung cancer. Extensive confluent T2/FLAIR hyperintensity is seen in the bilateral subcortical and periventricular white matter, which is nonspecific, but may reflect post-treatment related leukoencephalopathy and/or chronic small vessel ischemic disease. No restricted diffusion to suggest acute ischemia. No intracranial mass or mass-effect. The ventricles are within normal limits in size and configuration. No abnormal parenchymal or meningeal enhancement. Major flow-voids are preserved.Sella and orbits are grossly within normal limits. Paranasal sinuses and mastoid cells are clear. There is T1 shortening in the calvarium, particularly at the skull base, which may reflect sequela of prior radiation treatment. No destructive osseous lesions.
1. No evidence of intracranial metastatic disease.2. Extensive white matter signal abnormality which may represent post-treatment related leukoencephalopathy or chronic small vessel ischemic disease.