Female, 73 years old, with memory loss. Amaranth study subject, Alzheimer's disease clinical trial. Image quality is slightly limited by motion artifact. Moderately extensive scattered periventricular foci of FLAIR hyperintensity are seen. No restricted diffusion is seen. No edema or mass effect is detected. No evidence of intracranial hemorrhage or any abnormal extra-axial fluid collection is seen. Ventricular size and morphology are within normal limits. Brain parenchymal volume is relatively well preserved. Diffuse paranasal sinus mucosal thickening is seen. In particular, the maxillary sinuses are completely opacified and there is polypoid-like mucosal protrusion through the left ostiomeatal unit.
1.Scattered foci of periventricular FLAIR hyperintensity are nonspecific but statistically most likely represent chronic microvascular ischemia.2.Brain parenchymal volume is relatively well-preserved.3.Extensive paranasal sinus mucosal thickening.