CNS lymphoma; restaging scan following chemotherapy. There are left transfrontal post-biopsy findings, including intrinsic T1 hyperintensity and susceptibility effect related to chronic blood products. There are also patchy areas of enhancement in the left frontal lobe periventricular white matter region, posterior left corpus callosum, as well as in the left basal ganglia. There are also numerous scattered nonspecific punctate foci of T2 hyperintensity in the cerebral white matter. There is no evidence of acute intracranial hemorrhage or acute infarct. There is diffuse cerebral volume loss. There is no midline shift or herniation. The major cerebral flow voids are intact. Artifacts related to dental implants obscures portions of the face.
1. Periventricular areas of enhancement in the left frontal lobe and posterior corpus callosum, as well as in the left basal ganglia, are compatible with central nervous system lymphoma superimposed upon prior left transfrontal post-biopsy effects. 2. Numerous scattered nonspecific punctate foci of T2 hyperintensity in the cerebral white matter may represent chronic small vessel ischemic disease, for example.