90-year-old female with history of headache. Corpus callosum lesion identified on prior MRI. 1 year follow-up. Again seen there is T2 hyperintensity affecting the inferior portion of the splenium as well as the undersurface of the posterior body of the corpus callosum and posterior fornices. This is not associated with any mass effect or enhancement. There is no associated restricted diffusion. There is no significant interval change dating back to 9/13/2013. Perfusion imaging demonstrates no evidence of increased relative cerebral blood volume.Additional scattered foci of T2 hyperintensity in the periventricular and subcortical white matter compatible with chronic small vessel ischemic changes are not significant change from prior. No evidence of intracranial hemorrhage, mass, or abnormal enhancement. The ventricles remain within normal limits for size and shape. The visualized paranasal sinuses are clear. There is partial opacification of the mastoid air cells bilaterally.
Stable appearance of the increased T2 signal centered within the splenium of the corpus callosum. Again there is no mass effect or abnormal enhancement to suggest a neoplastic process. The differential remains chronic sequela of vascular, metabolic, or toxic processes in addition to demyelinating disease or post infectious/inflammatory etiologies.