47-year-old woman with IDC grade 3 with lobular features and DCIS grade 3, and metastatic right axillary lymph node, presents for I-SPY research MRI (#1). There is scattered fibroglandular tissue in both breasts.Mild parenchymal enhancement is noted bilaterally.RIGHT BREAST:There is a heterogeneous lobulated mass, measuring 49 x 48 x 62 mm (AP x LR x CC), at anterior 12:00 position, consistent with a biopsy proven carcinoma. There is associated nipple retraction and periareolar skin thickening. There are multiple benign masses (three in the lateral breast and one in the medial breast, posterior depth).There is an abnormally enlarged right axillary lymph node, measuring 33 x 23 mm, which is a proven metastatic node. A marker clip is present within the lymph node. There are a few lymph nodes with mild cortical thickening in the right axilla. LEFT BREAST:No abnormal enhancement is seen in left breast. A few lymph nodes with mild cortical thickening are present in the left axilla.
1. Proven carcinoma in the right breast with a metastatic lymph node in the right axilla.2. No MR evidence for malignancy in the left breastBIRADS: 6 - Known cancer.RECOMMENDATION: X - No Letter.