Clinical question: MS; follow-up progression. Signs and symptoms: Paresthesia. Nonenhanced brain MRI:There is significant technique difference between the 2 exams for comparison. Current study is performed utilizing dedicated MS protocol with 2 mm slice thickness and compared to prior study standard brain MRI with 5 mm slice thickness.Within this limitation examination demonstrate mild progression of disease since prior study which is most noticeable in the right frontal subcortical white matter.Extensive supratentorial findings are demyelinating disease of the periventricular and subcortical white matter as well as extensively of the corpus callosum and bilateral thalami are again noted. Diffuse FLAIR hyperintensity in the upper most visualized cervical cord is also again.Mild prominence of cortical sulci and ventricular system as well as cerebellar and vermian folia for patient of stated age is noted.Signal void of major intracranial arterial branches are identified.
1.Although difficult to compare with the prior exam due to significant technique difference there is suggestion of interval progression of disease and supratentorial brain since prior exam as detailed.2.Extensive findings of demyelinating disease in the supratentorial brain parenchyma and to a lesser degree in the posterior fossa is again noted. 3.Diffuse FLAIR hyperintensity of partially visualized upper cervical cord is again noted.4.Prominence of cerebral cortical sulci and cerebellar-vermian folia and minimally of the lateral ventricles for patient stated age of the tail.