Splenium lesion seen before monitoring: speech issues, ESRD, and treated pseudotumor cerebri. There has been interval resolution of the abnormal T2 hyperintense focus in the splenium of the corpus callosum. The rest of the brain parenchymal signal is unremarkable. There is mild diffuse prominence of the sulci and ventricles, which appears to be new since the prior MRI. There is no evidence of intracranial hemorrhage, mass, or acute infarct. There is no midline shift or herniation. The major cerebral flow voids are intact. There is diffuse thickening and hypointensity of the skull. The orbits now appear unremarkable with resolution of prominent subarachnoid spaces in the optic nerve sheaths.
1. Interval of the signal abnormality in the splenium of the corpus callosum, which is compatible with transient splenial hyperintensity. 2. Interval resolution of prominent subarachnoid spaces in the optic nerve sheaths related to prior pseudotumor cerebri. Likewise, interval mild diffuse prominence of the sulci and ventricles may be related to treatment effects.3. Diffuse thickening and hypointensity of the skull may be related to renal osteodystrophy.