Female, 49 years old, with multiple sclerosis, assess for progression. Numerous T2 hyperintense lesions are evident in the juxtacortical and periventricular regions of the cerebral hemispheres as well as the corpus callosum, within and around the basal ganglia, brainstem and cerebellum. Many of these lesions demonstrate moderate to marked T1 hypointensity. None of the lesions shows any definite pathologic enhancement. While some lesions are better visualized than on the prior examination, this is felt to be primarily due to differences in technique. No definite or convincing evidence of any new or growing lesion is seen. The corpus callosum is thinned and there is evidence of parenchymal volume loss but these findings are also similar to the prior exam. No abnormal extra-axial collections are seen. No significant generalized mass effect is detected. The ventricles are stable in size and morphology.
Numerous parenchymal lesions are redemonstrated compatible with the diagnosis of multiple sclerosis. When compared to prior examination, no definite or convincing evidence of radiologic disease progression is seen.