Prior intrathecal MTX: gait difficulty and cognitive symptoms. There appears to be mild disproportionate enlargement of the lateral and third ventricles, as well as a prominent cerebrospinal fluid flow jet in the third ventricle. There is diffuse patchy cerebral white matter T2 hyperintensity. There is no evidence of intracranial hemorrhage, mass, or acute infarct. There is no midline shift or herniation. The major cerebral flow voids are intact. The skull, paranasal sinuses, and scalp soft tissues are grossly unremarkable. There are bilateral lens implants.
1. Findings suggestive of normal pressure hydrocephalus.2. Diffuse white matter abnormality may represent sequela of chemotherapy versus chronic small vessel ischemic disease.