 There are moderate new periventricular and subcortical white matter T2 hyperintense lesions, many of which are perpendicular in orientation to the lateral ventricles, and ovoid in shape. There are tiny signal abnormalities in the corpus callosum body and splenium on the coronal T2 images suggesting possible small T2 hyperintense lesions (for example series 8 images 25, 27 and 29). There is no suspicious enhancement or intracranial mass. There is no acute infarct, mass effect or midline shift. The hippocampi show symmetric volume and signal. There is diffuse low T1 signal of the osseous marrow without discrete lesion, nonspecific and may be related to predominance of red marrow in a patient of this age, or due to marrow-replacing process. Clinical correlation is advised.
1.Interval development of numerous nonenhancing (greater than 15) periventricular and subcortical white matter T2 hyperintense lesions, many of which are perpendicular to the lateral ventricles, nonspecific but favored to represent demyelinating lesions versus chronic small vessel ischemic changes. Differential diagnosis however includes infectious/inflammatory and vascular etiologies.2.No intracranial mass or evidence of mesial temporal sclerosis.