History of peak 53 mutation. Presents for cancer screening. SOFT TISSUES OF THE NECK: No significant abnormality noted.CHEST:LUNGS AND PLEURA: No significant abnormality notedMEDIASTINUM AND HILA: No significant abnormality notedCHEST WALL: No significant abnormality notedABDOMEN:LIVER, BILIARY TRACT: No significant abnormality notedSPLEEN: No significant abnormality notedPANCREAS: No significant abnormality notedADRENAL GLANDS: No significant abnormality notedKIDNEYS, URETERS: No significant abnormality notedRETROPERITONEUM, LYMPH NODES: No significant abnormality noted.BOWEL, MESENTERY: No significant abnormality noted.BONES, SOFT TISSUES: No significant abnormality notedOTHER: No significant abnormality notedPELVIS:PROSTATE, SEMINAL VESICLES: No significant abnormality notedBLADDER: No significant abnormality notedLYMPH NODES: No significant abnormality notedBOWEL, MESENTERY: No significant abnormality notedBONES, SOFT TISSUES: No significant abnormality notedOTHER: No significant abnormality notedFEMURS: Within the distal diaphysis of the right femur there are several distinct adjacent very well-defined lobular medullary lesions which are mildly hyperintense on T1-weighted imaging relative to skeletal muscle and is homogenously hyperintense on T2-weighted imaging. There is mild expansion of the mid/distal femoral diaphysis. There is suggestion of peripheral sclerosis of the lesions. The extent of abnormality measures 10.2 cm in length (series 1001/13). There is no associated restricted diffusion or cortical breakthrough evident. There appears to be thin peripheral enhancement of the lesion, however this was not a dedicated post-contrast study.
Incompletely characterized lesions involving the distal right femoral diaphysis likely representing a benign etiology such as non-ossifying fibroma. Further evaluation with radiographs and dedicated imaging is recommended to exclude a less likely diagnosis of sarcoma. These findings and recommendations were discussed with the referring physician Dr. Onel. 