Stage 4 neuroblastoma post induction chemotherapy, resection, auto transplant, and radiation therapy (C7 to T12 and L2 to L3 spine in September, 2015) at outside hospitals and completion of antibody therapy: assess for disease. There are post-radiation effects throughout the thoracic spine, with diffuse fatty marrow replacement. There is enhancement and sclerosis surrounding the basivertebral vein in the T8 vertebral body. There is also heterogeneous enhancement and sclerosis of the C6 and C7 vertebrae. There is no residual tumor in the thoracolumbar junction region. The vertebral body heights and alignment are preserved. The spinal cord appears unremarkable. There is no significant spinal canal stenosis. The spinal cord displays normal signal and morphology. The paravertebral soft tissues are unremarkable.
Treatment effects in the spinal column with resolution of the tumor in the thoracolumbar junction region. Nonspecific enhancement and sclerosis in the C6, C7, and T8 vertebral bodies may be reactive bone marrow or treatment effect versus less likely neoplastic in the setting of a negative recent MIBG scan.