Female, 20 years old, with multiple sclerosis, assess efficacy of current DMT. Multiple small T2 hyperintense and mildly T1 hypointense lesions are seen mostly clustered in the bilateral periventricular regions. As before, some of these lesions extend to the corpus callosum and are oriented radially relative to the ventricles. Accounting for differences in technique between scans, no clearly new or growing lesions are seen. However, one lesion in the right corona radiata has decreased in size (see image 50 series 801).One punctate focus of enhancement is seen within the right centrum semiovale (image 120 series 1201), unchanged from the prior exam. Elsewhere, no definite pathologic enhancement is seen. No edema or mass effect is observed. There are no abnormal extra-axial fluid collections. The ventricles are normal in size and morphology. Brain parenchymal volume is preserved.
Multiple lesions are redemonstrated compatible with the diagnosis of multiple sclerosis. No definite new or growing lesions are observed. However, one rather prominent lesion on the prior examination in the right corona radiata has clearly decreased in size. One punctate focus of enhancement in the right centrum semiovale is unchanged and may simply represent a small vascular structure.