Please evaluate for any signs of progressive disease since last MRI scan: Congenital microcephaly, severe intellectual disability, loss of some acquired language since about age 5, altered responsiveness after a fall 4 weeks ago. There is redemonstration microcephaly and marled bilateral colpocephaly with thinning of the brain parenchyma in the posterior cerebral hemispheres and a relatively simplified gyral pattern. The posterior portions of the corpus callosum appear to be deficient or markedly thinned as well. The brainstem and vermis of the cerebellum are mildly hypoplastic. There is no evidence of intracranial hemorrhage, mass, or acute infarct. There is no midline shift or herniation. The major cerebral flow voids are intact. The orbits are grossly unremarkable. There is diffuse paranasal sinus mucosal thickening and secretions. There is a right frontal scalp contusion.
1. Redemonstration microcephaly and marled bilateral colpocephaly with thinning of the brain parenchyma in the posterior cerebral hemispheres and a relatively simplified gyral pattern, as well as mild hypoplasia of the vermis and brainstem. 2. Right frontal scalp contusion, but no evidence of acute intracranial hemorrhage.3. Findings suggestive of pansinusitis.