the present invention relates to the field of film materials for biosensors , in particular to a film for biosensors and a preparation method . provided is an organosilicon polymer , the raw materials thereof comprising the following components : at least one active organosilane , at least one curing agent , at least one optional hydrophilic copolymer and at least one optional regulator and / or filling . the membrane prepared from the provided organosilicon polymer has outstanding oxygen permeability and is adjustable in water absorption rate , and can put regulation and restriction on the diffusion of analytes and interferents . meanwhile , the provided organosilicon polymer film also has indispensable physical strength and superior biocompatibility , and can serve as a multifunctional polymer film material for biosensors , such as anti - interference layer , analyte regulating layer and biocompatible layer .