the current invention relates to encapsulation methods comprising alginate - based microencapsulation for the immune - protection and long - term functioning of biological material or therapeutics . the biological material or the therapeutics are encompassed by a membrane formed by jellifying an alginate polymer . specifically , although by no means exclusively , the encapsulation system is intended for use in allo - or xenotransplantation . the membrane provides for a protective barrier of the encapsulated material , ensuring the longevity and preventing unwanted influences from outside the barrier , such as inflammatory reactions or immune - responses . the invention is furthermore directed to methods of producing and providing the encapsulated products for use in cell therapies . the therapeutic products obtained by the encapsulation method may provide a method for ameliorating of treating a range of conditions .