described herein is a particular type of pharmaceutical tablet , for oral use , which is formed by one or more layers , and is specifically designed for controlled release of active principles that present problems of bio - availability linked to absorption in the gastro - intestinal tract , and in particular active principles that present an erratic and unpredictable absorption linked to the presence or absence of food at the level of the stomach and / or of the first portion of the small intestine , the said pharmaceutical form being characterized in that it is completely coated with one or more films of a biocompatible and biodegradable polymeric material .