a method and composition to inhibit the enzyme nitric oxide dioxygenase and therefore accumulate nitric oxide in cells or tissues . by preventing no removal , the inhibitors may effect cellular signaling , modulate vasotension , enhance o 2 delivery to tissues , and provide antibiotic and / or antineoplastic effects . inhibitors include compounds that bind to the iron in the heme portion of nod , and include allicin and azoles .