a system for analyzing a biological sample may include at least one sample acquisition stage comprising a sample acquisition device for acquiring the biological sample from a sample source ; a droplet generator device for forming a droplet wrapped in an immiscible carrier fluid , wherein the wrapped droplet comprises at least the biological sample and a reagent , the droplet generator configured to receive the biological sample transferred from the sample acquisition device ; a collection vessel for collecting the wrapped sample droplet from the droplet generator , the vessel configured to contain a carrier fluid for receiving and protecting the sample droplet ; and an analysis system for analyzing the wrapped sample droplet and detecting products of a polymerase chain reaction .