a dual - sided biomorphic polymer - based microelectrode array and method of fabricating the same . a measurement probe fabricated from a polymer consisting of two sides each with an array of paired recording sites for the measurement of molecules in an aqueous biological or chemical environment . enzyme - based coatings are placed on microelectrodes of one measurement probe side specific to analytes of interest , and are coupled with a similar but non - functional protein matrix coating on the microelectrode on the opposite side to yield two distinct recording sites for subtraction of interferents , noise and non - faradaic background current . microelectrodes are arranged with variable spacing between each to match a variety of brain structures affording a biomorphic array allowing simultaneous recordings at multiple target depths and coordinates from one measurement probe system . the fabrication method uses photolithographic techniques where each dual - sided biomorphic polymer - based microelectrode array is cut out using lithography , allowing for multiple different or identical designs that can be simultaneously patterned on a single polymer wafer and improved microelectrode tip that is tapered for improved tissue penetration .