this invention relates to a hollow fiber membrane module to be used in industrial fields such as the semiconductor industry , food processing industry , pharmaceutical industry , and medical industry , and to a method for the production thereof . permselective hollow fiber membranes having rigidity are cheese - wound in a plurality of layers , thereby forming a hollow fiber membrane bundle . one terminal part of this hollow fiber membrane bundle together with a case is adhered and solidified with a thermally molten mass of thermoplastic resin , thereby forming a solidified part . this solidified part is cut to form a sealed part serving to open terminal parts of the hollow fiber membranes .