this relates to a composition for forming a biologically active anatomical occlusion typically within the vasculature of a patient . more particularly , it concerns an occlusive agent which may be made from a precursor composition containing at least one biodegradable , polymeric component and at least one biologically active agent . the occlusive agent may further include solid or dissolved radio - opacifiers and known vaso - occlusive devices . the resulting occlusion , a bioactive solid , encourages cellular attachment and growth while maintaining favorable handling , deployment , and visualization characteristics .