a process for making an oligo functionalized co - polyisocyanopeptide , wherein the process includes the steps of : i ) copolymerizing a first comonomer of an oligo functionalized isocyanopeptide grafted with a linking group and a second comonomer of a non - grafted oligo functionalized isocyanopeptide , wherein the molar ratio between the first comonomer and the second comonomer is 1 : 500 and 1 : 30 and ii ) adding a reactant of a spacer unit and a cell adhesion factor to the copolymer obtained by step i ), wherein the spacer unit is represented by general formula a - l - b , wherein the linking group and group a are chosen to react and form a first coupling and the cell adhesion factor and group b are chosen to react and form a second coupling , wherein the first coupling and the second coupling are independently selected from the group consisting of alkyne - azide coupling , dibenzocyclooctyne - azide coupling , oxanorbornmadiene - based - azide couplings , vinylsulphone - thiol coupling , maleimide - thiol coupling , methyl methacrylate - thiol coupling , ether coupling , thioether coupling , biotin - strepavidin coupling , amine - carboxylic acid resulting in amides linkages , alcohol - carboxylic acid coupling resulting in esters linkages and nhs - ester - amine coupling and wherein group l is a linear chain segment having 10 - 60 bonds between atoms selected from c , n , o and s in the main chain .