the present invention features linear and three - dimensional supramolecular materials self - assembled from block co - polymers comprising oligo . the block copolymers assemble into fibrils , micelles , or matrices . the fibrillar materials are sensitive to oxidation , which leads to decreased oes block hydrophobicity and crystallinity , and increased water solubility of the polymer constituents . molecular loading options , coupled with oxidative sensitivity , allow implantable or injectable fibrillar suspensions or cross - linked three - dimensional matrices to demonstrate significant biomedical potential , especially in the context of extracellular and intracellular molecular delivery and applications related to infection and disease .