a novel solid pharmaceutical dosage formulation of hydrophobic drugs is disclosed , which provides enhanced dissolution and improved bioavailability . the formulation comprises : a base substrate comprising a first polymer ; a deposit , comprising a therapeutic amount of a hydrophobic drug , deposited on the base substrate ; a cover substrate comprising a second polymer , the cover substrate covering the deposit and joined to the base substrate by a bond that encircles the deposit ; and a dissolution - enhancing amount of a surfactant , disposed within a carrier that is segregated from , but in contact with , the deposit . in another embodiment , the dosage form may include any pharmaceutically acceptable additive , disposed within a carrier that is segregated from , but in contact with , the deposit . in a preferred embodiment , the hydrophobic drug is deposited electrostatically on the base substrate .