this invention reports ciprofloxacin - encapsulated polymeric nanoparticles and its antibacterial potential with a variety of gram positive and gram negative pathogenic bacteria . cip - encapsulated nanoparticles of diethylaminoethyl cellulose are prepared by the multiple emulsion solvent evaporation method . cip - encapsulated nanoparticles showed superior effectiveness to inhibit the growth of bacteria in - vitro .