a new and useful process is disclosed for manufacturing a device for use in a bioprocess , comprising : providing solid support means insoluble in water or organic solvent solutions ; coating said solid support means with water - based polymeric film means capable of applying one or more biomaterials ; and adsorbing or covalently bonding at least one functional biomaterial to said polymeric film means . the polymeric film means , for example , can be used to coat antigens , antibodies , haptens , enzymes , living bacteria , yeasts , etc . to a glass support material , e . g ., a glass tube , with surprising retention of the biomaterial &# 39 ; s essential characteristic properties . the solid support means include but are not limited to those comprising glass , ceramics , metals , polymers and woods . the device of the invention is particularly useful in various immunoassays using a solid support for separation of phases .