the invention relates to synthetic , bioabsorbable polymer materials and implants , like fibres , sutures , meshes and other tissue management , wound closure or tissue engineering devices , which contain : a ) a bioabsorbable polymeric matrix ; b ) antibiotic and / or anti - inflammatory agent particles or mixture thereof , dispersed in the matrix , and c ) optionally an additive agent to facilitate device recognition and / or handling to facilitate the use and application of finalized product . in the matrix , cavities around the particles are induced by mechanical processing of the matrix phase . a preferred embodiment of the present invention is a device that provides a sustained release of antibiotic agent over several days to several weeks for the prevention or treatment of infection . the sutures may be effectively implanted into or in the vicinity of : 1 ) infected tissue , 2 ) potentially infected tissue , or in tissues where infection , should it occur , leads to disastrous consequences .