a method of making a composition comprising reacting an isocyanate group - containing component having an average functionality of at least 2 ; and an active hydrogen group - containing component having an average functionality of at least 2 to form a composition that is biodegradable , a solid at 22 ° c . and below , and has pressure sensitive adhesive properties at a temperature of 37 ° c . and relative humidity of 100 %. a method of using the composition therefore to adhere polymer meshes or films to biological tissue is also disclosed .