this invention deals with a carboxyl - bearing , amphiphilic , solid copolyester stent coating composition for multifaceted prevention of vascular restenosis through a plurality of physicopharmacological modes . the composition includes one or more bioactive compounds and a copolymerization product of polyalkylene glycol , end - grafted with one or more cyclic monomer and treated further to introduce carboxyl - bearing end - or side - groups . the invention also deals with bioactive agents in an ionically conjugated form . the present coating may be applied to a metallic or an absorbable polymeric stent for use in preventing vascular restenosis .