the present invention is related to a polymeric vehicle for delivery of bioactive agents , and preferably , for the delivery of one or more bioactive agents . the invention is also directed to a percutaneous device securing and drug delivery device comprising , as a component thereof , a material which delivers antimicrobial and / or other wound - healing factors at the site of the insertion of the catheter into the body . the device , when applied as described herein , provides complete anti - microbial coverage around the entry point of a percutaneous device and , preferably for a length greater than the diameter of the device . the present invention is also directed to methods for using such devices in combination with percutaneous devices primarily to reduce site infections .