a formulation comprising t3 / vip nanoparticles , wherein the t3 / vip nanoparticle comprises both t3 and vip encapsulated or immobilized on a bioabsorbable polymer . the invention further provides for methods of making a formulation comprising a t3 / vip nanoparticle . the invention further provides for methods of treatment utilizing said t3 / vip nanoparticle .