the present invention relates to a compound having anti - ks and anti - hiv pharmaceutical activity which comprises an hcg - like inhibitory protein and fragments or derivatives thereof , said protein and fragments thereof are isolated from a biologically active fraction of apl - hcg , wherein said protein has a molecular weight of about 3 , 500 or of about 13 , 000 dalton , and wherein said protein and fragments thereof are adsorbed polypropylene plastic supports . a pharmaceutical composition for the prevention and / or treatment of kaposi &# 39 ; s sarcoma and hiv which comprises an therapeutically effective amount of at least one compound of the present invention in association with a pharmaceutically acceptable carrier . a method for the prevention , treatment and / or reduction of kaposi &# 39 ; s sarcoma and hiv expression in aids patients , which consists in administering the composition to the patient .