the invention refers to coatings on different substrates , whereby a hydrophilic polymer layer is bound by means of a polymer adhesion promoter layer to a substrate . a method for the production of these layer systems is disclosed as well . the layers according to the invention can be used as immobilization matrix and for the suppression of non - specific protein adsorption in biosensors , maldi targets and other bioanalytical devices . furthermore they can be used for the bio - compatibilization of implants and for the coating of contact lenses . optical elements , which are provided with such coatings , do not fog up any more . beyond that the layers are dirt - deflecting and / or self - cleaning .