a chemically modified and activated , hydroxyl - group - containing , natural or synthetic , polymeric solid body surface is disclosed , as well as a process for the activation of such solid body surfaces by means of organo - silanes and , if necessary , homo - or heterobifunctional reagent . the surfaces are used for the stable , simple and economical binding of proteins , nucleic acids , low - molecular ligands , cells , microorganisms and other biological materials , in biology , biotechnology and medicine .