methods and apparatus are set forth for preparing and delivering bone cement from a powdered polymer component and a liquid monomer component by simultaneously injecting the powdered and liquid components , stored in separate component chambers , into an evacuated mixing chamber under the effect of the vacuum ; by uniformly mixing the components in the mixing chamber ; and by delivering the cement formed by the polymerization process , as needed in an operative setting , utilizing a single ready to use device . the uniform mix is achieved by simultaneously subjecting the contents of the component chambers to the effects of the mixing chamber &# 39 ; s vacuum via separate one way nozzles , interconnecting the component chambers to the mixing chamber , which cause the powder to be broadcast and liquid to be sprayed into the mixing chamber . the nozzles are designed and oriented in a predetermined manner , to cause the components to interact at a preselected distance within the mixing chamber , to assure uniform powder saturation and a thorough mix which yields a homogeneous reaction product .