ophthalmic compositions containing biocompatible , bioadhesive polymerizable amphipathic mesophase materials useful for repairing retinal tissue tears or retinal detachments are disclosed . in one embodiment , the polymerizable materials , which comprise substituted fluoroalkyl or perfluoroalkyl monomers having anionic , cationic , and / or nonionic surface active functionality in the unsaturated fluorophobic ends , are polymerized in vivo to provide effective , long - lasting repair of torn , ruptured or detached retinal tissue . ophthalmic applications of these materials are not limited to retinal repair .