a framed panel and related method of manufacture are disclosed . a framed panel unit includes a panel along the edge of which thermoplastic frame members are disposed . the frame members have first and second opposed side walls which define a channel for receiving the edge of the panel . the channel of each frame member has spacers between the panel and each side wall for spacing the panel from the side walls . prior to welding together the ends of the frame members , the spacers retain the frame members on the panel . the panel may include multiple opposed sheet members with a spacer between the sheet members spacing them apart , and a reactive thermoplastic sealant material bonding the sheets to the frame members . an associated method of forming a named panel , frame members for a panel , and a spacer component for use in mounting a panel within a channel of a frame member are also disclosed .