in one embodiment , there is provided a method for producing a sterilized and pyrogen - free bag for storing fluids . the method includes providing a bag comprised of polymeric film and heating the bag to at least approximately 253 degrees celsius for at least approximately 30 minutes for sterilization and pyrogen removal . the polymeric film is a polymer selected from the group of poly ; polytetrafluoroethylene ; a perfluoroalkoxy polymer ; poly ; polyperfluoro ; poly ; poly ; poly ; tetrafluoroethylene - co - hexafluoropropylene - co - vinylidene fluoride terpolymer ; poly ; poly ; and suitable mixtures thereof .