cell delivery matrices and methods for facilitating local delivery of adipose derived endothelial cells to a target tissue , body cavity , or joint are described . the cell delivery matrix may be a three - dimensional matrix scaffold comprising fibrin derived from the patient &# 39 ; s own body . the cell delivery matrix may be biocompatible and semi - permeable . the cell delivery matrix used in the methods of the invention may be comprised of any degradable , bioabsorbable or non - degradable , biocompatible polymer . regenerative therapies comprising implanting in the subject cell delivery matrices localizing adipose derived endothelial cells are described . the cell delivery matrices maintain the adipose derived endothelial cells at the target for a therapeutically effective amount of time . the adipose derived endothelial cells can be allogenic or syngenic to the subject . the endothelial cells may be delivered alone or in combination with other therapeutic agents .