a soft tissue prosthesis for repairing a defect of an abdominal wall or a pelvic cavity wall , comprising : a three - dimensional mesh sheet comprising at least two types of yarn interlooped or intertwined to define at least two layers , wherein one of the at least two layers is substantially non - biodegradable and porous to allow for tissue ingrowth and another of the at least two layers is substantially biodegradable ; and an adhesion barrier in the form of a film , foam or gel , the adhesion barrier polymerized to , and entrapping therein , at least some of the yarns of the substantially biodegradable layer , the substantially biodegradable layer making a connection between the adhesion barrier and the substantially non - biodegradable layer to decrease the likelihood of delamination therefrom , the adhesion barrier being an external layer on a first side of the prosthesis and the substantially non - biodegradable layer being an external layer on the side of the prosthesis opposite the first side , the substantially biodegradable layer being positioned between the substantially non - biodegradable layer and the adhesion barrier .