polymeric materials including polyurethanes , polyesters , polyolefins , polyamides , polysiloxanes , vinylic and acrylic polymers are rendered biocompatible by including with the polymeric material hyaluronic acid or a salt thereof . the hyaluronic acid may be coated onto the surface of the polymeric material , dispersed throughout the body of the polymeric material , or both . the hyaluronic acid on the surface of the polymeric material may optionally be cross - linked . the biocompatible polymeric materials are used in the making of various prosthetic devices including heart valves , intraocular lenses , vascular grafts , pacemaker leads and the like .