this invention relates to a quick method for preparation of photorcactive polymers and immobilization of biomolecules onto these polymers . particularly , this invention relates to a microwave - mediated rapid and efficient method for the preparation of photoreactive polymer having at least one photoactivable functional group capable of forming a covalent bond with the biomolecule in a photochemical reaction . any matrix either organic or inorganic having a nucleophilic group preferably , amino , hydroxyl or thiol group can be modified by the invented method . immobilization of biomolecules onto the photoreactive polymers was carried out by uv radiation . the method has applications for inmmobilization of bio - molecules irrespective of their functional groups in the fields of molecular biology , proteomics , genomics , diagnostics , chemical or biochemical industry and other related fields .