the implantable scaffold matrix composition for osteogenic regeneration has a biodegradable polymer material selected from the group consisting of one or more of polylactic acid , polyglycolic acid , or polycaprolactone , or any combination thereof to provide a time release delivery of an osteogenic effect and further has a pharmaceutical composition selected from the group consisting of one or more of ibuprofen , non - steroidal anti - inflammatory drugs , acetaminophen , or naproxen sodium or any combination thereof and wherein the implantable composition has a primary and a secondary time release . the primary time release being one of the polymer compositions ; each time release extending occurring between 0 days and 19 days , both not being at 0 days . in a preferred composition , the scaffold has an organic material for inhibiting osteoclast selected from a group consisting of one or more of galardin , decorin , actinonin , marimastat , batimastat , and phosphodiesterase type 4 or any combination of osteoclast inhibitors .