a microtitration plate has a frame made of a first stiff plastic and having a plate with multiplicity of holes , and a multiplicity of vessels made of a second plastic suited for the pcr and / or exhibiting permeability to oxygen , which are fixedly connected to the plate by directly molding them to the holes , which have a receiving portion protruding from an underside of the plate , and which are accessible from an upper surface of the plate through apertures .