a biocontainer film enhanced with an abrasion resistant or “ cut - proof ” substrate . such substrates can be combined with current biocontainer materials , via various techniques of embedding , coextrusion or laminating , to maintain the cleanliness and low extractables already validated for biotech manufacturing . the substrate of choice may be constructed from materials known to be more resistant to abrasion and sharp razor type cuts or from materials oriented in such a way to prevent puncture to occur . the new substrate must also be flexible to allow for typical folding as demonstrated by current packaging practices . the new substrate may be constructed from materials other than polymers such as metal , glass or carbon or in combination with polymers . a non - constrained pressure test is also disclosed .