the invention relates to a library of 298 peptides useful for formulating a novel therapeutic hiv vaccine . the peptide sequences were selected on the basis of calibration of molecular structure properties of hiv - 1 or host cell proteins . a mixture of d - and l - amino acids or all d - amino acids are used to synthesize the stereoisomer peptides for the purpose of increasing their stability . the peptides are expected to have the ability to potently inhibit functioning of proteins important for hiv infection . a plural of the peptides are conjugated together with a biocompatible polymer , preferably hpma to further increase stability and solubility , decrease drug toxicity , and potentially evade multidrug resistance and exert cooperative effect , since some peptides are the ligands for host proteins such as integrin , trombospondin , vegfr and ledgf which can bring the therapeutic peptides to the target cells and therefore help disrupt the interactions between the host proteins and the hiv proteins .