How to Give a Dog Benadryl
To give a dog Benadryl, give it 1 milligram per pound it weighs. For example, if your dog weighs 14 pounds, you can give it 14 milligrams of Benadryl every 8 hours. When possible, give your dog its Benadryl with food to lessen the chance of vomiting and make it easier for the dog to take. You can also apply Benadryl topically to the skin as needed, though it's not as potent as the oral medication. If your dog seems excessively lethargic, has trouble breathing, or is agitated, stop using Benadryl immediately.
Dose the dog correctly. Generally, you give a milligram per pound of dog. You can give it every 8 hours or so. So if your dog weighs 14 pounds, you can give 14 milligrams of Benadryl every 8 hours. However, it's always best to check with the vet for an appropriate dose. Using children's Benadryl can make dosing easier, as it comes in smaller doses. In severe allergic reactions, a slightly higher dose may be appropriate, such as 2 milligrams per pound. Pills are usually easiest because most dogs don't like the flavor of the liquid. However, you can use liquid Benadryl (the children's formula). Usually, every 5 milliliters of liquid has 12.5 milligrams of Benadryl. Give it with food, if possible. You can give Benadryl without food. However, using food will lessen the chances of drooling and vomiting. Plus, it will make it easier to get your dog to take it. For instance, you can place the pill on a small piece of bread smeared with peanut butter, which your dog will likely gobble down. Apply it topically as needed. Another option is to apply the Benadryl to the skin. You can use a spray, cream, or stick. However, be sure not to apply more than a couple of times a day, and don't combine it with oral Benadryl, as that can lead to overdose. It's not as effective as an oral medication, but it can help some. The Benadryl will have little benefit if your dog licks it off. Cover the area with a bandage or put a t-shirt or cone collar on your dog to prevent it from licking the irritated area. Watch for a reaction. While Benadryl is generally safe, any medication can cause a reaction if your dog happens to be allergic to it. Watch for stomach issues such as diarrhea and vomiting. Also notice if your dog is less interested in eating or is having trouble breathing. Agitation or a fast-beating heart is also an issue. Call your vet if you notice any of these side effects. Also, some sleepiness is to be expected with Benadryl. However, if your dog seems excessively lethargic, is having trouble waking up, or is non-responsive, you should call your vet. Discuss it with your vet. While Benadryl is generally safe for dogs, every dog is different. It's best to talk to your vet before giving your dog Benadryl, to make sure it will be safe and to get a dose recommendation. Technically, Benadryl hasn't been approved by the FDA for cats and dogs, but most vets agree it's safe. Discussing dosage with your vet is important because dogs can overdose on Benadryl. Treat anxiety with Benadryl. One use for Benadryl is treating anxiety in dogs. For instance, some dogs have storm anxiety, and Benadryl can help calm them down. Often, it works best to give them Benadryl ahead of the storm. Similarly, it can also help out in the car. It can calm anxiety, and it will also assist with nausea from motion sickness. Use Benadryl for allergies and bug bites. Another common use for Benadryl is to treat allergies. Dogs with allergies tend to scratch more, and if your dog has been diagnosed with allergies, Benadryl can help alleviate the symptoms. However, some experts question the effectiveness of Benadryl for general allergies. While it can be helpful for reactions like bee stings and hives, it may not help as much with the itchy skin that comes with canine allergies. Give Benadryl to your dog for insomnia. One of Benadryl's side effects is drowsiness. In fact, it's used in many over-the-counter sleep aids. That's why it can help your dog with insomnia if you give it to the dog before bedtime. Ensure your product only contains diphenhydramine. In the United States, most products with the Benadryl label only contain diphenhydramine. However, this ingredient has fallen out of use in other countries. For instance, in the UK, cetrizine is the active ingredient instead. While this ingredient is also dog-safe, it won't have all the same effects. 
Dose the dog correctly. Give it with food, if possible. Apply it topically as needed. Watch for a reaction. Discuss it with your vet. Treat anxiety with Benadryl. Use Benadryl for allergies and bug bites. Give Benadryl to your dog for insomnia. Ensure your product only contains diphenhydramine. 