page_title: Nucleoside-diphosphatase
hierarchical_section_title: Nucleoside-diphosphatase
caption_attribution_description: English: Nucleoside diphosphatase homodimer + 1 acetate (green-red) + 2 Ca (l.blue), Human
context_page_description: In enzymology, a nucleoside-diphosphatase is an enzyme that catalyzes the chemical reaction
  a nucleoside diphosphate + H₂O a nucleotide + phosphate
  Thus, the two substrates of this enzyme are nucleoside diphosphate and H₂O, whereas its two products are nucleotide and phosphate.
  This enzyme belongs to the family of hydrolases, specifically those acting on acid anhydrides in phosphorus-containing anhydrides. The systematic name of this enzyme class is nucleoside-diphosphate phosphohydrolase. Other names in common use include thiamine pyrophosphatase, UDPase, inosine diphosphatase, adenosine diphosphatase, IDPase, ADPase, adenosinepyrophosphatase, guanosine diphosphatase, guanosine 5'-diphosphatase, inosine 5'-diphosphatase, uridine diphosphatase, uridine 5'-diphosphatase, nucleoside diphosphate phosphatase, type B nucleoside diphosphatase, GDPase, CDPase, nucleoside 5'-diphosphatase, type L nucleoside diphosphatase, NDPase, and nucleoside diphosphate phosphohydrolase. This enzyme participates in purine metabolism and pyrimidine metabolism.
context_section_description: In enzymology, a nucleoside-diphosphatase (EC 3.6.1.6) is an enzyme that catalyzes the chemical reaction
  a nucleoside diphosphate + H₂O  a nucleotide + phosphate
  Thus, the two substrates of this enzyme are nucleoside diphosphate and H₂O, whereas its two products are nucleotide and phosphate.
  This enzyme belongs to the family of hydrolases, specifically those acting on acid anhydrides in phosphorus-containing anhydrides.  The systematic name of this enzyme class is nucleoside-diphosphate phosphohydrolase. Other names in common use include thiamine pyrophosphatase, UDPase, inosine diphosphatase, adenosine diphosphatase, IDPase, ADPase, adenosinepyrophosphatase, guanosine diphosphatase, guanosine 5'-diphosphatase, inosine 5'-diphosphatase, uridine diphosphatase, uridine 5'-diphosphatase, nucleoside diphosphate phosphatase, type B nucleoside diphosphatase, GDPase, CDPase, nucleoside 5'-diphosphatase, type L nucleoside diphosphatase, NDPase, and nucleoside diphosphate phosphohydrolase.  This enzyme participates in purine metabolism and pyrimidine metabolism.
caption: Nucleoside-diphosphatase dimer, Human
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