page_title: Response regulator
hierarchical_section_title: Response regulator
caption_attribution_description: English: The structure of the Escherichia coli protein CheY, a response regulator protein involved in chemotaxis, with the aspartate phosphorylation site (Asp 57) highlighted in green. Rendered using PyMol from PDB ID 3CHY.
context_page_description: A response regulator is a protein that mediates a cell's response to changes in its environment as part of a two-component regulatory system. Response regulators are coupled to specific histidine kinases which serve as sensors of environmental changes. Response regulators and histidine kinases are two of the most common gene families in bacteria, where two-component signaling systems are very common; they also appear much more rarely in the genomes of some archaea, yeasts, filamentous fungi, and plants. Two-component systems are not found in metazoans.
context_section_description: A response regulator is a protein that mediates a cell's response to changes in its environment as part of a two-component regulatory system. Response regulators are coupled to specific histidine kinases which serve as sensors of environmental changes. Response regulators and histidine kinases are two of the most common gene families in bacteria, where two-component signaling systems are very common; they also appear much more rarely in the genomes of some archaea, yeasts, filamentous fungi, and plants. Two-component systems are not found in metazoans.
caption: The response regulator CheY from E. coli, with the aspartate phosphorylation site highlighted in green. From PDB: 3CHY​.
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