page_title: Long-chain-fatty-acid—CoA ligase
section_title: Dimer interaction
hierarchical_section_title: Long-chain-fatty-acid—CoA ligase / Structure / Dimer interaction
caption_attribution_description: English: Dimer interaction
context_page_description: The long chain fatty acyl-CoA ligase is an enzyme of the ligase family that activates the oxidation of complex fatty acids. Long chain fatty acyl-CoA synthetase catalyzes the formation of fatty acyl-CoA by a two-step process proceeding through an adenylated intermediate. The enzyme catalyzes the following reaction,
  Fatty acid + CoA + ATP ⇌ Acyl-CoA + AMP + PPᵢ
  It is present in all organisms from bacteria to humans. It catalyzes the pre-step reaction for β-oxidation of fatty acids or can be incorporated in phospholipids.
context_section_description: The dimerization of LC-FACS is stabilized through a salt bridge between Asp15 of sequence A and Arg176 of sequence B.  Figure 4 shows this salt bridge between these two amino acids. The yellow line between Asp15 and Arg176 shows the salt bridge present.
caption: Figure 4. Dimerization of LC-FACS.
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