Zot Eye
The Zot Eye is a disease caused by being around ugly girls at UCI too long, effectively lowering your standards for what is attractive.

(based on UCSD's 'Triton Eye')
"Zot eye is like yellow fever"
"Dude, zot eye is for ugly girls"
"But Irvine has hot girls"
"I bet you would say that if you went to UCSD"
"FUCK, I TOTALLY HAVE ZOT EYE"