Framily
A member of your circle who is more than a friend but not a blood relative.  Combining the words friend and family.  Someone very significant in your life not in your family.  Joined by hearts and souls, not bloodlines.
Linda Smith, John Jones, Sam and Jane Doe are all people I have met over the years.  We spend holidays together, take care of each other's families when necessary.  Our Framily reunion each year rotates between houses.