Opheliac
In reference to the character Ophelia in Shakespeare's Hamlet, Opheliac is a noun meaning one who has delved into madness. The source of this word comes from Emilie Autumn's new album, titled Opheliac, along with a song sharing the title name. The album Opheliac debuted in 2006. Labeled a mix of gothic, industrial, and classical, it is by far one of the more unique blends of music available today. Emilie Autumn has put out a series of albums prior to Opheliac, and is based out of Chicago.
My sister is such the opheliac she has taken to talking to herself.