Motherfucka
Another word for motherfucker, but instead your so wasted and high that you don't even give a damn fuck no more about how you look or do because white girl over there got you hammered and banged you in the club while your cussing your friends/nightstand the fuck out...
Tony: Sorry man, I was watching tons of porn on your laptop and now it has viruses everywhere

Jack: You ugly ass motherfucka, this is the 2nd time already dammit!