Unmitigated misery
The feeling you get when you're at a party, and you say "YOLO" even though it's FUCKING ANNOYING, and drink a shitload, then 2 weeks later you're on the toilet looking at your positive pregnancy test. Also associated with when you just feel fucked. It is unparalleled misery that others laugh at until you commit suicide. Or beat them senseless.
It's fun to laugh at that cunt's unmitigated misery ^_^