Mittfortune
To invest a massive amount of your life with a single overriding focus and goal that is all encompassing. To approach realization of this ultimate desire almost totally, to be 99% of the way there - and then to suddenly, entirely, and without question or any chance of ever being able to try again - you lose it... have it all ripped from your hands just as you thought you were about to grasp the grand dream. It's all gone.
For more than 8 solid years Mitt Romney tried and lived only for the purpose of becoming President and moments before he stepped into the Oval Office it was his great mittfortune to be kicked to the curb and left with the trash.