This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Biochemistry
Best method to neasure HbA1c? 
Select and explain. 
A. lsoelectric focusing, B. Affinity chromatography, C. Ion exchange chromatography, D. Electrophoresis
C: Ion exchange chromatography
Answer: C: Ion exchange chromatography 
Explanation: Ans: C. Ion exchange chromatographyRef: Tietz T*tbook of clinical chemistry and molecular biologt, lh ed^, pg. 1443-1444Techniques based on charge differences (ion-exchange chromatography, HPLC, electrophoresis, and isoelectric focusing), structural differences (affinity chromatography and immunoassay), or chemical analysis (photometry and spechophotometry).