This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: AIIMS 2017, Subject name: Pharmacology
Drug of choice for scrub typhus is: 
Select and explain. 
A. Azithromycin, B. Ciprofloxacin, C. Doxycycline, D. Chloramphenicol
C: Doxycycline
Answer: C: Doxycycline 
Explanation: Scrub typhus is caused by rickettsia. DOC for rickettsia is Doxycycline(tetracycline). It is the DOC for all kind of typhus like endemic typhus, epidemic typhus, and other rickettsial infections like Q fever, rocky mountain spotted fever. Azithromycin is a macrolide and a protein synthesis inhibitor. Ciprofloxacin is a fluoroquinolone. Chloramphenicol is also a protein synthesis inhibitor.