This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: AIIMS 2019, Subject name: Physiology
A 36 year old female is found to have a large pituitary mass on MRI imaging. She underwent transsphenoidal hypophysectomy. Postop replacement of which of the following hormone is not needed? 
Select and explain. 
A. L-Thyroxine, B. Estradiol, C. Glucocoicoids, D. Mineralocoicoids
D: Mineralocoicoids
Answer: D: Mineralocoicoids 
Explanation: Aldosterone is majorly regulated by K+ & plasma volume The following factors play essential roles in aldosterone regulation: 1. | K+ concentration in ECF - | Aldosterone 2. | Angiotensin concentration in ECF - | Aldosterone3. | Na++ in ECF - decreases aldosterone very slightly4. ACTH from anterior pituitary - necessary for aldosterone sec but has little effect on controlling the rate of secretion in most physiological conditions. ACTH appears to play a permissive role in regulation of aldosterone of these, K+ ion conc. & RAAS are the most potent in regulating aldosterone secretion. Regulated by Hormone TSH Thyroid FSH Estrogen ACTH Glucocoicoids