This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
What does low volume of distribution of a drug mean? 
Select and explain. 
A. Low bioavailability, B. Does not accumulates in tissues, C. Low absorption, D. Not metabolized in the body
B: Does not accumulates in tissues
Answer: B: Does not accumulates in tissues 
Explanation: Ans: B. Does not accumulates in tissues(Ref: KDT 7/e p17, 18, 6/e p18)Low volume of distribution:Implies that the drug remains confined to the plasma compament without getting distributed in the body tissues.