This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
Patient is a known case of epilepsy, taking levetiracetam 1 gm BD. He is now seizure free from 2 years but he developed agitation and anger issues interfering with day to day activities as a result of the drug intake. What should be the next best step? 
Select and explain. 
A. Stop levetiracetam and sta on a different antiepileptic, B. Discontinue the drug as he is seizure free, C. Slowly taper the drug over next 6 months, D. Continue levetiracetam since a 5-year seizure free interval is needed
C: Slowly taper the drug over next 6 months
Answer: C: Slowly taper the drug over next 6 months 
Explanation: Answer- C. Slowly taper the drug over next 6 monthsStopping or switching an antiepileptic is based on seizure free period & compliance or adverse effects of the drug.Withdrawal of therapy should be gradual over 2-3 monlhs, in the question 6 months. Anti-epileptic drug therapy shouldnever he stopped abruptly. Even if new drug is to be added/replaced, the previous drug should be gradually stoppedotherwise it can lead to breakthrough seizures.