This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pediatrics
Earliest valvular lesion in a case of acute rheumatic fever is – 
Select and explain. 
A. Mitral regurgitation (MR), B. Aortic Regurgitation(AR), C. Mitral stenosis (MS), D. Aortic Stenosis (AS)
A: Mitral regurgitation (MR)
Answer: A: Mitral regurgitation (MR) 
Explanation: In rheumatic fever valvular abnormalities usually are associated with chronic disease but mitral regurgitation is seen in acute rheumatic fever.
Mitral regurgitation is the commonest manifestation of acute as well as previous rheumatic carditis.