This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Gynaecology & Obstetrics
A Rh-negative mother, who has Indirect Coombs Test (ICT), negative was given Anti-D during 28 weeks of pregnancy. Which of the following is the ideal one? 
Select and explain. 
A. Give another dose of Anti-D 72 hours postpaum depending on the baby blood group, B. Give another dose of Anti-D 72 hours postpaum irrespective of baby blood group, C. No need of additional dose since she is ICT negative, D. All of the above
A: Give another dose of Anti-D 72 hours postpaum depending on the baby blood group
Answer: A: Give another dose of Anti-D 72 hours postpaum depending on the baby blood group 
Explanation: Answer- A. Give another dose of Anti-D 72 hours postpaum depending on the baby blood groupACOG (2010) recommends anti-D immune globulin to be given prophylactically to all Rh D-negative, unsensitized women at approximately 28 weeks, and a second dose given after delivery if the infant is Rh D-positive. Before the 28-week dose of anti-D immune globulin, repeat antibocly screening is recommended to identify individuals who have become alloimmunized. Following delivery, anti-D immune globulin should be given within 72 hours.