This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
Compared to unfractionated heparin, Low molecular weight heparin (LMWH) has reliable anticoagulant action because: 
Select and explain. 
A. It interferes with thrombin and antithrombin III simultaneously, B. It is less protein bound, C. It is given subcutaneously, D. It is cleared by macrophages
B: It is less protein bound
Answer: B: It is less protein bound 
Explanation: Answer- B. It is less protein boundCompared to unfractionated heparin, Low molecular weight heparin (LMWH) has reliable anticoagulant action because it is less protein bound.Indications of LMW heparins:Prophylaxis of DVT and pulmonary embolism in high-risk patients undergoing surgery stroke or other immobilized patientsTreatment of established DVTUnstable anginaTo maintain patency of cannulae and shunts in dialysis patients and in extracorporeal circulation.