This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Anaesthesia
Which anesthetic agent can cause pain on IV adminis-tration? 
Select and explain. 
A. Ketamine, B. Propofol, C. Thiopentone, D. Midazolam
B: Propofol
Answer: B: Propofol 
Explanation: Ans: B. Propofol(Ref: Miller 6/e p318-320: Morgan 4/e p200-202: Lee 13/e p158-160).Propofol:Oil-based preparation containing soyabean oil, egg lecithin & glycerol.As it contains oil - Hence painful injection IV administration.Should be preceded or mixed with lignocaine.