This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Biochemistry
In uncontrolled diabetes mellitus, elevated triglyceride and VLDL levels are seen due to: 
Select and explain. 
A. Increased activity of lipoprotein lipase and decreased activity of hormone sensitive lipase, B. Increased activity of hormone sensitive lipase and decreased activity of lipoprotein lipase, C. Increase in peripheral LDL receptors, D. Increased activity of hepatic lipase
B: Increased activity of hormone sensitive lipase and decreased activity of lipoprotein lipase
Answer: B: Increased activity of hormone sensitive lipase and decreased activity of lipoprotein lipase 
Explanation: Answer- B. Increased activity of hormone sensitive lipase and decreased activity of lipoprotein lipaseIn uncontrolled diabetes mellitus, elevated triglyceride and VLDL levels sre seen due to increased activity of hormone sensitive lipase (which insulin inhibits) and decreased activity of lipoprotein lipase (which insulin stimalates).