This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pediatrics
A parent is homozygous and a parent heterozygous for an autosomal recessive gene. What will be the outcome – 
Select and explain. 
A. 75% children affected, B. No child affected, but all are carriers, C. 50% children affected, rest are carriers, D. 25% children affected, rest are carriers
C: 50% children affected, rest are carriers
Answer: C: 50% children affected, rest are carriers 
Explanation: Autosomal recessive disorders 

Autosomal recessive disorders are manifested in homozygous state, i.e. when both alleles at a given gene locus are mutant.
There may be following five situations -