This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
Most impoant but nonspecific regulator of iron metabolism is: 
Select and explain. 
A. Hepcidin, B. DMT I, C. Ferropoin, D. Ferritin
A: Hepcidin
Answer: A: Hepcidin 
Explanation: Ans: A. Hepcidin(Ref Robbins 91e p650 848 8/e p660)Hepcidin:Main regulator protein for iron absorption.Encoded by HAMP gene.Small circulating peptide synthesized & released from liver in response to increased intrahepatic iron levels.Proteins Involved in Iron MetabolismCeruloplasmindeg (ferrioxidase activity)DMT1degFerrireductasedeg (cytochrome b reductase I)FerritindegFerropinHeme transpoerHemojuvelinHepcidindegHephaestindegHFEdegIron-responsive element-bindingproteindegTransferrindegTransferrin receptors 1 & 2