This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Gynaecology & Obstetrics
A 32 years old female came for routine PAP smear testing. The repo came as carcinoma in situ. What is the next step? 
Select and explain. 
A. HPV-DNA testing, B. Hysterectomy, C. Conization, D. Colposcopy and biopsy
D: Colposcopy and biopsy
Answer: D: Colposcopy and biopsy 
Explanation: Answer- D. Colposcopy and biopsyRegressions typically occur within a 2-year follow-up with cytology & colposcopy.Observation - Biopsy diagnoses of CIN 1 with satisfactory colposcopy and who agree to the evaluation every 6 monthsAblative treatment - lf the lesions progress during follow-up or persist at 2 yearsTreatment options: LEEP & Cryosurgery