This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Social & Preventive Medicine
Which of the following is the best for determining the threshold for diagnosis of a positive test? 
Select and explain. 
A. Analysis of variance, B. Pearson coefficient, C. Receiver-operating characteristic curve, D. Pre-test probability
C: Receiver-operating characteristic curve
Answer: C: Receiver-operating characteristic curve 
Explanation: Ans: C. Receiver-operating characteristic curve(Ref http:ilvvwwlexjansen.com/nesteg/ne.sug10/hl/h107.pdf)Receiver-operating characteristic (ROC) curve:Defined as a plot of test sensitivity as they coordinate versus its I-specificity or false positive rate (FPR) as the x coordinate.Graphic presentation of relationship between both sensitivity & specificity.Uses:Effective method for evaluating diagnostic test's performances.Excellent way to compare diagnostic tests.Best for determining threshold for diagnosis of positive test.Helps decide optimal model through determining best threshold for diagnostic test.