This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: AIIMS 2018, Subject name: Gynaecology & Obstetrics
Possible conversion to choriocarcinoma after hydatidiform mole is denoted by all of the following, except:- 
Select and explain. 
A. Rising hCG, B. More Theca lutein cysts, C. Increase uterus size, D. Sub urethral nodule
D: Sub urethral nodule
Answer: D: Sub urethral nodule 
Explanation: Pre-disposing factors for development of choriocarcinoma after molar pregnancy - Rising hCG >100,000 Increased uterus size >6 cm Theca-lutein cysts * Sub urethral nodule indicates vaginal metastasis from choriocarcinoma ,it is not a predisposing factor. * Do not try to biopsy the sub urethral nodule it will result in torrential hemorrhage.