This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: AIIMS 2018, Subject name: Medicine
All of the following statements about insulin Afreeza are true except 
Select and explain. 
A. Inhalational preparation of insulin, B. Not a substitute of injectable insulin, C. Needs to be given in multiple doses, D. Used in combination with sho acting insulin
D: Used in combination with sho acting insulin
Answer: D: Used in combination with sho acting insulin 
Explanation: AFREEZA insulin : Inhalational preparation of insulin. Sho and fast acting insulin Used incombination with long acting insulin. Needs to be given in multiple dose. Should be used in combination with a long-acting insulin. S/E- Cough and throat irritation. It should not be used in individuals who smoke and COPD