This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Anaesthesia
Allergy in immediate perioperative period is due to: 
Select and explain. 
A. Opioids, B. LA agents, C. Induction agents, D. Neuromuscular blockers
D: Neuromuscular blockers
Answer: D: Neuromuscular blockers 
Explanation: Ans: D. Neuromuscular blockers(Ref: Miller 7/e p884)Most common cause of perioperative anaphylaxis is muscle relaxants and antibiotics followed by opioids and intravenous anesthesia.Most Common Drugs Involved in Perioperative AnaphylaxisSubstanceMost commonly associatedMuscle relaxantsSuccinylcholine, rocuronium,atracuriumdegNatural rubber latexLatex gloves, tourniquets, Foley cathetersAntibioticsPenicillin & other beta-lactamsdegHypnoticsPropofol, thiopentaldegColloidsDextran, gelatindegOpioidsMorphine, meperidinedegOther substancesParacetamol, aprotinin,chymopapain, protamine,bupivacaine