This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
Biopsy from an eight-year-old child with leg swelling showed smallround blue tumor cells consistent with diagnosis of Ewing's sarcoma. What will be the best method to detect translocation t(ll;22) in this malignancy? 
Select and explain. 
A. Conventional karyotyping, B. Next generation sequencing, C. FISH, D. PCR
C: FISH
Answer: C: FISH 
Explanation: Ans. C. FISHFISH is a molecular cytogenetic technique that uses fluorescent probes that bind to only those pas of the chromosome with a high degree of sequence complementarity.