This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Gynaecology & Obstetrics
Which of the following abnormalities can be diagnosed in the I st trimester of pregnancy? 
Select and explain. 
A. Anencephaly, B. Encephalocele, C. Meningocele, D. Microcephaly
A: Anencephaly
Answer: A: Anencephaly 
Explanation: Answer- A. Anencephaly"Anencephaly is diagnosed by the absence of cranial vault (calvarium) and telencephalon. Brain tissue is angiomatous.Early diagnosis is possible at aboat 13 weeks