This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: AIIMS 2019, Subject name: Surgery
Which of the following is true about prostate cancer? 
Select and explain. 
A. Histopathology is determined by Gleason score, B. Most common region involved is central zone, C. Most common type is squamous cell Carcinoma, D. It is not a hormone dependent cancer
A: Histopathology is determined by Gleason score
Answer: A: Histopathology is determined by Gleason score 
Explanation: Prostate cancer: Adenocarcinoma Malignancy arising from gland Hormone dependent malignancy PROSTATE Ca. BREAST Ca.| |TESTOSTERONE PROGESTERONE - M/C malignant tumor in ? > 65 years- M/C site for malignancy - Peripheral zone Grading (Pathologic): GLEASON GRADE PRIMARY (1-5) SECONDARY (1-5) Gleason Score: Primary + secondary grading= 2-10 Screening: | Levels of PSA (prostate specific Antigen)- not specific