This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: AIIMS 2019, Subject name: Microbiology
Which of the following marker persists in chronic hepatitis and recurrent hepatitis? 
Select and explain. 
A. IgG Anti HbcAg, B. HBsAg, C. IgG Anti HBsAG, D. Anti Hbs
A: IgG Anti HbcAg
Answer: A: IgG Anti HbcAg 
Explanation: Interpretation of common serological patterns in HBV infection Virus / Antibody markers Interpretation HBsAg HBeAg Anti - HBc Anti - HBs Anti - HBe + + IgM - - Acute HBV infection, highly infectious + + IgG - - Late/chronic HBV infection or carrier state: highly infectious + - IgG - +/- Late /chronic HBV infection or carrier state; low infectivity - +/- IgM - +/- Seen rarely in early acute HBV infection; infectious - - IgG +/- +/- Remote HBV infection; infectivity nil or very low - - - + - Immunity following HBV vaccine