This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: AIIMS 2018, Subject name: Pharmacology
All of the following drugs require dose reduction in renal failure except? 
Select and explain. 
A. Amphotericin B, B. Vancomycin, C. Gentamicin, D. Doxycycline
D: Doxycycline
Answer: D: Doxycycline 
Explanation: Those drugs which are secreted in bile do not require dose reduction in renal disease. Doxycycline is secreted in bile, so it is safe in renal failure Drugs (commonly asked) safe in renal diseases include: Safe (Cef): Cefoperazone, Ceftriaxone In The: Tigecycline R: Rifampicin E: Erythromycin N: Nafcillin A: Ampicillin L: Lincosamides (Clindamycin) Disease: Doxycycline