This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Dental
Which one of the following is not an Indication for antibiotic therapy In patients with acute abscess? 
Select and explain. 
A. Fever, B. Deep inaccessible pocket, C. Horizontal bone loss, D. Regional lymphadenopathy
C: Horizontal bone loss
Answer: C: Horizontal bone loss 
Explanation: None