This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
Chloroquine related eye disease risk is 
Select and explain. 
A. HIV protease, B. HIV reverse transcriptase, C. HIV integrase, D. HIV entry into the cell
B: HIV reverse transcriptase
Answer: B: HIV reverse transcriptase 
Explanation: Answer: . B. HIV reverse transcriptase >2 years (Ref Goodman and Gilman 12/e p14051Chloroquine related eye disease risk is high if duration of treatment is more than 5 yearsHigh Risk for Chloroquine Age >60 yearsdegDuration of treatment >5 yearsdegDaily dose >6.5 mg/kg/day of3.0 mg/kg/day of High body fatdegLiver diseasedegRenal diseasedegConcomitant retinal diseasedeg