This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: AIIMS 2019, Subject name: Gynaecology & Obstetrics
Hormone Replacement therapy is not indicated in: 
Select and explain. 
A. Hot flashes, B. Prevention of CAD, C. Osteoporosis, D. Vaginal atrophy
B: Prevention of CAD
Answer: B: Prevention of CAD 
Explanation: H indicated in menopausal women to overcome the sho term and long term consequences of estrogen deficiency. Indications of hormone replacement therapy in a menopausal woman Relief of vasomotor symptoms: hot flushes Prevention and treatment of osteoporosis Urogenital atrophy Premature Menopause Hormone Replacement Therapy is NOT indicated for prevention or treatment of cardiovascular disease. Natural estrogens produced in the body till menopause are cardioprotective, however Hormone Replacement Therapy (containing exogenous estrogens and progesterones)is not cardioprotective, n fact it is detrimental to hea when used for long term.