This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
A 22-year-old female gives the history of recurrent joint pains. She has now developed petechial hemorrhages. She is most likely to have: 
Select and explain. 
A. Megakaryocytic thrombocytopenia, B. Amegakaryocytic thrombocytopenia, C. Platelet function defects, D. Acquired factor VIII inhibitors
D: Acquired factor VIII inhibitors
Answer: D: Acquired factor VIII inhibitors 
Explanation: Answer:. d. Acquired factor VIII inhibitors (Wintrobes p1442-144-.'74;Harrison19/ep734-735, 740, 18/e p982).The clinical presentation in a young female of recurrent joint pains with petechial hemorrhage is suggestive of an autoimmune disease.A female patient is unlike to have hemophilia, as it is an X-linked disorder. However, she can have autoantibodies against factor VIII.