This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: AIIMS 2018, Subject name: Pharmacology
Major aim of phase 1 clinical trials is: 
Select and explain. 
A. Safety, B. Efficacy, C. Dose, D. Pharmacokinetics
C: Dose
Answer: C: Dose 
Explanation: Phase 1 clinical trial : It is first phase in humans. It is conducted mainly on healthy volunteers. In drugs with serious adverse effects and where alternative treatment is not available, phase 1 can be conducted on patients also. Major aim is to know the maximum tolerable dose (MTD). The aim of phase 1 trials should be marked as MTD > Dose > Pharmacokinetics > Safety