This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pediatrics
A neonate is being investigated for jaundice. A liver biopsy shows features of a "Giant Cell/Neonatal hepatitis". Which one of the following conditions usually results in this case – 
Select and explain. 
A. Congenital hepatic fibrosis, B. Hemochromatosis, C. Alpha–1–antitrypsin deficiency, D. Glycogen storage disease Type 1
C: Alpha–1–antitrypsin deficiency
Answer: C: Alpha–1–antitrypsin deficiency 
Explanation: Other conditions which also presents with similar clinical and histological features (i.e., with giant cells)
a)   ai antitrypsin deficiency 
b) Alagille syndrome                   
c) Niemann - Pick type C disease (NPC).
d)   Viral infections                         
e) Byler disease                    
f) Progressive familial intrahepatic cholestasis (PFIC).