This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Biochemistry
Which of the following is not required for protein synthesis of eukaryotes: 
Select and explain. 
A. RNA polymerase, B. Ribosomes, C. Peptidyl transferase, D. Amino acyl tRNA synthetase
A: RNA polymerase
Answer: A: RNA polymerase 
Explanation: Ans. a. RNA polymerase (Ref Harper 28/e p362) RNA polymerase enzyme is involved in transcription process, not in translation.The a-amino group of the new aminoacyl-tRNA in the A site carries out a nucleophilic attach on the esterified carboxyl group of the peptidyl-tRNA occupying the P site (peptidyl or polypeptide site).Peptidyl transferase: Catalyses two reactions, peptide bond formation between amino acids and together with release factor, peptide release.