This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Medicine
Acromegaly occurs: 
Select and explain. 
A. Before closure of epiphyses of long bones, B. After closure of epiphyses of long bones, C. Not related to closure of epiphyses of long bones, D. Depending on functioning on posterior Pituitary gland
B: After closure of epiphyses of long bones
Answer: B: After closure of epiphyses of long bones 
Explanation: None