This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Gynaecology & Obstetrics
What is the approved dose of misoprostol in emergent management of postpaum hemorrhage? 
Select and explain. 
A. 200 mcg, B. 400 mcg, C. 600 mcg, D. 1000 mcg
C: 600 mcg
Answer: C: 600 mcg 
Explanation: Ans: C. 600 mcg(Ref Williams 24/e p785)Approved dose of misoprostol in emergent management of postpaum hemorrhage = 600 pg.Misoprostol:Derman (2006) compared a 600 pg oral dose given at delivery against placebo.Drug decreased hemorrhage incidence from 12 to 6 percent & severe hemorrhage from 1.2 to 0.2 percent.