This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: AIIMS 2019, Subject name: Anaesthesia
Purpose of giving Glycopyrrolate before GA 
Select and explain. 
A. Decrease laryngeal secretions, B. Muscle relaxation, C. Prevents aspiration, D. Provides analgesia
A: Decrease laryngeal secretions
Answer: A: Decrease laryngeal secretions 
Explanation: Glycopyrolate in preanesthetic medication: Glycopyrolate unlike atropine and scopolamine, it is a quaternary ammonium compound, it doesn't crosses the blood brain barrier. It's role: To decrease salivary, tracheobronchial secretions. It can be use IV/IM It's anti-sialogue activity is best when given at 0.004mg/kg BW IM 30-60 minutes prior peak effects. Tachycardiac effects of glycopyrrolate are minimize when given IM. Decrease the gastric secretion and increases PH of gastric content. To counteract parasympathetic overdrive, dose: 0.1 IV, repeat every 3-5 minute. To counteract parasympathetic effect, atropine is preferred due to much faster onset.