This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Physiology
Best index to measure cardiac afterload is: 
Select and explain. 
A. Mean aerial pressure, B. LV end diastolic pressure, C. LV mean systolic pressure, D. Total peripheral resistance
D: Total peripheral resistance
Answer: D: Total peripheral resistance 
Explanation: Ans: D. Total peripheral resistance(Ref: Ganong 25Ie p544, 24/e p546)Cardiac output depends on both preload & afterload.The preload is defined by the venous return & left ventricular end-diastolic volume while the afterload is defined by the mean aerial pressure, which then fither depends on total peripheral resistance.