generate questions: In 1952 researchers at Ciba discovered the first orally available vasodilator, hydralazine. A major shortcoming of hydralazine monotherapy was that it lost its effectiveness over time (tachyphylaxis). In the mid-1950s Karl H. Beyer, James M. Sprague, John E. Baer, and Frederick C. Novello of Merck and Co. discovered and developed chlorothiazide, which remains the most widely used antihypertensive drug today. This development was associated with a substantial decline in the mortality rate among people with hypertension. The inventors were recognized by a Public Health Lasker Award in 1975 for "the saving of untold thousands of lives and the alleviation of the suffering of millions of victims of hypertension".
Who discovered Hydralazine? {sep_token} Why were the researchers recognized in 1975? {sep_token} Who developed Chlorothiazide? {sep_token} What is  Chlorothiazide used to treat? {sep_token} What was the main shortcoming in the drug Hydralazine? {sep_token} What was the name of the first oral vasodilator? {sep_token} What is the most used antihypertensive drug today? {sep_token} Beyer, Sprague, Baer, and Novello received what award in 1975? {sep_token} In what year was hydralazine discovered? {sep_token} Chlorothiazide helped reduce the mortality rate among those with what disease? {sep_token}