OnabotulinumtoxinA
"I was diagnosed with status migrainosis in November 2016. I tried an SNRI anti-depressant and have had two rounds of Botox. I can say neither have been effective. The only effect from Botox I've noticed has been the tight band around my head in the first dose of shots and then increased soreness in neck and shoulders in second lot. And I had to skip out of work yesterday because my eyeball and side of head hurt so freakin' much - two weeks out from the second round of Botox treatment. I do not recommend. My migraines are likely hormonal in nature and I have epilepsy. While that is controlled, it leaves me with few options. Loathe to try anti-convulsants as it might muck up my brain in worse ways. Yes, there are worse states to be in."