Sodium oxybate
"Just started my 6th month of Xyrem and not sure it is doing anything except keeping me awake every other night, giving me the munchies, waking me up (if I slept) freezing and decreasing the effectiveness of my Adderall up to 60mg 2xday, was taking 1/2 that prior to starting.  1st 2 months complete exhaustion, facial pain, sinus pain and just miserable."