Ezetimibe
"I have beeen on medicine for Familial Heterozygous High cholesterol for 15 years, Rosuvastatin half the max dose 20mg cut total cholesterol from 9.9 uk measuring system to 5.2, with no noticeable side effects.  Ezetimibe reduced this by 0.6 to 4.6 monitored quarterly, side effects first diarrhoea got worse and next resembled irritable bowel symptoms and then became like having severe gastroenteritis once a fortnight with in the last 3 days worsening nausea and delayed stomach emptying for up to 24 hours followed by 2 days of extremely frequent and exhausting vomiting and diarrhoea until only clear fluid was expelled followed by 3 days recovery starting a new cycle. I endured this for 18 months with various -ve tests. Stopping ezetimibe cured these side effects completely."