Sulfamethoxazole / trimethoprim
"Had bloody urine, started this drug for bacterial infection, day 2 on drug. I take Kefir  (yoghurt drink probiotic) and also a supplement called D-Mannose to help clear out bacteria from urinary tract. Can not take Cipro (tendon and joint pain lasting a year after) and allergic to many antibiotics. Having problem urinating now, 3 days to go.  I have fewer side effects taking probiotics during and months after. New reports say women need lower doses of all meds, and over 60 need lower doses. As female over 60 would have broken pills in half (without doctor's ok) but could not get them to break.  Urine has cleared up already - usually call pharmacist for info on problems."