Sertraline
"I had situational depression and was started on 50mg of Zoloft. It helped within a few weeks, but I had some major diarrhea when I started which seemed to start resolving itself, then I was upped to 75 mg and the diarrhea started again. It's been 10 months in total, and I still have episodes of diarrhea a few times a day for a few days. Then for a day or two I will be fine. I've lost about 19 pounds due to the appetite suppression effects and the diarrhea. I've also noticed a loss of libido but these are side effects I'm willing to live with as opposed to the depression. I am having my recommended at age 50 for screening purposes colonoscopy soon and am sure the diarrhea is not a cause for concern. We will find out."