Lasix
"I took the first dose on a Friday after work.  That night I was awake all night with terrible leg cramps and an odd cramp in my midriff.  I took the second dose earlier in the afternoon the next day.  The cramp in my midriff returned.  I called the hospital where my doctor practices and the nurse practitioner from her office called me back.  She advised me not to take the Lasix anymore and to go to the ER if the cramping came back tonight.  My ankle is nearly normal size, but I am not sure it was worth it."