Prednisone
"My experience was okay, I took 10 mg prednisone for about two weeks when I started taking isotretinoin for my severe acne. It reduced my inflammation very well, but caused uncomfortable bloating and very mild muscle soreness. It also caused me to have significant mood swings from having a lot of energy and excitement to being very depressed and having suicidal thoughts, and in some cases it made me a tad bit aggressive. So, it did the job well but the mental effects were kinda unenjoyable in my opinion. Personally, I won't say the drug is bad but I do highly advise you to take caution and monitor the mental health of whoever is taking the medicine."