Fentanyl
"I finally agreed to a long acting medicine to supplement my oxycodone. To make a long story short, on the 3rd day of wearing the 25mcg patch, I woke up with the most debilitating migraine I've ever experienced in my life. I called the doctor to notify him that I'd be discontinuing the medication. I didn't notice any significant change in my pain over the 3 days, and I'm too terrified of experiencing another migraine like that! (Jealous of all those that had great outcomes from using this medicine!)"