Prochlorperazine
"I was given Compazine during in-patient chemo treatment in 1999 (as a cheaper anti-nausea med., as I was on Medicaid).  The Drs. said it 'may' cause agitation/work poorly for younger people (I was 25 at the time).  The agitation & horrible feelings were immediate.  It got so bad I ended up just twitching, crying & moaning into my pillow.   My skin was crawling, I was flooded with anxiety/panic.  I COULD NOT lay/sit still.   Next chemo treatment  was the same, so I never asked for/took it again.  I'd rather have gone without anti-nausea meds than go thru that again.  I later found one of the night Drs. who was sympathetic & I got samples of the good (modern) anti-nausea meds.  No akathisia at all."