Spironolactone
"I had moderate to severe acne starting around the age of 15/16, right around when I got my first period. By age 20 my skin still wasn't clear, even on Yaz. That medication did wonders for my endometriosis and cramps, but my skin didn't get better. I talked to my doctor about spiro and we agreed that it was a good plan. 100mg/day for the first month, then down to 50mg/day. The idea was to "shock my system" for a big clearing. That first month was TERRIBLE. I broke out like never before with massive cystic, painful zits. My self esteem was worse than ever. BUT, I stuck with it. Today I'm on my 6th month of spiro and I LOVE it. I sometimes get a zit here or there, but nothing like before-- mostly just blackheads. My skin is even and clear!"