Levsin SL
"I just found out that this drug is "unapproved" by the FDA because it is "not effective".  However, in my experience, it is the most effective drug I've tried for my IBS.  I'm taking Linzess and use fiber supplements to regulate my system.  These have helped to limit the number of attacks; however, I do still have them about twice a month.  When my symptoms start, without Levsin SL I am in agony for anywhere from 45 minutes to two hours; with the Levsin SL, my symptoms come to a dead stop within five minutes of taking it.  The plain (not sublingual) tablets take a little longer to work, but they are still better than suffering for over an hour.  I don't understand how the FDA determined it was ineffective."