Phentermine / topiramate
"I started on this medication in October 2015 and I was at 320lbs - heaviest I've ever been. I am now 48lbs down, and I weigh in at the doctor's in 2 days hoping to achieve the 50lb mark.  Not only has this medication helped with the appetite control, it got me off soda!  I never thought that was possible.  It literally made the soda taste bad.  I couldn't believe it.  I have been addicted to full-on, regular soda for years. Now, I can't stand it and don't want it.  I have the tingling sensations but don't really have any other side effects.  I see the doctor once monthly and monitor my blood pressure weekly.  I am very, very happy with the results and plan on continuing until my doctor and I determine it is time to stop."