Metformin
"diagnosed at 15 (now 18) 5'3 ft 226lb. first I took 500 mg twice a day, plus I had spirolactone . no side effects. no weight change. acne was clearing up!!!  was on dance team and did ballet. wasn't that depressed.

recently (about 2 months) 5'3ft 230lb. 850 mg twice a day, no spirolactone. Acne came back (worse than ever), a little weight gain, more depressed, doing yoga now (quit dance team and ballet) no side effects.

and I have to take iron pills twice daily."