Spironolactone
"I am 22 and I have always had moderate acne on my forehead since I was 13. I first started with 100mg of spiro which caused a horrible initial breakout. I stopped taking it for 1 month and started it again but on 50mg and it really cleared my skin. Within one month I started getting a terrible headache that lasted 1 week it was so unbearable i stopped taking the pill for a week now and my headache is completely gone. I don't know if this happened because my diet consists of mostly salt food, but I was seriously scared I thought I had a brain tumor. This pill is a diuretic so maybe it'll work well to those whom have a well balanced diet, but as soon as you feel side effects you should stop it immediately!!! :("