Methylnaltrexone
"I have been on opioids for 29 years now. About 10 years ago, my doses were so high and the constant pushing because of impact ion unless I was taking 10 laxatives at night to wake up with unbearable cramps to have diarrhea, then taking more laxatives throughout day cured the fecal impaction....but I ended up with a external prolapsed bowel that would come out even going tinkle. The doctors had never seen one completely outside, which I would have to manually push back in every time. Surgery was 10 nights in the hospital on one of those automatic beds that move position so you don't get bed sores. 1000+ stitches and staples and now Relistor....doesnt always work, but when it does....OMG! It feels like heaven...Yeah!!!!"