Atovaquone / proguanil
"Malarone is as safe as you can get. I have used it for 12 months without any symptom at all from the medicine or the parasite. My wife has taken it for 7 months and likewise no problem at all. The best part, while 12 colleagues have fallen and become hospitalized with the prevailing malaria in West Africa they were not taking any anti-malarial."