Fluoxetine
"I didn't want to take hormones for hot flashes but the hot flashes were bad enough that I was going to try hormone therapy anyway. My family doctor suggested fluoxetine or Prozac for hot flashes. I had never heard of taking an antidepressant for hot flashes before so I studied before saying yes. It started working after just a few days. I have occasional hot flashes that are milder than before an way way less frequent. 20 mg is the dose that works for me. I tried reducing to 10 mg for a few months but it didn't work as well as the 20 mg. I have been on this for 16 months now. On the flip side it has also helped with some anxiety issues I didn't realize I was experiencing. : )"