Spironolactone
"GIVE THIS MEDICATION TIME TO WORK. I have been suffering with acne since I was 12 years old, and I am 39 now. I started spironolactone 8 weeks ago. I would say that the bumpiness in my skin improved within the first week. But the breakout during the 2nd week and the residual mess during week 3 had me wearing turtlenecks. But after that, I saw nothing but improvement. Less and less acne, skin smoothing out, less oiliness. Now I am about 95% clear and I only expect it to get even better!"