Linaclotide
"I have suffered chronic constipation for over 15 years, no physical reason for it, my bowel just doesn't work and it gets worse around the time of the month.

I have tried everything the doctor could prescribe and nothing worked, resolor helped a little but only for a short time and I was having too much time off work in agony.

I have been taking linaclotide every day for about a year and I love it! Every morning 1/2 an hour before breakfast then bm 1/2 an hour later. I do sometimes have the diarrhea and it is hideous but no pain so I don't care! No more passing out on the loo in agony. It took a while to settle but I say give it a chance and I sometimes add movicol if I'm feeling like things are slowing, it eases everything along."