Minocycline
"I have had acne since my teens- I am 36 now and I still would have it, if I didn't take Minocycline.  I started off on 100 mg a day (50 mg twice daily) and now I am down to 50 mg once a day.  I hated my acne.  It is almost completely gone (I still get a few but not many at all) and it's so worth it. I haven't had any noticeable side effects.  Plus with my insurance it's so much cheaper than all the skin stuff I tried that never worked. 
WARNING: If you are thinking about getting pregnant, get off this medicine (talk to your Dr) because it is proven to be harmful to the fetus."