Vortioxetine
"This medication has been a miracle worker for me. I tried 15, yes 15 different medications ranging from SSRIs, SNRIs, mood stabilizers, and tricyclics ... This is the only one that has worked for me. It basically "turns everything down" for me. I have horrendous anxiety that causes my depression, so the dampening is a huge relief. I had nausea and other digestive issues for about a week, but those subsided. I've been on this medication twice now: I stopped when I wished to become pregnant and restarted after my daughter was born."