Quetiapine
"Seroquel is the only medication that has really worked for me. I have major depression and possible bipolar disorder and it’s helped lessen my degree of depression and help me get on a more steady path. Psychotic symptoms are under control. I thought I had treatment resistant depression for a long time until I tried this. The only problem is the sedation. I’m on XR and I don’t have the sedation as bad."