Lurasidone
"I have some kind of Depressive Disorder-- Never have had a diagnosis done but I ruminate a lot. I also suffered a manic episode a few months ago which served to make me feel more trapped and hopeless than ever. I started Latuda about 6 weeks ago at 20 mg. My psych was confident about this medication. Three weeks into the treatment I began to feel way less depressed. I was socializing more, and I wouldn't get stuck in my thoughts. It was wonderful. Unfortunately it lasted only for a few days and the depression came back. I continued to work with my doctor and we increased the dosage from 40 to 60 to 80. Right now, I am tapering off of it and feeling more miserable and incapacitated than I have in my entire life. It's horrible. I feel like I don't know what to do with myself. The voice in my head is relentless.

This medication made me worse, and my psych and I had very high hopes for it. I couldn't sleep on it as well. I wanted to stick it out to see if a higher does would work for me but decided that the depression I'm experiencing now is much too intense to push on through. I'm going to see her ASAP after the holidays and ask to be put on Lactimal. Maybe this will work for you, but it was not my niche. I'm giving it a two only because I experienced no side effects aside from the insomnia, and Seroquel took care of that."