Lithium
"I was diagnosed with bipolar disorder about 3 years ago during a hospitalization. Was put on 600mg Seroquel and 200mg Lamictal. Switched doctors and they decided to replace my medicines with lithium. I don't know why but it made my condition 10 times worse and I got very sick.  Fever, vomiting, nausea, drowsiness, fatigue, excessive thirst and urination. Plus it makes my mood swings much worse and shortened my patience and turned my depression to rage. Gave uncontrollable twitches and body movements and shaky hands. Though I have been off it for a year. My case is probably an anomaly as it seems to work wonders for everyone else. "