Desvenlafaxine
"I've been suffering from major depression & anxiety for the past few years until I finally decided I've had enough! Initially I was prescribed Cipralex which helped with my anxiety but I gained way too much weight & couldn't stop eating so after approx 6 months I went off it which wasn't hard at all, no withdrawal symptoms. 
I was then put on Wellbutrin 150mg then after approx 1 month up to 300mg. I felt great positive energy   lost a lot of the weight I gained. After approx 1 year I felt that this med was totally ineffective & I wasn't feeling anything. 
My doc then prescribed Cymbalta which appeared to work well for approx 1 month then after the next 2 months I didn't feel anything.
Now I'm on Pristiq for just over 5 weeks, I feel good."