Linaclotide
"I've been taking Linzess a little over a month now for chronic constipation. I used to have a bowel movement about twice a month. And it was like that for at least 10 years. I was taking Miralax and Phillip's milk of magnesia and magnesium oxide daily.  Now I go almost everyday. I'm noticing a little water retention, but as long as it doesn't get bad I'm not worried about it. I gained soo much weight from not going to the bathroom and am now in the process of bariatric surgery. It should happen in about 4 more months. But I'm weighed regularly because of it and I am still losing weight like I'm supposed to. So as long as that continues I'll keep taking it for sure!"