Effexor
"I've been on Effexor 37.5mg once daily since September 2006 mainly to relieve symptoms of Irritable Bowel Syndrome & Depression. Effexor has worked great for both. I tried to get myself off of Effexor a few years ago & took St. John's Wort instead. I was lucky not to have any withdrawal symptoms. However, the depression returned, which I couldn't handle and returned to Effexor. I did wean myself off it and had no withdrawal symptoms. Experts say if you get off it, have to return to it, it may not work again. That didn't happen with me.  I just found that Effexor raised my blood pressure & cholesterol.  I have to decide whether to stay on it and be sane & preserve my kidneys, or stop it & get depressed AGAIN. Conundrum."