Xolair
"I have had CIU for over 13 years without remission.  Horrible, painful, debilitating hives that grow for days before receding. I've never gone more than a couple of days without at least one hive, despite mega-doses of antihistamines and other doctor recommended medications. I'd tried it all!  I received my first injection of Xolair 26 days ago and have not had one single hive! This medicine is, so far, the miracle I have been hoping and searching for, for 13 long years!"