Adalimumab
"I have been on Humira for 11 months now, and have seen no long term or overall improvement with my HS. During the first month where the dosage was very high (4x at week 0, 2x at week 2, week 4 starts the 1x a week dosage prescribed for HS) there was a noticeable improvement, but it quickly went away and my skin kept (and keeps) progressing while on Humira.
Injections in the tummy are much less painful than injections in the upper thighs, and leaving the pen out for 30-60 minutes before injecting probably helps (I have never injected without doing this, so I can't say either way). Injection site soreness, at least with me, is fairly minimal and goes away within a few hours.
I haven't really noticed any other side-effects at all."