Malarone
".Scariest drug reaction I have ever had.   Started with being awakened by difficulty breathing (middle of night).  took some antihistamines, and tried slow controlled breaths;  then used an inhaler.   Frequent urination (really frequent  with some leakage!).   

   By morning had sores in mouth from the swelling,  red tissues in mouth, swollen eyelids, lips and face.   Started a fever which went up to 103,  Then got big leopard spots all over (why not, in Africa?)

   a pharmacist in our group insisted this must be anything  but the Malarone because even he and his wife were taking it.!!!  Don't listen to people like that, almost continued to take it.  Horrible experience, quit it and did not get malaria which would have been preferable."