Desvenlafaxine
"I took Pristiq for years and it was wonderful.  Unfortunately my insurance changed and I wound up on Effexor, which caused me horrific night sweats.  When I saw Pristiq had a generic, I was thrilled!  Now that I'm on it, I realize it's not anywhere close to the brand name.  I feel terrible on it.  I have headaches, jaw pain, I have heartburn, and I've even noticed some heart palpitations.  I'm really disappointed in the generic, but I don't want to go back to Effexor and deal with the night sweats, so I'm kind of at a loss for what to do.  I'm hoping if I give the generic Pristiq more time, my system will adjust.  I feel for the rest of you are having issues, because it's not fun."