Testosterone
"48yr old on Testosterone Cypionate 200mg/ml 0.5cc injections every 10days for hypogonadism diagnosed back in 1999.  Tried Androderm for a month or so but broke me out in blisters and itchy. Been on this dosage for years. Problem last 3 days I feel fatigued and increased appetite, have been gaining weight yearly, now almost 50lbs but not muscle. Recent testing shows 9yrs older and 2 days after injection a result of 600 which should be much higher.  Also estrogen levels are now high. As men get older our bodies begin to convert more free testosterone to bound version DHT & into estrogen so this isn't a surprise now I've read about it.  "