Gabapentin
"Hi, I have suffered from CFS/ME for about 25yrs.  IBS-D started a short time after my viral infection.  I am also on antidpressants, muscle relaxants and pain killers.  I have been on loperimide, buscopan, and codiene phosphate with only temporary relief and my ibs-d could always override the drugs.My gut has become incredibly calm since taking 100mg of gaba in the morning and 100mg at night.  I am eating, in limited amounts, food that I couldnt eat prevoiusly without severe diarrhoea.  I was initially prescribed this drug for neuropathic pain and I am delighted to find it works for my gut too. I have read of other people with ibs improving since being on this med."