Clonidine
"I have had hot flashes for over 2 years with hot flashes that wake me up every hour. I haven't slept through the night in over a year. I was told to take one .025 at night and I could increase them if it didn't work. I took that dose for a week and I didn't feel anything; same old. I then tried a few nights taking 2 and still nothing. After reading the other comments I think I'm going to take 4 tonight and see if that works."