Bupropion / naltrexone
"In mid June 2015, I started leaning up my diet. I have PCOS and have been very overweight since I was a young adult, over 100lbs. So fast forward to June 2015, I'm now 38. I weighed 284lbs. Holy God! I'm only 5ft tall! 
 I started the Ketogenic or Ketosis diet. High fat, low carb= zero results. Then in August I saw the doc & started on Contrave 8/22/15. I lost 10lbs the 1st. Month. Sept-Oct was only 5lbs. It's gradual but w/PCOS, it's next to impossible. I use Scale Down. It can make you anxious weighing. My doc's big picture, even 5lbs/mo. is still a loss. There are long plateaus & weight gainin some days, but then you lose a couple lbs & it does work. I haven't had pasta/bread/soda/rice/chips/cookies/candy since June, no more addiction."