Medroxyprogesterone
"As far as birth control effectiveness goes, it does great. Never had any issues with that. However, the mood swings/anxiety/depression were TERRIBLE. And they've only gotten worse since I've gotten off of it. It's enough that it's severely effecting my outlook on life and my relationships with those around me. I've recently become active and notice it's easier for me to get hurt than it was before. (I assume that's because of the bone density loss..) I was on this for 9 mo/3 shot cycles and I never adjusted. It may work for you, but it did not for me. I'm going to try an IUD next and hope for better results. Fingers crossed."