Amitiza
"I have been constipated for the past 8 months following an injury that left me with two broken vertebrae.  Nothing seemed to help. Went to GI and they ordered a scope. Started me on Amitiza.  I had been taking Miralax and Ducolax as well as the occasional stimulant laxative.  The day I started on Amitiza I destroyed my bathroom. Very few side effects.  I take the 8mg dose. People that complain of bad side effects are probably taking the higher dose.  It's literally like the scene from 300 where the Spartan kicks the Persian in the chest and he falls down the well. It's like Amitiza is doing that but in my colon.  "