Nortriptyline
"I'm 33 have been taking 25mg for the past 4.5 years. I have been getting aura migraines since I was 13. They have always been unpredictable and could never pin down particular triggers. In my early 20s I took sandomigran for a couple years but found I gained too much weight and still got migraines. For the first 4 years -pretty much to the day, of taking nortriptyline I didn't have a single migraine, normal headaches lessened, my irritable bowel syndrome and endometriosis improved and then I got the dreaded aura and a terrible migraine. I have now had 3 migraines in the past 5 months and curious as to why it's not working as effectively as it used too. Side effects: no weight gain, I get a dry mouth all day, lowered libido, restless sleep."