Propofol
"After being diagnosed with Attenuated familial adenomatous polyposis (AFAP) (a genetic disease of the colon), I have had 6 colonoscopies, 5 with propofol and 1 with twilight sedation. By far, propofol is the best! You come out of it fast, and feel fine afterwards, whereas with twilight sedation I was out the rest of the day and was depressed afterwards. Strange feeling/mood from that. Propofol had no after effects. Wednesday having another colonoscopy with propofol! Yay!"