Chlordiazepoxide / clidinium
"This has been very effective in managing my symptoms of IBS-D. It helps with intestinal burning, gas, bloating and diarrhea, etc. I do still have to take Imodium at times. Side effects are not bothersome or have worn off.   I have been taking it regularly for years and if I forget to take a dose, my stomach (or intestines) remind me! It used to be very low cost which was great. Now it is getting more and more expensive. Medicare does not cover it. "