Propofol
"I put off my first colonoscopy for 15 years (mostly due to the barbaric prep) until today, and I'm glad. I had an endoscopy 30 years ago with IV Valium and it was a dreadful experience. I went in to this with extreme apprehension and the nurses kept telling me things have improved a lot. Wow! They were right! Propofol made it so much easier. I went to sleep, never had even a fuzzy hint of the procedure, and I was dressed and leaving 20 minutes after it was over. I'm so grateful."