Nitrofurantoin
"This is the worst I've felt without being called sick.  Headaches, neckache, fatigue, depression while I was taking it.  Stopped taking the medication half way through.  Now I'm on Cipro.  I will NEVER take this medication again.  Makes you wonder if there was a trial period before it was put on the market.  I'm usually tolerant of medication, and I know I have a high pain threshold, but this was something else.  Also makes me wonder about drug manufacturers, especially now with the presidential elections are fast approaching.   Most women are the ones experiencing UTI's, and most CEO's who are in charge of these big drug companies are men.  Go figure!"