Methylnaltrexone
"I just used Relistor for the first time. I have chronic abdominal pain that provides the wonderful need for strong narcotics. They are terrible on my system and possibly from the constipation or maybe a result of the many many surgeries I have been through I have very painful bowel movements. Its like I can feel the stool winding through my bowels and it feels like sharp rocks! After the injection I had almost instant cramps and only a moderate amount of gas. I felt the "winding rocks" moving with a vengeance. That's why I'm not giving this a 10 because of the cramps (which could possibly be issues with my system). Like another reviewer said..I had a massive movement 30mins later. NICE!"