Lithium
"I have  Bipolar Disorder, PTSD, Anxiety, OCD.  I Started taking 300 mg once at night, gradually went up to 1200 mg before my psychiatrist took me off of it. I've taken other mood stabilizers as well as antidepressants and antipsychotics with none really having a noticeable effect. It helped to mellow me out some, but during and after stressful life changes and traumatic events that occurred, my anxiety, mania, paranoia, anger, irritability, brain fog, etc. was full blown. My depression and brain fog always lingered throughout the whole time I took it as well. I did not want to risk upping my dosage due to the possible toxicity. I was starting to feel extremely nauseous after taking it even though I always took it with plenty of food and drank plenty of water."