Rytary
"My mom was switched to Rytary to decrease off periods.  She used to be able to walk one mile.   At first the Rytary seemed great, but then her neurologist couldn't get a dose that worked consistently.  The manufacturer says absorption is 70%, her Neuro says 50%, but sometimes it was 0% and when we would add some immediate release levodopa, she would get horrible dyskinesia.  She could barely walk and we've switched back to old meds with little improvement.  I regret ever switching!!"