Savella
"This is a tough one. I've been taking Savella for not quite a year. I have no known side effects, taking twice daily x 50mgs other than slight drying but I take other meds that also could be suspect. 
Here's my report. It mainly helped take the stiffness, pins and needles out of my knuckles in my hands for months BUT know that is coming back. I think my body is getting used to it and its not working any longer, at least not as well. My Doc and I talked about going to 100 mgs but have not. 
I still have to take Vicoprofen for my Fibromyalgia. Nothing else takes the overall tiredness and pain away like that. 
Even though its not my miracle drug I like it enough to pay my $45 monthly script for it."