Sumatriptan
"I've had migraines (about 4-6 times a month) since early puberty, and after a few hospital visits my mother finally took me to a specialist and got a sumatriptan prescription. It has greatly improved my quality of life. It kicks in after about 40 minutes for me (longer than advertised, but I'm on a small dosage due to my small frame). It does leave me feeling heavy and numb, and it has made me nauseated on occasion. It's uncomfortable, but much better than a migraine."