Pegfilgrastim
"After three Nulasta shots, three weeks apart, each one caused basically the same side effects which was severe pain.  After the second/third day, the pain started and it was the worst pain I have ever experienced in my lifetime.  In the bones and muscles.  I took Advil that seemed to take the edge off but didn't take it away. Tried tylenol and it was basically the same, not much help.  The severe pain lasted for about five days.  Even seven or eight days later, I  still had serious pain in the  bones but not as bad as the first five days."