Baclofen
"I take 10 mg at night for intense right leg spasms that were occurring every morning and sometimes multiple times per day. Very painful and debilitating. First week on Baclofen felt a bit drowsy at night, but that quickly subsided. It has almost entirely taken away the morning spasms, leg only feels a bit tight when it wants/needs to spasm. This medicine has changed my life! If I miss one dose, the spasms quickly return. I definitely recommend this to anyone with spasm pain."