Spironolactone
"I went off the birth control pill at age 38 (after being on for almost 20 years) and within 2 months my skin went crazy. I started experiencing bad cystic acne to the point I had no less than 10 bumps at once and was spending a lot of time and money at the dermatologist on injections. I had never had a cyst before--just typical teen acne breakouts in high school and college. It was painful and I felt embarrassed to go anywhere in public. My self esteem plummeted. After 3 months my dermatologist recommended spironolactone. I started at 200 mg and within a month my face was totally clear. After 6 months I went down to 150, then another 6 months down to 100, which is the dosage I still take 2 years later. Best medication ever!"