Doxycycline
"I have been on Doxycycline for at least 10 years straight for acne. I saw a big improvement in my skin when I first started taking the drug in my thirties. Now that I'm 48 and entering menopause, it seems to be a little less effective because of my hormonal changes probably. But I have never had any side effects with this drug, which is great considering the amount of time I have been using it."