Sertraline
"I was taking Lexapro 10mg then upped to 20mg for the past 5 years. In the beginning it was great, I felt great, no anxiety or depression.  But for the past two years my everyday life started to become a struggle. I became upset easily, I cried all the time, it was horrible.  So my Dr and I decided that maybe the Lexapro had pooped out and to try a different antidepressant. So I began sertraline 50mgs. I've had no side effects except for some heartburn right after taking. So I began Prilosec to counteract this. I feel good. No anxiety and I can feel my depression lifting. I sleep fine no problems there. But I do take 25mgs of Vistaril at night so I'm sure that helps. "