Januvia
"Doc put me on Metformin, which my liver didn't fair well with, and then tried the Januvia 100mg.  After 2.5 wks, I told him I was experiencing facial / hand / eye lid swelling and told him I felt this wasn't a good fit for me.  So, he prescribed Januvia 50mg, which after three days, caused nausea, upper abdominal pain, orange urine, and skyrocketing BG from low 120's to well over 200's after eating.  I immediately quit taking it."