Sulfasalazine
"After being on methotrexate and Humira I experienced no relief as well as a SEVERE LIFE THREATENING episode called Ludwigs Angina, ended up in a coma for 4 days, and was told if I had waited 1/2 hr longer to go to ER, I probably wouldn't have survived! I swore off all arthritic medicines for a year, except for pain medicines.  Rheumatologist understood, and after a year suggested we start back very passively as opposed to aggressively to treatment. She suggested SSZ (sulfasalazine) and I reluctantly agreed. I was told it could take up to 3-4 months before I would see any improvement. Within 3 weeks I felt like a new person, I've been on it for a year and feel wonderful!"