Linaclotide
"I've only been on this med about one week, but it worked immediately.  My intestinal motility was vastly improved, I had no cramps, stomach pains or discomfort.  The only side effects I've experience is diarrhea with some urgency, and a SLIGHT increase in gas but with no bloating.  I haven't taken any of the significant amount of laxatives I've had to take in the past, the Lizness is all I've had to take.  I'm hoping that overtime the urgency for the diarrhea will adjust (I don't mind the diarrhea itself, it's far preferable to the uncomfortable constipation!)"