Buprenorphine / naloxone
"Started with Percs, moved to straight oxy at 100-120mg/day. Never beyond that. Tried a half dozen times to go cold turkey.  Not much luck.  Closest I have ever gotten is with Sub.  Problem is that with Sub you are still just taking opiates in a slightly different form.  That's why it "works so well."  The problem comes when you stop the Sub. The hardest jump is from some opiates to NO opiates. No matter what, you're going to experience withdrawal.  You have to pay the piper at some point, even though some methods (like a taper) might make it a little easier.  Anyone who says that withdrawal is just a weekend on the couch is selling you a bill of goods (or, is the doctor encouraging you to take the pills). Be prepared for 10 days."