Estradiol
"I've been Vivelle for at least 4 years now. HRT pills upset my stomach and were not as effective for me. I tried the generic version of Vivelle but it was a much larger patch and did not stick as well. The adhesive on the generic also gave me a rash. Stick to the brand on this one would be my recommendation. I'm down to the lowest dose, hopefully will be done completely in another year or so. But this has saved my sanity and that of those around me."