Acetaminophen / dichloralphenazone / isometheptene mucate
"Like previous reviewers, I find the Midrin substitute hit-or-miss. Taking Midrin early or late in the headache seems not to matter; sometimes it works, sometimes it doesn't. I took Midrin in the early 80s, and it worked every time, and fast. (the effect was as if my head just floated away, but I could still function). With the Midrin substitutes, the headache just slowly subsides. Either the formula is different or I am, but it's not the product it used to be. Still, it's the only thing that comes close to working for me."