Ustekinumab
"Wow. I have tried every medication from 6mp methotrexate humira infliximab vedolizumab etc.  all failed in the end and my latest try vedolizumab didn't work at all.

I was in a flare for 8 months my Consultant said the only option left was to remove my colon.  I have never been in so much pain and weight loss.  Then I got a call from the hospital saying the drug company was willing to offer me ustekinumab. It's not licensed in the UK yet for crohns so I wasn't sure.

But omg within 9 days of treatment  I've never felt so good .  I must admit in those 9 days when I never felt anything I thought it wasn't going to work then boom I woke up one day and felt amazing.   If you get offered this amazing drug just give it time and it will work wonders"