Naproxen / sumatriptan
"Just wow. I frequently suffer from migraines and excedrin usually does the trick. Every so often I'll get these headaches that last for days and excedrin won't work. My doctor prescribed me Treximet and what a difference. I like this drug because if you don't take it at the beginning of a migraine it STILL works. I had a migraine for 24 hours+ and took one this morning. Within 30 min it was fading and in an hour it was gone. The first time I took Treximet I did have the neck stiffness and fatigue, but the second time no side effects except a dry mouth and heavy feeling in legs that passed quickly. So worth not having to deal with a headache that can really ruin your whole day and just make you want to lie in a cool dark room. Love Treximet."