Senna
"I take opiate pain relievers, but if I do some walking, I usually don't have a problem.  When I stay in the house too long I get constipated pretty badly. It's been about 8 months since I've taken any Sennakot, so, I figured it would work. The ones I'm taking are 8.6mg and I've found in the past that if I only take 2 or 3, nothing happens. I found that I need 5 or 6. Sometimes I would get some bad stomach pain, but it was a small price to pay to get some relief.Twice this week I've taken 6 before bed (8am), but nothing happened. The second time while getting up to use the bathroom, I felt it working and went back to sleep, but when I got up an hour later, nothing. Anybody else have this happen?  Maybe I sleep past my opportunity."