Tramadol
"Been using naproxen almost daily for years, for back and hand related near chronic pain-partially due to inflammation and swelling.  Had to stop taking ALL NSAID's on orders from my GI Dr. 

USED 3,000mg daily ACETAMENOPHEN FOR 3 MONTHS-much less effective than min dose naproxen had been for pain and useless for inflammation/swelling  (using large doses of omega 3/fish oil for inflammation.)

Started tramadol about 2 weeks ago, noticed difference over acetamenophen alone in the first 2 days while taking 25mg at a time and still ramping up to 4x daily.  Now I take it every 6 hours, and if I miss a dose-especially the last one at night-significant pain and stiffness returns. Hope to switch to extended release version."