Pramipexole
"I was on mirapex for RLS for about 11 years.  At first it RLScgot much worse.  I had uncontrolled arm and leg movement when relaxed or sleeping.  I did not get sleep.  Finally went to a neurologist.  He started me on 300mg of Gabapentin and worked up to 1200mg at night and 300mg at morning and afternoon.  Then I started to reduce mirapex.  I went through severe withdrawal for 5 days and moderate for another 5 days.  I now can sleep and the uncontrolled movement is minimal.  My neurologist said that mirapex was the cause of my worsening condition"