Morphine
"I've been on Kadian for 8 months (car accident 3 years ago, suffering from extensive postural and disc and recently diagnosed PTVS symptoms since). I'm 22 and started feeling able to live my life again after taking Kadian (10mg 2 x day) and it seemed to make my mood better. It no longer works at current dose and doctor won't move up a dose, and doesn't believe in short-acting medicines. First 6 months it really did wonders and gave me a lot of my life back. Constipation is brutal with this medicine - I take Miralax daily with some relief. Withdrawals are horrific."