Evolocumab
"I have inherited familial high cholesterol. At age 36, I had quintuple by-pass surgery. At age 46, 56, 63 and 65, I had stents due to blockages. I've been taking statins for 30 years in spite of severe muscle pain, currently Crestor and started Rapatha injections every two weeks,  shortly after it became available. I consider the shortness of breath I have been experiencing to the Rapatha, and my symptoms have grown increasingly worse during this period of time, including weakness and trouble breathing. I have  allergies and asthma, which I thought was the source of my trouble breathing, however,  my breathing problems have significantly worsened since taking  Rapatha and is a debilitating side effect. Cholesterol  has dropped significantly."