Trintellix
"I was on Lexapro for about 2 years until  itstopped working. Prior to that,over the last 25 years was always on an antidepressant. You name it, I've tried it. What the antidepressants  did for me was just take away the severe irritability that I had, I was really at a low point when my doctor asked me to try Brintellix. I had no desire to do anything.  I felt no joy. I had been taking 40 mg.of Lexapro a day. Doc said I didn't have to wean off it.  He said I could just switch, starting the next day and I did. I Started on 5mg for the first 2 wks then increased to 10mg it's only been 4wks that I have been on it and my nausea has got better, I have a clarity in thinking that I didn't have before. I feel joy now. I am staying on it.  Also, no sexual problems on it. Got Hope!"