Bupropion / naltrexone
"I've been on Contrave for just over 6 months. I've lost 50 lbs. I am incredibly grateful I found this drug.

The side effects for the first several weeks were pretty rough, I admit. The two worst were nausea and a tremor. They continued for roughly a month - but then they stopped. I still deal with constipation, but that's easy to manage.

In addition to the weight loss, I have kicked a lifelong sugar habit. Even my family members were stunned by that, as I was a serious chocoholic.

Now that I've reached my goal, my doctor and I agreed that I should remain on the drug for 6 more months, and then taper (which is standard protocol for going off antidepressants like bupropion).

Contrave is pricey, but for me, it's been worth it.  your mileage may vary (YMMV)"