Methadone
"I am prescribed 1-2 (10mg) tabs of Methadone, up to 6 times every 24 hours. On the "good" days, I take a lower dose (like 3 (10mg) tabs in 24 hours) with pretty much complete relief & on the "worst" of days, the max dose (12 (10mg) tabs in 24 hours) makes doing the everyday "necessities" actually possible. The biggest negative I've experienced while on this medicine, is a MAJOR WEIGHT GAIN of around 1-2 lbs a WEEK (So like 40lbs in 6 months, before I started working out & dieting to compensate)! Also, this medication has COMPLETELY STOPPED my menstrual cycle! However with these downsides, I'd still strongly suggest this medicine for those with chronic severe back pain!"