Vortioxetine
"Started this medication 5 days ago after 3 years on Sertraline. Severe stomach cramps to the point I can't stand up which lasts all day.  I have severe bowel movements, skin itchy, headaches, feel sick all the time.  It's too early to say if it has helped my mood as I am only on 5 mg at the minute and will move up to 10mg in 3 days. I am hoping these side effects will pass soon as very hard to cope with. If you have a low pain threshold I would not take this medication, but if you are determined to feel better in the long run I would give it a try. Will update in next few days."