Bupropion / naltrexone
"I've been on this medication for 3 and a 1/2 weeks. I started at 309 lbs and today I'm at 295.4, so as of today I've dropped 13 pounds. I have drastically changed my diet to about 600 calories during the work day and up to 1000 at night.  It may sound weird but I'm a construction foreman and stay very busy and therefore can eat low cal snacks and a simple lunch and be fine. I also do a lot of walking around and going up stairs. (100 at a time). I also take plenty of fiber every night.  Without the medication I was constantly hungry and sustaining my weight (not burning fat). As far as taking 4 pills a day I've taken ssri's for years, nuff said."