Hyaluronan
"I got diagnosed with chondromalacia in both knees 7 years ago. Fast forward to the present, it's now osteoarthritis in both knees and clearly visible on xray. I got the Orthovisc shots for the first time this month. The shots are rather unpleasant, sure, but they are totally worth it. Your knees will be rather sore for the next 24 hours, but it's tolerable. I'm extremely pleased with the results. I had been taking Voltaren for a few years, and that only alleviated the worst of the symptoms. The stiffness from sitting long periods or waking up in the morning is almost completely gone. Stairs no longer hurt. I still have to ice my knees and experience some stiffness after workouts. Nothing will bring my old knees back, I guess."