Tamoxifen
"I started taking this medicine after abnormal mammogram and biopsy found precancerous cells.  I have really bad hot flashes several times a month, some joint and leg pain.  My menstrual cycle is regular but I experience nose bleeds the week before.  My hair started to thin about 3 months after starting this medication, that has pretty much subsided and I am going on one year now.  I do get a little more irritable than usual but all in all things are pretty manageable now.  So only 4 years to go!"