Trintellix
"I'm taking 300 mg Bupropion and still extremely depressed.  Psychiatrist gave me a month of 5mg samples of Brintellix to supplement the Bupropion.  I have been taking it for 5 days now and have severe nausea & vomiting along with constipation. Nausea & vomiting occurs 20 min. to 1/2 hour after taking so the drug isn't absorbed into my system to have an effect on my depression.  I am on other medications that I was taking at the same time as the Brintellix.  I've decided to take the Bintellix with food in the morning and all other meds at night due to the vomiting so that the other drugs can be effective.  I can deal with nausea & constipation, but the not vomiting. I will continue taking and hope the vomiting stops. Fingers crossed."