Lithium
"When I originally got sick with insomnia and mania, I was prescribed Seroquel. 5 years later was admitted to the hospital and a student doc suggested I try lithium. 

It kills fast onset mania quickly and fortunately have minor ill effects from it. Lost precision hand eye coordination for playing sports like baseball, that's the only issue I have had with it. And minor sun sensitivity.

Its also good being a natural substance on the table of elements so it's not a synthetic medicine.  

Very lucky to be on a low level that works so no need for constant blood monitoring."