Tramadol
"Like many of the reviewers here I discovered the benefits of the medicine for depression by accident. It had been prescribed for back pain after I hurt by back lifting a heavy bag out of the car trunk at the airport. Yes, it helped in a with the back pain from 
the injury but it totally destroyed my depression immediately. It works in less than 1 hour and you will feel uplifted and hopeful .If you suffer from depression talk with your Dr.  about Tramadol. Plain and simple...it works and works fast. No kidding this is a depression killer."