Bupropion / naltrexone
"Unless you are extremely obese (>350 pounds) and have no other options avoid this medication at all costs. Side effects for me were severe nausea, vomiting constantly, heart palpitations (which have not gone away even after stopping the medicine), chills, terrible body aches, delusions, fatigue, insomnia, bizarre dreams, and apathy. Even after stopping the medicine I can still feel after effects. This drug needs to be investigated for safety cause someone I know also had close to the same side effects as me. I did lose 2 pounds the first week but I believe it was cause I had no desire to eat and the constant vomiting. It's also very expensive."