Diclofenac / misoprostol
"I have been taking this medication for well over a year now and I am totally satisfied. It has made my arthritis bearable. Even though my prescription allows me to take 2 a day, so far I have only taken 1 before bed time.  I am nearly 76 years old. My husband who is 65 started taking the same medication but he takes at least 2 every day.  He also has 2 slipped discs from a back injury along with the arthritis."