Fluticasone / salmeterol
"I don't know about others, but this is a god send to me.  I have very, very bad asthma. Walking up a few stairs can wind me, as can walks (which I love doing), and exercising is extremely difficult. The pains from asthma problems can hurt quite a bit. I got on Advair and my dependency on my albuterol inhaler dropped from 2-3  times a day to maybe once a week.  I was off of it for years because of insurance companies dropping it, and then not having insurance.  I'm back on it now (after Primatene mist went off the market), and I'm doing great again.  It hasn't kicked in to effect fully, but I can already feel its effects.  The side effects can be bad for some people, but I'm a testament to how awesome it is."