Lubiprostone
"I've had chronic constipation for 8 years now and I can go anywhere between one to three weeks without a movement. My doctor prescribed me Amitiza and I'm now having a movement every other day. The only reason I didn't give a ten is the side effects are brutal. I've eaten a full meal and drank water and I've still gotten terrible nausea and I've even vomited from it. And the headaches don't give a good impression either. But I would rather deal with that than the horrible constipation. Overall I love it!"