Sodium hyaluronate
"I had my meniscus repaired last November after a fall the previous year. I had tried physical therapy, ice, heat, celebrex for 9 months.I have arthritis which is extremely painful. I received first cortisone shot which gave me wonderful relief for 6 weeks. Pain worsened so I needed to have knee drained on three separate occasions and more cortisone shots. My knee is still very swollen at least twice the size of my other one. I got Euflexxa shots over 3 week period. They were painful when administered. I experienced nausea and a headache after each shot approximately thirty minutes after injection.I didn't have any relief unfortunately. My surgeon feels it's time for knee replacement.  I am happy for those who report success."