Evolocumab
"I am on a long term trial with a PCSK9 Inhibitor - over 7 months now. I have had some bowel issues but after discussion with my GP and my Cardiologist, we tried 1mg of Loperamide Hydrochloride. I take this as I feel the change in the bowel, and all is well before getting to diarrhoea and excessive wind. This has worked well. Check with your doctor and cardiologist."