Copaxone
"I started taking Copaxone in mid-August 2016.  The first 3-4 months, I didn't notice any real difference. After the first few weeks, I didn't have any more site reactions.  For the last two months, I'm experiencing terrible joint pain. Leg cramps in the middle of the night, my hips are stiff; my shoulders hurt. just a little while ago, my hand was shaking sooo bad. It's scared me. So here's the thing - I'm not experiencing any of the other MS symptoms that I had before taking Copaxone. Gone are those electrical shock sensations, I'm not really  more numb, the weird feeling that runs down my spine. It seems like I've traded one set of symptoms for another.  Before copaxone, I enjoyed exercising. Now not so much. :("