Bisacodyl
"I have a history of chronic constipation and polyps. The chronic constipation comes from my daily use of opiates for severe pain/neuropathy.... I've taken generic bisacodyl many many times with "Lift Off" usually by morning if I took it at bedtime, I've never had anything other than mild discomfort with gas buildup...... but twice (lately) within a couple of months, I've taken 1 5mg bisacodyl tablet at bedtime only to awake with the same God awful symptoms many of you are describing... severe sweating, unbelievable pain as if my insides were exploding and not able to produce a bowel movement------------easily .. it concerns me if I may have another problem with polyps ( I have an appt with my gastro next week) ---"