Phentermine / topiramate
"In December 2013 I hit the 300 lbs mark after slowly gaining weight for many years.  I have tried many diets including variants of the low carbs.  In December I went to the doctors for an appetite supressent and went on Qsymia.  I enrolled in a manufactures program which gave the first two weeks of meds for free then I paid $75/ month for 3 months.  After 3 month, the price of Qsymia went up to $150/mnth (best case with coupon), so my doctor gave me a prescription of phentermine  and another of topiramate (cost 35/month total as my insurance covers the later). In 6 months I lost 60 lbs!  In the last 1.5 months I lost only 5 lbs, but my doctor explained that I should go off the meds for a few months and then the meds will be effective again."