Duloxetine
"•	19 Apr. 2016



Began initial dose at 2230 hours. Felt the medicine working within a ½ hour. Was in a good mood as I had been taken off of Warfarin this date. Before drifting off to sleep, I glanced at the clock. It was approx. 2300 hrs. I had an odd feeling in my throat that was possibly closing up. I remember worrying what is going on here? As the feeling in my throat persisted, I also felt my “Adam’s apple” fluttering and an elevated heart rate. I soon fell asleep. No other meds taken except for Atorvastatin.



•	20 Apr. 2016  



I awoke a 0600 hours to go to the bathroom. Upon arising, I felt a damp spot at the back of my underwear. Pulled the sheets back a discovered I had Shit the bed in my sleep. Felt real dizzy and drowsy. Thought to myself “how & why?” this happened. Went to shower.



As the morning continued on at 0630, the side effects were evident:

1.	“Hot flashes” Absolutely miserable. Could not get / stay comfortable. Firstly, had the flushing sweats, then I would get too cold. Turning off the air conditioner and fan for about a half an hour, Becoming hot again. This has continued on and has not stopped. Extremely bad migraines as well since waking and did not let up at all. Sensitive to noise, light and sounds.

2.	The same feeling in my throat upon waking, I drank water to cool off and see if this would stop. And it didn’t.

3.	My face was tingling all over as well.

4.	Moderately nauseous upon standing up or sitting down. The nausea had continued all day. Had a special K cereal bar to ease this up in the morning. Having only relief from it less than an hour.

5.	Tried eat cereal for lunch and discovered unable to eat it at all. The taste of it was making me sicker.

6.	Took two 500 mg acetaminophen at 0700, relief was only slight and the head aches returned less than two hours.

7.	Overall neck pain eased up and other arthritic symptoms did as well. I could definitley tell a difference, However the head ache did not.





8.	Decided to take a dosage during the morning at 1000 hrs. To avoid loss of bowel control in my sleep. Within about two hours, felt it working through my system. Same effects I mentioned as before. Severe headaches and Nausea all day. And of course unbearable hot & cold feelings again thinking that these should eventually pass as I become used to it.

9.	Laid down from 1400 to 1700 to alleviate the symptoms. Awoke from the nap and tried to eat dinner. One bite made me sick to my stomach. Headaches still there. 

10.	Overall, felt the same until bedtime as I did all day. Will give it one more try tomorrow morning.

Did not take any meds except Atorvastatin, and two acetaminophen.



•	21 April 2016



Awoke at 0815.  No bowel leakage. Took another dose of Duloxetine at 1000. Was able to tolerate a cereal bar.  Noticed the side effects once again and unable to have a bowel movement, within an hour of trying.  I will now stop this medication.  As I do not feel well at all and its side effects are terrible."