Spironolactone
"I always had perfect skin as a teen until I hit about 24 then it went down hill. Nothing worked, most topical treatments made it worse, Proactive made it worse than worse, Murade and others as well. Nothing worked. Sooo I researched spiro and found my symptoms and timing etc. fit others my age, 37 that dealt with it late in life. I asked my Dermatologist about it and she gave it to me along with a topical gel. I have only been on it about 1 week but I can see the difference already. My skin is evening out, the large pores seem smaller and the hard bumps are nearly gone. I have not had one break out and even my back is much clearer. It is amazing. I don't pee too much more but I do find I get out of breath easily. Seems to be working on my skin"