Spironolactone
"I am a 40 year old woman who's been struggling with mild-moderate and cystic acne in varying degrees since I was 11. I've also had very oily skin. I've been prescribed all the usual medicines: antibiotics, birth control pills, various topical creams and really, nothing has made any significant improvement. When I turned 40, 4 months ago I decided after doing extensive research, to ask my doctor about spironolactone. Since I'm not looking to become pregnant, she thought we could give it a try. So I've been on 50mg once a day for 4 months and this medicine has completely changed my life. My skin is not oily anymore and my cystic acne in my back is gone. My face is clear of acne. No side effects. But why didn't any dr/dermatologist prescribe this for me years ago?"