Isotretinoin
"I am an 18 year old girl who has had acne since the fourth grade. I have been on countless medications to try and help my skin; Tetracycline, Minocycline, Doxycycline, and Ortho Tri-Cyclen (birth control). None of these helped. I have used Proactive (twice) that didn't help in the least bit, so my last resort was Accutane. I was very nervous about it, having done my research on it, I wasn't sure if I wanted to. Well, let me tell you, I am so glad I did. I am only on my second month, and my skin is so smooth. Before, I had cysts and nodules all along my jaw, my neck, my chest, my upper back, and my cheeks. Now, they're flat and fading. I don't have any on my face, my chest is now drying out, and my neck looks better. "