Losartan
"Losartan gave me painful backaches and pretty severe swelling in my hands and feet.  Because of this, I had to take a potassium supplement for the backache and then hztc for the fluid retention.  I do not like having to take two medications to control the side effect of one medication.  Those issues got under control, but now it has given me chronic diarrhea so I have to switch.  All that aside, Losartan does control my blood pressure very well, and I've had issues with Norvasc, Lisinopril, Bystolic, and Clonadine.  Maybe I'm sensitive.  If you have hard to control blood pressure, this might be a powerful drug that will work for you.  I ended up in the ER once with 220/150 (on Norvasc) and Losartan HCTZ got me in control really quickly."