Buprenorphine
"When the doctor gave me these patches I had a a "yeah right" attitude.  I am  stunned! I applied the first patch and 3 days later I had significant pain relief! I just applied my 2nd patch and I am able to resume doing a lot of things I haven't done in years. I had side effects at first, sleepiness, shakiness, and severe nausea but they passed within the first week. I am amazed and pleased at the effectiveness of these patches."