Orlistat
"I lost 10lbs in one month from taking Alli. And 17 all together after 3 months. It works without a doubt! Unfortunately for me, it also had a bad side effect- considering that my lifestyle and circumstances haven't changed I can narrow it down to Alli: I became extremely depressed. It blocks out all fat including good fat that your body needs. So, after speaking to my doctor, I sacrificed my weight loss for my mental health, I stopped taking the drug and now I am back to my regular old self after 6 weeks. Depression is a TERRIBLE.  I will never take alli again or any fat blocking drug. Right now I'm doing it the hard way: portion control and plenty of water. I will also add that was my first time ever that I suffered depression"