Mirtazapine
"I have been taking low dose mirtazapine (3.75 mgs) for about 10 wks now for anxiety, insomnia and mild depression. I was prescribed this after being unable to tolerate SSRI anti depressants and having a very bad reaction to Lexapro. Mirtazapine has worked well for insomnia and I started noticing improvements in anxiety levels and mood within 3-4 wks of starting.  I initially had a mild increase in appetite but no weight gain, and my appetite is now normal. The drawback to this med is daytime fatigue/groggy sensation that does not lift until late afternoon. I was told this would improve with time, but it has not. For this reason I will likely taper off the med soon - not something I can put up with long term despite being effective for insomnia/anxiety."