Bupropion / naltrexone
"I just hit my 6 month mark so I wanted to update my review.  While I experienced several side effects at first, some severe, they all went away eventually.  I am losing 2lbs a week up to 10lbs a month.  I'm noticing there's a pattern for me of losing ~10lbs very quickly, then stagnation for a few days, then loss starts again.  I'm improving my diet, but it is by no means perfect, and I'm able to have more energy to get off my butt and exercise or do tasks I would otherwise procrastinate to high heaven.  As someone who has failed (a lot) in the past, this is a miracle drug for me because for the first time ever, I am able to know my hunger and eat without counting calories, carbs, fat, whatever and confidently lose weight.  Yay!"