Opcon-A
"Opcon-A relieves my eye soreness and eliminates redness better than any other over-the-counter product (such as Visine) and Pataday (Rx and a bank loan are required, but it causes eye twitching after a few days of use as Pataday instructs).  I use Opcon-A once or twice per day only on days that my eyes become tired due to combination of chronic dry eye, possible eye allergy, and lack of sleep. (My eyes are red even on good days except for a while after using Opcon-A.) At age 58 now, no side effects have been observed despite occasional use for many years."