Topiramate
"I used Topiramate for 12 months for migraines which helped enormously, reduced them to 1 or 2 a month from the 10  .  Great side effect was the weight loss on 50mg, lost 60 lb but the migraines started getting worse so increased the dose to 100mg and had a LOT of side effects, periods stopped, body aches, palpitations, slow heartbeat, fatigue, memory loss the list was endless. I came off them altogether and migraines just came back as before and I put on 16lb weight in a month!  All the other side effects disappeared.  I have stayed off them for a month and am about to reintroduce them as I cannot stand the almost daily migraines. (And I don't want to put any more weight back on) this medicine works well but you need to get the right dosage."