Modafinil
"I have been working for many years with one combination after another of medications for bi polar disorder. I was recently on oxcarbazapine and lithium which was great for a few months. Depression came back and I had unpleasant side effects with the oxcarbazapine. My doc added modafanil. It reduced the side effects and improved my depression. It also caused irritability. And caffeine made me restless even with a small amount."