Quetiapine
"I started taking low dose Quetiapine (Seroquel) 3 years ago for sleep and anxiety, instead of Lorazepam (Ativan), which was losing its effectiveness. I also take Escitalopram 10mg daily for depression. The Seroquel has been fantastic - I only take 1/4-1/2 of a 25mg tablet as even 25mg was too sedating and even after 3 years of almost daily use, I have not needed to increase the dose. I also occasionally go a few days without taking it and do not have any withdrawal symptoms. I normally take it only at night to help sleep, but occasionally during the day for anxiety. I have not had ANY weight gain, increased appetite nor other side effects, but perhaps I am just lucky to be sensitive to such a low dose, avoiding these common side effects."