Sumatriptan
"When I moved to Indiana I started getting migraines . My doctor prescribed imitrex 25 mg which worked beautifully as long as I took it when the migraine started. Though it still doesn't always work and I take another dose 2 hours after the 1st dose. I developed tolerance to it and now need to take 50 mg. Fortunately my migraines have slowed down to a dull roar as I've figured out my triggers. Imitrex has some annoying but mostly tolerable side effects that dissipate with use, such as feeling physically fatigued, feeling kind of drugged, trouble thinking clearly, increased blood pressure/heart rate, sometimes I feel shaky."