Brimonidine
"Am a 36 yr old male, Celtic bloodlines both sides and until 9 years ago of suitably pale disposition! Have rosacea for 9 yrs and have been on antibiotics (minocin 50mg) for 8 of them, along with annual IPL therapy. Was off the minocin until last week for a year when my dermatologist put me on 100mg and also prescribed me Mirvaso. I seem to have a reaction to the 100mg with red blotches and spots, so after 3 days I tried the Mirvaso. Used 3 times over 4 days. Worked a dream the first day, but effectiveness wore off. Last 2 days have suffered very very bad rebound flushing, tingling on cheeks followed by burning sensation. Hottest parts of flushing nearly purple. Booked in for IPL today to try and reduce redness/purpleness. Avoid."