Rituximab
"I have had wegeners since April 2008.  Medications of prednisone, cyclophosomide, and methotrexate were successful in slowing down the disease. However I still had flareups a two three times yr requiring hospitalization and the resumption of heavy doses prednisone till better, then had to taper back off.   In June 2013 I again was back in hospital and in Sept 2013 I started on Rituxan getting 2 doses 2wks apart & again six months later.  I only take 5 mg of prednisone a day and remain on methotrxate 20mg once per week.  I have eliminated hospital visits & have enjoyed life much more. I am just finishing this month my 2 dose shots & now looking in 6 months reducing it to one dose every six months and reducing my methotreate to 15 mg .Side effects minor"