Amitriptyline
"I was put on this medication for interstitial cystitis and before I had suffered severe bladder and abdominal pain for almost 2 yrs before I discovered I had IC. I would have the most terrible bladder pain and not be able to walk or get out of bed or I would have severe bladder spasms and would wake up in the middle of the night and go sit in a hot bath to relieve the pain. The hot baths were the only thing that made the spasms not so so bad. One weekend I had a terrible flare up and the baths didn't work nothing did my doctor put me on 10 mg of amitriptyline and it has really been a huge life saver. I can't say I don't have flare ups now and then but the pain is now where near what it was."