Selegiline
"I've been taking selegiline (Emsam) for depression for three years after 40  of pretty much everything else. This has been the most effective treatment I've had, lasting the longest with the best results. Side effects have been limited to skin irritation from the patch. The dietary restrictions aren't proving to be too restrictive. On a couple of occasions, I've had food with tyramine by accident. A bad headache for a few hours was the only result. (I didn't realize that I'd had the tyramine until after the headache had come and gone.)
The price and need for prior authorization are my only real complaints."