Adapalene / benzoyl peroxide
"My dermatologist gave me some samples of Epiduo and I tried it. Now, of course I know the saying, "it gets worse before it gets better." However, in my case it got much much worse, alot worse than I ever had. Bad enough where it greatly effected my self esteem. About two weeks into it, I had to stop because my face was burning really bad and it looked worse than ever. So, I stopped taking it because it was the type of acne that would leave scars so I stopped and used the other sample he gave me, which is Tazorac gel 0.1. Since I've been using that, it has cleared up my skin very well. Still have improvements to go but I like what results I'm seeing now. So,   Epiduo didn't work for me but I guess it does for some people."