Estradiol
"I was first placed in the generic estridol patch made be Mylan and suffered with theses horrible patches for 3 months until my Dr agreed to place me on the brand name. First of all I had very little relief from my symptoms due to the genetic bullseye (it's approx 2 inches round) falling off! The adhesion is subpar therefore I was not receiving adequate efficacy from this product. I used tegaderm and even waterproof medical tape to keep the patches on but doing so caused skin tears and irritation. I just started the new Brand this week and I am hoping for better results. It is much smaller and hasn't washed off on Day 2 yet."