Infliximab
"I have been on Remicade for nearly 4 years.  Prior to that I had a variety of Crohn's issues including two surgeries for peri-anal fistulas, severe fatigue and lots of other fun stuff.  I have been very lucky in that I have responded very well to the stuff and now most days I am fortunate enough to forget I have the disease.  I was apprehensive about potential side effects but to date have experienced none.  Prior to Remicade I took a few medications which did absolutely nothing but the Remicade had a pronounced effect within 24 hours of my first infusion.  If you have Crohn's or Colitis would seriously consider an anti TNF blocker (haven't used any of the others) and stay the hell away from steroids."