Morphine / naltrexone
"After sucessfully taking Avinza 120 3x daily I was selected to try Embeda 120. I took my 1st dose shortly after leaving the Pharmacy. Stopped for a take-out sandwich. When I reached home I started feeling strange...by the time I walked into my kitchen I heard a loud sound like cicadas in the trees...thought " this is springtime, what are they doing out?" Then I realized the sound was in my head. Got super dizzy, barely made it to the bed before experiencing instant, total withdrawal symptoms. And no, I didn't crush the Embeda  just swallowed it. I writhed around the bed for 8 hours in violent convulsions, badly hurting my knees which needed replacement. Found out later I was one of the 8-12 % who carry an enzyme that releases the Naltrexone"