Lithium
"I have tried other medicines for Bipolar Disorder and some worked and some did nothing. Lithium made me feel strangely dull and sleepy the first two weeks but I wanted to give it a good chance. Around the 15th day, I woke up and felt fine, two months later I still feel fine. I am also taking 15mg of Buspirone and 20mg of Celexa. I never thought I would be able to really live until now. My moods are not extreme anymore and I don't have suicidal thoughts. It is like a switch was slipped. 
My doctor started me at a very low dosage of Lithium, I am so glad she did - I only need 300mg once a day."