Methotrexate
"Second time around with the methotrexate .I use it as a bridge drug until I find one that works. I was on enbrel and humira for past 15 yrs. both worked extremely well but lost potency after about 7 yrs. Now in search of new drug now trying Otezla it's not a biological and has less side effects of all others I have researched. I don't like the methotrexate. Long  term because of hair loss and the continued dosing changes. But fortunately now we have many drugs to choose from finding one that works and is safe and effective is the dilemma."