Bupropion / naltrexone
"I am on day 15 of taking Contrave. I took one pill/day for the first 10 days & have been on 2/day for these last 5. Days 1-6: gnawing headache at least once/day; insatiable thirst; significant constipation. During that time, I had decreased appetite, but I think that may have been due to the constipation-there is just nowhere for the food to go! After "clearing" things out with miralax I have a more normal, healthy appetite. No urge to binge and know when to stop. When I started 2 pills per day, I was again very thirsty, which is better in the last day or so. No headache with the increased dose. Down 2.4lbs, but I haven't exercised at all, so "only" 2.4lbs in 15days is perfectly fine with me. I look forward to seeing the long-term results."