Adapalene / benzoyl peroxide
"I bought this gel a few years ago and stopped using it as it wasn't that effective on my skin. However recently I started applying this along with a few other products and it was great. For me, I find it most effective when I apply it twice a day on the painful cystic pimple (normally on my nose). I wash the acne prone areas on my face with a wash that has salicylic acid 2%, then use a toner with witch hazel or a cotton pad soaked with pure green tea. I apply retinoid, let it sink in and then I apply Epiduo on those areas. I think it's important to use it as spot treatment if you're overly sensitive like me. If you're feeling dry I apply a cream with hydrocortisone over it at the end. My pimple bump disappeared in two days."