Isotretinoin
"My son had severe acne. We tried every prescription and non-prescription topical cream and also the oral medications, minocycline and doxycycline. Nothing worked and he was struggling for 2 years with self esteem crushing acne all over his face. I was hesitant to have him try Accutane because of all the side effects but I'm so glad we decided to have him try it. He started at 40 mg the first month and then switched to 80 mg for 5 months. His face is completely clear. I call this a miracle drug.   It's not for everyone and please realize there are some serious side effects for some people. My son mainly just had chapped lips and some peeling skin but nothing that wasn't manageable with moisturizer and chap stick"