Spironolactone
"I was on Diane 35 for seven yrs (15-23 my skin was amazing) What I didn't realize was that Diane Caused me to gain a lot of weight, I put it on almost immediately (age 15) and struggled with weight issues and an eating disorder. When I stopped Diane at 23 to have kids, I quickly lost about 15 lbs (5lbs of water) and my insane appetite as well.  After children I wanted to go back on Diane for nice skin. I promptly gained the weight, eating issues returned! So I quit and decided to try spiro. 25 mg once a day. My skin started clearing immediately but Within 3 weeks I had weight gain, aged 5 yrs, along with other horrible side effects! Since quitting for two days I feel myself again! I'll stick with Skin Ceuticals Acne Kit and zinc supplements!!"