Spironolactone
"I am a 22 year old female who had painful, cystic, lumps that would form deep in the skin around my mouth and would get worse with my hormone cycle. I went on YAZ as it is the only birth control proven to help hormonal acne and the progesterone in it, drosperinone, acts very similar to spiro. This helped but then school got very stressful and the acne got worse. I went on 50 mg of spiro and it definitely helped cut down on the number and severity of acne. After being on the 50 mg for 4 months, I moved up to 100 mg and have had 0 acne since!!! Not exaggerating. YAZ completely cleared my 21 year old friend's hormonal acne up but mine did not clear until adding 100 mg of spiro, so try things out to see what will help!"