Depo-Provera
"I was on Depo for twoish years. The first year was great spotted 3 months in and then never had a period at all. And then beginning mid second year everything changed. My mood swings were though the roof I gained 10-15 lbs I felt depressed. It definitely does the job of preventing pregnancy but the side effects were through the roof. I live an active lifestyle work out 2-5x a week and have been doing weight watchers for 1 year my weight is always up and down but I feel like its a cycle. I get motivated for a few weeks lose a few pounds and then get depressed and stop caring. I talked to my doctor and she does believe it is from depo. So I went back on the pill."