Spironolactone
"35 years old.  I've been on spironolactone for about 7 weeks now.  I began noticing changes right around week 4.  My skin is almost as clear as it was years ago when I was on Accutane.  Pretty much no side effects as of yet (knock on wood).  I've been on every medication possible and nothing worked.  Finally I went to a new dermatologist who prescribed spironolactone and I wish I would've found this sooner.  I rarely get a pimple now and the only one that I have gotten has been really tiny and has gone away after a day.   I hope the success continues."