Bupropion
"I just was put back onto Wellbutrin after attempting 3 other antidepressants.  It was only after being off it that I realized how good it worked for me. I was taken off of it because it caused me to have some issues with irritability and according to my family- short tempered.  I was put on Cymbalta, but I enjoy a drink or 2 a day with my wife (Cymbalta and alcohol will destroy your liver- very well documented).  Zoloft made me feel completely despondent, and I felt life was no longer worth living, not to mention made me not even remotely think of sex.  When I was put back on Wellbutrin, I felt like life WAS worth living, and I feel happier and euphoric.  Now I take Lamictal with Wellbutrin 150 mg in the morning.  Avoid the XR- causes insomnia."