Ondansetron
"I had surgery and the post operative narcotics made me very nauseous and I had to throw up. A full dose (8 mg) of ondansetron helped but did not fully resolve the problem. Then I got Phenergan and all the nausea was finally gone. I think, for me, Phenergan is a better anti-nausea medication, but while ondansetron (Zofran) barely made me sleepy, Phenergan made me very sleepy. (I actually think, if you are at home or in a hospital, it is much better to take Phenergan as it seems to help more and also gives you a good sleep. If you need to go to work or school, you should take Zofran. "