Interferon beta-1a
"I was diagnosed with Multiple Sclerosis 6 years ago. I had/have mild symptoms. I began taking Avonex immediately and have had no significant change in symptoms. I take 1 Aleve an hour before my injection. I chose the last night of my work week so I can't dread "the day."  I rotate my injection-left thigh, left hip, right hip, right thigh. I think this will help avoid irritation, though I've never had a problem anyway. My husband gives me my shot so I don't have to look at the needle. I also cough because someone told me you can't tense other muscles during a cough. I relax, and he injects the needle on my second cough. Many times I don't feel a thing. When I do it's minimal. Hip shots are the easiest. I always make sure the Avonex is at room temperature."