Amitiza
"I was nervous taking this after reading the reviews, but this medicine has been great!  I first started out taking the 8mg twice a day, and was using the bathroom every third day.  I moved up to the 24mg twice a day, and I actually use the bathroom once a day.  The first time I took it, I did have stomach cramping during the night, but that just lasted for one night. I have had no side effects what so ever.  My stool is actually what it is supposed to look like and I feel great.  I used to be on Zelnorm and I miss that so much, but this medicine seems to do its trick.  Hopefully this one will stay on the market.  Don't be afraid of trying this at all after reading some other reviews."