Bupropion / naltrexone
"I'm through my first week.  First two days had a lingering headache most of the day and a few hours of nausea.  No weight loss but I didn't expect it yet.  Start with the second pill tomorrow. So far..... my appetite overall has decreased as the week has gone on.  I've noticed that I may still want a snack but I can walk away from it and not eat it. I'll post again at the end of my second week."