Estradiol
"I've been using Estring for 10 years without any side effects whatsoever.  Just recently have gained 10 lbs and can't figure out why.  Also cannot get it off.  Perhaps it's time to stop the treatment and see what happens.  My question if anyone can share, once stopped, does the sweating and other symptoms return?  I've just turned 60 and feel great.  Don't want to have the unwanted effects.  But totally open to stopping the Estring if it's dangerous to continue after all these years.  My most recent dr said it's ok to stay on it even though mother and sister have had breast cancer."