Exenatide
"This is an update from my previous posting. I need to correct that I take 1000mg of Metformin NOT 2000mg a day. On Thurday I took my 4th injection of Bydureon. At first I had some nausea and heartburn. By my 3rd injection that has subsided.  As far as weight loss, I've only lost 9lbs so far. My fasting sugar in the morning the day after injection is about 118. However, as the week goes on they tend to spike. The highest I've had is 185. Before Bydureon I ranged between 120-150. I've also noticed that my ankles swell by the evening time. Which is somewhat new. During these four weeks I had stopped my Actos because I couldn't afford the copay and but I was able to restart it this week. I put a call into my doctor. I'll see what she has to say"