OxyIR
"Recently my doctor changed my breakthrough pain medication to Oxycodone 20mg from OxyContin 20mg. Immediately I noticed a huge difference, and for the first time in four years felt that my pain controlled. Now I'm taking OxyContin 80mg twice daily with Oxycodone 20mg every four hours prn.  Overall oxycodone provides the quickest and most effective pain control above all oral narcotics I've taken. However I do caution long-term users of increases in tolerance, monitoring if ever more medication is needed to achieve the same effect. I first noticed an increase in my tolerance two weeks of taking 4-6 tabs daily. I gradually increased my dose until I was needing double my starting dose. Within one month my tolerance increased by two-fold."