Imiquimod
"I've just started this near my anus area and can't believe how sore and unpleasant it really is,  my bum is on fire! Not sure if working but please take note if you have been prescribed this stuff - use very very tiny amount. (until you get use to it). Twice I have tried it and I can't walk,  sit,  bath,  worried to do anything because of the pain unreal. 



Don't know if it's working as only on week one so will keep you updated if it works."