Estradiol Patch
"I used the patch for night time hot flashes that wake me up every 2-3hrs. The size was great, and it stuck just fine. That's where the happy union ended. By the second day the hot flashes seemed to triple, occurring all day and all night. And the flashes were hotter! I also began to have terrible headaches that woke me up earlier than my alarm clock and hung around all day. I never have headaches so I removed the patch after only 4 days and the symptoms all went away. Now I'm back to square one better able to deal with my original symptoms knowing things could be worse. I'm going to give the name brand Vivelle dot a try and see what happens."