Wellbutrin
"Age 48 and have struggled with depression for years. I have no other MH disorder and had no luck with antidepressants. Prozac increased suicidal ideation and with Zoloft I felt occasional "zapping" in my brain (I have no other way to describe it, but it's happened to others). Finally decided to try Wellbutrin 150 mg QD. I'm mad at myself for not trying it sooner! Now, depressive episodes are very infrequent and last less than 30 minutes. The low is very manageable, however at times when I should be sad, it's like I can't be. I also have tons of energy, when in the past I'd struggle to get out of bed. Unfortunately I haven't had any weight loss. The down side is that I am experiencing some insomnia, but I'd rather that than the alternative."