Nortriptyline
"Been having worsening migraines for 8 or more years. Tried so many different things, I am basically disabled at this point sick almost daily from either migraine or rebound day. After Topamax, steroids, beta blockers, you name it I've tried it. Finally I've been put on nortriptyline, after 2 weeks I haven't had a single migraine. I hate to be skeptical but it's almost too good to believe for me since I've been sick so long, so I will be reporting back soon. But I even feel differently just how my brain feels. Right now I'm quite thrilled and the results seem to be what's reported by everyone else here (taking 25mg at night)."