Lifitegrast
"The liquid generally sticks at the end of the vial, so you have to "flick" at it to push it towards the tip before twisting off the cap.  Xiidra leaves a bitter taste in my mouth for a good 30 mins. It causes watery eyes for about the same time too.  2 times every 12 hours can be a pain. Some days I forget and end up doing it once every 24 hours. It's been 4 months now and it's help a little bit. Won't know for sure if my dry eyes are "cured" after 12 months of use. We'll see when I get off it."