Qsymia
"Started June 2015. Began highest dose January 2017. I've lost 60 pounds altogether so far. Still have 60 to go. Slow and steady wins the race. You have to put effort into this with diet mostly. I didn't exercise much the first year until I got some weight off, now I do exercise almost everyday because it feels good to do so. Those reviews you see of people not having appetite suppression in the first few days, well, that's not how the pill works, you are on a trial dose for two weeks, to see how your body adjusts to the medication. 

  I have great appetite suppression at the beginning of starting a new dose, then it wears off after a couple months, you can increase doses when you stop loosing weight.  It's approved for lifelong maintenance."