Bupropion
"This medicine has been the best at treating my depression. I've tried Prozac, Pristiq, Effexor and Trintellix and Wellbutrin's stimulating properties are what have made this drug so effective for me. Every other antidepressant I've been on has made me feel drugged, zoned out and tired. Probably the best out of all the other antidepressants I tried was Effexor, but even then it triggered what I know believe to have been manic episodes. 



Sad thing is that this drug is no longer effective for me after 3 years."