Doxylamine / pyridoxine
"I have been feeling pretty nauseous all day (first trimester of pregnancy) and my healthcare provider gave me a sample of this drug to try.  I wanted to share my experience as all I've read are glowing reviews... Glad it's working for some people but have to imagine there are others who experienced something similar to me.  I have taken it now for 3-4 days which should have been enough time to get a feel for whether or not it works.  It did absolutely nothing for my nausea.  If anything, it made me feel worse.  I was so tired I couldn't function.  Had to lay down in the middle of the day for a few hours, was feeling so tired and sick. I didn't take any last night and today I feel better than I have since I started taking it!"