Amitiza
"I have been on laxatives forever. Specifically, Perdiem. I take 3 Perdiem and 1 Amitiza at bedtime and go every morning. The Perdiem (similar to Senokot) was starting to not work as well after 25  years and once I added the Amitiza, all is well. I am trying to cut back on the laxative now. My doc wants me to take Linzess, but I'm reading how many people are gaining weight. My only complaint with Amitza is the gas, so I am reluctant to take in the morning."