Linaclotide
"I'm taking a sample my GI doctor gave me. He gave me one sample. I started with the 145 mcg.

It works very quickly. Don't take it if you have any plans for the next several hours. 

This may be just me, but once things get started, they don't like to stop until every drop of moisture has been wrung from my guts. I'm planning on asking for a prescription for Bentyl or Motofen to get my guts to calm down when it's clear it's no longer necessary.

"