Asenapine
"I have been taking Saphris 10 mg once in the evening for 6 weeks now. The taste is terrible but I was feeling wonderful for the first time in years.  Now, unfortunately my tongue is sore, I've lost all taste sense and my teeth ache especially when I bite down on things.  I'm diabetic and my sugar is a bit elevated but I've been able to adjust insulin for that.  I sleep like a baby all through the night now but my feet, ankles and calves are so swollen, I can barely walk.  I can't believe that I've developed this edema and I think I'm going to have to go off the medicines.  Too painful."