Bupropion / naltrexone
"I discontinued using this after 2 weeks due to the side effects I felt: nausea, sweating, dry mouth, trouble sleeping.  I think I may have lost 1-2 lbs during that time. I guess it works because you're too sick to eat anything and lose weight that way.  It didn't work for me.  It's also very expensive and most health insurance does not cover it.  One month supply that I ended wasting most of the pills was $92."