Furosemide
"I've been taking Lasix for about 10 years for swelling in my feet/ankles. I only have one kidney and have hypertrophic cardiomyopathy.  I take 80 mg in the morning.  It does not always take all the swelling out, but if I miss just one dose, I can tell it by the afternoon.  Of course, if I take it in the afternoon, I'm up all night.  NOTE: There IS a difference in taking the Lasix as opposed to the generic furosemide.  For me, the generic is absolutely useless.  My mother had the same problem, so maybe it's genetic.  I've taken as much as 200 mg of generic at one time with no effect whatsoever.  I've noticed no side effects from the Lasix."