Miconazole
"I was very nervous after reading the reviews for the monistat 1 and 3 so I decided to go with the 3 day pre filled applicators. I've only done the first night so far but that seemed to be the worst part for everyone else. I got a YI from taking antibiotics. I put the medicine in right before I went to sleep in bed and didn't have any issues what so ever. I think people are having issues because they've been itching and making the skin raw down there so of course when the medicine does eventually start leaking out it burns. Just like a scrap or cut would when something first touches your raw skin. Also for me after I put the medicine in I was already laying down and didn't have to get up, I just went to sleep. No burning/itching present!"