Desvenlafaxine
"I'm day 4 on Pristiq.  I've always hated being medicated to treat my depression and anxiety, for some time I had been doing okay with managing it on my own but recent events in my life sent me for a downward spin so I had to start the medicine. The first day was awful, I was dizzy, nauseated, shaky and for a period of 2 hours I was hit with a serious wave of paranoia I've never felt before. I wasn't keen to keep taking it after that but I've stuck it out. My doctor had to give me a sedative to help level me out because I was going up and down, mood completely unpredictable.  Today is the first day I've taken the sedative with Pristiq, so far so good. I've had to be on leave from work until things are a bit more balanced."