Adapalene / benzoyl peroxide
"So I was prescribed this medication a while ago, but I basically gave up every time things got painful. That for me, was about 5th day in. I'd been told to persevere and that the pain and dryness would stop after the first 2 weeks. But I decided to only use it when I had breakouts. However, this medication brings out the acne before clearing it, so of course your acne is going to get worse before it gets better. 



HOWEVER, I now use it everyday. I have very sensitive skin so I can't use a lot of moisturisers because they burn. But I'm using some Garnier moisturiser and an oil based one from lush whenever my skin feels a little dry, and I have not had a painful night since. And no extreme dryness or flaking either. Brilliant!"