Duloxetine
"I've suffered from anxiety and depression off and on for most of my life. I've tried many antidepressants (mostly SSRI's) without success. The side effects of these drugs were unbearable (mainly acute insomnia and panic attacks). Finally, after 30 years of intermittent mental suffering, despite running 30 miles a week and seeing a therapist on a regular basis, my primary care physician prescribed Cymbalta. It is a miracle drug. Although I've only been on it for 3 weeks, I'm already feeling relief from a major depression that started 6 months ago. I no longer have suicidal thoughts; negative, obsessive thinking; panic attacks; and I sleep like a rock. the world is so much brighter - I feel a sense of calm, contentment, and happiness."