Linzess
"I was born with heirschprungs disease and have fought constipation all my life and as I've gotten older, it's getting so much worse. I took Zelnorm when it was on the market and it was a dream come true. Unfortunately it was pulled for possible side effects. Duh ... what meds don't?  I've used Linzess 3 times now. Yes, it cleans me out but I have horrible stomach cramps and severe diarrhea. But as others have said, it's far better than being constipated for days on end.  I so wish someone would/could bring Zelnorm back.  Best solution there was. Will only use Linzess on occasion."