Method for manufacturing a tonic composition for man and other animals
BACKGROUND OF THE INVENTION 
     This application is a continuation-in-part of Ser. No. 481,235 filed on June 20, 1974 for &#34;A TONIC COMPOSITION FOR MAN AND OTHER ANIMALS AND A METHOD FOR THE MANUFACTURE THEREOF&#34;, now abandoned. 
    
    
     It has heretofore been known to use wood vinegar as a smoking agent for fish meat and to employ it as a soil sterilizer and fungicide, as a repellent against nematodes inhabiting soil, as a deodorant for pigsties and henhouses, and as a preparation for cleaning and deodorizing rivers. Wood vinegar is a liquid composed of around 200 different organic compounds including about 3% acetic acid, about 1% other organic acids, a little less than 1% methanol and traces of aldehydes, ketones and phenols. Since these are invariably produced by the thermal decomposition of wood, wood vinegar is recognized not to possess any violent toxicity. Among the organic compounds present therein, however, formaldehyde, methanol, benzpyrene and benzanthracene are recognized to be harmful when injested by living creatures. Particularly, benzpyrene and benzanthracene are regarded as carcinogenic substances. It is, therefore, recognized to be harmful and improper for wood vinegar to be admixed in its unmodified form with food and consumed by man and other animals. 
     The present inventors studied wood vinegar in looking for a tonic composition which is free from these drawbacks and yet usable for man as well as for other animals. They discovered that refined wood vinegar is obtained by allowing wood vinegar obtained by a conventional method, or preferably wood vinegar of the type produced from nine or more different types of trees as raw materials, to age by standing at rest for several years then refining the aged wood vinegar by thoroughly removing soluble tars unsuitable for ingestion by living creatures. Further, by adding leaves of a plant to the refined wood vinegar and allowing the leaves to be permeated by the wood vinegar they have obtained a product which, when added to feed and taken by domestic animals, encourages the animals to take the feed, promotes their health and growth, deodorizes their excrements as well as their bodies, improves the hygiene of their environments and consequently prevents otherwise possible public nuisance. Also, when taken by man, the product serves to promote his health. This knowledge has served as a basis for the present invention. 
     SUMMARY OF THE INVENTION 
     The present invention provides a tonic composition in liquid form for man and other animals made up essentially of refined wood vinegar containing plant leaf components. 
     The present invention further provides a tonic composition for man and other animals in a form of powder or granular solid in which said liquid tonic is absorbed on a soft amorphous carbon powder. 
     The present invention also provides a method for the manufacture of a tonic composition for man and other animals, comprising adding leaves of one or more plants to refined wood vinegar to ferment or permeate the leaves in refined wood vinegar, thereafter filtering the leaves&#39; residue and refining the filtrate. The refined filtrate may be adsorbed on a soft amorphous carbon powder, to provide a tonic composition in solid form. 
    
    
     BRIEF DESCRIPTION OF THE DRAWING 
     FIG. 1 illustrates a manufacturing process of the present invention. 
     FIGS. 2 to 6 illustrate the efficacy of the tonic composition prepared by the present method. 
    
    
     DETAILED DESCRIPTION OF THE INVENTION 
     The refined wood vinegar to be used for this invention is produced as illustrated in FIG. 1 by refining wood vinegar obtained by a conventional method or by chipping trees (enumerated herein below) or barks of such trees, placing the chips in a metallic retort or a kiln built with stones or bricks, roasting the chips therein in the absence of air to obtain volatile substances produced by the decomposition of water and wood compounds contained in the chips, liquefying the volatile substances through a condenser, allowing the liquefaction product to stand at rest, withdrawing the wood vinegar occurring as a supernatant, allowing this wood vinegar to stand at rest in a storage tank for several years, more preferably over five years, and subjecting to washing and distillation with benzene the supernatant or the upper of the two phases into which the wood vinegar is separated after the standing. The soluble tars which have survived the first washing and distillation with benzene are repeatedly subjected to a procedure of separation comprising the steps of distillation, agitation and standing until complete removal is obtained. Consequently, there is obtained refined wood vinegar which is completely free from benzpyrene, benzanthracene and other substances unsuitable for ingestion by living creatures. When the crude wood vinegar is left to stand at rest for several years, or preferably for more than 5 years, it matures and soluble tars partially dissolved therein sediment to a lower phase, so that highly refined wood vinegar is produced efficiently. Since the tonic composition according to this invention is intended for use by man and domestic animals, the removal of substances unsuitable for ingestion by living creatures must be effected to a thorough extent. 
     The leaves referred to in the present invention are preferably comfrey (Symphytum officinale) leaves or a mixture of leaves the majority of which are comfrey leaves and including leaves of bamboo (bambusa), garden radish (Raphnus satious) and matrimony vine (Lycium vulgare). Sasa albomarginata can be further added therein. They may be added to the refined wood vinegar from which substances unsuitable for ingestion by living creatures have been thoroughly removed as mentioned above and allowed to stand at rest for three to five months. Alternatively, the comfrey leaves of the mixed leaves are completely replaced at intervals of one to three months, preferably of two months, over a period longer than one year. Consequently, the leaves are sufficiently permeated in the refined wood vinegar. Thereafter, the resultant mixture is filtered and the filtrate is distilled to give rise to a liquid tonic for man and other animals. 
     Refined wood vinegar is used for the reason that wood vinegar, by incorporating various organic compounds, metallic elements and other substances, manifests tonic effects in man and other animals. The reason for the addition of comfrey leaves or a mixture containing a majority of comfrey leaves and supplementally incorporating leaves of bamboo, garden radish and matrimony vine to this refined wood vinegar is that special emphasis is placed on germanium, allantoin, vitamin B 12  and vitamin B which occur particularly in comfrey leaves. The leaves of bamboo, garden radish and matrimony vine are supplementally incorporated for the reason that components other than those present in the comfrey leaves such as, for example, vitamin K, vitamin B and vitamin C contained in the bamboo leaves, potassium, calcium, vitamin C and various vitamins in the garden radish leaves and betaine and rutin in the matrimony vine leaves function synergistically with the refined wood vinegar to give tonic effects for man and other animals. 
     For the production of wood vinegar according to this invention, although trees which are generally used for the production of wood vinegar are usable, it is desirable to use deciduous trees or a mixture of deciduous and coniferous trees. It is especially advantageous to use the nine essential species of trees consisting of (1) Akagashi (Quercus acuta Thunbs.), (2) Shirogashi (Quercus myrsinaefolia Blume), (3) Arakashi (Quercus glauca Thunb.), (4), Ichiigashi (Quercus gilva Blume of genus Quercus L.); (5) Kojii (Shiia cuspidata Makino) and (6) Itajii (Shiia Sieboldini Makino) of genus Castanopsis Spach., (7) Shiratabu (Litsea glauca Sieb.), (8) Benitabu (Machilus Thunbergii Sieb.) and (9) Camphore tree (Cinnamomum Camphora Sieb.) of Family Lauracae, and thereto to add at least one of the optional species of trees including wild cherry tree (Prunus donarium Sieb. var. spontanea Makino) and other species of the Rose Family (Rosaceae); species such as Yusu (Distylum racemosum Sieb. et Zucc.) of the Witch-hazel Family (Hamamelidaceae); Japanese oak (alias petit oak) (Quercus serrata Tumb.) and other species of the genus Quercus L., Beech Family (Fagaceae); such species as Kunugi (Quercus acutissima Carruth) and Beech (Fagus crenate Blume) of the genera Quercus L and Fabus L., Beech Family (Fagaceae); such species as Carpinums laxiflora Blume of the genus Carpinus L., Birch Family (Betulaceae); such species as Mizume (Betula grossa sieb. et Zucc.) of the genus Bebula L., Birch Family (Betulaceae); maple tree (Acer palmatum Thunb.) and other species of the Acer L. Maple Family (Aceraceae); zelkova tree (zelkova serrata Makino) and other species of the genus Zelkova Spach., Elm Family (Ulmaceae); myrica (Myrica Rubra Sieb. et Zucc) and other species of the Myrica Family (Myricaceae); scaber (Euphorbia Pekinensis Rupr. var. Japonesis Makino) and other species of the Spurge Family (Euphorbiaeceae); such species as Harigiri (Kalophanax septemlobus Koidz.) of the Ginseg Family (Araliaceae); swmp nut (Pterocarya rhoifolia Sieb. et Zucc.) walnut (Juglans mandshurica Maxim. var. Sieboldiana Makino) and other species of the Walnut Family (Juglandaceae); Camellia (Camellia japonica L.) and other species including Himeshara (Stewartia mondadelpha Sieb. et Zucc.) of the Tea Family (Theaceae); oak (Quercus dentata Thunb.) and other species of the genus Quercus L., Beech Family (Fagaceae); wax tree (Rhus succedanea L.) and other species of the Sumac Family (Anacardiacea); Japanese cedar (Cryptomeria japonica D. Don) and other species of the genus Cryptomeria D. Don, Pine Family (Pinaceae); ground-cypress (Chamaecyparis pbtusa Endl.) and other species of the genus Chamaecyparis Spach., Pine Family (Pinaceae); pine tree (Pinus Thunbergii Part.) and other species of the genus Pinus L., Pine Family (Pinaceae); hemlock spruce (Tsuga Sieboldii Carr.) and other species of the genus Tsuga Carr, Pine Family (Pinanceae); and white fir (Abies firma Sieb. et Zucc) of the genus Abies Mill., Pike Family (Pinaceae). (See, for example, pages 85, 88, 90-92, 192-194, 249, 393 and 431 of Makino&#39;s New Illustrated Flora of Japan, as a reference for identifying such species and their technical names.) 
     The desirability of the combined use of the trees described above has been demonstrated by the inventors&#39; experiment which has led to the following conclusion: When the refined wood vinegar obtained by using the aforementioned nine species of trees in conjunction with other species is employed, a synergistic effect is produced when comfrey leaves or a mixture containing a majority of comfrey leaves and supplementally incorporating leaves of bamboo, garden radish and matrimony vine are added thereto and allowed to be permeated by the refined wood vinegar. The tonic composition consequently produced, it has been demonstrated, far excells that which is obtained with a wood vinegar produced by using a smaller number of trees. 
     In preparing the comfrey leaves or a mixture containing a majority of comfrey leaves and supplementally incorporating leaves of bamboo, garden radish and matrimony vine, the amount of leaves to be added to the refined wood vinegar falls, in practice, in a range from about 0.1 to 10 parts by weight based on 100 parts by weight of the refined wood vinegar. It has been experimentally confirmed that if the amount is smaller than the lower limit, 0.1 part by weight, then the effect of the product fails to reach the desired level, and if the amount exceeds the upper limit 10 parts by weight, the leaves are wasted without bringing about any extra effect. It is preferable to use the comfrey leaves independently. If a mixture of leaves is used, the comfrey leaves preferably comprise as a large proportion as possible, for example not less than 90% by weight, to obtain the cellulase type crude enzyme. In the comfrey leaves, vitamine B 12 , vitamine B, allantoin, germanium, etc. are contained as active components. These components are permeated and dissolved by the refined wood vinegar and, therefore, produce useful functions on man and other animals. When a mixture of leaves is used, the proportions by weight of comfrey leaves and the leaves of bamboo, garden radish and matrimony vine are in the ranges of about 85-99% comfrey, about 0-15% bamboo, about 0-15% garden radish and about 0-15% matrimony vine. Desirably, the combined amount of the leaves of bamboo, garden radish and matrimony vine to be added to the comfrey leaves is such as to give a ratio by weight of about 1 to 100 of the comfrey leaves. 
     It is also possible to produce a granular or powdery solid tonic composition as illustrated in FIG. 1 by adding to the refined wood vinegar a soft amorphous carbon powder obtained for example by roasting bark and chips of deciduous trees or those of a mixture of about 90-99% of deciduous trees by weight and about 10-1% of coniferous trees by weight at about 350° C for about 20 to 500 hours, preferably for about 200 to 300 hours, crushing and acreening the obtained carbide. It is particularly desirable that the adsorption of the refined wood vinegar with carbon powder is carried out several times separated by drying. Although the most suitable temperature for the roasting is 350° C, the range of about 250° to 450° C suffices for the purpose. A desirable amount of soft amorphous carbon powder to be admixed is about two to six times, preferably about three to four times, the weight of the refined wood vinegar. When the tonic composition in the form of a granular or powdery solid is ingested into the system of man and other animals, the soft amorphous carbon powder serves to adsorb the gases of indole and skatole types generated in consequence of the hydrolysis of starches in the goods taken by man and other animals, and also functions to control the environment of microorganisms within the systems. The tonic composition in the form of a granular or powdery solid has various advantages such as being economical, facilitating its preservation and management, transportation and handling, and being easily added or admixed into animal feed. Incidentally, the deciduous trees or a mixture containing a major fraction of deciduous trees and a minor fraction of coniferous trees, which serve as the raw material for the soft amorphous carbon powder, are identical with those which are employed for the preparation of wood vinegar. The soft amorphous carbon powder obtained as described above is preferably finely divided to a particle diameter of not less than 300 mesh (ASTM E-11-61) for use by man. When it is intended for use by other animals, it is preferably divided into a particle diameter of the order of 100-300 mesh (ASTM E-11-61) to facilitate admixture with animal feed. Zeonerite can be used instead of the soft amorphous carbon powder without causing any change in the effects. 
     The tonic composition of the present invention as described above was found to have the following main properties and contents: 
     
         ______________________________________                                    
1.  Properties                                                            
    Specific gravity   0.98 to 1.01                                       
    pH                 3.5 to 4.18                                        
    Acidity (as acetic acid)                                              
                       0.80 to 1.30% by weight                            
2.  Composition                                                           
A)    Organic acids                                                       
      Acetic acid      0.46 to 0.47% by weight                            
      Propionic acid   0.30 to 0.31% by weight                            
      Valeric acid     0.14 to 0.15% by weight                            
      Other organic acids                                                 
                       0.30 to 0.29% by weight                            
B)    Weakly acidic compounds (about 0.21%)                               
      Guaiacol, ethyl guaiacol, paracresol, etc.                          
C)    Neutral components (0.02% by weight)                                
      Ketones - Acetone, methylethyl ketone, methylpropyl                 
      ketone and methylisopropyl ketone                                   
      Aldehydes - Acetaldehyde, isobutyl aldehyde,                        
      propionaldehyde, acryl aldehyde, butyl aldehyde,                    
      valeraldehyde and isovaleraldehyde, etc.                            
D)    Others (about 0.05% by weight)                                      
      Rare elements such as allantoin, vitamin B group,                   
      pure protein and germanium, etc.                                    
______________________________________                                    
 
    
     From the foregoing analysis, it is seen that the tonic composition is a liquid with a weakly acidic odor which contains numerous rare components other than organic components and exhibits catalytic action and pharmacological activities on living systems. 
     The tonic composition according to the present invention was further subjected to luminous spectroscopic analysis for determination of useful nutrient components for living organisms. The results of this analysis are shown in Table 1. 
     
                       Table 1                                                     
______________________________________                                    
     Wave-   Strength of             Strength of                          
Ele- length  Analytical Ele- Wavelength                                   
                                     Analytical                           
ment (in A)  line       ment (in A)  line                                 
______________________________________                                    
     3082    +               2516    +                                    
Al   3092    ++         Si   2524    +                                    
     2816    +               2881    +                                    
     3158    ++              3302    +                                    
Ca   3179    ++         Na                                                
     4226    +++             3303    +                                    
     4254    +               3009    +                                    
Cr   4274    +          Sn   3175    +                                    
     4289    +++             3262    ++                                   
     3247    +               2743    ++                                   
Cu                      Fe   2749    ++                                   
     3273    +               2755    ++                                   
     2795    ++              2794    +                                    
Mg   2802    ++         Mn   2798    +                                    
     2852    +               2801    +                                    
______________________________________                                    
 
    
     In the preceding table, the strength of the analytical line was rated by a scale, in which the symbols denote the following: 
     - Absence of discernible analytical line 
     ± Unclear analytical line 
     + Analytical line discernible 
     ++ Analytical line clearly observed 
     +++ Analytical line strongly observed 
     Analytical apparatus: EPART type emission spectroanalysis analyzer made by Shimadzu Seisakusho 
     Emission conditions: Electrode gap 3 mm, slit width 15 μ, excitation source DC Arc., current 5A, electrode emission graphite made by Hitachi Seisakusho, regular 5 mm Diam. 
     Wavelength range (measurement): 2000 to 4500 A, exposure time 45 sec. 
     The foregoing results indicate that the principal components of the tonic according to this invention are weakly acidic, account for 60% by weight of the dissolved components and are invariably utilized as substances belonging to the class of carbolic acids. Therefore, these components exhibit strong disinfecting, anticepticizing and deodorizing activities. Of the components, those of the pyrogallol type function most effectively as deodorants and also serve as insectifuges capable of paralyzing parasites (specifically tapeworms and roundworms) inhaviting in the living organisms. Of the secondary components, the neutral components account for only about 20% by weight. They are invariably carbonyl compounds (aldehydes and ketones). Among the aldehydes present, formaldehyde is contained at a concentration of only 6.0 ppm. 
     The detoxication action of the tonic composition prepared according to the present invention is hereinafter disclosed with reference to the changes in liver function of rats which were dosed by oral administration 
     Liver function examination often has been carried out to examine whether there is any liver trouble caused by a substance given. 
     Using Alkaline Phospha K-Test wako and S. TA-Test wako (serum transaninase) of Wako K.K., GOT (glutamic oxaloacetic transaminase), GPT (glutamic pyruvic transaminase) and alkali phosphatase were measured by giving the tonic composition to rats. The tonic composition of 1 ml/200g was given to rats for 14 days. This amount is 75 times the amount usually given to man. The test results are shown in the following table. 
     
                                           Table 2                                 
__________________________________________________________________________
Control group       Test group                                            
             Alkali              Alkali                                   
No. GPT GOT  phosphatase                                                  
                    No. GPT GOT  phosphatase                              
__________________________________________________________________________
1   41.0                                                                  
        160.0                                                             
             40.0   1   31.0                                              
                            102.0                                         
                                 17.0                                     
2   44.0                                                                  
        150.5                                                             
             120.0  2   29.0                                              
                            102.0                                         
                                 12.0                                     
3   33.0                                                                  
        132.0                                                             
             36.0   3   40.0                                              
                            133.0                                         
                                 105.0                                    
4   41.0                                                                  
        160.0                                                             
             25.0   4   40.0                                              
                            195.0                                         
                                 25.0                                     
5   31.0                                                                  
        160.0                                                             
             20.0   5   25.0                                              
                             67.0                                         
                                 30.0                                     
    38.0                                                                  
        152.5                                                             
             26.6       33.0                                              
                            119.8                                         
                                 37.8                                     
Aver-                                                                     
    Karmen                                                                
        Karmen      Aver-                                                 
                        Karmen                                            
                            Karmen                                        
age unit                                                                  
        unit K-A unit                                                     
                    age unit                                              
                            unit K-A unit                                 
__________________________________________________________________________
  Judging from the above, the tonic composition of the present invention
 seems not to cause any liver trouble. And considering the amount of the
 composition given to rats, this composition seems not to have toxicity.
 
    
     The tonic composition of the present invention, upon ingestion, manifests tonic properties. In particular it may be of assistance in the following circumstances: (1) alleviating constipation and abnormal corpulence, (2) assisting the gastrointestinal organs in their digestive and assimilative functions, (3) deodorizing the body, (4) assisting in the treatment of diabetes, (5) mitigating arthritis, and (6) invigorating the system. The tonic composition of the present invention is harmless to man and other animals and involves no secondary effects. 
     As for the manner of use, the recommended dosage for an adult man is about 3 to 4 cc of the tonic composition diluted with water to about 50 to 100 times the original volume, taken on two or three separate occasions per day. The dosage for an infant may be less than one third of that for the adult. 
     Biochemical blood tests and liver function tests were carried out after the oral administration of the present tonic composition produced by the method of the present invention. The test results are shown in the following table. The oral administration of the tonic composition for 1.5 months and 2 months respectively was observed to normalize transaminase of GOT and GPT. Also, there was observed a tendency to normalize blood sugar and blood pressure at the time with an empty stomach. And the test using a neurometer was also carried out to observe the efficacy of the tonic composition of the present invention. The results are also shown in Tables 3 and 4. 
     
                                           Table 3                                 
__________________________________________________________________________
                      33 year old male                                    
                      Decline of liver function                           
                      before                                              
                           72nd 119th                                     
                                     147th                                
BIOCHEMICAL BLOOD TEST                                                    
                      use  day  day  day                                  
__________________________________________________________________________
        Number of     491  476  490  390                                  
        red corpuscle                                                     
        Number of     5,600                                               
                           6,000                                          
                                5,300                                     
                                     4,800                                
        leucocytes                                                        
        Hemoglobin (g/dl)                                                 
                      14.7 14.6 15.0 12.3                                 
        Hematocrit (%)                                                    
                      43.2 42.6 44.6 35.8                                 
        Mean corpuscular                                                  
                      88   89   91   87                                   
        volume (μ3)                                                    
        Mean corpuscular                                                  
                      29.9 30.6 30.5 30.4                                 
        hemoglobin (μμg)                                            
        Mean corpuscular                                                  
                      34.3 34.1 34.0 34.6                                 
        hemoglobin con-                                                   
        centration (%)                                                    
        Stab form leuko-   7         3                                    
        cytes (%)                                                         
        Segmented leuko-   58        55                                   
hemogram                                                                  
        cytes (%)                                                         
        Lymphocytes (%)    31        32                                   
        Monocytes (%)      1         2                                    
        Eosinophilecytes (%)                                              
                           3         8                                    
        Basophiliecytes (%)                                               
                           0         0                                    
LIVER FUNCTION TEST                                                       
        Total bilirubin (mg/dl)                                           
                      0.9  0.7  0.6  0.9                                  
        Thymol TTT (U)                                                    
                      8    6    0.9  0.7                                  
        ALP (U)       12.3 12   7.7  5.8                                  
        GOT (U)       60   52   104  14                                   
        GPT (U)       45   40    69  6                                    
        LDH (U)       250  180  380  350                                  
        ChE (Δ pH)                                                  
                      2.0  1.2  1.5  1.4                                  
        Total cholesterol (mg/dl)                                         
                      235  220  190  200                                  
           35 year old male                                               
           hepatitis                                                      
157th 298th                                                               
           before                                                         
                36th 59th 93rd 128th                                      
                                    160th                                 
day   day  use  day  day  day  day  day                                   
__________________________________________________________________________
506   526  412  461  412  480  461  449                                   
4,600 6,100                                                               
           4,500                                                          
                4,600                                                     
                     3,900                                                
                          4,600                                           
                               4,200                                      
                                    5,600                                 
14.8  15.1 13.4 13.2 11.7 14.2 13.7 13.2                                  
42.5  43.4 40.8 40.4 35.4 43.5 41.4 36.1                                  
85    83   100  88   86   90   89   84                                    
29.3  28.5 32.7 28.5 28.3 29.8 29.6 29.2                                  
34.9  34.7 33.2 32.8 30.6 32.7 32.9 34.6                                  
      2    3    5    5    6    6    5                                     
      42   35   43   46   39   46   46                                    
      50   58   48   44   52   44   44                                    
      2    2    4    2    2    2    2                                     
      3    1    0    2    1    1    2                                     
      1    1    0    1    0    1    1                                     
0.7   0.5  1.2  1.2  1.3  0.8  1.6  1.8                                   
0.8   0.3  4    4    0.4  2    0.3  0.2                                   
6.8   8.8  13   4.9  4.3  4.8  4.0  4.5                                   
22    15   68   35   18   26   15   16                                    
13    6    45   25   7    15   8    8                                     
310   325  490  360  320  300  280  320                                   
0.8   1.2  1.1  1.0  1.0  0.8  0.9  1.0                                   
180   185  390  270  230  180  194  160                                   
          Normal value                                                    
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          ♀ 4.10 - 5.30 × 10.sup.4 ♂ 3.80 - 4.80        
          × 10.sup.4                                                
          4.0 - 8.5 × 10.sup.3                                      
          ♀ 14 - 18, ♀12 - 16                               
          ♀ 40 - 55, ♂ 37 - 47                                
          80 - 99                                                         
          27 - 31                                                         
          32 - 36                                                         
          3 - 6                                                           
          45 - 55                                                         
          25 - 40                                                         
          44 -6                                                           
          1 - 3                                                           
          0 - 1                                                           
          0.4 - 0.8                                                       
          less than 4                                                     
           4 - 12                                                         
          10 - 40                                                         
           8 - 30                                                         
           50 - 400                                                       
          0.8 - 1.1                                                       
          120 - 250                                                       
        Alubumin (%)  64.1 59.7 65.8                                      
        Globulin (%)  35.9 40.3 44.2                                      
Protein α.sub.1 (%)                                                 
                      3.1  4.8  4.7                                       
fraction                                                                  
        α.sub.2 (%)                                                 
                      7.0  12.7 8.2                                       
        β (%)    11.0 7.9  6.6                                       
        γ (%)   14.5 14.7 14.5                                      
        A/G           1.80 1.48 1.93                                      
        Maximum       50   30   30   20                                   
        Minimum       15   10   10   5                                    
        Average       33.7 19.4 19.4 10.6                                 
Neurometry                                                                
        +             3    2    2    1                                    
        0             19   22   22   23                                   
        -             2    0    0    0                                    
        Stability of autonomic                                            
        nerve                                                             
61.0 58.3 63.5  64.3      64.4 62.1 62.9                                  
39   41.7 36.5  35.7      35.6 37.9 37.1                                  
4.2  4.6  3.3   2.9       3.2  3.6  5.1                                   
9.3  9.6  11.3  9.0       9.6  11.1 9.7                                   
10.3 7.5  11.7  9.4       7.6  9.2  8.4                                   
15.0 19.8 10.0  14.1      15.0 13.8 13.7                                  
1.57 1.40 1.70  1.80      1.81 16.4 1.70                                  
20   10   140   80   30   20   20   20                                    
5    5    0     10   10   5    5    10                                    
12.1 10.5 31.6  37.5 17.5 10.8 10.6 22.1                                  
2    0    6     5    3    0    0    0                                     
21   24   8     15   21   23   24   24                                    
1    0    10    4    0    1    0    0                                     
          33    62   87   96   100  100                                   
                56.9 - 70.5                                               
                43.1 - 29.5                                               
                2.0 - 4.8                                                 
                 6.1 - 10.5                                               
                 6.7 - 10.3                                               
                 9.7 - 22.1                                               
                1.2 - 2.4                                                 
                20 - 24                                                   
__________________________________________________________________________
 
    
     
                                           Table 4                                 
__________________________________________________________________________
                                   76 year old                            
                                   female                                 
                     35 year old   hyperpiesia &amp;                          
                     male          liver function                         
                     acute hepatitis                                      
                                   depression                             
                     before after 1                                       
                                   before after                           
BIOCHEMICAL BLOOD TEST                                                    
                     use    month  use    month                           
__________________________________________________________________________
        Number of    449 × 10.sup.4                                 
                            461 × 10.sup.4                          
                                   438 × 10.sup.4                   
                                          437 × 10.sup.4            
        red corpuscle                                                     
        Number of    4,500  4,600  4,500  4,500                           
        leucocytes                                                        
        Hemoglobin (g/dl)                                                 
                     13.2   13.1   13.7   13.6                            
        Hematocrit (%)                                                    
                     39     40.4   40.6   40.9                            
        Mean corpuscular                                                  
                     85     88     92     93                              
        volume (μ3)                                                    
        Mean corpuscular                                                  
                     29.5   28.5   31.3   31.3                            
        hemoglobin (μμg)                                            
        Mean corpuscular                                                  
                     34     32.8   33.9   33.4                            
        hemoglobin con-                                                   
        centration (%)                                                    
        Stab form leuko-                                                  
                     5      5      4      4                               
        cytes (%)                                                         
        Segmented leuko-                                                  
                     47     43     45     46                              
        cytes (%)                                                         
Hemogram                                                                  
        Lymphocytes (%)                                                   
                     45     48     55     46                              
        Monocytes (%)                                                     
                     2      4      5      2                               
        Eosinophilecytes (%)                                              
                     1      0      1      2                               
        Basophiliecytes (%)                                               
                     0      0      0      0                               
LIVER FUNCTION TEST                                                       
        Total bilirubin (mg/dl)                                           
                    1.0     1.2    0.7    0.4                             
        Thymol TTT (U)                                                    
                    9       4      6      3                               
        ALP (U)     19.5    4.9    15.2   5.3                             
        GOT (U)     75      35     67     11                              
        GPT (U)     62      25     45     5                               
        LDH (U)     520     360    200    180                             
        ChE (ΔpH)                                                   
                    1.1     1.1    1.1    0.9                             
        Total cholesterol                                                 
                    390     250    200    180                             
        (mg/dl)                                                           
42 year old   67 year old                                                 
male          male                                                        
diabetes      hypertension                                                
before 2 months                                                           
              before 1.5 months                                           
use    later  use    later  Normal value                                  
__________________________________________________________________________
484 × 10.sup.4                                                      
       509 × 10.sup.4                                               
              467 × 10.sup.4                                        
                     437 × 10.sup.4                                 
                            ♀(4.0-5.3) × 10.sup.4,           
                            ♂(3.8-4.5) × 10.sup.4              
5,200  7,900  8,600  5,400  (4.0 - 4.5) × 10.sup.3                  
14.2   15.1   13.9   13.9   ♀14 - 18, ♂ 12 - 16               
41.9   45.3   43     42     ♀40 - 55, ♂ 37 - 47               
87     89     94     96     80 - 99                                       
29.4   29.8   30.9   31.9   27 - 31                                       
34.1   33.9   32.6   33.1   32 - 36                                       
2      5      4      5      3 - 6                                         
47     53     60     45     45 - 55                                       
47     37     33     48     25 - 40                                       
3      2      2      2      4 - 6                                         
0      3      1      0      1 - 3                                         
0      0      0      0      0 - 1                                         
0.8    0.6    0.8    0.6    0.4 - 0.8                                     
0.5    0.4    4      1.2    less than 4                                   
6.3    5.6    12.5   9.7    2.7 - 10                                      
72     31     57     17     10 - 40                                       
57     28     45     9       8 - 30                                       
310    280    300    350     50 - 400                                     
0.9    1.1    0.8    1.0    0.8 - 1.1                                     
244    200    230    210    120 - 250                                     
            Albumin (%)  63.5 64.3 56.2 54.3                              
            Globulin (%) 36.5 35.7 43.8 41.1                              
            α.sub.1 (%)                                             
                         3.3  2.9  4.3  5.3                               
Protein     α.sub.2 (%)                                             
                         11.3 9.0  11.1 10.6                              
fraction    β (%)   11.7 9.4  16.7 14.9                              
            γ  (%) 10.0 14.1 1.3  1.4                               
            A/G          1.7  1.8  1.3  1.4                               
Others      Fixed quantity of                                             
when        blood sugar (mg/dl)                                           
hungry      Blood pressure (Max.)                                         
            (mmHg)                                                        
            (Min.)                                                        
            Maximum      130  140  40   30                                
            Minimum      0    10   0    10                                
Neurometry  Average      16.6 32.1 12.3 25.6                              
            +            3    3    7    1                                 
            0            1    15   10   22                                
            -            20   6    7    1                                 
          58.8 55.6 60.7 59.5 56.9 - 70.5                                 
          41.2 44.4 39.3 40.5 43.1 - 29.5                                 
          3.8  5.5  4.1  4.8  2.0 - 4.8                                   
          11.0 12.3 7.5  9.6   6.1 - 10.5                                 
          13.1 10.8 11.7 10.4  6.7 - 10.3                                 
          13.1 15.5 15.8 15.7  9.7 - 22.1                                 
          1.4  1.3  1.5  1.5  1.1 - 1.7                                   
          120  100            less than 100                               
          130  120  180  160  120 - 150                                   
          80   80   120  100  70 - 90                                     
          40   50   100  30   40 ± 10                                  
          0    5    0    10   20 ± 10                                  
          5.9  9    33.7 25.6 40 ± 10                                  
          3    1    8    1    0 - 2                                       
          11   21   4    22   20 - 24                                     
          10   2    12   1    0 - 2                                       
__________________________________________________________________________
 Note:                                                                    
 By means of Neurometer, autonomic nerves can be examined, so that it can 
 be known in a short period of time whether one is healthy, in poor health
 or ill.                                                                  
 Note:                                                                    
 TTT = Thymol turbidity test                                              
 ALP = Alkaline phosthatase                                               
 LDH = lactic dehydrogenase                                               
 ChE = Cholinesterase                                                     
 
    
     Health means the stable state of the automatic nervous system of the whole body. When one is ill, the degree of autonomic imbalance is strong. 
     FIG. 2 is a graph of data measured by neurometer, showing the improvement of the automatic nerve stability rate of a patient who took the tonic composition of the present invention. The stability rate is gradually approaches 100% from the average 50% as the days go by. In taking the tonic composition produced by the method of this invention, clinical efficacy, neurometry for the presence of an adverse reaction and close hematological examination are parts of experiment carried out along with various function tests. 
     FIG. 3 shows the shifting of the serum enzyme activity value (liver function test LDH) by the administration of the tonic composition. This proves that the value is moving into the health zone as time goes by. 
     FIG. 4 shows also the result of liver function test GOT by the administration of the tonic composition and proves that the activity value is moving into the health zone as time goes by. 
     FIG. 5 shows the result of liver function test GPT by the administration of the tonic composition and proves that the value is moving into the health zone as time goes by. 
     FIG. 6 shows improvement of the stability rate of the autonomic nervous system (measured by neurometer) by the efficacy of the tonic composition. This FIG. 6 includes 25 cases and each case improved its stability to cross over the health line of 80% as time goes by. 
     Further, when the tonic composition of the present invention is used for 30 - 40 days, about 90% of cases go beyond the health line. 
     In the use of the tonic composition for animals, it has been experimentally confirmed that the tonic added at a weight ratio of about 1 to 100 of the feed produces the best results. The assortment of effects which the tonic composition of this invention brings about in the systems of domestic animals, e.g. pigs, hens, cattle, trout and eels, and may be summarized as follows: (1) It encourages and promotes enzymatic activities within the various internal organs, (2) provides specific pharmacological functions, (3) provides a specific deodorizing effect, (4) produces no secondary effect in prolonged usage, (5) does no harm to animals, (6) comforts the tips of teats, (7) alleviates skin diseases, (8) assists in easy delivery of offspring, (9) increases the digestive and assimilative ability and consequently decreases the residual protein content in faeces to a great extent, (10) lowers the nitrogen content in the faeces to provide increased fertilizing effect and (11) contributes to the organic stratification of soil. Specifically, in the case of pigs, the tonic provides rapid deodorization of the pigs&#39; bodies and their faeces, promotes their growth, encourages the pigs&#39; liking for feed, heightens the feed efficiency (accelerates the rate of body weight increase), activates and promotes the various functions of the internal organs, promotes the efficiency of disposal of soil and gives many benefits with small expense entailed. In the case of raising chickens for broilers the tonic stops the objectionable odor of the chicken house, encourages the chickens&#39;  liking for feed, improves the feed efficiency and activates the functions of the internal organs to provide added resistance to diseases. In the case of raising hens for producing eggs, the tonic improves the quality and the taste of eggs laid and heightens the egg-laying ratio in addition to the effects described above in connection with chicken raising. In the case of raising cattle for dairy products and meat, the tonic improves the quality of milk, the quality of meat and the taste of related products besides the same effects as mentioned above. In the case of raising fish (e.g. eels and trout) the tonic ensures well-balanced fish growth, improves the fishes+ liking for feed, heightens the feed efficiency, and activates the functions of the internal organs and gives added resistance to diseases. 
     The reaction of the tonic composition upon the living bodies of animals other than man is such as to manifest direct, pronounced effects unlike those produced on the human system. First, the tonic permits the living bodies of animals to acquire surprisingly high resistance to diseases and renders the administration of medicines unnecessary. As to the improvement in business economy, the tonic provides more than 10% by weight savings in feed, and improved the well-balanced growth and body weight increase as well as the quality of meat and eggs, and enhances the taste of products. In the case of the human system, balanced enrichment of the constitution and caloric value of the food ingested are improved by the tonic to give much enhanced vitality as compared with the human system prior to the use of the tonic. Thus, the use of the tonic enriches the physical strength, normalizes the constitution and gradually builds up strong resistance to diseases. The enzymatic activities brought about by the ingestion of the tonic composition of this invention assists in the creation of the cells immunized to diseases. 
     As described above, the tonic composition according to this invention is effective in promoting the health of the human system. This is because the tonic alkalinizes and consequently cleans the blood. The active component of the tonic composition is contained in the form of acetic acid in a concentration of about 1 to 3% by weight. From the standpoint of chemical reaction, therefore, it naturally produces an acidic reaction. Physiologically, however, it produces an alkaline reaction. It is because of this principal component that the tonic balances the pH status of the body fluid and provides effective recovery from fatigue. Within the systems of animals, the acetic acid has an important part to play, in conjunction with lactic acid and propionic acid, in the formation of milk fats from carbohydrates and fats. Thus, the tonic makes a great contribution to the improvement of the quality of milk, particularly of milk fats. 
     The invention is further illustrated by the following Examples and tests involving the use of the tonic composition according to this invention. 
     EXAMPLE 1 
     In a kiln built of bricks and having an area of about 5.2m × 4.6m and a height of 1m, amorphous carbon and wood vinegar were obtained by carbonizing and roasting, for 240 hours at the temperature range from 300° to 350° C, barks and chips of various trees such as Akagashi (Quercus acuta Thunb), Shirogashi (Quercus myrsinaefolia Blume), Aragashi (Quercus glauca Thunb.), Ichiigashi (Quercus gilva Blume), Kojii (Shiia cuspidata Makino), Itajii (Shiia Sieboldii Makino), Shiratabu (Litsea glauca Sieb.), Benitabu (Machilus Thunbergii Sieb.), Camphore tree (Cinnamonum Camphora Sieb.), Wild cherry tree (Pronus donarium Sieb. var. spontanea Makino), Yusu (Distylum racemosum Sieb. et Zucc.), Beech (Quercus serrata Thunb.), Kunugi (Quercus acutissimia Carruth), Japanese Oak (Fagus crenate Blume), Hombeam (Carpinus laxiflora Blume), Mizume (Betula grossa Sieb. et Zucc.), Maple tree (Acer plamatum Thunb.), Zelkova tree (Zelkova serrata Makino), Myrica (Myrica rubra Sieb. et Zucc.), Scabu (Euphorbia pekinensis Rupr. var. japonensis Makino), Harigiri (Kalopanax septemlobus Koidz.), Shemp nut (Pterocarya rhoifolia Sieb. et Zucc.), Walnut (Juglans mandshurica Maxim. var. Sieboldiana Makino), Camellia (Camellia japonica L.), Himeshara (Stewartia monadelpha Sieb. et Zucc.), Oak (Quercus dentata Thunb.), Wax tree (Rhus succedanea L.), Japanese cedar (Cryptomeria japonica D. Don), Ground-cypress (Chamaecyparis obtusa Endl.), Pine tree (Pinus Thunbergii Part.), Hemlock spruce (Tsuga Sieboldii Carr.) and White fir (Abies firma Sieb. et Zucc). The wood vinegar thus produced was filtered to remove tars and allowed to stand at rest in a storage tank for 5 years. The supernatant layer formed in the wood vinegar after standing was removed and filtered. The filtrate (refined wood vinegar) was added to benzene in a volume ratio of 10 parts of wood vinegar to 2.5 parts of benzene and then agitated. The upper layer of the agitated solution was removed and the bottom layer was transferred into another container. This procedure was carried out 2 or 3 times. The wood vinegar consequently obtained was placed in a container and heated to about 40° C to drive off benzene. 
     This refined wood vinegar was further distilled to remove about 0.5 - 10% of a fraction having a low boiling point of not more than 100° C at normal pressure and about 10 - 15% of a fraction at not less than 103° C at normal pressure. Thus, about 72% of the refined wood vinegar was obtained. This refined wood vinegar was thus repeatedly distilled until no formaldehyde, 1-3 benzpyrene and others came to be detected. Comfrey leaves were permeated in this refined wood vinegar at a volume ratio of 1 part of comfrey leaves to 100 parts of the refined wood vinegar to disperse the component of the comfrey leaves into the refined wood vinegar. And the resultant refined wood vinegar was filtered to produce the tonic composition for man and other animals. 
     The tonic composition for man and other animals obtained according to Example 1 has the following main ingredients. 
     
         ______________________________________                                    
Mineral ingredients                                                       
Potassium             1.5 ppm                                             
Calcium               1.3 ppm                                             
Magnesium             0.2 ppm                                             
Iron                  1.6 ppm                                             
Allantoin             1.31 ppm                                            
Pure protein          0.03 %                                              
Vitamin B.sub.2       0.02 mg%                                            
Vitamin B.sub.12      0.2 mμ/ml                                        
Germanium             1.86 ppm                                            
Acid degree         0.86%                                                 
pH                  3.7                                                   
______________________________________                                    
 
    
     The tonic composition according to this invention exhibits a deodorizing effect because the aforementioned weakly acidic components such as cresol and paracresol interact to remove odors. These components, when absorbed within living systems, are converted into weakly acidic components and, in that form, are effective to remove odors. Further, while the organic substances are undergoing fermentation in a digesting tank or cesspool, the enzyme components cause catalytic reactions and diffusing actions to enhance the deodorizing activity. In this case, other components synergistically act with these components to make some contribution to the deodorizing effect. 
     EXAMPLE 2 
     The procedure of Example 1 was repeated, except that 97% comfrey leaves, 1% bamboo leaves, 1% garden radish leaves and 1% matrimony vine leaves were used instead of comfrey leaves. 
     The tonic composition for man and other animals obtained according to Example 2 has the following main ingredients. 
     
         ______________________________________                                    
Mineral ingredients                                                       
Potassium             1.0 ppm                                             
Calcium               1.3 ppm                                             
Magnesium             0.1 ppm                                             
Manganese             0.2 ppm                                             
Silicone              2.0 ppm                                             
Phosphorus            2.7 ppm                                             
Iron                  1.2 ppm                                             
Allantoin             0.3 ppm                                             
Pure protein          0.01 %                                              
Vitamin B.sub.2       0.1 mg%                                             
Vitamin B.sub.12      0.1 mμ/ml                                        
Germanium             0.4 ppm                                             
Acid degree         0.4 %                                                 
pH                  3.5                                                   
______________________________________                                    
 
    
     EXAMPLE 3 
     The liquid tonic composition obtained in Example 1 was added, in three split fractions, each of about 30% by weight, to a soft amorphous carbon powder of a particle diameter not larger than 300 mesh (ASTM E-11-61) and dried to produce a tonic composition for human use. This soft amorphous carbon powder was obtained by causing the same barks and chips of the trees as used in Example 1 to be carbonized at 350° C for 240 hours in a kiln having an area of about 5.20 m × 4.60 m and a depth of 1 m and finely dividing the resultant carbonization product to a particle diameter finer than 300 mesh (ASTM E-11-61) by means of a pulverizer. 
     The ingredients of the tonic composition for man and other animals obtained was observed containing 13.5% soft amorphous carbon powder other than those contained in the tonic composition produced according to Example 1. 
     EXAMPLE 4 
     The procedure of Example 3 was repeated, except that the soft amorphous carbon powder had a particle diameter in the range of 150 to 200 mesh (ASTM E-11-61). Thus was obtained a tonic composition for animal use. 
     EXAMPLE 5 
     Dried comfrey leaves were added to the refined wood vinegar obtained in Example 1 at a ratio of 1 part of comfrey leaves to 100 parts of the aforesaid refined wood vinegar and allowed to stand at rest therein for four months. Thereafter, it was treated by repeating the procedure of Example 1. 
     Clinical data and tests on the use of the tonic composition according to this invention will be described herein below. 
     CLINICAL DATA 1: 
     A male patient 32 years old who vomited and had epigastrum pain and anorexia since the beginning of October, 1974 went to a hospital and was diagonosed as having a gastric ulcer by a Rontgen examination of the stomach. 
     In this case, the liquid composition of Example 1 was used and he stopped taking other medicaments. The composition of 1.0cc was given to him 3 to 4 times a day. The total amount of the composition given was 3.0 - 4.0cc per day. Said symptoms were comparatively alleviated and the pain disappeared within about 10 days of the first application of the composition. Successively, he took the liquid composition of 1.0 cc 3 times a day. After about one month, the symptoms disappeared, so that when he had a Rontgen examination of the stomach it was diagnosed that the gastric ulcer had almost cured. 
     CLINICAL DATA 2: 
     A female patient 40 years old had had lumbago in the balance for a few years. Her symptoms became bad in September, 1974. After a Rontgen examination at a hospital she was diagnosed as having apondyolisthesis. She had received various medical treatments there, but no sign of recovery was seen. 
     1.0cc of the inventive composition was given her prior to each meal 3 times a day. On the 7th day, lambago began to be cured little by little. During the above period obstipation was cured. On the 14th day lumbago was almost cured, and she could lead an ordinary life. And anorexia disappeared. When 4 weeks had past, disorders of menstruation became normal, and lumbago and constipation were cured. 
     CLINICAL DATA 3: 
     Dr. K, a pediatrician practicing in Kita-ku, Osaka City, was attacked by a sudden appearance of hematuria in January, 1972. Upon examination of his system, the Urological Department of Kyoto University Hospital diagnosed his case to be tuberculosis of both kidneys, with the right kidney completely deprived of its function and the left kidney complicated by renal calculus. In January, 1973, he underwent a surgical operation for extirpation of his kidney. In February of the same year, he underwent another surgical lithotomy for granulation of renal calculus. For a short time that followed, his disease appeared to be alleviated. In September of that year, however, adhesive closure occured in the ureter extending from the remaining left kidney to the bladder. He was immediately sent to the hospital and operated upon for nephrophthisis. Having a catheter inserted through the left abdominal region into the bladder and a urinary bag attached to the external end of said catheter, he was barely saved from the crisis. He was no longer able to rely on the antitubercular agent which he had customarily been taking since the onset of the disease because of side effects of the agent. 
     In the early part of December of the same year, he was informed of the high efficacy of the product of the present invention and began to take it in the form of internal medicine which was prepared according to Example 1. From the third day, the urine became nearly transparent and he felt energy return spontaneously. On the seventh day, he could go by himself to Kyoto University Hospital. As a result of various examinations, the hospital assured him that the remaining kidney had been incredibly improved in its excretory function. 
     Dr. K is said to enjoy steady recovery from the disease and consequently started consulting his patients every other day in April, 1973. 
     CLINICAL DATA 4: 
     Mrs. S, a 41-year-old housewife and mother of two children, is a sister-in-law of Mr. T, a friend of mine. She lives in the suberb of Osaka City. Four years ago, she suffered from gastritis and gastroptosis and received about a half year&#39;s medical treatment. She faithfully dieted on boiled unpolished rice and was completely cured of the disease. Two years ago, she gave up the diet and began to take polished rice and nutritious food in the hope of putting on weight. As a result, she came to enjoy target proportions of 50 Kg of weight to 150 cm of height. In the early part of May 1975, she experienced serious hematemesis all of a sudden and fell unconscious. She was carried by ambulance to a hospital, where the examination showed her blood pressure to have fallen so heavily that with the physical strength remaining in her system, she could not have a surgical operation. Mr. T and his wife came to seek advice on March 6 and told that she was barely surviving due solely to blood transfusions. 
     Mrs. T flew to Osaka, taking two week&#39;s doses of the aqueous product of Example 2 and the powder product of Example 3. She cared for the patient, making a cream of boiled unpolished rice and encouraging the patient to take it. Mrs. T is quoted as admitting that her purpose of the visit was to persuade the patient and her husband into refusing to receive a surgical operation even if she regained her physical strength sufficiently. 
     Several days later, Mrs. T was informed that her sister had regained physical strength sufficiently that the scheduled surgical operation would be performed on the evening of March 12. Mrs. T once again went to Osaka and asked the physician in charge to postpone the operation by one month. After the patient had completed the second 2 week&#39;s doses of the medicine, her gastric system was given an elaborate examination by means of X-ray equipment and a gastric camera. The examination failed to detect any trace of ulcer. The physician is said to admit that he has never experienced such a miraculous efficacy of a medicine. 
     Admittedly there are cases in which the X-ray examination fails to detect any hemorrhagic region in stomaches which have experienced ulcerous hemorrhage. In any event, the present case ought to be regarded as that of an exceptional success in consideration of the fact that an abdominal operation was obviated. 
     Test 1: Use of the tonic in chicken-raising 
     150 young hens raised for egg-laying for 60 days after their birth, were given a feed containing the tonic composition of Example 1 (liquid) in an amount of 1 cc per day per hen for 150 days. The hens started laying eggs 25 days, on the average, earlier than other hens which were given a feed not containing the tonic composition of this invention. None of the hens suffered from disease and the odor of the faeces was reduced to a remarkable extent. 
     Test 2 
     The tonic composition (liquid) produced by the method of Example 2 was given to one group of chinkens for broilers and not given to another group for comparison of growth ratio, weight increase ratio, feed efficiency, limb meat yield and regular meat yield. The results as shown in Tables 5 and 6 indicate the following facts. 
     1. Growth ratio: For the first 56 days, the growth ratio was 100% for both the groups, with no difference. The growth ratio for the first 70 days was 100% for the test group and 98.6% for the control group respectively in the case of the chickens of Group A. In the case of the Group B, the growth ratio was 100% for both groups. ##EQU1## 2. Weight increase ratio: Weight increase ratios during the ages of 11 days and 56 days and between those of 56 days and 70 days were as shown in the table. 
     3. Feed efficiency: The feed efficiency was 0.1 lower for the test group than for the control group. ##EQU2## 4. Lamb meat yield: No discernible difference was observed between the two groups. For the comparison, limb meat was taken from all chickens of each group. 
     5, Regular meat yield: For comparison, the meat taken from 5 chickens of each sex. The regular meat was taken from 2 chickens of each sex. 
     
                                           Table 5                                 
__________________________________________________________________________
Classification         Test group      Control group                      
Species                Group A Group B Group A Group B                    
Sex                    ♀                                           
                           ♂                                         
                               ♀                                   
                                   ♂                                 
                                       ♀                           
                                           ♂                         
                                               ♀                   
                                                   ♂                 
__________________________________________________________________________
Number of birds to which feeding was                                      
                       31  39  28  26  34  36  28  26                     
started                                                                   
Number of birds which underwent test                                      
                       31  39  28  26  33  36  28  26                     
Growth ratio %          100     100    98.6     100                       
Average weight (Kg)                                                       
            70 days                                                       
                  Average                                                 
                       2.48    2.49    2.34    2.48                       
and standard                                                              
            of age                                                        
                  X--  2.818                                              
                           2.140                                          
                               2.830                                      
                                   2.148                                  
                                       2.663                              
                                           2.012                          
                                               2.789                      
                                                   2.163                  
deviation         S D   .163                                              
                            .124                                          
                                .212                                      
                                    .215                                  
                                        .238                              
                                            .142                          
                                                .235                      
                                                    .178                  
            56 days of age                                                
                       2.24            2.34                               
Feed efficiency                                                           
            70 days of age                                                
                       2.57            2.67                               
Limb meat yield, %     75.4    75.2    74.4    75.3                       
Regular mat yield, %   30.3    32.0    39.4    30.0                       
__________________________________________________________________________
 
    
     
                                           Table 6                                 
__________________________________________________________________________
Weight increase (average/bird, in g)                                      
     Period  Ages of Ages of Ages of                                      
Group        11 - 56 days                                                 
                     11 - 70 days                                         
                             56 - 70 days                                 
__________________________________________________________________________
A ♀                                                                
     Test group                                                           
             1.888   2.653   765                                          
     Control group                                                        
             1.791   2.493   702                                          
     Index   (105)   (106)   (109)                                        
A ♂                                                                  
     Test group                                                           
             1.454   1.985   531                                          
     Control group                                                        
             1.397   1.856   459                                          
     Index   (104)   (107)   (116)                                        
B ♀                                                                
     Test group                                                           
             1.867   2.662   795                                          
     Control group                                                        
             1.908   2.623   715                                          
     Index    (98)   (101)   (111)                                        
B ♂                                                                  
     Test group                                                           
             1.478   1.988   510                                          
     Control group                                                        
             1.512   2.006   494                                          
     Index    (98)    (99)   (103)                                        
__________________________________________________________________________
 
    
     
         ______________________________________                                    
Remarks: The indexes given in parentheses indicated weight                
increasess for given test groups calculated by assuming                   
weight increases for corresponding control groups as                      
100 respectively.                                                         
Materials and method:                                                     
Chickens used in test - A total of 248 chicks (for broilers)              
hatched on 18 July 1971                                                   
Test period - 70 days following start of feeding                          
Test grouping                                                             
          Number of birds to                                              
                          Daily dose in water                             
          which feeding was                                               
                          (per bird/day)                                  
          started                                                         
Test group                                                                
          124 (with agent added)                                          
                          11 to 30 days of                                
                          age - 0.2 ml                                    
                          31 to 70 days of                                
                          age - 0.4 ml                                    
Control group                                                             
          124 (no agent added)                                            
Management of raising                                                     
              The chickens were all raised in                             
              a windowed chicken house with                               
              a ground-level floor.                                       
Feed                                                                      
Between ages of 0 and 28 days -                                           
              commercially available feed                                 
              formulated for young broilers,                              
              23 - 76.                                                    
              Between ages of 28 and 70 days -                            
              commercially available feed                                 
              formulated for broilers of                                  
              advanced growth stage, 20 - 80.                             
______________________________________                                    
 
    
     Test 3 (Use of tonic in pig raising) 
     For 100 days, 48 pigs having an average weight of 40 kg were fed on a feed prepared by adding to leftovers the tonic composition (liquid) of Example 1 in an amount corresponding to 1% based on said leftovers. Compared with a group of pigs fed on the same leftovers omitting the addition of the tonic composition, the pigs of the test group showed healthful growth, accelerated body weight increase by an average of 15%, complete freedom from disease, improved quality of meat (thin fat layers), decreased body odor and sharply reduced faecal odor. 
     An anatomical observation performed on the pigs failed to detect occurences of round-worms within the intestinal interior. The intestines from the pigs of the test group were found to be very resilient. 
     Test 4: 
     The tonic composition (liquid) prepared according to Example 2 was used in pig raising to determine what effect the addition thereof would bring about in removing objectional odor and in improving the efficiency of pig raising. The results of the comparative study are shown in the following Table 7. 
     
                                           Table 7                                 
__________________________________________________________________________
          Control group             Test group                            
                Number                   Number                           
                of                       of                               
Grouping  Date  pigs                                                      
                    Weight                                                
                          Remarks   Date pigs Weight                      
                                                   Remarks                
__________________________________________________________________________
Young pigs                                                                
          Jul. 26,                                                        
                9                   Jul. 26,                              
                                          9                               
purchased 1970                      1970                                  
Test started                                                              
          Aug. 1,                                                         
                9   401.9           Aug. 1,                               
                                          9   385.3                       
          1970                      1970                                  
Average body                                                              
          Aug. 1,   44.6            Aug. 1,   42.8 Though a symptom       
weight    1970                      1970           resembling SEP         
                                                   appeared, it showed    
Contraction of                                                            
          Aug. 22,                                                        
                1         Medicine for             little sign of         
disease   1970            SEP given                progress and was       
                                                   cured without use      
Fatality  Aug. 29,                                                        
                1   48.0                           of any medicine.       
          1970                                                            
Contraction of                                                            
          Aug. 22,                                                        
                1         Medicine for                                    
disease   1970            SEP given                                       
Shipment of ill                                                           
          Oct. 13,                                                        
                (1) (52.0)                                                
pig       1970                                                            
Contraction of                                                            
          Sep. 20                                                         
                1         Medicine for                                    
disease   1970            toxo. given                                     
Fatality  Sep. 22,                                                        
                1   66                                                    
          1970                                                            
Feed                2435.0                    2635.0                      
Feed efficiency     3.3                       3.1                         
Shipment  Oct. 13,        One ill pig,                                    
          1970            52 K included                                   
          Nov. 4,                   Nov. 4,    851.5                      
                                                   No pigs dead           
          1970            Two pigs, 108                                   
                                    1970                                  
          Nov. 23,                                                        
                7   728.5 K met death                                     
          1970                                                            
Objectional odor          Objectionable            Very little odor       
                          odor persisted           remained.              
                                                   Body odor hardly       
                                                   perceivable.           
__________________________________________________________________________
 Note:                                                                    
 The tonic composition was added in an amount corresponding to 1/100 of th
 feed.                                                                    
 &#34;Sep&#34; stands for swine enzootic pneumonia.                               
 &#34;toxo&#34; stands for toxoplasmosis.                                         
 Used medicines are Aurofac, Tephpare and Tyrocine.                       
 
    
     From the preceding results, the following facts have been brought to light. 
     1. The objectional odor was nearly completely absent. The pigs&#39; bodies hardly smelled offensive. The objectionable odor began to decline about one week after start of the use of the tonic. 
     2. As regards the efficiency of growth, when pigs were divided into the control group and the test group at the start, there was difference of about 1.8 kg of average weight. Apparently, the pigs of the control group were quite healthy and at first showed more appetite for the feed than those of the test group. 
     3. Among the pigs of the test group, a symptom resembling SEP was observed in one pig. The pig, with no medicine administered, was placed under careful observation. The disease developed very little. The pig recovered health in 3 days. 
     4. No medicine of any sort was administered to the pigs of the test group. 
     5. In the control group of pigs which at first enjoyed healthful growth, 3 pigs contracted diseases (2 pigs died and one pig was shipped out to the meat market). 
     6. A larger weight increase was shown despite a smaller feed requirement (less by 0.2 kg). 
     7. Absence of contraction of disease indicates that the pigs acquired increased resistance to disease. 
     8. The fixed consumption of the tonic at the pig farm (capacity for 420 pigs) was roughly 340 liters (kg) (17 cases) (bags). 
     9. The results indicate that consumption of the agent is enough to ensure ideal pig growth and thorough elimination of the objectional odor. 
     Test 5 
     The tonic consumption (liquid) according to Example 1 was used in raising pigs (Berkshire). A feed having the tonic incorporated by an amount of 1/100 of the amount of feed and a feed omitting the addition of the tonic were tested to determine what effect the use of the tonic would bring about in improving the growth efficiency and the removal of offensive odor. The results of the comparison are shown in the following Table 8. 
     
                                           Table 8                                 
__________________________________________________________________________
                           Weight                                         
                                 Number of                                
                    Average                                               
                           at time                                        
                                 round worms                              
           Feed efficiency                                                
                    daily weight                                          
                           of    within                                   
Group Division                                                            
           (20 - 90 kg)                                                   
                    increase                                              
                           slaughter                                      
                                 intestines                               
__________________________________________________________________________
      Control                                                             
           3.50     559    79  kg                                         
                                 2                                        
Group A                                                                   
      Test 3.45     566    82    1                                        
      Control                                                             
           3.28     617    84    6                                        
Group B                                                                   
      Test 3.17     636    87    0                                        
__________________________________________________________________________
 (Note)                                                                   
 Species of pigs used in test - Berkshire                                 
 Amount of tonic used - 1/100 of feed                                     
 Period of test - four months                                             
 
    
     Growth efficiency (test group with feed incorporating tonic - improved and accelerated growth). 
     1. Feed incorporating the tonic encouraged the pigs&#39; liking for the feed, with their appetite particularly heightened during the body weight stage of 50 to 90kg. 
     2. The feed requirement was smaller for the test group (using the feed incorporating the tonic) than for the control group. Nevertheless, the average daily weight increase was greater for the test group than for the control group. 
     3. The weight at the time of slaughter was greater for the test group than for the control group. Deodorizing effect -- This effect was conspicuous. 
     1. Offensive excrement and body odor were hardly perceivable. 
     2. During dissection, no offensive odor emanated from the interior of the intestines. 
     Occurrence of round-worms at the time of dissection; 
     In the pigs of the control group, an average of 8 round-worms was observed in the intestines. In those of the test group, the average was 1 round-worm. 
     Test 6 
     When the tonic consumption (powder) according to Example 4 was used on hens raised in a chicken farm (egg-laying), it served to remove the offensive odor of hens&#39; droppings improve the egg quality and heighten the survival ratio and feed efficiency. The results are compared in the following tables 9 and 10 with the results obtained for the control group. 
     
                       Table 9                                                     
______________________________________                                    
        Number of hens                                                    
                     Ratio of                                             
Group   used in test addition  Remarks                                    
______________________________________                                    
Control  99          0                                                    
Test    100          1%        Test for one month                         
______________________________________                                    
 (Note) Species of hen - Decarb 371                                       
 
    
     
                                           Table 10                                
__________________________________________________________________________
Item        Test group                                                    
                    Control group                                         
                            Remark                                        
__________________________________________________________________________
Number of hens                                                            
            100     99                                                    
Survival ratio                                                            
            99    % 100   % One hen died                                  
                            of intestinal                                 
                            inflammation                                  
Total hen days                                                            
            2,999   2,970                                                 
Number of eggs laid                                                       
            2,230   2,176                                                 
Egg weight  121,360                                                       
                  g 116,790                                               
                          g                                               
Average egg weight                                                        
            54.4  g 53.7  g                                               
Egg-laying ratio                                                          
            74.4  % 73.3  %                                               
Average egg yield                                                         
            40.5  g 39.3  g                                               
Feed consumption                                                          
            291,900                                                       
                  g 341,100                                               
                          g                                               
Average daily feed                                                        
            97.3  g 114.8 g                                               
consumption                                                               
Feed efficiency                                                           
            2.41    2.92                                                  
Thickness                                                                 
      Dull end                                                            
            0.401   0.361                                                 
of egg                                                                    
      Equinox                                                             
            0.374   0.353                                                 
shell Sharp end                                                           
            0.414   0.381                                                 
__________________________________________________________________________
 
    
     The preceding test data indicate the following facts: 
     1. Survival ratio -- No significant difference was observed between the test group and the control group. 
     2. Egg-laying ratio -- the egg-laying ratio was 1.1% higher for the test group than for the control group. 
     3. Average egg weight -- The average egg weight was 0.7 g heavier for the test group than for the control group. 
     4. Average daily egg yield per hen -- The test group showed an increase of 1.2 g of yield over that of the control group. 
     5. Average feed consumption per hen per day -- The control group consumed 17.5 g more than the test group. 
     6. Feed efficiency -- The test group showed an efficiency 0.51 higher than that of the control group. 
     7. Test of egg quality 
     a. The Haugh unit was height of egg content after breaking shell-better in the test group than in the control group. 
     b. The shell thickness was greater for the test group than for the control group. The shell thickness was particularly large at the sharp end, followed by the dull end and the equinox. 
     8. Economy -- The profit was  18 per hen greater for the test group than for the control group. 
     9. Condition of offensive odor -- The usual odor on a chicken farm persisted in the control group, while practically no odor was perceivable in the test group. 
     Through the tests described above, it has been ascertained that the addition of the tonic composition according to this invention, when given to domestic animals, encourages the animals&#39; liking for their feed, promotes the health and growth of animals, prevents diseases, deodorizes their faeces and bodies, and serves effectively in improving the hygienic condition of their environment. The tonic composition prepared in the form of a granular or powdery solid adsorbed on a soft amorphous carbon powder is as effective as the liquid tonic described above. Moreover, the soft amorphous carbon powder, when introduced into the internal systems of the animals, serves to adsorb gases of indole and skatole type occurring as a consequence of the hydrolysis of starch present in the animals&#39; feed and at the same time functions to control the environment of micro-organisms within their systems.