Method of repelling insects by systemic action in humans on sulfur and sulfur containing substances
OBJECT OF THE INVENTION 
     An object of the invention is to create a human body condition which is repellent to insects by introducing sulfur or sulfur combined or mixed with other substances into the body. 
     Another object is to provide humans with prolonged protection from insects by administering dosages of sulfur or sulfur combined or mixed with other substances. 
     Another object is to create a skin condition in humans which is repugnant to biting or sucking insects such as chiggers, mosquitoes, flies, etc. by ingesting sulfur or sulfur combined or mixed with other substances. 
     Another object is to create a mucous membrane condition that is repugnant to biting, sucking or chewing insects. 
     Another object is to create the repugnant condition in either the skin or mucous membrances by introducing the sulfur or sulfur combined or mixed with other substances into the body by using a rectal suppository or by injecting the condition-creating substance directly into the tissues. 
     There has been a long-felt need for a systemic insect repellent by many people such as hunters, fishermen, the military and agricultural and construction workers who spend prolonged periods in an outdoors environment infested with biting, sucking, or chewing insects. Heretofore, the common available relief was in the form of pesticides which could be painted or dusted upon the exposed body portions. 
     Systemic insecticides are not unknown and have been used in plants, for example: U.S. Pat. No. 3,793,452 discloses the systemic application of a compound or mixture of compounds which, when applied to the roots of growing plants, are translocated through the plants to render the plants toxic to sucking or chewing insects. 
    
    
     It is comtemplated by this specification and claims that, through the intake of sulfur, sulfur mixture or sulfur compounds into the body orally, by suppository or by injection into the tissues, the component of perspiration or saliva containing sulfur is increased to a degree whereby the secretions from the glands of the skin and mucous membranes become repellent to biting, sucking or chewing insects, e.g. mosquitoes, chiggers, ticks, etc., and that by maintaining a reduced dosage the repellent effect is continued. 
     Examples of materials which produce this result when ingested are flowers of sulfur (S); mixture of sulfur (S) and charcoal (C); mixture of sulfur (S) and cream of tartar; (KHC 4  H 4  O 6 ); edible sulfates; sulfides, except those of poisonous heavy metals, etc. The dosage is maintained below the limits at which sulfur produces a laxative or cathartic effect. 
     It has been found that a tablet of a mixture of 5 grains of sulfur or 5 plus 1 grain of KHC 4  H 4  O 6  taken three times daily over a period of several days produces the repellent effect and reducing the dosage to twice daily will maintain the repellent indefinitely. 
     The same is true of a tablet containing a mixture of sulfur (S) and carbon (C) and substantially the same dosage is effective. 
     When suppositories are used a soluble sulfate may be suspended in a vehicle such as glycerine of cocoa butter and the dosage would be as much as five times the concentration as that when ingested. 
     All dosages, however have to be related to the height, weight, and skin pigmentation and overall health of the subject. 
     The systemic metabolism of S in the human body is such that it appears in the saliva as sulfocyanates, e.g. KSCN, and in secretions from the cutaneous glands (sweat or perspiration) which by analyses contain among other substances, K 2  SO 4 , Na 2  SO 4 , NH 4  HSO 4 , H 2  S and CH 3  SH. 
     By increasing the intake of elemental sulfur or sulfur compounds it appears that there is an increase in the sulfur products occuring in the excretions from the skin and mucous membranes and that by controlled dosage the level is increased to a degree whereby sucking, biting and chewing insects are repelled, but the cathartic actions of the sulfur products is avoided. It appears that the mixture of sulfur and cream of tartar is the preferred embodiment since cream of tartar has a mild diaphoretic effect. It also appears desirable that the compounds ingested should be metabolized by the human body to produce compounds in the sweat and saliva that have relatively high vapor pressures, such as hydrogen sulfide (H 2  S) and methylthioalcohol (CH 3  SH), at the body and air temperature at which the sucking and biting insects may be present. 
     Although the present invention has been described with preferred embodiments, it is to be understood that variations and modifications may be resorted to, without departing from the spirit and scope of this invention, as those skilled in the art will readily understand. Such modifications and variations are considered to be within the purview and scope of the appended claims.