Commercial Fixed Wing
Flight Crew Air Transport Pilot (ATP); Flight Crew Instrument; Flight Crew Multiengine
Communication Breakdown; Confusion; Situational Awareness; Time Pressure
ATC Issue All Types; Deviation / Discrepancy - Procedural Published Material / Policy
Air Traffic Control Issued New Clearance; Flight Crew Rejected Takeoff; General Flight Cancelled / Delayed
Procedure
Just clearing the bridge prior to Taxiway 1 we were cleared for takeoff Runway ZZR at approximately XA00z for an on-time departure.  After brake release and prior to 80 knots our takeoff clearance was canceled.  We aborted departed [Taxiway] 1X and were instructed to hold short of [Taxiway] 1Y for 45 minutes both engines running (vaccine on board) and wait for departure control to resume duty (allegedly COVID cleaning).Tower and ATC need to coordinate their operations.  We shouldn't be getting a takeoff clearance cancellation after brake release.  Over 80 knots we may have had to press anyway as opposed to a high-speed abort putting everyone in a precarious position.  Since company is the only significant operation during the AM push in ZZZ there isn't any legitimate reason ATC isn't aware and able to accommodate our operations.
Air carrier Captain reported performing an aborted takeoff after getting takeoff clearance cancelled during the initial roll.