A320
Flight Crew Last 90 Days 250; Flight Crew Total 10000; Flight Crew Type 4500
Fatigue
Other fatigue
Flight Crew Took Evasive Action; General Work Refused
Company Policy; Human Factors
I was on my 8th day in a row away from home; two 4-day trips back-to-back; each with 30+ hour layovers that arrived late on day 1 and departed early on day 3; which puts my body clock out of whack. Predawn hotel pickup; the Captain and I both missed the correct altimeter setting on the before start checklist and the revised route on the PDC; even though I picked up the PDC and read it; which is my standard technique. We discovered the altimeter error on taxi-out and the PDC revision on departure; when Departure cleared us to a fix that was not programmed in the FMGC. We both removed ourselves from the remainder of the trip due to fatigue.
An A320 First Officer reported that he and the Captain removed themselves from a trip fatigued because the four day trip upset their circadian rhythm and they were making too many errors.