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spec: Regarding the note in bold at the bottom of the major and minor proposals , there could be only 6 here . The major hormones modulating linear growth ( growth hormone , thyroid hormones and gonadal steroids ) have different effects on bone maturation . '' I believe that , without a profoundly humbling experience-and for some this requires extremely humiliating circumstances-the chances of real change are negligible . Their review of the major rheumatic diseases integrates the cellular , biochemical , and molecular biological mechanisms that are important in rheumatic disease pathogenesis . The author of the ICC analysis , Julian Kassum , commented : '' Nobody should play down the poverty that afflicts so much of the developing world . Read full story . The various provisions of the CFS described above have made a major contribution in this regard . One change is that both the major and minor proposals now say that two courses used to fulfill requirements in another major or minor may count toward meeting requirements of the LACA major or minor . '' and gleefully goes on with her day . During a hearing on Sudan in June 2002 , he angered some members of the House International Relations Committee by dismissing their support for sanctions that would have barred oil companies operating in Sudan from raising capital or trading stock in the United States . Our regional staff is prepared to work with recipients to help them meet their obligations under Title VI . " The award was established to honor those who have made a major contribution to the field of human-computer interaction .