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spec: `` But given the curious lack of facts and figures on the tips of their tongues , one wonders if these tough guys know anything about the art of negotiation , or if they merely play negotiators on TV. Only one thing seems certain to everyone '' in the know `` : If these strikes do happen , they will affect the personal checking accounts of almost everyone in town a fact that has powerless nobodies across the nation daydreaming about all those overstuffed couches and 3x5 ' Toulouse-Lautrec prints they've spotted in InStyle magazine being auctioned off to the highest bidder . Boards in Mexico " have been a status thing rather than a working thing , " says Roderick Reinhart , who spent two years teaching and consulting there . At the other extreme , though , Sheehan 's syndrome and other forms of hypopituitarism can cause an adrenal crisis -- a sudden , potentially fatal undersupply of the hormone cortisol . This is the earliest substantial literary manuscript ever acquired by the Library , and was the basis of the definitive edition produced by Colin Roderick in 1953 . `` We may debate it , but we're not going to end up answering yes , that 's for sure , '' said Cooper . Thomas Pavel has written extensively on poetics , linguistics , and narratology . Representative examples ( with the names of the major collaborators provided in parenthesis ) include studies of control of the cystic fibrosis transmembrane conductance regulator ( CFTR ) chloride channel structure and function by phosphorylation , dephosphorylation and ATP hydrolysis ( David Gadsby and Angus Nairn ) ; new methods for dissecting the molecular machinery of nucleocytoplasmic transport ( Michael Rout and Michael Matunis ) ; cell cycle control in budding yeast and the elucidation of substrates of the major cyclin-dependent kinase in yeast ( Frederick Cross and Michael Rout ) ; studies of the pathogenic protozoan Trypanosoma brucei ( George Cross ) ; studies aimed at understanding the molecular mechanisms controlling development and dysfunction of the mammalian cerebellum ( Nathaniel Heintz ) ; studies of eukaryotic gene expression and transcription ( Robert Roeder ) ; characterization of expression of proteins in the erythrocyte plasma membrane that are encoded by the malaria parasite Plasmodium falciparum ( Sanford Simon and Sanjay Desai ) ; investigations of STAT proteins and transciptional regulation ( James Darnell ) ; identification of the protein components of human telomeres ( Titia de Lange ) ; elucidating the molecular mechanism of transmembrane signal transduction by G protein-coupled receptors ( Thomas Sakmar ) ; defining the network of WW domain signaling in yeast ( Marius Sudol ) ; understanding the role of opioid receptor systems in addiction and analgesia ( Mary Jeanne Kreek ) ; and studies aimed at elucidating the structure and function of ion channels ( Roderick MacKinnon ) . The strongest correlate of an affirmative response was having a history of tobacco use . Whether he is writing about historical legacy or his own back yard , Roderick has arrived at a voice of distinct solitariness and precise observation .