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spec: The resources listed below will get you started . Although a full accounting of the physical basis for the concurrent conformational rigidification and destabilization at low pH requires further investigation , the high level of detail in the MD simulations provides a potential molecular mechanism : the breaking of the hydrogen bond between the side chains of Asp46 and Arg53 , and changes in electrostatic interactions , appear to allow the binding loop to move closer to the core part of the protein , resulting in a more compact structure at low pH . Therefore , this course should include the application of organic principles to molecular biology , drug design , and consumer products . She also carefully checked through all my documentation , handed it back to me , turned to her computer and asked , '' Name ? Yet , in the six years since the first edition of Human Blood Groups was published , new blood groups have been discovered , several blood group genes have been cloned , and the molecular backgrounds of numerous blood group variants have been worked out . Early years spent exploring genome sequencing for the Neurospora crassa fungus in the Neurospora Genome Project helped Platero realize her own interest in the realm of research , especially in molecular biology . `` It was an exceptionally hot and humid East Coast kind of day when Rachel Jakubovitz dressed up like a fish to work the crowds at the New Jersey Festival of Ballooning in Readington . Dr. Wallace and colleagues are interested in elucidating the cellular and molecular mechanisms by which agrin directs the postsynaptic cell to make a synapse in the right place and at the right time . Most recently , we reported on the challenges that the Government Printing Office faces and identified options for the future , focusing on electronic dissemination rather than printing .