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spec: This is particularly true when considering refinement alternatives since they are often techniques which are not specific to particular research or teaching goals and are not necessarily found in discipline-specific literature . The exceptions are ( 1 ) bookkeeping of local work each time a choicepoint is created , ( 2 ) testing for signals at predicate calls , and ( 3 ) synchronizing with other workers when taking work from a shared ( public ) choicepoint . New components in the eighth competition include a Data Management Core , a Sickle Cell Research Scholars Program , and optional pilot projects for promising , but untested , innovative research . '' Serious people want serious agents . Since influenza peaks most often in January and February , vaccination is encouraged through the winter months . Because these ocular events may occur in conjunction with other disease states , a visual exam prior to initiation of combination REBETOL / INTRON A therapy is recommended in patients with diabetes mellitus or hypertension . This disability has been misunderstood for hundreds of years , but it affects more men then women and it often runs in the family . This process often creates further damage to the relationship between parents , and this , in turn , can be traumatic for , and detrimental to children . Having said all that , anyone who has chosen to do a Ph.D. and is thinking about academia will already be aware of the main attractions ; the opportunity and challenge to tackle hard problems and discover something completely new and interesting ( and maybe even useful !