there is still no evidence to base interventions on neuropsychological rehabilitation or cognitive stimulation related with learning development . this is not derived at all from a lack of studies but to methodological difficulties finding trials suitable for meta - analysis . this is a real hazard for translational research because of the difficulties of developers in testing new designs and showing efficacy , and also for the development of the body of knowledge , making difficult to find main theories and design appropriate experiments . advances in communication technologies allow delivery of intensive , personalized , monitored neuropsychological intervention , through telerehabilitation platforms , and cognitive neuroscience based content , to guide plastic changes towards the recovery of more appropriate behaviour . advances in information technologies have provide new possibilities to assess efficacy , opening new pathways to knowledge discovery from databases generated from clinical practice . institute guttmann , from its initiative previrnec , is pioneering the application of this dual approach , bridging knowledge to the end user through communication technologies ( internet ) and extracting implicit knowledge ( efficacy on neuropsychological rehabilitation ) from data generated from each intervention .