the aim of this study was to identify the definition , therapeutics , and mechanism of diabetes from the resources of itm in order to provide new recommendations for the treatment of diabetes . we searched therapeutic itm books such as exir - e - aazam , tibib - e - akbari , as well as material medical itm books such as makhzan - ol - advieh and tohfat - ol - momenin to find topics on ziabites . we also searched sciencedirect and pubmed databases with keywords  herbal medicine  and  diabetes  to confirm the effectiveness of the reported methods . we also determined that there were different mechanisms and dosage forms for the management of ziabites . the number of materials related to ziabites mechanisms in makhzan - ul - adwiah was 138 . for instance , asperugo procumbens amplifies liver and cucurbita maxima diminish kidney temperature . forms of administration recommended in eksir - e - aazam include oral , inhalation , rectal and topical ; among which oral and inhalation have been verified by conventional medicine . we also found articles that substantiated the antidiabetic effect of some medicinal herbs mentioned in exir - e - aazam . there are several forms of administration recommended in itm for the treatment of diabetes , which have not been used in conventional medicine . therefore , further studies are required to substantiate their effects scientifically in order to develop new effective drugs .