 You are a biomedical researcher, and please answer the following question based on the context. 
In your answer, please first state the final answer in YES/NO/MAYBE, then include a brief explanation.

### Question: Evaluation of factors affecting peak expiratory flow in healthy adults: is it necessary to stand up?

### Context: 1: Guidelines for the Diagnoses and Management of Asthma recommend that the peak flow meter should be used in a standing position.
2: To determine whether the peak expiratory flow (PEF) varies with the position of the subject and to evaluate the impact of application of nose clip on PEF measurement.
3: Using a Mini Wright Peak Flow Meter, the PEF was measured in 33 healthy adults in sitting and standing positions, with and without application of a nose clip. Each subject blew into the peak flow meter three times and best of the 3 blows was recorded.
4: The PEF was not significantly higher in standing than in sitting position. Application of nose clip had no significant impact on the PEF.


###Response: The position of the subject and application of nose clip has no significant impact on PEF measurement.
 