dental implantation is considered as one of the most widely employed procedures in dental practice . even though biocompatible osseointegrated dental materials are used for fabrication of dental implant moreover , placement of dental implants in the maxilla may be complicated by certain anatomical landmarks such as the nasopalatine duct , maxillary sinus , and nasal cavity . nasopalatine duct cyst ( npdc ) is an intraosseous developmental nonodontogenic cyst in the midline of the anterior palate . the etiology of npdc is unknown , but the possible causes may include local trauma , infection , and spontaneous proliferation . the cone beam computerized tomography ( cbct ) with its potential for 3d ct - based surgical planning and measurement helps in the evaluation of the nasopalatine canal dimensions before any surgical procedures in this region . it has been reported that cbct is superior to the conventional ct in that it reduces the size of the irradiated area of the patient and it has higher image accuracy . the aim of this study was to highlight the development of npdc after the placement of dental implants . a literature search was carried out in march 2015 using medline , accessed via the national library of medicine pubmed interface , embase , and cochrane library databases , searching for articles , published in english , relating the development of npdc after the placement of dental implants . we used a combination of the following keywords : nasopalatine duct cyst , nonodontogenic cyst , developmental cyst , and dental implants . we also used the  related article feature  of pubmed to identify further references of interest within the primary search . these references were obtained , and their bibliographies and pertinent secondary references were also identified and acquired . all evaluated studies should involve the occurrence of npdc in relation to the dental implant placement . all studies that do not support the occurrence of npdc after the placement of dental implants should be excluded . all evaluated studies should involve the occurrence of npdc in relation to the dental implant placement . all studies that do not support the occurrence of npdc after the placement of dental implants should be excluded . only four articles were identified related to the occurrence of npdc after the placement of dental implants in the literature published in english . all of these articles were case reports [ table 1 ] . table 1 demonstrates some details about each case that included preoperative radiographs , preoperative condition of the site of implant placement , type of the implant used ( either immediate or delayed ) , the period from placement of implant till discovery of the lesion , cyst treatment , and the postoperative clinical outcomes . although the etiology of npdc is not clear as per yet , it may result from spontaneous proliferation of embryonic tissues remnants . also , it has been attributed to some factors including local trauma , poorly fitting dentures , and local infection . npdc is usually asymptomatic and it appears radiographically as a heart - shaped radiolucency due to the superimposition of the nasal spine and the resistance of the adjacent roots . as a treatment protocol , marsupialization alone may be sufficient in small lesions , but in case of large lesions marsupialization should be followed by cystectomy and autogenous bone grafting . to our knowledge , this is the first review reporting npdc cases after the placement of dental implants . the bone on the implant surface was not lost due to infection , but as a by - product of the expansive nature of the npdc in that area . the author proposed that with the removal of this expansive force induced by the npdc , the bone - implant contact could be restored , though he did not explain clearly the possible relation between the formation of npdc in reference to the placement of dental implant . reported a case of a 45-year - old male patient , who received an implant in the maxillary left central incisor due to root fracture . unfortunately , an asymptomatic oval - shaped radiolucency surrounding the apical area of the implant was revealed , even though there was no special finding in the physical condition of the patient . the authors suggested that the nasopalatine duct was traumatized or at least part of the canal was anteriorly positioned during the osteotomy procedures for dental implant . they postulated that the previously mentioned trauma stimulated the development of the npdc as indicated by brode and araiche . the immediate implant was placed after extraction of a tooth in an alveolus contaminated by prior endodontic infection , following careful curettage and debridement . they suggested that the placement of dental implant in the area with a preexisting infection could have facilitated the secondary bone infection . reported a case of npdc that occurred following the placement of two dental implants positioned 4 years after the teeth extraction without any previous local endodontic pathology or radiolucency . they concluded that the occurrence of npdc maybe correlated with implant surgery , because surgery is considered a possible irritant cause . from the literature , the development of npdc following the placement of dental implant maybe related to some factors , such as local trauma during surgical procedures , which may traumatize the nasopalatine duct and the presence of infection at the time of implantation . therefore , critical selection of appropriate cases as well as the use of cbct views to visualize the exact position of the nasopalatine duct is of great importance in order to avoid the development of such complications . the authors declare that there is no conflict of interests regarding the publication of this paper . the authors declare that there is no conflict of interests regarding the publication of this paper .