Isabella complied, sailing to Canada in 1843 to visit the Macphersons in Kingston, Ontario, as well as the Macdonalds. It was on this trip that after a few months courting, they were engaged and finally married on September 1, 1843, at the home of her sister, Maria and brother-in-law John Alexander Macpherson with the Rev. Mr. Machar of St. Andrew's Presbyterian Church (Kingston, Ontario)officiating. The couple were related by sharing their maternal grandmother; cousin marriage was not uncommon at the time. They lived together in Kingston. Although the marriage got off to a good start, Isabella realized her husband's main interests were business and human anatomy. Isabella bore two sons with John. The first was named John, born in New York in August 1847.
Isabella complied, sailing to Canada in 1843 to visit the Macphersons in Kingston, Ontario, as well as the Macdonalds. It was on this trip that after a few months courting, they were engaged and finally married on September 1, 1843, at the home of her sister, Maria and brother-in-law John Alexander Macpherson with the Rev. Mr. Machar of St. Andrew's Presbyterian Church (Kingston, Ontario) officiating. The couple were related by sharing their maternal parent; cousin marriage was not uncommon at the time. They lived together in Kingston. Although the marriage got off to a good start, Isabella realized her husband's main interests were business and human anatomy. Isabella bore two sons with John. The first was named John, born in New York in August 1847.