She is thought to have been interested in religion: a German psalm, «Gott ist mein Heil, mein Hülf und Trost», is believed to have been written by her. Sophie became queen consort of Denmark and Norway upon the ascension of her spouse to the throne in 1523. She was crowned 13 August 1525. At her coronation, she was granted Lolland and Falster, the castles in Kiel and Plön, and several villages in Holstein for her income. In 1526, Anne Meinstrup was appointed head lady-in-waiting for her court. Queen Sophie did not live at the Danish court as queen, but resided separated from her spouse on her property in Kiel, and treated her estates as her private independent fiefs, which caused disagreements with her spouse during his reign. The conflicts continued during the reign of his successors and until her death. In 1533, she became a widow and moved to Gottorp Castle with her children, awaiting the outcome of the election of the new king. During the Count's Feud 1533–36, her estates was occupied. In 1538, the new king asked her to leave Gottorp because of the costs and reside in Kiel.
She is thought to have been interested in religion: a German psalm, «Gott ist mein Heil, mein Hülf und Trost», is believed to have been written by her. Sophie became queen consort of Denmark and Norway upon the ascension of her spouse to the throne in 1523. She was crowned 13 August 1525. At her coronation, she was granted Lolland and Falster, the castles in Kiel and Plön, and several villages in Holstein for her income. In 1526, Anne Meinstrup was appointed head lady-in-waiting for her court. Queen Sophie did not live at the Danish court as queen, but resided separated from her spouse on her property in Kiel, and treated her estates as her private independent fiefs, which caused disagreements with her spouse during his reign. The conflicts continued during the reign of his successors and until her death. In 1533, she became a widow and moved to Gottorp Castle with her children, awaiting the outcome of the election of the new king. During the Count's Feud 1533–36, her estates was occupied. In 1538, the new queen asked her to leave Gottorp because of the costs and reside in Kiel.