the problems discussed above , inherent in the current whole - leaf process , have been solved in the embodiments of the present invention pertains , in one aspect , to a bifurcated method to process an aloe whole leaf . the present invention of the bifurcated whole - leaf process can preserve most of the bioactive chemical entities and components naturally present in the aloe whole leaf . as used herein , the term &# 34 ; bioactive &# 34 ; means &# 34 ; possessing biological activity ,&# 34 ; such as a pharmacological or a therapeutic activity . more specifically , the biological activity can be : analgesic ; antiviral ; anti - inflammatory ; antineoplastic ; immune stimulating ; immune modulating ; adjuvant ; or a combination thereof . a substance has an &# 34 ; analgesic &# 34 ; activity if it can relief pain . an &# 34 ; antiviral &# 34 ; activity is the activity of a substance that can interfere directly or indirectly with the replication of a virion or its infection and / or interaction with a host cell . a substance has an &# 34 ; anti - inflammatory &# 34 ; activity if the substance can inhibit the inflammatory process of heat , redness , swelling , pain and loss of function as a result of tissue destructive processes and response . an &# 34 ; antineoplastic &# 34 ; activity is the activity of a substance that can interfere with the cell cycle of tumor cells , that can prevent replication or repair of tumor cells , or that can increase programmed cell death or apoptosis , and / or effect the immunogenicity of tumor cells resulting in their destruction . a substance has an &# 34 ; immune stimulating &# 34 ; activity if the substance can stimulate the immune system by either promoting cytokine release from macrophages , increase specific , or non - specific , phagocytosis , and / or stimulate directly or indirectly the components of the host defense system . a substance has an &# 34 ; immune modulating &# 34 ; activity if the substance can interact with the immune system to either up - regulate ( enhance ) or down - regulate ( lessen ) the immune response . a substance has an &# 34 ; adjuvant &# 34 ; activity if the substance can enhance , non - specifically , the immune response to an antigen . a substance is also known to have an &# 34 ; adjuvant &# 34 ; activity if the substance , when added , can assist a drug in a formulation to hasten or increase the action of the principal ingredient of the drug . the bioactive chemical entities or components can be one or more chemical substances , or mixtures of different chemical substances , which chemical substances or mixtures thereof possess biological activity or activities . such chemical substances could include a moiety such as an organic acid , protein , amino acid , carbohydrate , peptide , glycoprotein , sterol , other organic / inorganic substances , and mixtures thereof . the word &# 34 ; bifurcated &# 34 ; is used to denote that each of the aloe fillet and the aloe rind is first processed separately . aloe gel fillet that is substantially anthraquinone - free can be produced by the following steps from a leaf of an aloe plant : 1 . washing the aloe leaf in a bactericidal solution to remove substantially all surface dirt and bacteria ; 2 . removing at least a first end portion from the washed leaf ; 3 . draining , preserving and collecting anthraquinone rich sap from the cut and washed leaf ; and 4 . removing rind from the leaf to produce a substantially anthraquinone - free gel fillet . aloe raw gel , &# 34 ; raw gel ,&# 34 ; or &# 34 ; aloe juice &# 34 ; that is substantially anthraquinone - free having solubilized and suspended matter can be obtained by grinding and homogenizing the substantially anthraquinone - free aloe gel fillet . each of the different methods set forth above uses the aloe fillet only . invariably , the rind is discarded before processing . the present invention , however , pertains to a bifurcated method to process the aloe whole leaf . in the present invention , the rind is not discarded . rather , the rind is separately processed to yield a liquid rind product . the fillet is also separately processed which yields a liquid fillet product . the liquid rind product and the liquid fillet product are then combined for further use , such as for beverages , food additives , cosmetic , and others . the bifurcated method to process the aloe whole leaf help to preserve and retain most of the bioactive chemical entities and components naturally present in the aloe whole leaf . broadly , one embodiment of the present invention pertains to a bifurcated method for processing an aloe whole leaf comprising : ( a ) washing the aloe whole leaf to give a cleaned aloe whole leaf ; ( b ) separating rind from the cleaned aloe whole leaf to produce a fillet ; ( ii ) removing coarse fibers from the ground fillet to give a relatively fiber - free fillet liquid ; ( iii ) homogenizing the relatively fiber - free fillet liquid to give a homogenized fillet liquid ; ( iv ) stabilizing the homogenized fillet liquid with a preservative to give a stabilized fillet liquid ; ( ii ) adjusting total solid content of the chopped rinds with water to give an adjusted rind solid mixture ; ( iii ) grinding the adjusted total solid mixture to give a ground adjusted rind solid mixture ; ( iv ) removing coarse fibers from the ground adjusted rind solid mixture to give a relatively fiber - free rind liquid ; ( v ) homogenizing the relatively fiber - free rind liquid to give a homogenized rind liquid ; ( vi ) reducing anthraquinone present in the homogenized rind liquid to give a rind liquid relatively free of anthraquinone ; ( vii ) sterilizing the rind liquid relatively free of anthraquinone to give a sterilized rind liquid ; ( viii ) stabilizing the sterilized rind liquid with a preservative to give a stabilized rind liquid ; and fig1 shows one embodiment of the present invention and it involves the following steps : aloe vera leaves arrive from the farm are soaked in water and rinsed with high pressure water jets to remove dirt and other foreign materials . aloe vera leaves are then placed in a water flume having water that typically contains about 200 ppm chlorine . typical residence time is about 30 minutes . as leaves enter the processing plant , they are sprayed with water to remove excess chlorine water . rind , thorns , tips and bases of the aloe leaves are removed , preferably manually , leaving two products : ( 1 ) the aloe vera fillets ( about 30 - 50 % w / w ); and ( 2 ) rinds , tips , bases and thorns , collected together and hereinafter called &# 34 ; rind .&# 34 ; at this step , the incoming material is rinsed with clean water to remove residue chlorine and other operation where the rinds are grounded by a cutting - action machine . the machine used here is constructed of food grade stainless steel and after the material passes through this step , is size is reduced to from about 0 . 1 mm to about 15 mm in size , preferably from about 0 . 1 mm to about 5 mm in size , and more preferably from about 0 . 2 mm to about 1 mm in size . at this step , aqueous liquid is added if needed to adjust the total solid content . the total solid content , as expressed by the refractive index , must be in a range from about 1 . 2500 to about 1 . 4500 , preferably from about 1 . 3000 to about 1 . 4000 , more preferably from about 1 . 3200 to about 1 . 3500 , and even more preferably from about 1 . 3350 to about 1 . 3355 . at this step , the rind fraction is grounded further to yield a mixture of chunks having particle size smaller than about 2 mm , and more preferably smaller than about 1 mm . at this step , the rinds fraction undergoes a coarse filtration with a maximum particle size of about 500 mm . the solid cake , the plant fiber , is discarded and the filtrate liquid is used for the subsequent steps . here the liquid is passed through a metal mesh ( about 5 micrometers ) at high pressure ( about 1500 psi ) to break any aggregates that occur in the aloe vera liquid . the purpose of this step is to reduce the viscosity of the liquid by mechanical means while preserving the chemical integrity of the liquid . the resulting liquid is treated with activated charcoal , preferably granulated with average particle size of about 1 . 5 mm . the liquid and the activated charcoal mixture is then stirred for a period of time , usually aobut 10 minutes . the amount of activated charcoal used ranges from about 0 . 5 to about 3 kgs per about 400 liters of aloe rind liquid . at this step , the mixture of aloe rind liquid and activated charcoal is filtered using a # 2 standard filter bags with pore size of about 300 - 50 um . the preferred pore size is aobut 100 um . then the resulting filtered liquid is passed through a second filtration step using bags with a pore size of about 50 - 5 um . the preferred pore size is about 10 um . a filter press could also be used utilizing the same rages of particle sizes . the liquid is then pumped through a high temperature short time sterilizer (&# 34 ; htst &# 34 ;) which elevates the temperature of the fluid to about 100 degrees c . the liquid is kept at this temperature for about 30 seconds , then cooled to about 20 degrees c . the cycle is repeated 2 to 5 times , but a single cycle can be sufficient . at this point , a preservative or a mixture of preservatives is added to the liquid . examples of preservatives include sodium benzoate , potassium sorbate , citric acid , and vitamin e . preferably , a mixture of about 0 . 08 % of sodium benzoate and about 0 . 15 % of citric acid is used , the citric acid used is enough to stabilize the ph at about 3 . 4 . further , the amount of water from the combined stabilized fillet liquid and stabilized rind liquid can be reduce to yield a syrup or even freeze dried to produce a powder . the resultant product can be used for beverages , food additives , cosmetics , and others . flavoring agents that can be used include vanilla , cinnamon oil , and others . various modifications of the disclosed processes to produce whole leaf aloe products , as well as alternative modifications , variations and equivalents will become apparent to persons skilled in the art upon reading the above general description of the preferred embodiment . the foregoing general description is not intended to limit the scope of the appended claims , which cover any such modifications , equivalents or variations .
a bifurcated method to process an aloe whole leaf by processing the aloe fillet and the aloe rind separately and subsequently combine the products from these separate processes , and the use of the final combined product .