the present invention sets forth systems for detecting when a nerve is near or adjacent to an electrified surgical tool , probe , cannula , or other surgical instrument . the present invention also involves optional systems for simultaneously determining the “ status ” ( e . g . : sensitivity ) of a plurality of nerves . as will be explained , the present system involves applying a signal with a current level to a probe near a nerve and determining whether an electromyographic “ emg ” ( i . e . : neuro - muscular ) response for a muscle coupled to the nerve is present . in preferred aspects , the present system applies a signal with a known current level ( ma ) to a “ probe ” ( which could be midline probe , a cannula , a needle , etc .) depending on the current level , distance to the nerve , and health of the nerve , an emg may be detected in a muscle coupled to the nerve . in accordance with preferred aspects , an emg response is determined to have been detected when the peak - to - peak response of the emg signal is greater than some level ( mvolts ). in other words , an emg response is determined to have been detected when the stimulus current level generates an emg having a peak - to - peak value greater than a pre - determined level ( for example , 60 mv or 80 mv in spinal nerve applications .) such stimulus current level at which an emg response is detected is termed the “ onset ” current level for the nerve . in optional aspects , the present invention also sets forth systems for determining these onset current values ( i . e . : determining the stimulus current level at which an emg response is detected with a maximum peak - to - peak value greater than a predetermined level ). such onset values may be determined for a plurality of nerves either in absolute terms , or in relation to one another . the first aspect of the present invention involves nerve detection . in the optional second aspect of the invention , nerve status information may be used to aid nerve detection . the nerve status aspect determines the minimum current level of a signal applied to a probe near a nerve needed to generate onset emg response for a muscle coupled to a nerve of interest . the present invention may use this determined minimum current level when determining whether a probe is near the same nerve . in optional aspects , the present invention may involve determining an initial set of “ baseline ” neuro - muscular response onset values for a plurality of different spinal nerve pathways . this optional second ( nerve status ) aspect of the present invention is preferably carried out prior to the first ( nerve detection ) aspect of the invention , with the initial set of “ baseline ” neuro - muscular onset values then optionally being used in the nerve detection function , as will be explained below . as the optional second aspect of the invention is carried out prior to carrying out the first aspect of the invention , it will be described first . in the nerve status determination , the minimum current level of a signal applied to a probe needed to generate an onset neuro - muscular response ( i . e . : emg response ) is first determined for each of a plurality of nerves , as follows . referring to fig1 , a patient &# 39 ; s vertebrae l1 , l2 , l3 , l4 , l5 , and s1 are shown . in a preferred aspect of the present invention , a portion of the patient &# 39 ; s cauda equina is stimulated ( i . e . depolarized ). this depolarization of a portion of the patient &# 39 ; s cauda equina may be achieved by conducting a stimulus pulse having a known current level between an epidural stimulating electrode 11 and a patient return electrode 13 . electrodes 11 and 13 are referred to herein as “ status ” electrodes , as they assist in determining the initial status of the various nerve pathways ). the epidural electrode is placed in the epidural space of the spine . alternatively , the depolarization of a portion of the patient &# 39 ; s cauda equina may be achieved by conducting a stimulus pulse having a known current level between a pair of status ( baseline ) electrodes 12 and 14 , which may be positioned adjacent the ( thoracic / lumbar ) t / l junction ( above vertebra l1 ), as shown . status electrodes 12 and 14 may be positioned in - line at the t / l junction , ( as shown in fig1 ). status electrodes 12 and 14 could also be positioned on opposite lateral sides of the t / l junction . in a preferred aspect , neuro - muscular ( i . e ., emg ), responses to the stimulus pulse by muscles coupled to nerves near the stimulating electrode are detected by electrodes positioned at each of a plurality of myotome locations mr1 , mr2 , and mr3 on the patient &# 39 ; s right leg , and myotome locations ml1 , ml2 , and ml3 on the patient &# 39 ; s left leg . the sensing of neuro - muscular responses at these locations may be performed with needle electrodes , or electrodes placed on the surface of the patient &# 39 ; s skin , as desired . an emg response at each location mr1 to mr6 is detected when the maximum peak - to - peak height of the emg response to the stimulus pulse is greater than a predetermined mv value ( called “ onset ”). accordingly , the current level required to elicit an onset emg response is called the “ onset ” current level . as described below , the current level of the stimulus pulse or signal applied to the electrode 11 or electrodes 12 , 14 may be incremented from a low level until an onset emg response is detected for one or more of the myotome locations mr1 to ml3 . it is to be understood that myotome sensing may be carried out at more than the three distal locations illustrated on each of the patient &# 39 ; s legs in fig1 . generally , as greater numbers of distal myotome locations are monitored , a greater number of spinal nerves corresponding to each of these myotome locations can be individually monitored , thereby enhancing the present system &# 39 ; s nerve detection ability over a larger section of the patient &# 39 ; s spinal column . it is also to be understood that the present invention can be easily adapted to cervical or thoracic spinal applications ( in addition to the illustrated lumbar application of fig1 ). in this case an appropriate portion of the spinal column is depolarized and myotome - sensing locations are selected according to the physiology of the associated nerves for portion of the spinal column of interest . in exemplary aspects , therefore , preferred myotome - sensing locations may therefore include locations on the patient &# 39 ; s arms , anal sphincter , bladder , and other areas , depending upon the vertebrae level where the spinal surgery is to be performed . in a preferred aspect , the current level of the stimulus signal conducted between status electrodes 11 and 13 ( or 12 and 14 ) is incrementally increased in a staircase fashion as shown in the current staircase of fig2 from a low value until an onset emg response is detected at one or more myotome locations . in a preferred embodiment , onset emg response peak - to - peak value is between 60 mv and 80 mv . ( it is noted , however , that depending on the location the stimulating electrode relative to the nerve corresponding to a myotome and the nerve health / status , an onset emg response may not be detected as the current level is incremented from the lowest level to the highest level shown in fig2 .) in the illustrated exemplary aspect , the current level is shown as increasing from 4 ma to 32 ma , in eight 4 ma increments where the current level is incremented until an onset emg response is detected . the present invention is not limited to these values and other current ranges ( and other numbers “ steps ” in the staircase ) may also be used , as is desired . at lower current levels , an onset neuro - muscular ( i . e ., emg ) responses to the stimulus pulse may not be detected at each myotome ml1 to mr3 location . however , as the current level of the stimulus signal is incrementally increased ( i . e . : moving up the staircase , step - by - step ), an onset neuro - muscular ( i . e ., emg ) response may eventually be detected at each of the various myotome locations ml1 through mr3 for each of the six associated spinal nerves . as noted whether an onset emg response is detected for myotome depends on the location of the electrode relative to the corresponding nerve and the nerve status / health . for example , when a nerve is compressed or impaired , the current level required to generate an onset emg response may be greater than the similar , non - compressed nerve at a similar distance from the stimulating electrode . accordingly , the onset neuro - muscular response for each of the various myotome ml1 to mr3 locations may be elicited at different stimulus current levels due at least in part to the various individual spinal nerves being compressed , impaired , etc ., and also due simply to differences in the individual nerve pathway sensitivities . for example , referring to the example illustrated in fig1 , a stimulus signal having an initial current level is conducted between electrodes 11 and 13 ( or between electrodes 12 and 14 ). the current level of the stimulus pulse is increased step - by - step according to the intensity staircase shown in fig2 until an onset emg response is detected at one or more selected myotomes . in particular , a response to the increasing current level stimulus pulse is detected at each of the various myotome locations ml1 through mr3 . because each of the spinal nerve paths corresponding to the various myotome locations ml1 through mr3 may have different sensitivities ( as noted ), different onset emg responses may be detected at the different onset current levels for different myotome locations . for example , table 1 illustrates the current level required to elicit an onset emg response for myotome location . as seen in table 1 , myotome location ml1 detected an onset emg response to the stimulus pulse for a current level of 4 ma . similarly , myotome mr2 detected an onset neuro - muscular / emg response to the stimulus pulse for a current level of 24 ma , etc . summarizing in tabular form : the above detected stimulus current levels may then be optionally scaled to correspond to stimulus staircase levels 1 through 8 , with the maximum signal strength of 32 ma corresponding to “ 8 ”, as follows , and as illustrated for each of myotome locations ml1 to mr3 , as shown in table 2 based on the levels shown in table 1 . accordingly , by depolarizing a portion of the patient &# 39 ; s cauda equina and by then measuring the current amplitude at which an onset neuro - muscular ( i . e ., emg ) response to the depolarization of the cauda equina is detected in each of a plurality of spinal nerves , ( i . e . : at each of the myotome locations corresponding to each of the individual spinal nerves ), a method for determining the relative neuro - muscular response for each of the plurality of spinal nerves is provided . as such , the relative sensitivities of the various spinal nerve pathways with respect to one another can initially be determined . this information may represent the relative health or status of the nerves coupled to each myotome location where the stimulating electrode is approximately the same distance from each of the corresponding nerves . for example , the nerve corresponding to myotome location mr2 required 24 ma to elicit an onset emg response in the corresponding muscle . accordingly , this nerve may be compressed or otherwise physiologically inhibited . these respective stimulus pulse current levels at which an onset neuro - muscular response is detected for each of myotome locations ml1 through mr3 are detected may then be electronically stored ( as an initial “ baseline ” set of onset emg response current levels ). in a preferred aspect , these stored levels may then be used to perform nerve detection for a probe at a location other than the midline as will be explained . as noted , once an onset neuro - muscular or emg - response has been detected for each of the myotome locations , it is not necessary to apply further increased current level signals . as such , it may not be necessary for the current level of the signal to reach the top of the current level staircase ( as shown in fig2 ) ( provided a response has been detected at each of the myotome locations ). by either reaching the end of the increasing current amplitude staircase , ( or by simply proceeding as far up the staircase as is necessary to detect a response at each myotome location ), the present system obtains and stores an initial “ baseline ” set of current level onset values for each myotome location . these onset values may be stored either as absolute ( i . e . : ma ) or scaled ( i . e . : 1 to 8 ) values . as noted these values represent the baseline or initial nerve status for each nerve corresponding to one of the myotome locations . this baseline onset current level may be displayed as a fixed value on a bar graft of leds such as shown in fig8 a or 8 b . at a later point , the nerve status of the nerves corresponding to the myotomes may be determined again by applying a varying current level signal to the midline electrodes . if a procedure is being performed on the patient , the onset current level for one or more of the corresponding nerves may change . when the onset current level increases for a nerve this may indicate that a nerve has been impacted by the procedure . the increased onset current level may also be displayed on the bar graft for the respective myotome ( fig8 a / 8 b ). in one embodiment , the baseline onset current level is shown as a particular color led in the bar graph for each myotome location and the increased onset current level value is shown as a different color led on the bar graph . when the onset current level decreases for a nerve this may indicate that a nerve has been aided by the procedure . the decreased onset current level may also be displayed on the bar graft for the respective myotome . in a preferred embodiment , the decreased onset current level value is shown as a third color led on the bar graph . when the onset current level remains constant , only the first color for the baseline onset current level is shown on the bar graph . in one embodiment , a blue led is depicted for the baseline onset current level , an orange led is depicted for an increased ( over the baseline ) onset current level , and a green led is depicted for a decreased onset current level . in one embodiment when the maximum current level in the staircase does not elicit an onset emg response for a myotome , the baseline led may be set to flash to indicate this condition . accordingly , a clinician may periodically request nerve status ( midline stimulation ) readings to determine what impact , positive , negative , or neutral , a procedure has had on a patient . the clinician can make this assessment by viewing the bar graphs on the display shown in fig8 for each of the myotome locations . the above determined initial set baseline neuro - muscular response onset current levels for each nerve pathway ( myotome location ) may then be used in the first ( i . e . : nerve sensing ) aspect of the present invention , in which a system is provided for detecting the presence of a spinal nerve adjacent to the distal end of a single probe 20 , or either of probes 20 or 22 . ( it is to be understood , however , that the forgoing nerve status system ( which may experimentally determine neuro - muscular response onset values ) is an optional aspect of the present nerve detection system . as such , it is not necessary to determine such relative or absolute neuro - muscular response baseline onset current levels as set forth above prior to nerve detection . rather , generally expected or previously known current onset levels may instead be used instead . such generally expected or previously known current onset levels may have been determined by experiments performed previously on other patients . in accordance with the first aspect of the present invention , nerve detection ( performed as the surgical tool or probe is advancing toward the operative site ), or nerve surveillance ( performed in an ongoing fashion when the surgical tool or probe is stationary has already reached the operative site ) may be carried out , as follows . the first ( nerve detection / surveillance ) aspect of the invention will now be set forth . returning to fig1 , a system is provided to determine whether a nerve is positioned closely adjacent to either of two probes 20 and 22 . in accordance with the present invention , probes 20 and 22 can be any manner of surgical tool , including ( electrified ) cannulae through which other surgical tools are introduced into the patient . in one aspect of the invention only one probe ( e . g . : probe 20 ) is used . in another aspect , as illustrated , two probes ( e . g . : 20 and 22 ) are used . keeping within the scope of the present invention , more than two probes may also be used . in one preferred aspect , probe 20 is an electrified cannula and probe 22 is a “ confirmation electrode ” which can be inserted through cannula / probe 20 , as will be explained . probes 20 and 22 may have electrified distal ends , with electrodes 21 and 23 positioned thereon , respectively . ( in the case of probe 20 being a cannula , electrode 21 may be positioned on an electrified distal end of the cannula , or alternatively , the entire surface of the electrified cannula may function as the electrode ). nerve detection is accomplished as follows . a stimulus pulse is passed between electrode 21 ( disposed on the distal end of a probe 20 ) and patient return electrode 30 . in instances where a second probe ( 22 ) is also used , a stimulus pulse is passed between electrode 23 ( disposed on the distal end of a probe 22 ) and patient return electrode 30 . in one aspect , electrodes 21 or 23 operate as cathodes and patient return electrode 30 is an anode . in this case , probes 20 and 22 are monopolar . preferably , when simultaneously using two probes ( 20 and 22 ) the stimulus pulse emitted by each of electrodes 21 and 23 is multiplexed , so as to distinguish between their signals . it should be understood that electrodes 21 and 23 could be replaced by any combination of multiple electrodes , operating either in monopolar or bipolar mode . in the case where a single probe has multiple electrodes ( replacing a single electrode such as electrode 21 ) probe 20 could instead be bi - polar with patient return electrode 30 no longer being required . subsequent to the emission of a stimulus pulse from either of electrodes 21 or 23 , each of myotome locations ml1 through mr3 are monitored to determine if they exhibit an emg response . in a preferred aspect , as shown in fig3 , the intensity of the stimulus pulse passing between electrodes 21 and 30 or between 22 and 30 is preferably varied over time . most preferably , the current intensity level of the stimulus pulse is incrementally increased step - by - step in a “ staircase ” fashion . as can be seen , the current may be increased in ten 0 . 5 ma steps from 0 . 5 ma to 5 . 0 ma . this stimulus pulse is preferably increased one step at a time until a neuro - muscular ( i . e ., emg ) response to the stimulus pulse is detected in each of myotome locations ml1 through mr3 . for myotome locations that exhibit an emg response as a result of the stimulus pulse , the present invention then records the lowest amplitude of current required to elicit such a response . subsequently , this stimulus level is interpreted so as to produce an appropriate warning indication to the user that the surgical tool / probe is in close proximity to the nerve . for example , in a simplified preferred aspect , the staircase of stimulus pulses may comprise only three levels , ( rather than the 8 levels which are illustrated in fig3 ). if an emg response is recorded at a particular myotome location for only the highest level of stimulation ( i . e . : the third step on a 3 - step staircase ), then the system could indicate a “ low ” alarm condition ( since it took a relatively high level of stimulation to produce an emg response , it is therefore unlikely that the tool / probe distal tip ( s ) are in close proximity to a nerve ). if an emg response is instead first recorded when the middle level of stimulation ( i . e . : the second step on the 3 - step staircase ) is reached , then the system could indicate a “ medium ” alarm condition . similarly , if an emg response is recorded when the lowest level of stimulation ( i . e . : the first step on the 3 - step staircase ) is reached , then it is likely that the probe tips ( s ) are positioned very close to a nerve , and the system , could indicate a “ high ” alarm condition . as can be appreciated , an important advantage of increasing the stimulus current intensity in a “ staircase ” function , increasing from lower to higher levels of current intensity is that a “ high ” alarm condition would be reached prior to a “ low ” alarm condition being reached , providing an early warning to the surgeon . moreover , as soon as a “ high ” alarm condition is reached , the present invention need not continue through to the end ( third step ) of the staircase function . in preferred aspects , when the current level of the applied signal to the probe ( 20 or 22 ) elicits an emg response greater than the pre - determined onset emg response , the current level is not increased . in the above - described simplified ( only three levels of stimulation ) illustration of the invention , it was assumed that all nerves respond similarly to similar levels of stimulation , and the proximity ( nerve detection ) warning was based upon this assumption . specifically , in the above - described simplified ( three levels of stimulation ) illustration , there was an assumed one - to - one ( i . e . linear ) mapping of the emg onset value data onto the response data when determining what level of proximity warning indication should be elicited , if any . however , in the case of actual spinal nerve roots , there is not only a natural variability in response onset value threshold , but there is often a substantial variation in neuro - muscular response onset values between the nerve pathways caused as a result of certain disease states , such as nerve root compression resulting from a herniated intervertebral disc . accordingly , in a preferred aspect of the present invention , the initial “ baseline ” neuro - muscular emg response onset value data set which characterizes the relative emg onset values of the various nerve roots of interest , ( as described above ), is used to guide the interpretation of emg response data and any subsequent proximity warning indication , as follows . referring back to fig1 and table 1 , the stimulation staircase transmitted between electrodes 11 and 13 ( or 12 and 14 ) resulted in measures neuro - muscular ( i . e . : emg ) response onset values of 4 , 16 , 20 , 16 , 24 and 12 ma at myotome locations ml1 , ml2 , ml3 , mr1 , mr2 and mr3 , respectively . as can be seen , twice the intensity of current was required to produce a neuro - muscular response at mr2 as was required to produce a neuro - muscular response at mr3 ( since “ 24 ” ma is twice as big as “ 12 ” ma ). thus , the nerve pathway to mr3 is more “ sensitive ” than to mr2 ( since mr3 is able to exhibit a neuro - muscular response at ½ of the current intensity required to exhibit a neuro - muscular response at mr2 ). consequently , during nerve detection , when electrode 21 or 23 ( positioned on the distal end of tool / probe 20 or 22 ) is positioned adjacent the nerve root affiliated with mr3 , twice the current stimulation intensity was required to produce an emg response . in contrast , when electrode 21 or 23 ( on the distal end of tool / probe 20 or 22 ) was positioned adjacent to the nerve root affiliated with mr2 , the same level of stimulation that produced a response at mr3 would not produce a response at mr2 . in accordance with preferred aspects of the present invention , the sensitivities of the various spinal nerve pathways ( to their associated myotomes ) are incorporated into the nerve detection function of the invention by incorporating the various neuro - muscular response onset values , as follows . a decision is made that either of electrodes 21 or 23 are positioned adjacent to a spinal nerve when a neuro - muscular response is detected at a particular myotome location at a current intensity level that is less than , ( or optionally equal to ), the previously measured or input emg response onset value for the particular spinal nerve corresponding to that myotome . for example , referring to myotome location ml1 , the previously determined neuro - muscular response onset level was 4 ma , as shown in table 1 . should a neuro - muscular response to the stimulus pulse be detected at a current intensity level at or below 4 ma , this would signal the operator that the respective probe electrode 21 ( or 23 ) emitting the stimulus pulse is in close proximity to the spinal nerve . similarly , the neuro - muscular response onset value for myotome location ml2 was determined to be 16 ma , as shown in table 1 . accordingly , should a neuro - muscular response be detected at a current intensity level of less than or equal to 16 ma , this would indicate that respective probe electrode 21 ( or 23 ) emitting the stimulus pulse is in close proximity to the spinal nerve . in addition , as illustrated in fig4 , “ high ”, “ medium ” and “ low ” warning levels may preferably be mapped onto each stimulation staircase level for each myotome location . for example , the neuro - muscular onset level for ml1 was 4 ma , corresponding to the first level of the 8 - level status electrode current staircase of fig2 . thus , the first ( 4 ma ) step on the staircase is assigned a “ high ” warning level . level two ( 8 ma ) is assigned a “ medium ” warning level and level three ( 12 ma ) is assigned a “ low ” warning level . thus , if an emg response is recorded at ml1 at the first stimulation level , ( 4 ma ), a “ high ” proximity warning is given . if a response is detected at the second level ( 8 ma ), then a “ medium ” proximity warning is given . if a response is detected at the third level ( 12 ma ), then a “ low ” proximity warning is given . if responses are detected only above the third level , or if no responses are detected , than no warning indication is given . similarly , for ml2 , with a onset value of 16 ma , ( i . e . : the fourth level in the status electrode current staircase sequence ), the “ high ”, “ medium ” and “ low ” warning levels are assigned starting at the fourth step on the status electrode current staircase , with the fourth step being “ high ”, the fifth level being “ medium ” and the sixth level being “ low ”, respectively , as shown . accordingly , if an emg response is detected for ml2 at ( or above ) the first , second , third , or fourth surveillance levels , ( i . e . : 4 , 18 , 12 or 16 ma ), then a “ high ” warning indication will be given . for a response initially detected at the fifth level ( i . e . : 20 ma ), then a “ medium ” warning indication is given . if a response is not detected until the sixth level ( i . e . : 24 ma ), then a “ low ” warning indication is given . if responses are detected only above the sixth level , or not at all , then no indication is given . preferably , each of myotome locations ml1 through mr3 are monitored at conditions indicating “ high ”, “ medium ” and “ low ” likelihood of a nerve being disposed adjacent the surgical tool / probe . as can be seen in fig4 , ten levels are shown for each of the myotome locations , whereas the illustrated status electrode current staircase has only eight levels . these optional levels “ 9 ” and “ 10 ” are useful as follows . should scaled level 8 be the minimum onset level at which a neuro - muscular response is detected , levels “ 9 ” and “ 10 ” can be used to indicate “ medium ” and “ low ” warning levels , respectively . as explained above , the various neuro - muscular response current onset levels used in detection of spinal nerves may either have been either determined in accordance with the second aspect of the present invention , or may simply correspond to a set of known or expected values input by the user , or pre - set into the system &# 39 ; s hardware / software . in either case , an advantage of the present system is that different neuro - muscular response onset value levels may be used when simultaneously sensing for different nerves . an advantage of this is that the present invention is able to compensate for different sensitivities among the various spinal nerves . as can be seen comparing the current intensities of stimulus electrodes 11 and 13 ( or 12 and 14 ) as shown in fig2 ( i . e . : up to 32 ma ) to the current intensities of probe electrodes 21 and 23 as shown in fig3 ( i . e . : up to 5 . 0 ma ), the current intensities emitted by probe electrodes 21 and 23 are less than that of electrodes 12 and 14 . this feature of the present invention is very advantageous in that electrodes 21 and 23 are positioned much closer to the spinal nerves . as such , electrodes 21 and 23 do not depolarize a large portion of the cauda equina , as do electrodes 12 and 14 . in addition , the placement of electrode 11 in the epidural space ensures that the electrode is at a relatively known distance from the spinal nerves . in an optional preferred aspect of the invention , if a neuro - muscular response ( greater than the onset emg response ) is detected for all six myotome sensing locations ml1 through mr3 before all of the steps on the staircase is completed , the remaining steps need not be executed . moreover , if it has been determined that a maximal level of stimulation is required to elicit an emg response at a particular myotome sensing location , then only the top three stimulation levels need to be monitored during the neuro - muscular response detection sequence . in this case , the top three monitored levels will correspond to “ high ”, “ medium ”, and “ low ” probabilities of the surgical tool / probe being disposed adjacent the a nerve . in another optional aspect , if any of the myotome locations do not respond to the maximum stimulation level ( i . e . : top step on the staircase ), they are assigned the maximum scale value ( i . e . : a “ low ” warning indication ). preferably , each of the spinal nerves monitored at myotome locations ml1 through mr3 will correspond to nerves exiting from successive vertebrae along the spine . for example , as shown in fig5 , a main spinal nerve 50 will continuously branch out downwardly along the spinal column with spinal nerve 51 exiting between vertebrae l2 and l3 while nerve 52 passes downwardly . spinal nerve 53 exits between vertebrae l3 and l4 while spinal nerve 54 passes downwardly to l4 . lastly , spinal nerve 55 will exit between vertebrae l4 and l5 while spinal nerve 56 passes downwardly . as can be seen , neuro - muscular ( i . e ., emg ) response measurements taken at myotome location mr1 will correspond to emg signals in spinal nerve 51 , response measurements taken at myotome location mr2 correspond to emg signals in spinal nerve 53 , and response measurements taken at myotome location mr3 correspond to emg signals in spinal nerve 55 . in accordance with the present invention , the detection of a neuro - muscular ( emg ) response , whether in accordance with the first ( i . e . : nerve detection ), or second ( i . e . : establishing initial “ baseline ” neuro - muscular response onset values ) aspect of the invention , may be accomplished as follows . referring to fig6 , an illustration of the waveform characteristics of a stimulus pulse and a corresponding neuro - muscular ( emg ) response as detected at a myotome location is shown . an “ emg sampling window ” 200 may be defined at a fixed internal of time after the stimulus pulse 202 is emitted . the boundaries of window 200 may be determined by the earliest and latest times that an emg response may occur relative to stimulus pulse 202 . in the case of stimulation near the lumbar spine , these times are , for example , about 10 milliseconds and 50 milliseconds , respectively . during emg sampling window 101 , the emg signal may optionally be amplified and filtered in accordance with guidelines known to those skilled in the art . the signal may then be rectified and passed through a threshold detector to produce a train of pulses representing the number of “ humps ” of certain amplitudes contained in the emg waveform . a re - settable counting circuit may then count the number of humps and a comparator may determine whether the number of pulses is within an acceptable range . by way of example only , the number of acceptable pulses for emg responses elicited by stimulation in the lumbar spine region may range from about two to about five . if only one pulse is counted , then it is unlikely that a true emg response has occurred , since true emg waveforms are typically biphasic ( having at least one positive curved pulse response and one negative curved pulse response ) resulting in at least two pulses . this pulse - counting scheme helps to discriminate between true emg waveforms and noise , since noise signals are typically either sporadic and monophasic ( and therefore produce only one pulse ) or repetitive ( producing a high number of pulses during the emg sampling window ). in a further optional refinement , a separate noise - sampling window may be established to remove noise present in the emg responses to increase the ability of the system to discriminate between true emg responses and false responses caused by noise . the boundaries of noise sampling window are chosen such that there is no significant change of a true emg signal occurring during the window . for example , it may be deemed acceptable that one curved pulse of an emg response may be comprised primarily of noise , but if more than one curved pulse of an emg response is primarily comprised of noise , an alarm would be triggered indicating that excess noise is present on that particular channel . in preferred aspects of the present invention , both the optional second aspect of determining the neuro - muscular response onset values for each of the plurality of spinal nerves and the first aspect of sensing to detect if a nerve is positioned adjacent to a surgical tool / probe are repeated over time . preferably , the sensing of whether a nerve is positioned adjacent to a surgical tool / probe is continuously repeated in very short intervals of time , such that the operator can be warned in real time as the surgical tool / probe is advanced toward the nerve . the present system of determining the neuro - muscular response onset values for each of the plurality of spinal nerves is also preferably repeated , and may be repeated automatically , or under operator control . typically , the above two aspects of the present invention will not be carried out simultaneously . rather , when the neuro - muscular response onset values are being determined ( using electrodes 11 and 13 or 12 and 14 ), the operation of probe electrodes 21 and 23 will be suspended . conversely , when sensing to determine whether a nerve is positioned adjacent either of probes 20 or 22 , the operation of stimulation electrodes 11 and 13 or 12 and 14 will be suspended . a standard reference electrode 32 may be used for grounding the recording electrodes at the myotomes . fig6 depicts a particular exemplary embodiment of the present invention . other embodiments are also possible , and are encompassed by the present invention . pulse generator 100 creates pulse trains of an appropriate frequency and duration when instructed to do so by controller 118 . by way of example , the pulse frequency may be between 1 pulse - per - second and 10 pulses - per - second , and the pulse duration may be between 20 μsec and 300 μsec . pulse generator 100 may be implemented using an integrated circuit ( ic ), such as an icl75556 ( intensity ) or generated by a software module . amplitude modulator 102 produces a pulse of appropriate amplitude as instructed by controller 118 , and may comprise a digital - to - analog converter such as a dac08 ( national semiconductor ). the output of amplitude modulator 102 drives output stage 103 , which puts out a pulse of the desired amplitude . output stage 103 may comprise a transformer coupled , constant - current output circuit . the output of output stage 103 is directed through output multiplexer 106 by controller 118 to the appropriate electrodes , either to status ( baseline ) electrodes 11 and 13 , or to a combination of screw test probe 109 , probe electrode 21 , 23 and patient return electrode 13 . impedance monitor 104 senses the voltage and current characteristics of the output pulses and controller 118 elicits an error indication on error display 127 if the impedance falls above or below certain pre - set limits . input keys 116 may be present on a front panel of a control unit of the present invention , as depicted in fig8 , to allow the user to shift between modes of operation . emg inputs 128 to 138 comprise the six pairs of electrodes used to detect emg activity at six different myotome locations . it will be appreciated that the number of channels may vary depending upon the number of nerve roots and affiliated myotomes that need to be monitored . a reference electrode 140 may also be attached to the patient at a location roughly central to the groupings of emg electrodes 128 to 138 to serve as a ground reference for the emg input signals . electrodes 128 to 140 may either be of the needle - type or of the gelled foam type , or of any type appropriate for detecting low - level physiological signals . emg input stage 142 may contain input protection circuit comprising , for example , gas discharge elements ( to suppress high voltage transients ) and / or clamping diodes . such clamping diodes are preferably of the low - leakage types , such as sst - pads ( siliconix ). the signal is then passed through amplifier / filter 144 , which may amplify the signal differentially using an instrumentation amplifier such as an ad620 ( analog devices ). the overall gain may be on the order of about 10 , 000 : 1 to about 1 , 000 , 000 : 1 , and the low and high filter bands may be in the range of about 1 - 100 hz and 500 to 5 , 000 hz , respectively . such filtering may be accomplished digitally , in software , or with discrete components using techniques well known to those skilled in the art . the amplified and filtered signal then passes through rectifier 141 , which may be either a software rectifier or a hardware rectifier . the output of rectifier 146 goes to threshold detector 147 which may be implemented either in electronic hardware or in software . the output of threshold detector 147 then goes to counter 148 which may also be implemented by either software or hardware . controller 118 may be a microcomputer or microcontroller , or it may be a programmable gate array , or other hardware logic device . display elements 120 to 127 may be of any appropriate type , either individually implemented ( such as with multicolor leds ) or as an integrated display ( such as an lcd ).
methods for determining structural integrity of a bone within the spine of a patient , the bone having a first aspect and a second aspect , wherein the second aspect separated from the first aspect by a width and located adjacent to a spinal nerve . the methods involve applying an electrical stimulus to the first aspect of the bone ; electrically monitoring a muscle myotome associated with the spinal nerve to detect if an onset neuro - muscular response occurs in response to the application of the electrical stimulus to the first aspect of the bone ; automatically increasing the magnitude of the electrical stimulus to until the onset neuro - muscular response is detected ; and communicating to a user via at least one of visual and audible means information representing the magnitude of the electrical stimulus which caused the onset neuro - muscular response .