it is to be understood that the figures and the descriptions of the present invention have been simplified to illustrate elements that are relevant for a clear understanding of the present invention several standard optical elements and other components are used to expand and collimate and form the laser beam and to control and process it . those of ordinary skill in the arts will recognize that these and other optical elements and / or steps are well known in the art , but because they do not facilitate a better understanding of the present invention , a discussion of such elements and steps is not provided herein . the disclosure herein is directed to all such variations to such elements and methods known to those skilled in the art . fig1 is a block diagram of an embodiment of the ocular pulse analyzer . a solid state laser 101 produces a pulsed axially symmetric gaussian beam of 670 nm wavelength and 1 milliwatt power , which is injected along the incident - beam - line 10 into the beam forming optics module 102 , which forms a small diameter low divergence exit beam of up to 500 micrometers diameter and less than 1 . 0 milliradians divergence , which strikes the apex of the cornea o at a 65 to 75 degree angle with respect to the eye visual axis . the incident beam is reflected onto the reflected - beam - line or at an angle of − 65 to − 75 degrees where it strikes a ccd array 105 forming a pixelated image of the reflected beam spot . the motion of the beam spot pixelated image on ccd array 105 is proportional to the movement of the eye front surface 104 as it responds to the ocular pulse . the eye orbit cup 109 is a compliant cup that forms an air tight seal on the eye orbit so that the equilibrium pressure at the eye front surface can be varied which allows parametric studies of the eye . cup 109 also is the interface to the patient &# 39 ; s face . the optics target module 107 projects an infinity image of an eye fixation target on which the patient focuses his vision thus minimizing random eye movement . accessory optics port module 108 which allows access for the external calibration of the optics system . both the fixation module 107 and the accessory optics port module 108 are aligned to the apparatus centerline . the ocular pulse analyzer beam forming optics are contained in beam tube 103 , and the reflected beam components are contained in beam tube 106 . the fixation module 107 , the observation module 108 and the eye orbit cup 109 are attached to an instrument stand 110 . the laser pulser is synchronized to the heart pulse by delayed triggers derived from the blood pulse sensors bps . during each heart pulse up to 128 pixelated beam spot widths are digitized by the analog - to - digital - converter adc and processed to provide measurements of the eye surface movement . the computer / display module cpu / disp system processes these data providing the operator with the iop and other parameters . these data are stored in the patient data base db . the cpu / disp receives the pulse and timing data and sends control data to the dac which then controls the laser pulser and the cup control module cup cntrl . by using the real time control module rtcntrl the operator controls the measurement and data processing parameters . fig2 illustrates an embodiment of a compact left eye optic head 200 with mirror folded beam lines allowing high angle light reflection on the cornea . the incident laser beam from laser 101 is transformed by the beam forming module 102 which is comprised of a 2 . 5 × inverted kepler &# 39 ; s telescope that expands and collimates the beam . kepler &# 39 ; s telescope consists of a diffraction limited entrance lens 201 such as an infinity corrected 5 × microscope objective of 36 mm focal length and numerical aperture 0 . 1 , which forms a beam waist of about 14 micrometers diameter at image plane 201 a , followed by an exit lens 202 such as a 90 mm focal length doublet located about one focal length from plane 201 a which forms a well collimated exit beam of at most 10 mm diameter and a total beam divergence of less than 0 . 5 mrad at the entrance of beam shaper , collimator and dump module 203 which attenuates and collimates the beam using apertures of decreasing diameter . at the beam shaper , collimator and dump module 203 exit the beam has a diameter no larger than 500 micrometers , a divergence of less than 1 . 0 mrad and a power of less than 1 microwatt . the beam then strikes turning mirror 204 , which reflects the incident beam so that it strikes the cornea at an angle of from 65 to 75 degrees to the normal of the eye where it is reflected at an equal and opposite angle striking turning mirror 205 , which reflects the beam onto the normal to ccd array 105 . the beam then passes through the quadrature error detectors 206 which detect reflected beam centering and out of range reflected beam pulses , finally impinging onto ccd array 105 which forms a pixelated image of the reflected beam spot . to provide noise and stray light shielding ; the beam forming module 102 is mounted in beam tube 207 , the reflected beam tube components 206 and 105 in beam tube 208 and the compact optic head 200 in instrument case 209 , which also mounts the orbit cup 109 and mounts the fixation module 107 and the accessory optics port module 108 . as may be understood by those possessing an ordinary skill in the pertinent arts instrument case 209 may be mounted on a standard slit lamp bench or other ophthalmic examination stand . fig3 details an embodiment of a beam shaper , collimator and beam dump module 203 which simultaneously forms the probe beam that is required for observing the unperturbed movement of the eye front surface . the expanded laser beam enters module 203 through an aperture in wall 302 where the laser beam diameter is reduced by striking the walls which are conical and may be made of graphite , the beam then passes through four alternating radial light traps 306 and four decreasing apertures 304 further reducing the beam diameter , divergence and power . light traps 306 collect large angle light rays , and scattered rays from the wall by multiple reflections in the radial traps further reducing stray light . after passing through a beam defining exit aperture 308 the beam power may be reduced by a factor greater than 1000 , may have a reduction in beam divergence to less than 1 milliradian and a diameter of less than 500 micrometers . as may be understood by those possessing an ordinary skill in the pertinent arts the apertures may be produced by laser or other machining means and may be coated with an optically absorbent coating by sputtering or other means . the internal parts may be assembled with spacers into a stack that is self aligning . fig4 illustrates the eye fixation module 107 and accessory optics port module 108 . an incandescent light source 402 illuminates a ground glass 404 , which illuminates an optical fixation target 406 . light from target 406 passes through beam splitter 408 , onto lens 410 which forms an image of the fixation target at infinity , which the patient fixes his eye on , minimizing random eye motion . light from the eye surface 412 is reflected 90 degrees by beam splitter 408 onto lens 414 which forms an image of eye surface 412 on at the exit of the accessory optics port 416 , which provides access for external calibration of the optics system . fig5 shows a geometric model of how the reflective head functions . initially the optic head is aligned to the eye surface at t 0 the time of the systolic ocular pulse , when the eye surface 104 has moved to its maximum outward extent 104 p 1 . at this time the optics projects the apertured beam spot image onto the corneal apex ( 0 , 0 ) and reflects it onto the ccd array 105 which forms a pixelated spot image that is collected by the data processing system . as the ocular pulse amplitude reduces , the eye surface 104 moves inward . the projection of the incident beam is not changed , but the angle of incidence to the perturbed eye surface is changed . the reflected light centroid is shifted on the ccd array 105 , and the relative position of the beam on the detector increases . a similar situation occurs when the ocular pulse pressure is raised , except that the reflected light shift moves in the opposite direction . the curvature of the cornea and the change in the location of the eye surface normal with respect to the incident beam provide a 50 times magnification of the eye surface movement at an incident angle of 75 degrees with an equal incident and reflected beam drift length . the measurement of the eye surface motion can be explained from the single ray trace deflection diagram given in fig5 which shows two positions of the eye surface 104 during a single ocular pulse . at time t 0 the eye surface 104 is at ( 0 , 0 ) where the incident beam strikes the cornea . as the ocular pulse amplitude decreases the eye front surface 104 moves radially inward along the eye normal axis va , moving to the second eye surface 104 position 104 p 2 . to measure this movement we place a small diameter , low divergence light source at the point ( x0 , y0 ) aligned so that the center of the output beam intersects the initial eye surface 104 p 1 at ( 0 , 0 ). the angle a 0 between the input ray and the eye surface normal axis is the angle of incidence of the input beam . physically the laws of reflection apply and the incident light ray is reflected along line ( 0 , 0 )-(− x0 , y0 ) where it strikes the detector at the pixel located at the point (− x0 , y0 ) where the beam intensity profile is collected and the profile center of gravity calculated . at time ( t o + δt ) the eye surface 104 moves towards the eye center along the eye normal until it reaches the second eye surface position 104 p 2 where the incident beam intersects the surface at the point ( xn , yn ) and is reflected to the array detector at point ( xs , ys ) along a new normal and a different angle of incidence where another beam profile is collected and a center of gravity calculated . the distance between the two reflected beam detector profiles is proportional to the displacement of the two eye surface locations . fig6 through 8 show the dependence of magnification on the angle of incidence , the pixelated signal displacement as a function of the eye surface motion and the fraction of beam reflected power as a function of the angle of incidence . fig6 shows the dependence of the reflective head sensor magnification on the angle of incidence a 0 . there is a strong dependence of magnification on the angle of incidence . facial obstructions limit the maximum angle of incidence to 75 degrees or less with a useful range of 65 to 75 degrees corresponding to a magnification range of about 30 to 50 times . fig7 is a plot of the pixelated beam spot image displacement as a function of the eye surface movement for a 12 . 5 mm radius spheroidal eye ball with an 8 . 5 mm corneal radius and an incident beam angle of 75 degrees and a magnification of 50 ×. note that a 50 micrometer movement of the eye surface as it responds to the ocular pulse causes a 450 micrometer displacement on ccd array 105 . fig8 shows the dependence of the energy reflected from the eye as a function of the beam incident angle for both incoherent and coherent light beams . the model results show that a coherent beam reflects more beam energy than an incoherent beam . fig8 also shows that for an incident angle of 75 degrees that the reflectivity of the coherent beam is 32 % and that of the incoherent beam is 20 %. the coherent beam reflected power is 1 . 6 times as high as the incoherent beam . the refracted beam powers are 68 % and 80 %. since we wish to lower the beam refracted into the eye an incident angle of 75 degrees is desirable . fig9 is a plot of a fft algorithm power spectrum calculated using a simulated ocular pulse amplitude wave train . note that the plot shows four spectral power peaks the zero frequency power intensity plus three higher frequency components . the area under the zero frequency peak directly gives the mean energy in the eye ball that generates the iop . the higher frequency spectral components are natural oscillations of the eye generated as the ocular pulse ebbs and flows without external drive or instrumental effects . variations in these components may give data on the health of the eye and the cerebrovascular system . those of ordinary skill in the art will recognize that many modifications and variations of the present invention may be implemented without departing from the spirit or scope of the invention . thus , it is intended that the present invention cover the modification and variations of this invention provided they come within the scope of the appended claims and their equivalents .
an instrument has been designed to study the pulsatile motion of the eye by analysis of a beam of light reflected from the corneal surface . a laser light beam probe of small spot size and low divergence strikes the cornea apex and the reflected movement is recorded by a sensor . analysis of the beam movement reveals the energy in the eye pulse without the necessity of physically touching the eye . the value of the intraocular pressure is determined from the calculated power spectrum . the sensitivity , accuracy and efficiency of the light beam makes possible studying both eyes concurrently and comparison of the pulse parameters of onset , amplitude and duration reveals any delay in circulation to an eye .