the process of the present invention increases the amount of p - dioxanone monomer recovered from a crude reaction product containing p - dioxanone by inhibiting polymerization of p - dioxanone during distillation or other processing of the crude reaction product . the term &# 34 ; crude reaction product &# 34 ; is intended to embrace the mixture of materials produced during the production of p - dioxanone . thus , the crude reaction product will not only contain p - dioxanone , but may also contain unreacted starting materials and other compounds employed in forming p - dioxanone . the blocking agent employed herein is not limited to any one particular compound or class of compounds . any compound can be employed as long as it protects the active groups on residual reactants with groups that do not function as polymerization initiators . the blocking agent , in its original form as added to the crude reaction product or in whatever form the agent attains after reacting with the residual reactants , should not be reactive towards p - dioxanone . examples of such compounds include benzyl halide and dihalomethylbenzene , preferably benzyl bromide and dibromomethylbenzene . a mixture of benzyl bromide and pyridine in a weight ratio of 2 : 1 has been found to provide particularly good results . the amount of blocking agent utilized can vary widely , i . e ., from about 2 to about 25 weight percent based on the weight of the crude reaction product and its p - dioxanone content . the blocking agent can be added , either as a liquid or a solid , to the crude reaction product . where a solid blocking agent is employed it must either be soluble in the crude reaction product or added with an appropriate solvent . preferably the crude reaction - product is dried with sodium bicarbonate or any other suitable drying agent and filtered to remove any impurities before the blocking agent is added . the mixture of crude reaction product and blocking agent can be distilled under heat and reduced pressure to provide p - dioxanone in a greater yield than which would otherwise be obtained . as noted earlier , when p - dioxanone is formed from the dehydrogenation of deg , protecting the reactive hydrogens on deg with unreactive groups leads to a significant decrease in the extent to which p - dioxanone is polymerized prior to separation and distillation . furthermore , an additional benefit has been observed in that protected forms of deg possess higher boiling points relative to p - dioxanone than deg per se . thus , it has been found that protected deg is easier to separate from p - dioxanone during the distillation recovery process . by utilizing the blocking agents herein the inventors have succeeded in obtaining p - dioxanone in yields ranging from about 70 % to about 90 %. the dehydrogenation of deg is carried out in the presence of a metallic catalyst . such catalyst can be a pure metal , e . g ., copper , chromium , cobalt , iron , platinum , nickel , palladium , etc ., or a mixture containing two or more metals , e . g ., a copper - chromium mixture . a copper - chromium catalyst containing 27 . 4 percent copper and 44 . 9 percent chromium has been found to produce particularly good results and is preferred . the temperature at which the dehydrogenation of deg is carried out can vary widely , i . e ., from about 200 ° c . to about 240 ° c . preferably , the reaction is carried out at a temperature ranging from about 230 ° c . to about 235 ° c . polymers made from p - dioxanone have been employed in the manufacture of absorbable surgical devices . such surgical devices should be fabricated from polymers possessing a very high degree of purity , i . e ., purity of 99 % and higher , since the polymers themselves decompose and become absorbed within the body . thus , the distillate containing p - dioxanone can be further purified to obtain 99 %+ pure p - dioxanone monomer . methods of obtaining highly pure p - dioxanone from reaction products containing p - dioxanone include crystallization techniques , such as the processes disclosed in commonly owned copending u . s . application ser . no . 08 / 036 , 922 , the disclosure of which is incorporated by reference herein . the method disclosed therein includes the steps of forming a solution by dissolving crude p - dioxanone in an aliphatic ester , forming p - dioxanone crystals from the solution to provide a mixture and filtering the mixture to recover pure p - dioxanone . the steps can be repeated to obtain p - dioxanone of very high purity , e . g ., purity on the order of 99 % and higher . dioxanone obtained by the method of this invention can be polymerized by itself or in combination with other copolymerizable monomers , e . g ., glycolide , lactide , trimethylene carbonate , caprolactone , etc . the homopolymers and / or copolymers can be linear or branched and can be random , block or graft copolymers . the polymers and / or copolymers can be used in the fabrication of a wide variety of medical / surgical devices , e . g ., sutures , staples , clips , pins , prostheses , etc . processes for polymerizing p - dioxanone and forming surgical articles ( such as sutures ) therefrom are known to those skilled in the art . see , for example , u . s . pat . no . 4 , 052 , 988 the disclosure of which is incorporated herein by reference . diethylene glycol ( 2 kg ) is placed into a reaction chamber which contains a copper chromium catalyst 2 % of deg composed of 27 . 4 parts by weight copper and 44 . 9 parts by weight chromium . a temperature of between 220 ° c . and 240 ° c . is maintained throughout the reaction . the resulting crude reaction product containing p - dioxanone and unreacted deg is dried in molecular sieves ( 4 angstroms ) overnight and then filtered . the dried product is placed in a 3 - necked flask and benzyl bromide ( 100 g ) along with pyridine ( 50 g ) are added to the flask . the resulting mixture is distilled under reduced pressure at a distillation rate of about 60 drops per minute . in this way , 1 . 6 kg of p - dioxanone is recovered . obviously , other modifications and variations of the present invention are possible in light of the above teachings . it is therefore to be understood that changes may be made in particular embodiments of the invention described which are within the full intended scope of the invention as defined by the claims .
processes of producing 1 , 4 - dioxan - 2 - one are improved by the addition of a blocking agent to a crude reaction product containing p - dioxanone . the blocking agent reacts with unreacted starting materials in the crude reaction product to protect the active sites thereon with groups that do not initiate polymerization of p - dioxanone . the polymerization of p - dioxanone before its recovery from the process is thereby inhibited .