referring now to fig1 there is illustrated a clip 34 of the present invention . the clip 34 comprises a top leg member 62 , a connector portion 64 , and a second leg member 63 . the connector portion 64 comprises an elongated portion 77 and two spring members 65 , 66 . the first spring member 65 is located at the proximal end of the clip 34 and is coupled to the proximal end of the first leg member 62 . the second spring member 66 is located at the distal end of the clip 34 and is coupled to the distal end of the second leg member 63 . the first leg member 62 and the second leg member 63 are substantially parallel to each other along substantially their entire length . each leg member 62 , 63 has a tissue engaging surface 78 , 79 respectively . each tissue engaging surface interfaces with the tissue engaging surface of the other leg member . the tissue engaging surfaces 78 , 79 include scored surfaces 98 for holding tissue between the interfacing surfaces and preventing tissue from slipping out . the surfaces 78 , 79 may also have dimples 97 or the like to ensure closure and prevent movement of the clip 34 once it is placed on the tissue structure . the proximal ends of the leg members 62 , 63 form an opening 85 for capturing a tissue structure 99 ( fig5 ) such as a tubular vessel . the top leg member 62 includes two upper transverse tabs 75 located at the distal end of the top leg member 62 . the connector portion 64 includes two lower transverse tabs 76 located towards the distal end of the connector portion 64 . the clip has a height , h . the height is measured in a plane perpendicular to the ligating surfaces when the clip is passed through the shaft 5 , prior to placement over a tissue structure . the clips of the present invention are preferably made from various well - known materials or alloys of materials , for example , of titanium , tantalum , stainless steel , memory metals having super elastic characteristics or the various plastic materials that have some resiliency such as polyolefins , glycolide - lactide polymers and similar plastic materials . the yield strength of the material should sufficient to allow opening by the instrument of the clip , to place it over tissue and resiliently return to its original closed configuration . preferably , the material used is a titanium alloy , such as for example , titanium 3al - 2 . 5 v . fig1 illustrates a titanium strip 34a prior to performing the clip 34 from the strip 34a . transverse tabs 75 , 76 are formed in the titanium strip 34a by coining or other known manufacturing methods . the strip 34a is subsequently bent twice to form three substantially parallel portions , i . e ., the leg members 62 , 63 and connector portion 64 , and two bent portions , i . e ., the springs 65 , 66 . the bent portions act as springs biasing the respective ends of the attached leg member towards the opposite leg member , thus providing substantially uniform or substantially symmetrical biasing of the leg members towards each other . referring now to fig1 - 10 , there is illustrated a clip applier 1 of the present invention . a housing 4 includes a stationary handle 10 , a trigger 11 pivotally mounted to the housing 4 , and a knob 59 rotatably attached to the distal end of the housing 4 . the knob 59 and housing 4 are coupled to the proximal end of an elongated shaft 5 . the shaft 5 includes a stationary elongated lower jaw portion 41 terminating in jaw 9 , a grasper bar 31 , a feed bar 32 , a support tube 33 , a stack 35 of clips 34 , a feeder shoe 70 and , at its distal end 40 , a pair of jaws 8 , 9 for grasping and compressing a tissue structure 99 to be ligated . the outer diameter of the shaft 5 comprises the support tube 33 having a lumen through which extend the lower jaw portion 41 , grasper bar 31 , and feed bar 32 . the support tube 33 terminates just proximally of jaws 8 , 9 to permit pivotal action of jaws 8 , 9 the support tube 33 is constructed to resist excessive torquing to and / or deflection of the various parts of shaft 5 . the support tube 33 and the lower jaw portion 41 are rotatably attached to the housing 4 by way of rotating knob 59 . the knob 59 is attached to the support tube 33 by a press fit between the opening inner diameter of the knob 59 and the outer diameter of the proximal end of the support tube 33 . inwardly protruding lugs 48 of the knob 59 are rotatably engaged with outwardly protruding lugs 49 of the lower jaw portion 41 . the knob 59 permits 360 degree rotation of the shaft 5 with respect to the housing 4 . the trigger 11 includes a trigger arm 18 extending from the housing 4 so that the user may hold the handle 10 and actuate the trigger 11 by grasping the trigger arm 18 with the same hand . posts 12 molded into trigger 11 fit into bosses 13 molded into housing 4 , so as to permit pivotal movement of trigger 11 with respect to handle 10 . housing 4 further includes a feed cam 16 pivotally attached to the housing 4 and slidably coupled to the trigger 11 . the feed cam 16 is coupled on one end to a coupling mechanism 17 . the coupling mechanism 17 couples the force applied to the trigger 11 to the tissue grasping / compressing and clip advancing / placing functions of the device . the trigger 11 includes a trigger post 19 which moves within a slot 20 in the feed cam 16 . the trigger 11 is actuated by applying a force to the trigger arm 18 to rotate the trigger arm 18 towards the handle 10 . this force causes : the trigger 11 to pivot about posts 12 ; and the post 19 to move within the slot 20 to pivotally rotate the feed cam 16 with respect to the housing 4 . the rotation of the feed cam 16 multiplies the trigger force translating it into longitudinal movement of the coupling mechanism 17 as described in more detail below . the coupling mechanism 17 is arranged longitudinally with respect to the longitudinal axis of the shaft 5 . the coupling mechanism 17 is comprised of a grasper coupling 21 , a feeder coupling 22 , an in - line spring 23 and a return spring 24 . the proximal end of the feeder coupling 22 includes a rearward extending post 26 , and a radially extending circular surface 27 . the feed cam 16 has two radially extending arms 25 which straddle a proximal or rearward extending post 26 of the feeder coupling 22 , and are slidably mounted between radially extending circular surface 27 and rearward extending post 26 . the radially extending arms 25 translate the rotational movement of the feed cam 16 to longitudinal movement of the coupling mechanism 17 . longitudinal movement of the coupling mechanism 17 comprises two distinct steps . the first step comprises compression of the return spring 24 which has a lower spring preload and / or a lower spring constant than the in - line spring 23 , and therefore compresses with less force . the first step corresponds to the tissue grasping and compression step of the trigger actuation . the second step comprises the compression of the in line spring 23 , in general , for the most part , after the return spring 24 has compressed . the second step corresponds to the clip advancement and placement step of the trigger actuation . the distal end of the feeder coupling 22 is slidably fitted and longitudinally moveable within the proximal end of the grasper coupling 21 . the grasper coupling 21 includes a radially extending circular surface 28 . the in - line spring 23 is situated over the feeder coupling 22 and grasper coupling 21 , and between circular surface 27 and circular surface 28 . the in - line spring 23 acts on circular surface 27 and circular surface 28 to longitudinally bias feeder coupling 22 and grasper coupling 21 away from each other . the grasper coupling 21 includes a second radially extending circular surface 29 on its distal end . the proximal end of the return spring 24 abuts against the distal end of the second circular surface 29 . the lower jaw portion 41 includes a circular surface 36 on its proximal end enclosed within rotation knob 59 of housing 4 . the distal end of the return spring 24 abuts against the circular surface 36 . thus , the return spring 24 biases the grasper coupling 21 in a proximal direction away from the proximal end of the shaft 5 , i . e ., away from the circular surface 36 of the lower jaw portion . as an initial force is applied to the trigger arm 18 , the feed cam 16 advances the coupling mechanism 17 , the return spring 24 compresses , and the grasper coupling 21 longitudinally advances . upon application of an appropriate additional amount of force , the feeder coupling 22 will slide towards the grasper coupling 21 as the in line spring 23 compresses . tissue is grasped and compressed by the top jaw 8 closing towards the jaw 9 of the stationary lower jaw portion 41 . an elongated portion 37 of the lower jaw member 41 extends through an aperture 30 in the housing 4 and an aperture 96 in the knob 59 , and along the longitudinal axis of the shaft 5 . the elongated portion 37 is formed in a u - shape by side walls 38 and floor 39 . the elongated portion 37 ends in a lower jaw 9 . the grasper bar 31 is attached at its proximal end to the grasper coupling 21 and extends longitudinally through an opening 47 circular surface 36 and the elongated portion 37 of the lower jaw portion 41 . the grasper bar 31 includes a ceiling 69 and two side walls 68 . the two side walls 68 fit inside and adjacent side walls 38 of lower jaw portion 41 . the grasper bar side walls 68 have series of slots 67 which expose a series of notched surfaces 61 on the inside of the lower jaw portion side walls 38 forward longitudinal motion of the grasper coupling 21 is transferred to the grasper bar 31 . the top jaw 8 is located at the distal end of the grasper bar 31 . downwardly extending posts 55 on the distal end of the grasper bar 31 are inserted into corresponding slots 56 of top jaw 8 to movably attach the grasper bar 31 to the top jaw 8 . the top jaw 8 includes a pair of hooks 51 on each side of the proximal end of the jaw 8 . the hooks 51 pivotally engage the lower jaw 9 at indentations 52 in lower jaw 9 . the top jaw 8 and lower jaw 9 include interfacing tissue contacting surfaces 53 , 54 , respectively . jaw 8 includes a window 87 through which compressed tissue may be viewed during the tissue compressing stage , and where a clip may be viewed during the clip advancing stage . advancement of the grasper bar 31 pivots the top jaw 8 closed towards the lower jaw 9 so that the interfacing surfaces 53 , 54 move together to compress any tissue structure engaged between jaws 8 , 9 . when the top jaw 8 is closed towards the lower jaw 9 , the engaged tissue is forced into a tissue channel 57 in the lower jaw 9 . the tissue channel 57 helps to ensure that the tissue does not extrude distally out of the jaws 8 , 9 when the clip is advanced onto the tissue . the tissue channel 57 also assists in properly positioning the tissue for disengagement of the clip 34 from the instrument . a pair of upwardly extending tabs 58 at the distal end of the lower jaw 9 also assist in tissue placement between the jaws 8 , 9 by acting as a distal tissue stop . a pair of proximal tissue stops 100 incorporated into fronts of hooks 51 , prevent tissue from going into the device proximally of jaw 8 . the tissue channel 57 , tabs 58 and tissue stops 100 properly place the tissue in the amount to be ligated , where the clip disengages from the device . this is particularly important as the clip 34 in this embodiment does not extend as long as the jaws 8 , 9 . release of the trigger 11 releases the return spring 24 , which causes the grasper bar 31 to retract and the top jaw 8 to open . after the jaws 8 , 9 close over a tissue structure 99 to be ligated , the trigger arm 18 is squeezed further initiate the second step , i . e ., clip advancement and placement . as the trigger is squeezed , a step force arm 2 on the trigger 11 contacts a corresponding step force rib 6 on the housing 4 . when the return spring 24 is compressed and the jaws 8 , 9 closed to the force of the return spring 24 , a protrusion 3 on the step force arm 2 contacts the corresponding step force rib 6 which imparts an increase in the tactile force felt on the trigger arm 18 by the user . this increase in force denotes the separation between the jaw closing mode and the clip advancement mode in the two - stage , single stroke actuation . similarly , the feed cam 16 has an anti back - up arm 14 with a protrusion 15 at its distal end . anti back - up arm 14 contacts a corresponding backup rib 7 on the housing 4 to prohibit the reversal of the feed cam rotational motion . this occurs at the transition between the jaw closing mode and the clip advancement mode of the trigger stroke . the back - up rib 7 measures a complete stroke of the trigger before it permits the anti back - up arm 14 to disengage therefrom , thus ensuring the clip 34 is properly advanced all the way onto the tissue , as described in more detail below . two engagement arms 44 with inwardly protruding tabs 45 , extend from the proximal end of the feed bar 32 . the engagement arms 44 extend through an opening in the distal end of the grasper coupling 21 into the feeder coupling 22 . feeder coupling 22 has a center rib section 46 which is straddled by the engagement arms 44 of the feed bar 32 and is engageably coupled by tabs 45 . the feed bar 32 is advanced by the forward motion of the feeder coupling 22 . in the second mode , i . e ., the clip advancement and placement mode , trigger arm 18 advances the feeder coupler 22 which advances the feed bar 32 . the feed bar 32 extends through the opening 47 in circular surface 36 and longitudinally between the elongated portion 37 of the lower jaw portion 41 and the grasper bar 31 , ending in a slightly bent heel portion 43 . during the second trigger step , the heel portion 43 advances the distal most clip into the jaws 8 , 9 and over an engaged compressed tissue structure 99 . a stack 35 of clips 34 is preloaded into the clip applier in an end to end configuration along the longitudinal axis of the shaft 5 . the feed bar 32 also advances the stack 35 . the feed bar 32 sits on top of the floor 39 of the lower jaw portion 41 . the stack 35 of clips 34 sits on top of the feed bar 32 between the feed bar 32 and the ceiling 69 of the grasper bar 31 . the distal most clip 34 in the stack 35 is positioned beyond the heel 43 at the distal end of the feed bar 32 and just proximal of the lower jaw 9 . the stack 35 of clips 34 with a feeder shoe 70 positioned proximal of the last clip in the stack 35 , is advanced distally through the shaft 5 by the feed bar 32 . the feeder shoe 70 has a main body 71 and a cantilevered lower arm 72 biased away from the main body . a tab 73 extends downward from the lower arm 72 and engages in one of a longitudinal series of slots 60 in the feed bar 32 , i . e ., so that the feed shoe 70 is positioned just proximal of the last clip in the stack 35 . the feed shoe 70 further comprises transversely biased arms 74 extending from the sides of the feed shoe 70 . during the resting stage and when the grasper bar 31 is advanced , the arms 74 are in contact with the notched surfaces 61 of the lower jaw sides walls 38 . the notched surfaces 61 are then exposed by slots 67 in the grasper bar 31 side walls 68 . the arms 74 are biased outward to impede proximal movement of the feed shoe 70 . the arms 74 permit distal movement of the feed shoe 70 . the feed bar 32 is advanced , and the arms 74 of the feed shoe 70 pass over the walls 68 of the grasper bar 31 . the arms 74 then engage exposed notched surfaces 61 again , this time distally by one clip length . when the feed bar 32 is advanced , the feed shoe 70 is advanced because the tab 73 is engaged in one of the feed bar slots 60 . the distal end of the feed shoe 70 advances the stack 35 of clips 24 towards the distal end of the instrument . each time the trigger 11 advances the feed bar 31 , the feed shoe 70 advances by one clip length . the grasper bar 31 has a cantilevered lifter spring 86 located towards its distal end . the cantilevered lifter spring 86 extends down from the ceiling 69 of the grasper bar 31 . during the initial advancement of the grasper bar 31 , the distal most clip is moved from the longitudinal plane of the stack 35 into the longitudinal plane of the feed bar 32 . during the second step of the trigger stroke , distal end of the feed bar advances the distal clip 34 into the jaws 8 , 9 which have closed over , compressed and temporarily occluded a tissue structure 99 . after the first clip is placed , the next distal most clip is moved downward from the feed bar 32 by the cantilevered spring 86 , as the feed bar 32 is retracted at the end of the trigger stroke . the cantilevered spring 86 prevents the distal most clip from retracting with the feed bar 32 . thus , the distal most clip in the stack 35 is transferred by the cantilevered lifter spring 86 after the second stage of the trigger stroke is completed . a longitudinal channel 93 is formed in the lower jaw 9 through which a downwardly extending depression 88 of the feed bar 32 rides to ensure the proper placement of the distal end of the feed bar 32 with respect to the distal clip throughout clip advancement and placement . when the distal clip is lowered to the plane of the feed bar , the lower transverse tabs 76 ride on shelves 90 formed in the side walls 38 of the lower jaw 9 . the shelves 90 interface with the inner surface of the lower transverse tabs 76 . the upper transverse tabs 75 ride along ramps 91 which engage the inner surfaces of the upper tabs 75 and angle the upper tabs 75 towards the top jaw 8 , causing the inner tissue engaging surfaces 78 , 79 of the biased leg members 62 , 63 to separate from each other to provide the opening 85 . at the end of the ramps 91 the upper transverse tabs make a transition from the lower jaw 9 to rails 92 in the top jaw 8 . the rails 92 engage the inner surface of the upper transverse tabs 75 . thus , the first tissue engaging surface 78 of the first leg member 62 is advanced into the top jaw 8 above the compressed tissue structure 99 . the second tissue engaging surface 79 of the second leg member 63 is advanced into the lower jaw 9 below the compressed tissue structure 99 . throughout the advancement of the clip , the body of the clip is contained within longitudinal channels 93 and 94 in the top jaw 8 and lower jaw 9 , respectively . upper transverse tabs 75 advance to openings 95 towards the distal end of the top jaw 8 . the width of the opening 95 is greater that the inner width of the rails 92 and closely corresponds to the outside width of the upper transverse tabs 75 . the tabs 75 disengage from the top jaw 8 as they are advanced through the opening 95 , allowing the upper leg member 62 to resiliently move toward the lower leg member 63 and contact tissue structure 99 with the tissue engaging surface 78 . likewise , at approximately the same time , lower transverse tabs 76 reach opening 96 towards the distal end of the lower jaw 9 . the width of the opening 96 is greater that the inner width of the shelves 90 , and closely corresponds to the outside width of the lower transverse tabs 76 . this allows the tabs 76 to disengage from the lower jaw 9 through the opening 96 , allowing the lower leg member 63 to resiliently move toward the upper leg member 62 and contact tissue with the tissue engaging surface 79 . the position of the tabs 75 , 76 corresponds to the timing of leg member disengagement from the jaws 8 , 9 of the instrument , to correctly place the clip on the tissue . although an upper and lower set of transverse tabs are shown , a number of combinations , including a single tab alone , are possible for disengaging a clip from the instrument . in addition , the channel 94 in the lower jaw 9 curves upward at its distal end to urge the clip 34 upward as it is disengaged from the lower jaw 9 . also , a kickoff spring 101 having a free end 102 extends from distal end of floor 39 of lower jaw portion 41 through channel 94 of lower jaw 9 . free end 102 is biased upward towards top jaw 8 . the kickoff spring 101 is compressed downward as the clip 24 is advanced distally into jaws 8 , 9 . as top jaw 8 opens , the force holding the clip against the kickoff spring 101 is released and the spring 101 urges the clip out of the jaws 8 , 9 . the stack 35 of clips 34 is moved sequentially until all clips have been dispensed . the shaft 5 includes a clip indicator 80 which allows the user to identify when there are approximately two unused clips remaining in the instrument 1 . the clip indicator 80 comprises two longitudinally positioned holes 81 , 82 in the support tube 33 located towards the distal end of the support tube 33 and two corresponding holes 83 , 84 in the grasper bar 31 . the feeder shoe 70 has a colored marker 89 which shows through the holes 81 , 82 , 83 , 84 when the feeder shoe 70 passes underneath the holes 81 , 82 , 83 , 84 as it is advanced distally . when the feeder shoe 70 passes the first hole 81 and corresponding hole 83 , two clips remain and when the feeder shoe 70 passes under the second hole 82 and corresponding hole 84 , one clip remains . a track plug 50 is positioned within the opening 47 of the lower jaw 41 and within the proximal end of the grasper bar 31 , to reduce the outward flow of body cavity gases through the opening 47 . the plug 50 is held in place and motionless with respect to the longitudinal motion of the grasper bar 31 and feed bar 32 by return spring 24 . although the instrument is shown to have one moveable and one stationary jaw , the instrument may have both jaws moving to close over tissue to be occluded . fig3 a illustrates a preferred embodiment of the clip applier 1 prior to actuation . at this stage , as further illustrated in fig5 a , the jaws 8 , 9 are open and may be placed about a tissue structure 99 . fig4 illustrates an enlarged cross section of the shaft 5 corresponding to the initial position of the device as illustrated in fig3 a . the transverse arms 74 of the feeder shoe 70 extend through slots 67 in side walls 68 of grasper bar 31 and are engaged against the notched surfaces 61 of the lower jaw walls 68 . the tab 73 extends downward from the lower arm 72 and engages in one of a longitudinal series of slots 60 in the feed bar 32 . fig3 b illustrates the clip applier of fig3 a as it completes the tissue grasping stage of the trigger actuation . the protrusion 15 on the anti back - up arm 14 of the feed cam 16 has just engaged with the rib 7 of the housing . thus , until this point ( see fig3 a ) the user can release the trigger 11 to open and reposition jaws 8 , 9 . just prior to locking , the protrusion 15 reaches the rib 7 and an increased tactile force is perceived by the user in actuating the trigger arm 18 . the increased tactile force is a result of protrusions 3 on an arm 2 contacting rib 6 in housing 4 . this indicates to the user that any additional force applied to the trigger arm 18 will require the user to complete the clip placement in order to release the jaws 8 , 9 . fig4 b corresponds to the stage just prior to locking . the jaws 8 , 9 are closed and the distal most clip has not been significantly advanced . once the protrusion 15 engages with the rib 7 of the housing as shown in fig3 b , the trigger stroke must be completed . fig3 b illustrates the end of the first stage and the initiation of the second stage of the trigger actuation . the protrusion has engaged with the rib 7 and the clip placement stage has been initiated ( fig3 b ). fig4 b corresponds to the clip advancing stage of the trigger actuation also illustrated in fig3 b , 3c , 5c , 5d , and 5e . the feed bar 32 is advanced distally along with the feed shoe 70 which correspondingly advances the clip stack 35 the distance of one clip . transversely biased arms 74 move across walls 68 of grasper bar 31 . as shown in fig5 c , the distal clip sits distally of the feed bar 32 . the upper transverse tabs 75 of the first leg member 62 ride up ramps 91 to the top jaw 8 , separating the inner tissue engaging surfaces 78 , 79 of the biased leg members 62 , 63 from each other to provide the opening 85 . in fig5 d , the clip 34 is advanced over the tissue structure . in fig5 e , the clip is disengaged from the shelves 90 , rails 92 , jaws 8 , 9 at the distal end 40 . this corresponds to the end of the trigger stroke , as illustrated in fig3 c . when the clip 34 is disengaged and the trigger arm 18 is released , the trigger 11 will return to its original position illustrated in fig3 a . fig4 c illustrates the shaft of the instrument when the trigger is released after the end of the trigger stroke . the in line spring 23 causes the feed bar 32 to retract . the biased arms 74 of the feed shoe 70 , however , remain engaged against the walls 38 of the lower jaw portion 41 so that the feed shoe 70 remains stationary . the lower arm 72 of the feed shoe 70 ramps out of the slot 60a in feed bar 32 in which it was positioned and into the slot 60b distal of slot 60a . also , the next distal most clip is moved downward from the feed bar 32 as the feed bar 32 is retracted at the end of the trigger stroke . the cantilevered spring 86 prevents the clip from retracting into the feed bar 32 . thus , feed shoe 70 and feed bar 32 are positioned to advance the next clip upon a subsequent actuation of the trigger 11 . the clips may be loaded and stored in the shaft as illustrated or , alternatively , in the handle , or , both shaft and handle . the applier may be capable of applying a plurality of clips as shown or a single clip . also multiple clips may be simultaneously applied by adapting the device to accommodate multiple rows of clips and multiple disengagement means at the business end . a cutting means made be included in this embodiment , for cutting a ligated structure between two of the clips . referring now to fig1 - 16 there is illustrated an alternative embodiment of the present invention . an end effector 111 of a clip applying instrument is illustrated having : a shaft 105 ; a clip advancing fork 114 extending longitudinally through the lumen of a shaft 105 ; and a pair of pivotally attached hollow jaws 108 , 109 coupled to the distal end of the shaft 105 . the fork 114 has an upper prong 112 and a lower prong 113 , respectively . each prong 112 , 113 has a protrusion 116 , 117 extending transversely from the prongs 112 , 113 . each protrusion 116 , 117 has a camming surface 118 , 119 , respectively . the prongs 112 , 113 are respectively slidable within lumens 120 , 121 of jaws 108 , 109 . the lumens 120 , 121 of the jaws 108 , 109 include camming surfaces 128 , 129 corresponding to camming surfaces 118 , 119 of protrusions 116 , 117 . a partially formed deformable clip 122 is situated within the fork 114 . the clip 122 has legs 123 , 124 connected on their proximal end by a connecting member 125 and forming a narrow opening 126 on their distal end . the clip 122 is held by the legs 123 , 124 between the prongs 112 , 113 of the fork 114 . the jaws 108 , 109 are initially biased away from each other . as the clip fork 114 is advanced , the prongs 112 , 113 are advanced through the lumens 120 , 121 . as the fork 114 is advanced , the clip leg 123 slides within the lumen 120 of the top jaw 108 and the clip leg 124 slides within the lumen 121 of the bottom jaw 109 . in use , a tissue structure to be ligated is placed between the jaws 108 , 109 . the clip fork 114 is advanced , closing the jaws 108 , 109 together and pre - compressing the tissue structure between the jaws 108 , 109 . the fork 114 simultaneously advances the clip 122 over the pre - compressed tissue structure so that the tissue structure lies between the legs 123 , 124 of the clip 122 . the opening 126 of the semi - formed clip 122 is just sufficiently large enough to fit over a pre - compressed tissue structure and is small enough to fit within the shaft 105 . prior to any contact between camming surfaces 118 , 119 and camming surfaces 128 , 129 , the fork may be retracted , releasing the jaws 108 , 109 from the tissue structure before the clip 122 is closed over the tissue structure . as the clip fork 114 advances further , the camming surfaces 118 , 119 contact camming surfaces 128 , 129 which force the prongs 112 , 113 to close together . as the prongs close , they in turn force the legs 123 , 124 of the clip 122 to close together over the pre - compressed tissue . the clip 122 is made of a deformable material . thus when the clip 122 is closed , it is formed into its final shape and remains closed . the clip fork 114 may be retracted , thereby opening the jaws 108 , 109 , leaving the clip in place , ligating the tissue structure . ligating clips may be applied to blood vessels during a surgical procedure either as a single clip using a single clip applier or utilizing a multiple clip applier . the instrument may be inserted through a cannula during an endoscopic procedure and if a multiple clip applier is being used , the instrument may ligate or place clips on a number of vessels at a number of locations . the instrument may be made from various materials such as metals , plastic preferably a polycarbonate resin and the like . usually if the instrument is made from stainless steel the instrument will be reusable while if the instrument is made from plastic materials the instrument will be disposable . in certain embodiments of the instrument of the present invention , the instrument may be designed to accept a replaceable cartridge of clips . this may be accomplished with either a reusable instrument or semi - disposable instrument which is meant to be used a number of times on a single patient . having now described the present invention , it will be readily apparent to those skilled in the art that various modifications and alterations may be made to the present invention without departing from the spirit and scope thereof .
a clip , clip applier and method for ligating a tissue structure is provided . the applier has a two stage actuation . in the first stage , a tissue structure is positioned into the jaws of the clip applier the jaws close and lock to a preset force to compress and temporarily occlude the tissue structure . if satisfactorily positioned , the second stage is initiated in which a clip is advanced through the shaft of the clip applier in a closed position . at the distal end of the clip applier , the clip is opened slightly to capture the pre - compressed tissue structure , and is placed over the structure . the clip is then dissociated from the business end of the instrument . preferably the clip comprises two leg members disposed in close proximity to one another joined from opposing directions by a connecting element . the connecting element restricts separation of the leg members with opposing spring members so as to provide substantially uniform parallel deflection of the leg members from each other .