in one invention embodiment , a covered stent is formed using a spray process . by appropriately adjusting the spray process parameters , the polymer coating can be made to cobweb between the stent struts . this forms a structure akin to spunbonded , non - woven fabrics . fig1 shows a stent in which fibers of kynar have been caused to form between the stent struts . similarly , fig2 shows a stent in which fibers of solef have been caused to form between the struts . formation , in part , comes from rejecting standard process parameters , which are specifically chosen to minimize or avoid this cobwebbing effect . a particular configuration for a covered stent and a means to make this construct by a spray process is disclosed . this covered stent is made using the phenomena of cobwebbing with stent coverage . similar polymers can also be coated in a conformal way , without cobwebbing . adjusting the process conditions can vary the degree of cobwebbing . one can go from a stent with low coverage to one that is completely covered . at the level of the struts 30 , in fig6 , the coating 35 encapsulates the struts 30 . the polymer strands , filaments , or cobwebs 40 emanate from the sidewalls 45 , fig7 . fig3 illustrates a stent with high coverage of kynar flex 2800 . fig4 and fig5 show the highly covered kynar flex 2800 stent in close - up . process parameter control can yield very fine polymer - fiber structure . fig6 illustrates a conventional stent 10 formed from a plurality of struts 30 . the plurality of struts 30 are radially expandable and interconnected by connecting elements 14 that are disposed between adjacent struts 30 , leaving lateral openings or cutouts 20 between adjacent struts 30 . struts 30 and connecting elements 14 define a tubular stent body having an outer , tissue - contacting surface and an inner surface . although the embodiments of the present invention are described with reference to a stent , the application of the invention should not be limited to a stent and is equally applicable to other implantable medical devices . fig8 shows a stent 10 in cross - section ( axial ). cutouts 20 allow passage from the outside of the stent 10 to the inside . strut 30 is partially surrounded by cutouts 20 , which have sidewalls 45 . invention coating processes coat the stent 10 in two ways . the conformal coating portion 35 acts as a typical conformal coating . and the webbed coating portion 60 comprises filaments 40 that extend from the conformal coating portion 35 on a sidewall 45 to the conformal coating portion 35 of a separate part of the sidewall 45 or to another sidewall . in some embodiments , filaments 40 are substantially completely further inward than the surface 50 . in some embodiments , filaments 40 occupy 10 - 90 % of the areal space of cutouts 20 . in other embodiments , filaments 40 occupy 20 - 80 %, 30 - 70 %, or 40 - 60 % of the areal space of cutouts 20 . for purposes of this disclosure , areal space is defined as the area of the cutout 20 measured at the surface 50 . if filaments 40 occupy 50 % of the areal space of cutouts 20 , this means that filaments 40 block 50 % of the space occupied by the cutout . portions of some embodiments of polymer filaments are less than 1 micron in diameter with interfilament spacings of 1 - 5 microns . these filaments and spacings are similar to those seen in eptfe fabrics , which commonly compose stent covers . generally , polymer filaments average from 0 . 1 microns to 100 microns ; more narrowly , 0 . 2 microns to 80 microns or 0 . 5 microns to 20 microns . also , the interfilament spacing generally averages from 0 . 2 microns to 50 microns ; more narrowly , 0 . 5 microns to 25 microns or 0 . 5 microns to 10 microns . depending on the process parameters , the distribution of filament diameters can range from 0 . 1 microns to 100 microns , or 0 . 2 microns to 80 microns , or 0 . 5 microns to 20 microns . likewise , the distribution of interfilament spacing can range from 0 . 2 microns to 50 microns , or 0 . 5 microns to 25 microns , or 0 . 5 microns to 10 microns . both filament diameter and interfilament spacing are measured in the unexpanded , ready - for - delivery state for self - expanding stents . these values are measured in the ready - for - delivery state for balloon expandable stents . “ ready for delivery ” means that the medical device is completely manufactured , cleaned , packaged , etc . and could be implanted in a patient . in one embodiment , the stent is coated in a collapsed configuration with the struts nearly touching . on expansion , the polymer between the struts , in this embodiment , is subjected to very high strains . the following methods can be used to reduce this strain . the self - expanding stent can be coated in the expanded state . when collapsed , the mesh covering accordions or folds up . for balloon expandable stents , the stent can be expanded as much as possible and then coated . this will reduce the degree of strain the polymer must accommodate . current coating processes can create cobwebbing with a variety of polymers . for each material , those of ordinary skill in the art can determine the process parameters necessary for coating a medical device . examples of categories of such process parameters and useful trends are as follows : use solvents with higher volatility ( this is referred to as a volatility parameter ) use trailing solvents that are poor solvents for the polymer ( this is referred to as a solvation parameter ) increase the concentration of the polymer in the solvent ( this is referred to as a concentration parameter ) increase the spray nozzle temperature ( this is referred to as a spray nozzle parameter ) increase the dry nozzle temperature ( this is referred to as a dry nozzle parameter ) increase the flow rate ( this is referred to as a flow parameter ) increase the atomization pressure ( this is referred to as a atomization pressure parameter ) increase the surface tension of the solution ( this is referred to as a surface - tension parameter ) typically , when one spray nozzle is used , the stent is rotated and translated under the spray nozzle to coat all side evenly . in this configuration , one may increase the rotational speed of the stent relative to the spray nozzle . increasing the stent rotational speed can essentially wind coating solution strands and filaments around the stent . one of ordinary skill in the art recognizes the cumulative effect each of the above parameters has on the process . but for simplicity , each is discussed separately below . by modifying the parameters in one or more categories , a deposition process can be expected to transition from depositing a conformal polymer coating to a cobwebbed polymer coating . relative terms such as “ higher ” are referenced against the typical values for the same process parameters in conformal coating processes . this parameter relates to the volatility , or boiling point , of the polymer solvent . increasing the volatility of the solvent system is expected to increase the likelihood that a cobwebbed coating will form . “ solvent ” in this case refers to the overall solvent composition , which can be a mixture of individual solvents . rapid solvent evaporation during spraying leads to an increase in the viscosity of the droplets and coating on the stent . this increases the propensity for the solution to form strands that can interconnect struts . this parameter relates to the solubility of the polymer in the trailing solvent . as discussed above , a solvent composition dissolves the polymer for application . once the polymer solution has been deposited onto the device , solvent begins to evaporate . but the composition of the just - evaporated solvent vapor does not match the composition of the remaining liquid solvent . some solvent compositions will preferentially evaporate first . this means that , as the solvent evaporates , the composition of the remaining solvent smoothly changes from an initial composition to a final azeotropic composition . ( an azeotropic solvent composition naturally evaporates as a single component system ; i . e ., it has a fixed boiling point and evaporation does not shift the composition of the remaining liquid .) this final composition is typically rich in the solvent component or components that evaporate more slowly . this solvent component , the one that evaporates more slowly than the others , is called a trailing solvent . the solvation power of this trailing solvent may be characterized by the hildebrand solubility parameter . a solubility parameter may also be arrived at for the coating polymer . when the difference between these two solubility parameters increases , the solubility of the polymer in the solvent lessens . this trend is most applicable when the degree of hydrogen bonding of the solvent and polymer are similar . typically , this degree of hydrogen bonding is described as high , medium , or low . consequently , during spraying the more volatile solvent flashes off , and the polymer will tend to gel or precipitate in the trialing solvent . this gelation or precipitation prevents the formation of a smooth coating and can lead to cobwebbing . if the polymer is less soluble in the trailing solvent versus baseline conformal - process trailing solvent , the process with poorer polymer solubility will favor polymer cobwebs . this parameter relates to the overall polymer concentration in the solution , usually expressed as percent solids by weight . higher polymer concentrations versus baseline conformal - process concentrations favor polymer cobwebs . the mechanism is multifold . a higher percent solids leads to a higher solution viscosity . high viscosity solutions do not atomize as effectively into small droplets and strands or filaments can be expressed by the spray nozzle . high viscosity also stabilizes these strands so that they are long lived . excess fluid coating on the stents surfaces can be blown off during the spray process by the force of the atomizing gas . this can further form stable strands to interconnect struts . this parameter relates to the temperature of the spray nozzle . higher spray nozzle temperatures , versus baseline conformal - process temperatures favor polymer cobwebs . as coating solution is passed through the spray nozzle , it is heated to the temperature of the spray nozzle . this is advantageous compared to simply heating all of the coating solution before it enters the nozzle as the exposure time of the coating solution to the elevated temperature is short . at higher temperatures , the atomized coating solution loses solvent more rapidly . this elevates the viscosity of the coating solution favoring stand and cobweb formation . the units are temperature in ° c . of the spray nozzle . this parameter relates to the dry nozzle temperature . higher dry nozzle temperatures , versus baseline conformal - process temperatures favor polymer cobwebs . when the stent moves from the spray nozzle to the drying nozzle , the action of warm convected gas removes solvent from the stent . this dries the stent and raises the temperature of the stent itself . when the stent is moved under the spray nozzle , the stent coating can absorb move solvent from the solution that is applied . the higher stent temperature also increases the evaporation rate of solvent from the stent . the drying nozzle can also elevate the temperature in the local environment , including that of the spray nozzle . these factors act to increase cobwebbing with increased dry nozzle temperature . the units are temperature in ° c . of the dry nozzle . this parameter relates to the flow rate of the polymer solution through a spray nozzle for those processes depositing polymer from a spray . higher flow rates versus baseline conformal - process flow rates can favor polymer cobwebs . high spray flow rates can lead to a stent coating that is very wet . this coating can flow and redistribute on the stent . often this leads to pool webs that are regions where a continuous polymer film spans the struts at and near strut junctions . a high atomization pressure can blow this excess coating off to form strands that connect struts . the units are expressed in μg of coating applied per millimeter of stent length per second of coating time . this parameter relates to the atomization pressure for those processes depositing polymer from a spray . higher atomization pressures versus baseline conformal - process atomization pressures favor polymer cobwebs . in spray coating , the atomization serves several purposes . first , it atomizes the solution into droplets . secondly , it propels these droplets at high velocity towards the stent . and third , it significantly dries both the droplets and the coating during spraying . drying the droplets to while they are moving towards the stent raises the percent solids of the droplets that , in turn , raise the viscosity . higher viscosity leads to cobwebbing . higher atomization pressure also leads to higher atomization gas flow rates and velocities . this high gas velocity past the stent can dislodge wet coating , forming strands in between the struts . in most spray coating equipment , the atomization pressure is proportional to the atomization gas velocity and is a useful indicator for the intensity of the atomization . units are those of pressure , psi for instance . this parameter relates to the surface tension of the polymer solution . lower solution surface tension versus baseline conformal - process solution surface tensions favor polymer cobwebs . the formation of cobwebs increases the surface area of the polymer coating . a lower surface tension during coating favors formation of more coating surface area . it increases the stability of strands , filaments , and cobwebs while they are still fluid so that they remain after solvent removal . units on the coating solution are those of surface tension , dyne / cm . when one spray nozzle is used , the stent rotation speed can effect the formation of cobwebbing . more rapid rotation can serve to wind the formed cobwebs and strands around the stent . units are revolutions per minute ( rpm ). one of ordinary skill will recognize that these parameters have a cumulative effect on the polymer &# 39 ; s tendency to form cobwebs . various embodiments comprise modifying any one of or any combination of the volatility , solubility , concentration , spray nozzle , dry nozzle , flow rate , atomization pressure , surface - tension , and rotation parameters in the direction described above to achieve polymer cobwebs . indeed , any one or any combination of these parameters may be modified towards conformal processes ( away from cobweb - forming processes ), if the overall deposition behavior yields polymer cobwebs . furthermore , various embodiments are envisioned in which polymer cobwebs are formed without modifying any one of or any combination of the volatility , solubility , concentration , spray nozzle , dry nozzle , flow rate , atomization pressure , surface - tension , and rotation parameters . a stent with a cobwebbed mesh covering made by a spray process could be used for any stenting indication . there are no limitations on the stent diameter , length , strut pattern , or strut thickness . the stent may be intended for the neurovasculature , carotid , coronary , pulmonary , aorta , renal , biliary , iliac , femoral , popliteal , or other peripheral vasculature . the stent may be balloon expandable or self - expanding . especially suitable materials include ductile polymers appropriate for permanent in vivo use as coatings . elast - eon 2 80a , a silicone urethane , has an ultimate elongation of 520 % and is suitable . other materials include polycarbonate urethanes such as bionate and chronoflex , silicone urethanes such as carbosil and purasil , polyether urethanes such as biomer , silicones , fluorosilicates , poly ( ethylene - co - vinyl alcohol ), poly ( ethylene - co - vinyl acetate ), poly ( butyl methacrylate ), poly ( methacrylate ), poly ( acrylates ), styrene - ethylene / butylene - styrene triblock copolymers , styrene - isobutylene - styrene triblock copolymers , poly ( vinylidene fluoride ), poly ( vinylidene fluoride - co - hexafluoropropylene ), poly ( vinylidene fluoride - co - chlorotrifluoroethylene ), and solvent soluble fluoropolymers . ethylene vinyl alcohol copolymer ( commonly known by the generic name evoh or by the trade name eval ) is functionally a suitable choice of polymer . eval adheres well to the surface of a stent , particularly a stainless - steel surface , and expands on a stent without significant copolymer detachment from the surface . representative examples of polymer families that can be used to coat a medical device in accordance with the present invention include silicone urethanes ; abs resins ; acrylic polymers and acrylic copolymers ; acrylonitrile - styrene copolymers ; alkyd resins ; biomolecules ; cellulose ethers ; celluloses ; copoly ( ether - esters ) ( e . g . peo / pla ); copolymers of polycarboxylic acids and poly - hydroxycarboxylic acids ; copolymers of vinyl monomers with each other and olefins ; cyanoacrylates ; epoxy resins ; ethylene vinyl alcohol copolymer ; ethylene - methyl methacrylate copolymers ; ethylene - vinyl acetate copolymers ; ethylene - α - olefin copolymers ; fluorosilicates ; poly ( acrylates ); poly ( amino acids ); poly ( anhydrides ); poly ( ester amides ); poly ( imino carbonates ); poly ( iminocarbonate ); poly ( methacrylates ); poly ( orthoesters ); poly ( tyrosine arylates ); poly ( tyrosine derive carbonates ); polyacrylates ; polyacrylic acids ; polyacrylonitrile ; polyalkylene oxalates ; polyamides ; polyamino acids ; polyanhydrides ; polycarbonate urethanes ; polycarbonates ; polycarboxylic acids ; polycyanoacrylates ; polydioxanones ; polyester - amides ; polyesters ; polyether urethanes ; polyethers ; poly - hydroxycarboxylic acids ; polyimides ; polyisobutylene and ethylene - α - olefin copolymers ; polyketones ; polymethacrylates ; polyolefins ; polyorthoesters ; polyoxymethylenes ; polyphosphazenes ; polyphosphoester urethanes ; polyphosphoesters ; polyphosphoesters - urethane ; polyurethanes ; polyvinyl alcohols ; polyvinyl aromatics ; polyvinyl esters ; polyvinyl ethers ; polyvinyl ketones ; polyvinylidene halides ; silicone urethanes ; silicones ; solvent - soluble fluoropolymers ; starches ; styrene - ethylene / butylenes - styrene triblock copolymers ; vinyl copolymers vinyl - olefin copolymers ; vinyl halide polymers and copolymers . representative examples of polymers that can be used to coat a medical device in accordance with the present invention include 2 - hydroxyethyl methacrylate ; 2 - hydroxyethyl methacrylate ; biomer ; bionate ; carbosil ; carboxymethyl cellulose ; cellophane ; cellulose ; cellulose acetate ; cellulose acetate butyrate ; cellulose butyrate ; cellulose ethers ; cellulose nitrate ; cellulose propionate ; chronoflex ; collagen ; elast - eon 2 80a ; elastin - collagen ; ethylene vinyl alcohol copolymer ; fibrin ; fibrinogen ; hyaluronic acid ; nylon 66 ; poly ( 3 - hydroxy valerate ); poly ( 3 - hydroxybutyrate ); poly ( 4 - hydroxybutyrate ); poly ( butyl methacrylate ); poly ( d , l - lactide ); poly ( d , l - lactide - co - glycolide ); poly ( d , l - lactide - co - l - lactide ); poly ( ethylene - co - vinyl alcohol ); poly ( glycolic acid ); poly ( glycolide ); poly ( hydroxybutyrate ); poly ( hydroxybutyrate - co - hydroxyvalerate ); poly ( hydroxybutyrate - co - valerate ); poly ( hydroxyvalerate ); poly ( iminocarbonate ); poly ( lactide - co - glycolide ); poly ( l - lactic acid ); poly ( trimethylene carbonate ); polyacrylic acid ; polyacrylic acid ; polyacrylonitrile ; polyanhydride ; polyanhydride ; polycaprolactam ; polycaprolactone ; polydioxanone ; polyethylene glycol ; polyisobutylene ; polyisocyanate ; polyorthoester ; polyorthoester ; polyphosphoester ; polyphosphoester ; polyphosphoester urethane ; polyphosphoester urethane ; polystyrene ; polyurethane ; polyvinyl acetate ; polyvinyl chloride ; polyvinyl esters ; polyvinyl methyl ether ; polyvinyl pyrrolidone ; polyvinylidene chloride ; polyvinylidene fluoride ; purasil ; rayon ; rayon - triacetate ; sodium alginate ; and starch . the polymer coating for use with this invention can comprise a mixture of polymers , such as an intimate mixture of polymer molecules . biologically active polymers are suitable , as well . in some embodiments , the cobweb forming process operates on polymers or mixtures of polymers comprising a drug that can inhibit vascular , smooth muscle cell activity . useful drugs for these devices or coatings include any substance capable of exerting a therapeutic or prophylactic effect in the practice of the present invention . the drug ( s ) can be coated onto the polymer filaments after deposition or can be mixed into the polymer solution before deposition . these bioactive agents can be any agent that is a therapeutic , prophylactic , or diagnostic agent . these agents can have anti - proliferative or anti - inflammatory properties or can have other properties such as antineoplastic , antiplatelet , anti - coagulant , anti - fibrin , anti - thrombonic , antimitotic , antibiotic , antiallergic , antioxidant , as well as cytostatic agents . examples of suitable therapeutic and prophylactic agents include synthetic inorganic and organic compounds , proteins and peptides , polysaccharides and other sugars , lipids , and dna and rna nucleic acid sequences having therapeutic , prophylactic , or diagnostic activities . nucleic acid sequences include genes , antisense molecules that bind to complementary dna to inhibit transcription , and ribozymes . some other examples of other bioactive agents include antibodies , receptor ligands , enzymes , adhesion peptides , blood clotting factors , inhibitors or clot dissolving agents such as streptokinase and tissue plasminogen activator , antigens for immunization , hormones and growth factors , oligonucleotides such as antisense oligonucleotides and ribozymes and retroviral vectors for use in gene therapy . examples of anti - proliferative agents include rapamycin and its functional or structural derivatives , 40 - o -( 2 - hydroxy ) ethyl - rapamycin ( everolimus ), and its functional or structural derivatives , paclitaxel and its functional and structural derivatives . examples of rapamycin derivatives include methyl rapamycin ( abt - 578 ), 40 - o -( 3 - hydroxy ) propyl - rapamycin , 40 - o -[ 2 -( 2 - hydroxy ) ethoxy ] ethyl - rapamycin , and 40 - o - tetrazole - rapamycin . examples of paclitaxel derivatives include docetaxel . examples of antineoplastics and / or antimitotics include methotrexate , azathioprine , vincristine , vinblastine , fluorouracil , doxorubicin hydrochloride ( e . g . adriamycin ® from pharmacia & amp ; upjohn , peapack n . j . ), and mitomycin ( e . g . mutamycin ® from bristol - myers squibb co ., stamford , conn .). examples of such antiplatelets , anticoagulants , antifibrin , and antithrombins include sodium heparin , low molecular weight heparins , heparinoids , hirudin , argatroban , forskolin , vapiprost , prostacyclin and prostacyclin analogues , dextran , d - phe - pro - arg - chloromethylketone ( synthetic antithrombin ), dipyridamole , glycoprotein iib / iiia platelet membrane receptor antagonist antibody , recombinant hirudin , thrombin inhibitors such as angiomax ä ( biogen , inc ., cambridge , mass . ), calcium channel blockers ( such as nifedipine ), colchicine , fibroblast growth factor ( fgf ) antagonists , fish oil ( omega 3 - fatty acid ), histamine antagonists , lovastatin ( an inhibitor of hmg - coa reductase , a cholesterol lowering drug , brand name mevacor ® from merck & amp ; co ., inc ., whitehouse station , n . j . ), monoclonal antibodies ( such as those specific for platelet - derived growth factor ( pdgf ) receptors ), nitroprusside , phosphodiesterase inhibitors , prostaglandin inhibitors , suramin , serotonin blockers , steroids , thioprotease inhibitors , triazolopyrimidine ( a pdgf antagonist ), nitric oxide or nitric oxide donors , super oxide dismutases , super oxide dismutase mimetic , 4 - amino - 2 , 2 , 6 , 6 - tetramethylpiperidine - 1 - oxyl ( 4 - amino - tempo ), estradiol , anticancer agents , dietary supplements such as various vitamins , and a combination thereof . examples of anti - inflammatory agents including steroidal and non - steroidal anti - inflammatory agents include tacrolimus , dexamethasone , clobetasol , combinations thereof . examples of such cytostatic substance include angiopeptin , angiotensin converting enzyme inhibitors such as captopril ( e . g . capoten ® and capozide ® from bristol - myers squibb co ., stamford , conn . ), cilazapril , or lisinopril ( e . g . prinivil ® and prinzide ® from merck & amp ; co ., inc ., whitehouse station , n . j .). an example of an antiallergic agent is permirolast potassium . other therapeutic substances or agents which may be appropriate include alpha - interferon , bioactive rgd , and genetically engineered epithelial cells . the foregoing substances can also be used in the form of prodrugs or co - drugs thereof . the foregoing substances are listed by way of example and are not meant to be limiting . other active agents which are currently available or that may be developed in the future are equally applicable . the dosage or concentration of the bioactive agent required to produce a favorable therapeutic effect should be less than the level at which the bioactive agent produces toxic effects and greater than the level at which non - therapeutic results are obtained . the dosage or concentration of the bioactive agent required to inhibit the desired cellular activity of the vascular region can depend upon factors such as the particular circumstances of the patient ; the nature of the tissues being delivered to ; the nature of the therapy desired ; the time over which the ingredient administered resides at the vascular site ; and if other active agents are employed , the nature and type of the substance or combination of substances . therapeutic effective dosages can be determined empirically , for example by infusing vessels from suitable animal model systems and using immunohistochemical , fluorescent or electron microscopy methods to detect the agent and its effects , or by conducting suitable in vitro studies . standard pharmacological test procedures to determine dosages are understood by one of ordinary skill in the art . some embodiments choose the drug such that it does not contain at least one of or any combination of antiproliferative , antineoplastic , antiinflammatory , antiplatelet , anticoagulant , antifibrin , antithrombin , antimitotic , antibiotic , or antioxidant substances . similarly , some invention embodiments choose the drug such that it does not contain one of or any combination of the drugs or drug classes listed above . the coatings and methods of the present invention have been described with reference to a stent , such as a balloon expandable or self - expandable stent . the use of the coating is not limited to stents , however , and the coating can also be used with a variety of other medical devices . examples of the implantable medical device that can be used in conjunction with the embodiments of this invention include stent - grafts , grafts ( e . g ., aortic grafts ), artificial heart valves , cerebrospinal fluid shunts , pacemaker electrodes , axius coronary shunts and endocardial leads ( e . g ., fineline and endotak , available from guidant corporation ). the underlying structure of the device can be of virtually any design . the device can be made of a metallic material or an alloy such as , but not limited to , cobalt - chromium alloys ( e . g ., elgiloy ), stainless steel ( 316l ), “ mp35n ,” “ mp20n ,” elastinite ( nitinol ), tantalum , tantalum - based alloys , nickel - titanium alloy , platinum , platinum - based alloys such as , e . g ., platinum - iridium alloy , iridium , gold , magnesium , titanium , titanium - based alloys , zirconium - based alloys , or combinations thereof . devices , such as stents , made from bioabsorbable or biostable polymers can also be used with the embodiments of the present invention . “ mp35n ” and “ mp20n ” are trade names for alloys of cobalt , nickel , chromium and molybdenum available from standard press steel co . of jenkintown , pa . “ mp35n ” consists of 35 % cobalt , 35 % nickel , 20 % chromium , and 10 % molybdenum . “ mp20n ” consists of 50 % cobalt , 20 % nickel , 20 % chromium , and 10 % molybdenum . the following method provides standard conformal polymer coatings . its parameters should be modified to cause polymer cobwebbing . in some embodiments , at least one of the parameters discussed above is modified in the following process to cause the process to yield cobwebbed polymer . after the structural members of stent 10 are formed from elastic or pseudoelastic metal , biodegradable polymer , durable polymer , or composite material , the polymeric coating can be applied to stent 10 . various methods can be used to apply the coating such as dipping , roll coating , direct application , wiping , brushing , and spraying . the following application method is provided by way of illustration of a typical process designed to prevent cobwebbing and does not limit the present invention . a spray apparatus , such as efd 780s spray device with valvemate 7040 control system ( manufactured by efd inc ., east providence , r . i . ), can be used to apply a composition to stent 10 . efd 780s spray device is an air - assisted external mixing atomizer . this atomizes the composition into small droplets and uniformly applies the composition to the stent surfaces . the atomization pressure ranges from about 5 psi to about 20 psi . the droplet size depends on such factors as solution viscosity and surface tension and atomization pressure . other types of spray applicators , including air - assisted internal mixing atomizers and ultrasonic applicators , can function to apply the composition . each spraying repetition can be followed by removal of some , most , or all of the solvent ( s ). depending on solvent volatility , the solvent can evaporate essentially upon contact with stent 10 . alternatively , baking the stent at a mild temperature ( e . g ., 60 ° c .) for a suitable duration of time ( e . g ., 2 - 4 hours ) or applying warm air can induce solvent removal . any suitable number of repetitions can be performed to form a coating of a desired thickness or weight . exemplary embodiments illustrating ways to modify typical processes are shown below . a polymer composition comprising kynar flex 2800 can be dissolved in a solvent system comprising acetone , dioxane , and techspray at a ratio of 25 / 50 / 25 by weight . this solution is applied to a medical device such as a stent by using a spray device such as an efd 7805 system with valvemate 7040 control system . the atomization pressure ranges from 5 psi to 25 psi . a polymer composition comprising solef 11010 can be dissolved in a solvent system comprising acetone , dioxane , and techspray at a ratio of 50 / 25 / 25 by weight . this solution is applied to a medical device such as a stent by using a spray device such as an efd 7805 system with valvemate 7040 control system . the spray nozzle temperature ranges from ambient to 45 ° c . a polymer composition comprising solef 21508 can be dissolved in a solvent system comprising acetone / cyclohexanone 90 / 10 by weight . this solution is applied to a medical device such as a stent by using a spray device such as an efd 7805 system with valvemate 7040 control system . the dry nozzle temperature ranges from ambient to 55 ° c . a polymer composition comprising elast - eon 2 80a can be dissolved in a solvent system comprising tetrahydrofuran / dimethylacetamide 75 / 25 by weight . this solution is applied to a medical device such as a stent by using a spray device such as an efd 7805 system with valvemate 7040 control system . the percent polymer solids in solution ranges from 1 % to 6 %. a polymer composition comprising kynar 710 can be dissolved in a solvent system comprising acetone / dimethylacetamide 80 / 20 by weight . this solution is applied to a medical device such as a stent by using a spray device such as an efd 7805 system with valvemate 7040 control system . the spray coating weight per pass ranges from 0 . 14 to 1 . 4 μg / mm sec . after applying the composition to stent 10 and forming the polymeric coating , stent 10 can be integrated into a stent delivery system . about 2 mass % kynar flex 2800 ; dissolved in a mixture of acetone , dioxane , and techspray at a weight ratio of 25 / 50 / 25 the first composition was applied onto the surface of a bare 13 mm tetra stent ( available from guidant corporation ) by spraying and dried to form a cobwebbed stent coating . a spray coater was used , having a 0 . 014 round nozzle maintained at ambient temperature with a feed pressure of about 0 . 2 atm ( about 3 psi ) and an atomization pressure of about 15 psi ( about 1 . 02 atm ). the spray nozzle temperature was at ambient and a coating rate of 0 . 2 μg / mm sec of the wet coating was applied per pass . between the passes , the coating was dried at using a flow of ambient temperature air for about 10 seconds . a total of 20 passes were applied . following the last pass , the coating was baked at about 50 ° c . for about 2 hours . this yielded a cobwebbed , covered stent coating containing about 330 μg of kynar flex 2800 . about 2 mass % solef 11010 ; dissolved in a mixture of acetone , dioxane , and techspray at a weight ratio of 50 / 25 / 25 the first composition was applied onto the surface of a bare 13 mm tetra stent ( available from guidant corporation ) by spraying and dried to form a cobwebbed stent coating . a spray coater was used , having a 0 . 014 round nozzle maintained at ambient temperature with a feed pressure of about 0 . 2 atm ( about 3 psi ) and an atomization pressure of about 15 psi ( about 1 . 02 atm ). the spray nozzle temperature was at ambient and a coating rate of 0 . 23 μg / mm sec of the wet coating was applied per pass . between the passes , the coating was dried at using a flow of ambient temperature air for about 10 seconds . a total of 20 passes were applied . following the last pass , the coating was baked at about 50 ° c . for about 2 hours . this yielded a cobwebbed , covered stent coating containing about 347 μg of solef 11010 . while particular embodiments of the present invention have been shown and described , it will be obvious to those skilled in the art that changes and modifications can be made without departing from the embodiments of this invention in its broader aspects and , therefore , the appended claims are to encompass within their scope all such changes and modifications as fall within the true spirit and scope of the embodiments of this invention . additionally , various embodiments have been described above . for convenience &# 39 ; s sake , combinations of aspects ( such as monomer type or gas flow rate ) composing invention embodiments have been listed in such a way that one of ordinary skill in the art may read them exclusive of each other when they are not necessarily intended to be exclusive . but a recitation of an aspect for one embodiment is meant to disclose its use in all embodiments in which that aspect can be incorporated without undue experimentation . in like manner , a recitation of an aspect as composing part of an embodiment is a tacit recognition that a supplementary embodiment exists in which that aspect is specifically excluded .
this disclosure provides a description of medical devices with polymeric cobwebbing disposed near the surfaces of the medical device . this cobwebbing can contain drug and can enhance the mechanical and chemical function of intraluminal stents . methods of using these devices and methods of preparing the devices are disclosed , as well .