the techniques of the present invention are designed to treat atherosclerosis without damaging the important endothelial layer . once the catheter is positioned , the heating of the atherosclerotic lesion takes little time , in some cases less than one - half second . the power levels are low — in the range of about 1 watt . the catheter is designed to operate while blood continues to flow through the artery . a temperature profile is produced in the arterial wall that necroses or ablates connective tissue , softens waxes and fats , and allows the arterial pressure to more gently act to dilate the artery . frequency of the radiation has a significant affect on the depth of maximum energy deposition . the beamwidth can be selected to be in accord with the size of the lesion . where the lesion ( s ) are asymmetrically disposed in a specific arc of the arterial wall , the energy is directed toward the arc and the angle of focus for the radiator can be adjusted accordingly . this provides much more efficient use of the energy , making the procedure quicker . it also protects the remainder of the healthy tissue from being overheated . therefore , radiation is preferably more specifically tailored to concentrate energy within the atherosclerotic lesion based on the position and depth thereof , as well as the size and shape of the lesion . as more improved information becomes available by ever improving technology about the more precise structure of the lesion , such as with mri and cat scans , the information can be used to further refine predictions when computing temperature profiles through the computerized modeling techniques disclosed , as discussed further in regard to the computer simulation program . furthermore , the test assembly of the parent of this application may be used to quite realistically test the instrument using damaged arterial segments so that extensive experience and training can be obtained prior to use . as a general background . fig1 discloses the progressive nature of atherosclerosis with a variable time line in terms of age . artery 1110 is initially free of lesions or fatty tissue so that lumen 1114 is completely open . between very roughly the age of 15 to 30 , fatty streaks 1115 begin to develop as shown by artery 1120 . these fatty streaks may disappear as indicated by the double arrows between artery 1110 and 1120 . thus , the body has the ability to reabsorb fatty streaks , to some extent . over age 30 , waxy and fibrous tissue or atheroma 1118 forms as indicated in artery 1130 . the atheroma 1118 , or atherosclerotic lesion , shown in artery 1130 , is in the uncomplicated state , or non - thrombotic state , that leaves some lumen , however narrow . the waxy , and especially the fibrous tissue does not normally disappear as frequently as did fatty streaks 1115 . without assistance of some type , the body has less ability to reabsorb such tissue . at some time , very roughly in the age range of 40 to 80 , a complicated lesion 1124 , with plaque that typically also includes calcification , as indicated in artery 1140 may occur . the body tends to have little ability to reabsorb the calcification although some pharmacological treatments exist wherein the goal is to assist the body to effect reabsorption of calcified plaque . complicated lesion 1124 is considered complicated because it may be hemorrhaged , ulcered , calcified , or thrombogenic , and may produce a heart attack , or myocardial infarction , due to blockage of blood flow . in this case , thrombus or blood clot 1122 has formed to block artery 1140 . therefore , as the disease slowly progresses , trauma to the endothelial layer may occur that results in a complication . for instance , if blood is then exposed to collagen tissue that typically encapsulates the plaque , and / or for the numerous other reasons discussed hereinabove , blood clot such as thrombus 1122 may develop that closes the artery lumen and results in a heart attack due to the heart muscle not receiving sufficient , or any , blood flow . obviously , it is preferable that treatment begin prior to the complicated or occlusive stage of artery 1140 . such treatment may be directed to slowing down the atherosclerotic processes involved and may involve dieting , monitored exercising , lowering cholesterol , decreasing blood pressure , and the like . if the lumen needs to be dilated to obtain sufficient blood flow to the heart muscles , and pharmacological means are unable to provide suitable relief , means as discussed hereinafter may be used to dilate the lumen while attempting to maintain the important healthy aspects of the artery . it will be observed that often , as shown , atherosclerotic lesions are asymmetrical , as indicated in artery 1130 . in accord with the present invention , the healthy tissue not affected by atherosclerosis should be protected and not be placed under stress . any healthy tissues that are damaged in the process of dilating the lumen may become involved in processes of restenosis wherein a relatively rapid reclosure of the artery may occur within one year or so after the dilation procedure . according to the present invention , plaque is preferably heated so as to soften and melt it . after heating , the plaque volume or volume of the lesion may be somewhat reduced and some plaque components , such as the fatty elements , may perhaps be reabsorbed to a certain degree . the heating also necroses or ablates connective tissue so that the arterial lumen can dilate due to natural arterial pressure . without the aid of connective tissue , flesh loses connective strength and may be similar to a paste or gel in overall tensile strength . care also needs to be taken to not ablate too much tissue surrounding the artery . if the artery has insufficient strength , it may become subject to problems of aneurysms . as noted previously , the possibility of aneurysms can also be a long term problem associated with balloon angioplasty treatment . apparently , simply opening the diameter of the lumen is not , in itself , necessarily the cause of restenosis . by avoiding damage to healthy tissue including the endothelium , it is expected that this technique will alleviate some , and perhaps many , of the processes of restenosis . however , it will be recognized that essentially dilation procedures are simply delay procedures that permit improved blood circulation while , hopefully , the underlying causes of the atherosclerosis , which may be many causes , are alleviated . however , because restenosis tends to proceed at a much faster pace than the underlying problem of atherosclerosis , restenosis remains a very significant barrier to successful long term treatment of atherosclerosis . it is therefore a basic goal of the present invention to alleviate problems of restenosis while dilating the artery . fig1 discloses the general make up of a healthy arterial vessel wall in greater detail disclosing the cellular layers of tissues and provides , very approximately , the width in microns of the cellular layers in an average healthy vessel wall . the values of the width of the vessel wall may change significantly for a vessel wall having an atherosclerotic lesion in it . plaque tends to somehow make its way into and to build up within the intimal and / or medial layers , apparently due to numerous processes that may underlie the atherosclerosis . the intimal layer includes the endothelium layer wherein endothelial cell 1212 is indicated and an additional layer of cellular tissue 1214 . as discussed previously , blood does not clot when in contact with the endothelial layer but has a tendency to do so when it comes into contact with many other types of tissues such as those found within plaque , e . g ., collagen or connective tissue . such tissues are highly thrombotic . protection of the endothelial layer is therefore very important and , if it remains healthy , will probably aid in preventing or slowing of numerous of the processes of restenosis , as well as the processes involved in atherosclerosis . internal elastic membrane 1216 separates the intimal layer from medial layer that includes smooth muscle cells 1222 . adventitial layer 1224 provides for lymph drainage and blood flow within the arterial wall . the lumen is located adjacent intimal layer and defined by the endothelium , in the health artery . atherosclerotic lesions are found within the vessel wall , generally in the intimal or medial layers . it is desirable to apply heat to the lesion without traumatizing the surrounding tissues , including the endothelium and adventitial layers . where possible , it is desirable to protect the healthy intimal layer and / or medial layers when the lesion has not formed therein . therefore , a system is necessary for developing a controllable temperature profile that maximizes heat within the lesion and wherein the temperature drops off quickly outside the lesion to avoid damage to healthy tissue . referring now to fig1 the major components of system 10 disclose a preferred embodiment of the present invention for treating atherosclerosis . generally , system 10 includes a millimeter wave / microwave power source , a catheter transmission line in the form of a waveguide , coaxial cable or combination of the two , and an antenna / radiator located at the end of the catheter . another type of catheter without a microwave transmission line is also shown as an alternative embodiment in fig1 and is discussed hereinafter . power source 12 is capable of producing up to 10 watts at a controlled power level . however , generally the power required may be considerably less if the atherosclerotic lesion is asymmetrically oriented and depending on the size thereof . it is presently anticipated that heating will generally be sufficiently effected at levels closer to about one watt , depending on the volume of the lesion . the subsequently shown test results are normally based on an antenna power of one watt or less . power level control 14 is used to adjust the antenna power to the desired level . power source 12 supplies power at the desired frequency , which as shown hereinafter , can be used to control the temperature profile . selected frequencies for the present invention , depending on the application as discussed hereinafter , are in a range from 2 ghz to 300 ghz . it is presently anticipated that a separate power source would preferably be used or required for each frequency selected . pulse duration control 15 provides a pulse that controls the time that antenna power is applied . in the present embodiment , pulse duration control 15 is arranged to be pulsed with a desired pulse duration of from 0 . 1 to 10 seconds , with the accuracy of the pulse duration controlled within 2 %. as will be seen subsequently , the pulse duration was less than about 0 . 5 seconds during the tests for anticipated volumes of lesion size which were for asymmetrically spaced atheromas . as discussed subsequently , the necessary power can be applied more quickly , or efficiently , if the asymmetrical nature of the typical atherosclerotic lesion is taken into consideration . not only is heating time reduced thereby limiting treatment time to a desirable minimum , but also healthy tissue is spared . the pulse duration may be increased or decreased as necessary and precision of the pulse length could be narrowed , if desired although the small 2 % variation in pulse duration is not anticipated to significantly affect the thermal profile produced . directional coupler 16 is used to match impedances for more efficient application of power to the antenna . forward / reflected power monitor 18 detects if a mismatch has occurred such that power is not being radiated from the antenna with sufficient efficiency . in that case , power will not be radiated efficiently and therefore power source 12 may be shut down automatically . catheter 20 provides a means of directing energy from power source 12 to antenna 22 . at the higher range of frequencies from approximately 25 - 30 ghz to300 ghz , it is likely that a flexible waveguide would provide the most efficient means of power delivery . at the lower frequencies , from approximately 2 ghz to 25 - 30 ghz , a coaxial cable will probably be preferable for efficiency of power delivery . in some cases , it may be desirable to have a coaxial cable for a portion of catheter 20 formed of coaxial cable and a portion formed of waveguide . if that proves to be desirable as may occur for flexibility purposes , cost , convenience or other reasons , then an impedance matching transition member , such as transition member 24 , may be used to connect between the coaxial cable portion and the waveguide portion . in yet another embodiment , such as that discussed in the embodiment of fig1 , it may be preferable to locate the millimeter wave source directly behind the antenna , thereby reducing transmission line losses . antenna design is also preferably made dependent of the selected frequency of operation . for operation in the higher range of frequencies , the presently preferred embodiment of the invention would use a radically beveled open ended waveguide antenna , as shown in fig2 and discussed hereinafter . the radically beveled antenna produces a radiation beam that is directed to a selected arc of the lumen . for frequencies at the lower end of the frequency range , disk loaded monopole antennas , as shown in fig3 have proven to be effective . disk loaded monopole antennas are discussed in some detail in the parent to this application , which application is incorporated by reference herein . at the low end of the frequency range , antennas tend to radiate much more broadly . therefore , such antennas may be more suitable when the cross - sectional distribution of lesion ( s ) is of the type sometimes referred to as a circumferential lesion that yield a central lumen completely surrounded by a circumferentially distributed lesion . more commonly , an eccentric atheroma is found that yields an eccentric lumen . for this reason , the radically beveled open ended antenna that operates in the higher range of frequencies may be preferable . for this and other reasons discussed hereinafter , a choice of 95 ghz was made for the initial test program in which selected arteries , in vitro , will be heated via a transcatheter antenna . it will be noted that the eccentric lumen may be subdivided further into categories including a slitlike or circular lumen with the circular lumen being positioned eccentrically within the cross - section of the artery . there are numerous variations in between , depending largely on the size of the arc of the lesion . the slitlike lumen may have a lengthwise diameter almost as wide and the original lumen . therefore , adjustment of the beamwidth of the antenna may be used , as discussed subsequently , or some additional rotation of the antenna may be used , to heat the desired portion or all of the atheroma . fig2 discloses a presently preferred radiator for the higher frequency range of from about 25 - 30 ghz to 300 ghz in the form of a radically beveled circular waveguide antenna 200 . waveguide material 210 is preferably a low loss ceramic material that is suitably flexible for use in a catheter . the waveguide antenna and waveguide preferably have a diameter 224 of about two millimeters and is circular . metallic sheath 214 is cut and removed to provide for a radical bevel 212 . metallic sheath 214 conforms and surrounds waveguide material 210 . the angle of bevel 212 affects the width of the directional beam 218 , indicated in dash , produced by antenna 200 so that a smaller angle with respect to the longitudinal axis of the antenna produces a wider beam . a minimum and maximum angle may be used depending on variables related to the losses at beveled interface 220 . as indicated , directional beam 218 is directed radially outwardly from beveled interface 220 . as discussed hereinafter in regards to the computational simulation , beam 218 , depending on the type of antenna , may be a focused beam , a spreading beam in one direction , or a spherically spreading beam . the beam of the waveguide antenna may be a focussed beam without significant spreading although , for illustrative purposes only , some spreading is indicated as may be possible to produce depending on the angled cut of the bevel . a selected beamwidth with appropriate spreading tendencies is desirable and necessarily depends on the size and location of the lesion in the wall . tip 216 may be formed of waveguide material 210 and preferably extends past radical bevel 212 in metallic circular cross - sectioned sheath 214 . tip 216 may also be formed of a different dielectric material selected for loading purposes . however , construction of antenna 200 may be simplified somewhat if the same waveguide material 210 is used . a medically acceptable nonthrombogenic material is used to form sheath 222 of the catheter . federal regulations presently require use of a new catheter for each procedure rather than allowing sterilization and reuse of the same catheters . this factor may make it possible to provide for variations in the catheters and the catheter antennas to match the particular usage of size and shape of the lesion without any substantial increase in cost . fig3 discloses a double disk loaded monopole antenna 300 in accord with the present invention . the general construction features of such an antenna are covered in some detail in the parent of this application so that only the basic features are covered herein . antenna 300 is essentially simply a smaller antenna than the antenna disclosed in the parent , and reference is made to the earlier patent that is incorporated herein by reference . antenna 300 is connected to coaxial cable portion 310 . coaxial cable 310 comprises an outer metallic conductor 312 and a centrally located conductor 314 . insulator material such as teflon ® or other suitable material forms the core 316 of coaxial cable 310 and also preferably extends into antenna 300 . to limit current flow along the catheter , metal choke 318 is employed . insulative jacket 320 is provided on the catheter but is cut off at the beginning of metal choke 318 so that radiation may occur , mainly from the discontinuities of antenna 300 starting at the beginning of gap 322 . gap 322 is related to the frequency of operation . the second and third discontinuities include tuning disk 324 and disk 326 . tuning disk 324 may be used to adjust the center frequency of operation of the antenna so as to flatten the response over the bandwidth of operation , which tends to be fairly broad . antenna 300 is preferably used for lower frequencies such as the range from 2 ghz to 25 or 30 ghz radiation proceeds outwardly in all directions from antenna 300 and therefore antenna 300 is preferably used for treatment of circumferentially disposed atherosclerotic lesions . referring to fig4 in operation at frequencies above 40 ghz , most energy is deposited within the atherosclerotic lesion and little energy will pass into and beyond the adventitial layer because of rapid decay of the electromagnetic wave . the frequency used in the chart of fig4 is 95 ghz . the maximum temperature rise for the example of fig4 occurs at about 132 microns as indicated by heavy line 410 which represents the temperature profile as a function of depth . the heating time is 0 . 5 seconds and the volume heated is 5 cubic millimeters . the antenna power is 1 watt . a focused beam is used and the maximum temperature increase is approximately 12 degrees for the example of fig4 . the material used for testing is beef heart muscle . keeping all variables the same except frequency , the maximum temperature rise for the situation of fig5 occurs at 246 microns , therefore indicating the significant effect that changing only frequency has on the temperature profile . for a focused beam antenna , power absorption decreases as exp (− 2αr ) where α is the attenuation constant , and r is the distance from the antenna . this exponential decay is indicated by the thin line 412 in fig4 that indicates the relative deposition rate of energy as a percentage . for a very broadly radiating antenna , power absorption decays as exp (− 2αr )/ r 2 . the decay is more rapid because of spherical beam spreading resulting in the r 2 term in the denominator . therefore , when a broad beam radiator is used for radiating an asymmetrically disposed lesion , only a portion of the radiated energy is used so that generally only a portion of the lesion is illuminated . the extraneous energy is wasted or produces heating of non - diseased tissue or proximal blood . except for circumferentially diffused lesions , a focused beam is therefore preferred . in addition to electromagnetic heat deposition , thermal conduction plays a critical role in obtaining the desired temperature profile within the arterial wall . at any depth within the wall , thermal equilibrium is reached when the heat gained by electromagnetic deposition is equal to the heat lost by the heat loss mechanisms . at the internal surface of the artery . i . e ., the endothelial layer , heat lost by conduction and convection to the flowing blood as well as heat lost by conduction to the outer layer of the transcatheter antenna , will prevent any significant temperature rise . as indicated in fig4 heat rise for the first 20 microns is zero . the maximum heat rise over the endothelial layer , of approximately 30 microns , is only about 2 degrees centigrade . at shallow depths within the intimal layer , temperatures are depressed by strong thermal conduction to the blood due to the relatively short distance thereto . at deeper depths , temperatures rise until a depth of maximum temperature is reached . in the chart of fig4 the maximum temperature is reached at 132 microns from the surface of the vessel . by adjusting the frequency , beam width , pulse time , and power , the maximum temperature can be placed at the center of the atherosclerotic lesion . at depths beyond the lesion , temperatures drop because electromagnetic deposition , as indicated by thin line 412 , is significantly diminished . therefore , in the example of fig4 the adventitial layer and much of the muscle tissue of the medial layer is well preserved . in the example of fig5 where all the controlled variables are the same , i . e ., power delivered , pulse duration , and antenna bandwidth , the maximum temperature occurs at 246 microns as indicated by temperature profile thick line 510 , which is typically well beyond the intima and into the media where many lesions occur . thin curve 512 discloses a more flattened energy deposition curve . in both cases , the important endothelial layer is well preserved . temperature profiles can be customized to the size , shape , and type of the lesion . the controllable factors that determine the temperature profile are the following : ( 1 ) antenna power delivered , ( 2 ) pulse length , ( 3 ) frequency , and ( 4 ) antenna design / beamwidth control . a computer program simulation has been written that calculates the three dimensional isothermal contours for a given frequency , power level , pulse duration , antenna type , tissue complex permittivity and tissue constants . examples are shown in the isothermal type printouts of fig6 - fig8 . it will be noted that the program can be used with heterogenous tissues that are typical with atherosclerotic lesions , although in the present examples the tissue is assumed to be homogenous . it is anticipated that testing with actual atherosclerotic tissue in the test unit will refine the values used . e . g ., for thermal conductivity and conductivity . as well , test information about the particular situation available or that may become available in the future due to advances such as refined mri photos may be of value in refining the data for particular cases . in fig6 , and 8 all variables are kept constant except frequency , although the isothermal regions viewed in fig8 are twice as large . the type of printout shown is a sectionalized isothermal profile although other types of printouts could be used or different views could be projected . these particular views are shown for example only . in fig6 the computer simulation uses a frequency of 95 ghz . in fig7 the selected frequency is 40 ghz and in fig8 the selected frequency is 15 ghz . the large plot on the left in each figure shows the heating of a cube of myocardium with half of the cube cut away in the z direction to show the isothermal profiles in the x - y plane . the eight individual cross - sections shown on the right are artificially expanded in the y direction so that the isothermal profiles in the x - y plane can be observed . it will be seen that the results from the computer simulation are similar to that shown in the physical testing as per the charts of fig4 and fig5 . an increase in frequency , keeping all other variables constant , tends to move the center of the position of maximum temperature closer to the antenna . this is seen by reviewing regions 616 , 716 , and 816 that of the respective fig6 , and 8 that indicate regions having temperature increases between 15 and 20 degrees kelvin . the regions of relatively moderate increases , i . e . 612 , 712 , and 812 for temperature increases between 5 and 10 degrees kelvin , and 614 , 714 , and 814 for temperature increases between 10 and 15 show a somewhat similar shift in the same direction . the coolest regions are those of 610 , 710 , and 810 that reflect regions having a temperature increase less than 5 degrees kelvin . the individual cell size selected for this particular display is 100 microns on a side ( 200 microns on a side in fig8 ) and therefore provides an overview of a relatively large area for easy viewing of the overall effects throughout the simulated lesion volume . the entire field size is about 1800 microns on a side for fig6 and fig7 and 3600 microns for fig8 . in the isothermal segments of fig6 and fig7 the side in the x direction is 1800 microns wide and the side in the y direction is 900 microns . if desired , much smaller regions , such as the approximately 30 micron depth of the endothelium , could be emphasized in greater detail to provide a picture of heating in the endothelial , intimal , medial , or any other portion of the arterial wall . however , it will be noted that the larger scales are quite useful when an overview is desired . fig9 is a printout that provide some relatively detailed feedback from the computer simulation regarding this region and any of about 50 different sections , as discussed hereinafter , although the focus of the simulation printout can be varied as desired . other graphs such as the temperature profile versus depth for various times during the heating period may be printed out . the plots may be in color . additional information may be printed on each plot including values such as cell size , final temperature profile , type of antenna radiation , number of cubic millimeters at various selected temperature ranges , total energy in the cube after the power pulse , antenna radiated power , the number of computational cells illuminated , and so forth . comparing information regarding fig6 , and 8 , the volume of material having a 10 ° c .- 15 ° c . rise is greater for 40 ghz and less at both 95 ghz and 15 ghz . the time of the pulse in each case was 299 milliseconds . for short duration times of power application , the blood temperature at the surface of the lesion near the antenna rises with increasing frequency . the maximum temperature in the lesion moves to shallower depths with increasing frequency . also the maximum temperature in the lesion increases with increasing frequency . one basic premise shown from fig6 , and 8 is that heat contours can be significantly customized by frequency selection alone . further customization is accomplished by selection of power level , duration of power delivery , and antenna type . the computer simulation can readily show the effects of such changes . the simulation results can be compared with information obtained from the test setup as discussed in the parent wherein temperature profiles , blood flow , type of vein , and so forth can be realistically determined , even prior to in vivo testing . in a presently preferred embodiment of the simulation , a computational “ myocardium ” or heart tissue cube having a size that correlates to a region of tissue to be ablated is given the electrical and thermal characteristics of in - vivo myocardium . this selection is made for convenience and could be given the characteristics of plaque and encapsulating tissue . the characteristics can be specifically tailored for different areas of the cube or can be given average values . the cube or region or other shape selected as desired to be analyzed is subdivided into computational cells . in this simulation a cube of simulated myocardium is divided into 8000 small cubes with each cube being a computational cell . the instantaneous heat of one arbitrary computational cell in the cube is given by : δq rf is the heat added due to absorption of microwave energy ; ∫ δq hc is the net heat added or lost by the cell from heat conduction ; and t c is the new cell temperature in ° c . ; each cell is assumed to be a cube with six faces . the heat energy transferred through each face for one time increment is given by : ∂ t /∂ r is the temperature gradient from the center of one cube to the next ; and the electric field intensity in a cell is given by : e ^ l = e ^ nl  e - γrl r l a 10 ê 1 is the electric field intensity resulting from the the radiation at the feed point of the antenna ; ê 01 is related to the relative magnitude and phase of radiation from the phase center of the antenna ; and r 1 is the distance from the antenna phase center to the center of a cell . a = 0 for a focused beam , 1 for a spreading beam in one dimension , and 2 for a spherically spreading beam . as discussed previously , the results from the simulation can be plotted in many ways to show the size and shape of the projected isothermal volumes . fig9 shows a different presentation wherein the temperature vs . time is given for each of 50 layers of 20 micron thickness with each layer being represented by a separate line . although any of the lines could be displayed individually , only lines 1 - 4 , the top layers , and line 16 , the hottest layer are clearly visible and are marked . each line represents a thickness of 20 microns . the heating time is one second . the frequency is 15 ghz . the volume heated is 9 . 4 cubic millimeters . as can be seen from this graph , layer 16 would have been heated by about 16 degrees centigrade and is about 320 microns into the arterial wall which would probably typically be in the medial layer of the artery . it will be noted that the first one or two layers that would be the endothelium would remain less than about 5 degrees centigrade , in this projection . the program may also be altered to accept the desired heat contours as the input . by working backwards from a desired thermogenic profile , the program could be used to select the most appropriate choice of frequency , power level , duration of power delivery , antenna beamwidth from a particular selection of antennas , and other factors as discussed herein . fig1 discloses oscillator chip catheter 1000 as another embodiment of the present invention . in this embodiment , a direct current power supply 1010 is used to supply power through catheter 1020 to one or more mmic chips 1030 that may use a radiating antenna 1040 such as a waveguide antenna , disk - loaded monopole antenna , or other antenna . the mmic chips preferably reside in the catheter &# 39 ; s distal end adjacent to the radiating element . currently , mmic technology allows for cylindrical diameter dimensions of about 2 . 76 millimeters plus a thin sheath , which an excellent size that allows for convenient positioning of catheter 1020 . the presently available chips cover the preferred range of frequencies , i . e ., 2 ghz to 300 ghz , over a range from about 50 ghz to about 110 ghz . chips operating in the lower frequencies of about 50 ghz presently offer more power per chip . to achieve greater than one watt of power delivered to radiating element 1040 , if necessary , two or more mmic chips may be sequentially connect together . the chips may be physically connected with microstrip 1050 . numerous variations and methods of operation may be used with the present invention . for instance , the catheter of the present invention may be used with other catheters and / or means to orient the catheter or may be built into other types of catheters . the present catheter may be modified to include simple orientation means . for instance , on the sheath side of the waveguide antenna , a simple resistivity sensor might be added that operates at a much lower frequency and with very low current but is directive and will sense the difference in resistivity of the arterial wall with or without an atheroma so as to quickly detect position and orient the device . although the present device is preferable used instead of an angioplasty balloon , it has advantages that may also make it useful in combination with an angioplasty balloon , if desired , e . g ., the ability to direct heat towards an asymmetrically positioned lesion . while the preferred embodiment antennas are disclosed in accord with the law requiring disclosure of the presently preferred embodiment of the invention , other types of antennas may also be used . therefore , the foregoing disclosure and description of the invention are illustrative and explanatory thereof , and various changes in the method steps and also the details of the apparatus may be made within the scope of the appended claims without departing from the spirit of the invention .
method and apparatus are provided to treat atherosclerosis wherein the artery is partially closed by dilating the artery while preserving the vital and sensitive endothelial layer thereof . microwave energy having a frequency from 3 ghz to 300 ghz is propagated into the arterial wall to produce a desired temperature profile therein at tissue depths sufficient for thermally necrosing connective tissue and softening fatty and waxy plaque while limiting heating of surrounding tissues including the endothelial layer and / or other healthy tissue , organs , and blood . the heating period for raising the temperature a potentially desired amount , about 20 ° c . within the atherosclerotic lesion may be less than about one second . in one embodiment of the invention , a radically beveled waveguide antenna is used to deliver microwave energy at frequencies from 25 ghz or 30 ghz to about 300 ghz and is focused towards a particular radial sector of the artery . because the atherosclerotic lesions are often asymmetrically disposed directable or focussed heating preserves healthy sectors of the artery and applies energy to the asymmetrically positioned lesion faster than a non - directed beam . a computer simulation predicts isothermic temperature profiles for the given conditions and may be used in selecting power , pulse duration , beam width , and frequency of operation to maximize energy deposition and control heat rise within the atherosclerotic lesion without harming healthy tissues or the sensitive endothelium cells .