Can I take a year off during a masters program? I am a second year part-time masters degree student at NYU, with a full time job. My life is pretty simple and boring in NY. I was looking for opportunities, and yesterday it happened. I was accepted as an "intern" for one of Hillary Clinton's organizations in some other state. And there is this other organization that will be financially supporting me for 6 month. Later, I am expected to get a part/full time job there. This is life time opportunity, big adventure, lots of sacrifice and commitment.. 

My question is: Can I take a year off during grad school in order to be able to work full time in some other state?
As Bill Barth suggests, you really need to check with your department and institutional policies. Every school, and often departments in the same school, can have very different policies.

The fact that you're a master's student, and therefore presumably enrolled in classes rather than actively conducting research, probably will make things easier, as leaves of absence are less disruptive during coursework than in research (for instance, it's harder to "postpone" a grant for a project to enable a student to take a semester or year off).