no reply from potential supervisor I know there are already many similar questions posted on this website, but I need someone to comment on my email to potential advisors. 
I should mention that I've been sending emails to potential supervisors for over one month now, and very few of them have replied, which makes me think there's something wrong with my email. Also, I personalize these emails for each professor and investigate their research before sending the email.

Here is an example:

Dear Professor X,
I am a graduate student of X from X University, highly interested in X and have recently published a paper in X. I have achieved a great deal of training and experiences in the field of targeted drug delivery. I’ve enjoyed reading your papers and ideas such as "assessing the impact of anti-PEG IgM on the biological performance of nanoparticles and using chelating zinc ions" and "optimisation of pH during nanoprecipitation to increase insulin loading into PLGA-PEG nanoparticles". Your research is best compatible with my research interest because I am looking for positions that I can both exploit my skills in drug delivery and further explore the field of X. I am very eager to know your opinion regarding my case in joining your research team as a PhD candidate for fall 2020. For more information, I have attached my resume as a PDF file. I look forward to hearing from you soon.

Sincerely,
XX

I would appreciate your comments about the email.
Like user avid, I used to get several of these and they were easy to ignore. Even retired for several years, I get a few. Some ask me to join my lab (which I never had). Others are from wildly different fields. Straight to trash, or even junk.
You seem to have avoided some of the pitfalls, provided that your field really is relevant to what the professor does.
But you ask too much. You've flooded the professor and implicitly asked for some analysis of all that is there. The CV as a pdf is overkill, for example. It is too early for that. Many recipients will stop reading after your first or second sentence. You will be immediately dumped with the others that are even more off base.

Dear Professor Buffy
I am inquiring whether you are accepting students at this time. If so, I'd like to discuss with you my qualifications and interest. I can provide whatever background information you need to evaluate my candidacy.
If you will have a position open in the near future I'd like to apply.
Sincerely panipiridin

You will be more likely to get some reply. Even if it is just &quot;sorry&quot;, letting you know to move on. But if the reply is as simple as &quot;say more&quot; then you know you have an audience.
But it requires very little on the part of the busy professor, so is more likely to succeed. Don't ask for a lot in a contact email.
But, of course, do your homework first, so that you don't wind up wasting anyone's time, including your own. Make sure you have an idea of what that prof is really interested in. Prowl their web pages. Read a paper or two. Be ready to answer simple questions about that area of research.

I assume in the above that you are in a place/field in which early acceptance by a professor is required for admission to a program. That isn't universally the case, so understand the overall system too. For example, in the US in mathematics or CS it is normally the case that you first get accepted by the university. Then you start some coursework. Then you find an advisor. But here you get to have the conversation in their office and don't need (and shouldn't use) email.