Multiple submission of same work for different audiences I have research work that has been conducted and is at the stage where it is worth disseminating to the research community. It is somewhat cross-discipline in nature, and involves some technical contributions and is also of interest to a set of end users who are completely non-technical.

The problem is that, having attempted previous submissions, it has become painfully clear that neither community seems to appreciate quite the same issues as the other. Thus, a single paper aimed at addressing all the issues from both perspectives ends up being perhaps lacklustre, and apparently unappealing from both sides. This is partly due to constraints on paper length, which prevent adequate detail for all aspects of the paper, and also the fact that fundamentally large portions of the paper end up being targeted towards an audience that is not present for the given journal.

Therefore, I was wondering if I could adopt the approach whereby a high-level paper is written targeting the end users of the development and submitted to an appropriate journal, and a second paper which covers the technical aspects in detail without trying to cover the aspects necessary for the end-user audience. Considering that both papers will present the same results, is this an acceptable approach to publication?
This is actually something my group also deals with extensively. A lot of the work we do is focused on improving existing computational methods to improve their efficiency or extend their range. A lot of the time, the actual work done is of very little interest to the end-user audience, but quite significant from a computer science perspective. So a lot of our recent work has been divided in exactly the manner you propose: we present the basics of the method and some end-user applications in papers geared toward the application community, and specialized papers for the methodology that are directed toward the CS community.

The main thing to remember is that the publications should stand independently of one another as much as possible. Some overlap will of course be inevitable here, but you should strive to make the "stories" they tell as distinct as possible.