Funding faculty position for a spouse My wife is looking for a faculty position. It seems its not so easy to get a position in biology though she is doing postdoc at top 5 genetics programs in USA. I am wondering if I can offer a school funding equivalent to her pay for 5 years plus some more for research? I am wondering if good schools will be interested in it? Why I want to do is because at least my wife will cool down and will live a normal life!
If I may paraphrase your question, it sounds like you would like to use money to tilt the playing field of a faculty search in your wife’s favor. You would like to know if your plan can work.

Sadly for you, but happily for our society and the health of our academic institutions, this has zero chance of working. Faculty positions at respected universities are offered based on merit - that is exactly why those places are respected in the first place. If your wife has what it takes to get a job offer, she will get it without the need for any subsidies. If she doesn’t, she won’t get it with or without your subsidy offer. At all US universities where people I know and respect work, the only conceivable reactions to your offer would be bafflement at your cluelessness, if not outright derision and anger at your presumption to be able to influence their hiring process by offering money. Conversely, any institution that would seriously entertain your offer (and I suppose there may exist some third-rate, cash-strapped universities that might) is one where I would not advise your wife to take a job.

To be clear, even respectable institutions may put a price tag on their reputations. If you were to offer, say, a donation of 50 million dollars conditioned on your wife being offered a faculty job (you’d better ask for her to get it with tenure in that case), and your wife was reasonably well-qualified, I don’t know for sure but I’m guessing that there are departments that might find such an offer tempting. A university can do a lot of good things with such a large sum of money, probably enough to offset the risk of any reputational harm they might suffer. But five years’ salary and change? That’s a complete non-starter.

Anyway, good luck to your wife in her job search.