Submitting a new paper just after another was accepted by the same journal In my subfield, there is a highly regarded journal. I just finished a manuscript, which I thought would be suitable and ‘good enough’ for this journal.
Coincidentally, another manuscript that I had originally submitted to the journal two years ago, after long periods of waiting, revision, etc. just got accepted by this journal.

Should I adapt my plans in any way? Does it seem like I am ‘journal-hogging’ or gaming the system if I submit a new paper literally days after the last one has been accepted?
With one paper every two years I don’t think you will be seen as gaming the system.

Go ahead and submit.