UniProtKB/Swiss-Prot : 75 Diabetes mellitus, insulin-dependent, 22: A multifactorial disorder of glucose homeostasis that is characterized by susceptibility to ketoacidosis in the absence of insulin therapy. Clinical features are polydipsia, polyphagia and polyuria which result from hyperglycemia-induced osmotic diuresis and secondary thirst. These derangements result in long-term complications that affect the eyes, kidneys, nerves, and blood vessels.
MalaCards based summary : Diabetes Mellitus, Insulin-Dependent, 22, is also known as iddm22. An important gene associated with Diabetes Mellitus, Insulin-Dependent, 22 is CCR5 (C-C Motif Chemokine Receptor 5 (Gene/Pseudogene)). Affiliated tissues include kidney and eye.
Disease Ontology : 12 A type 1 diabetes mellitus that has material basis in mutation of the CCR5 gene on chromosome 3p21.31.
Related Diseases for Diabetes Mellitus, Insulin-Dependent, 22