I currently have 5 . 10 Anasazi velcro . I used to have two pair of anasazi lace up . My general footsize is 10 . 5 and fit my original 2 pair leather ! !! Very important at size 10 . They were tight . but when they eventually broke in they fit my feet like they were built specifically for me . My new lace up have synthetic and are not meant to stretch so I aired on the side of caution and bought 10 . 5 . At first I thought I may have made a mistake but after some use , they are also really great fit . Comfortable , while maintaining precision . The bonus is the comfort for longer pitches . My feet don ' t like la sportiva anything . Either the toe box is wrong or the ankle digs in to my heels like you wouldnt believe . Only other shoe I truly liked or tried was Scarpa Vapor V . And those I downsized a full 1 . 5 sizes . 5 . 10 are great and fit me as they should without really having to downsize . Synthetic fit my feet to true , and leather stretch so downsize a half size . Hope anything helps .