이종은 / LEE , Jong Eun 
 Department of Anatomy , Yonsei University College of Medicine , 
 BK 21 Project for Medical Science 
 + 82 - 2 - 2228 - 1646 
 jelee @ yuhs . ac 
 Bs . , Biochemistry of Yonsei University , 1983 
 Stanford Univ . , Medical School , Dept . of Anesthesia 
 Post Doc , 1996 . - 1998 
 여성 생명 과학 포럼 , 부회장 , 2014 - 현재 
 한국 뇌신경 과 학회 , 재무 이사 , 2013 - 현재 
 대한 해부 학회 , 연구윤리 위원장 & 해외 교류 위원 , 2003 - 현재 
 대한 해부 학회 , 총무 이사 , 2014 - 현재 
 Anatomy and Cell Biology ( ACB ) , Executive Editor , 1985 - 현재 
 1 . The characteristics of functional stem cells expressing ADC gene and application 
 2 . Therapeutic efficacy of ADC - NSCs against various CNS diseases 
 3 . Neural differentiation mediated by arginine metabolome 
 4 . Repair mechanisms in maintaining the blood brain barrier ( BBB ) integrity of endothelial cells after ischemic injured brain blood vessel with anti - oxidant therapy 
 5 . The therapeutic mechanisms of post stroke dementia and alzheimer ’ s disease 
 Stroke , Spinal cord injury , dementia , ex vivo culture system 
 1 ) Induction of ischemic preconditioning and focal ischemia 
 2 ) Complete transection spinal cord injury model 
 3 ) Cortical neural stem cell , neuron , astrocyte , primary culture , Ex vivo culture 
 4 ) siRNA , miRNA , lentivirus , retroviral gene transfer 
 5 ) Confocal microscopy , immunohistochemistry 
 6 ) FACS analysis , apoptosis assay , HPLC assay 
 7 ) Morphometric measurement of brain edema and infarct volume 
 8 ) Methylation specific polymerase chain reaction assay 
 9 ) Behavioral test : open - field test , surface right reflex test , rotarod test , Limb Placing test , BBB test , Passive avoidance test , Water Maze , Radial Maze , Y Maze 등 
 10 ) Paraffin emdedding section , freezing section 
 의대 신관 146 호 
 의대 신관 136 , 137 호 
 Name : 김재환 / Tel : 2228 - 1659 / E - mail : JHKIM 74 @ yuhs . ac 
 2 . Kiran Kumar Bokara , Kihyo Kwon , Yoon Mi Nho , Won Taek Lee , Kyung Ah Park , Jong Eun Lee : Retroviral expression of arginine decarboxylase attenuates oxidative burden in mouse cortical neuronal stem cells . Stem Cells Dev . 20 ( 3 ) : 527 - 537 , 2011 
 3 . Yu Mi Park 1 , 2 , Won Taek Lee 1 , Kiran Kumar Bokara 1 , Su Kyung Seo 1 , 2 , Seung Hwa Park 3 , Jae Hwan Kim , Kyung Ah Park 1 , Jong Eun Lee 1 , 2 , *: The mutifaceted effects of agmatine on functional recovery after spinal cord injury through modulation of BMP - 2 / 4 / 7 expressions in neurons and glial cells . PLoS One 8 ( 2 ) : e 53911 , 2013 
 4 . Juhyun Song , Bo Eun Hur , Kiran Kumar Bokara , Wonsuk Yang , Hyun Jin Cho , Kyung Ah Park , Won Taek Lee , Kyoung Min Lee , Jong Eun Lee : Agmatine improves cognitive dysfunction and prevents cell death in Streptozotocin - induced Alzheimer rat model . Yonsei Medical Journal 55 ( 3 ) : 689 - 699 , 2014 
 5 . Juhyun Song , So Mang Kang , Won Taek Lee , Kyung Ah Park , Kyoung Min Lee , Jong Eun Lee : The beneficial effect of melatonin in brain endothelial cells against oxygen - glucose deprivation followed by reperfusion ( OGD / R ) induced injury . Oxidative Medicine and Cellular Longevity 2014 : 639531 , 2014