1 H NMR ( 400 MHz , CD 3 OD ) δ 9 . 12 ( br s , 1 H ) , 8 . 92 ( s , 1 H ) , 8 . 83 - 8 . 74 ( br s , 1 H ) , 8 . 48 ( s , 1 H ) , 8 . 18 ( d , J = 9 . 0 Hz , 1 H ) , 7 . 74 ( dd , J = 9 . 0 , 2 . 0 Hz , 1 H ) , 6 . 51 ( s , 1 H ) , 5 . 58 - 5 . 46 ( m , 1 H ) , 4 . 29 ( dd , J = 11 . 8 , 5 . 3 Hz , 1 H ) , 3 . 80 - 3 . 66 ( br m , 1 H ) , 3 . 66 - 3 . 52 ( br m , 1 H ) , 2 . 79 - 2 . 66 ( m , 1 H ) , 2 . 60 ( s , 3 H ) , 2 . 42 - 2 . 27 ( br m , 1 H ) , 2 . 13 - 2 . 00 ( br m , 1 H ) , 1 . 77 - 1 . 63 ( br m , 1 H ) , 1 . 28 ( br d , J = 5 . 5 Hz , 3 H ) .