well at least for PvE at long as youre not targeted by the enemy , i find that if theyre not actively pursuing you then theyre usually busy predicting your teammates AI instead of your moves , so they never respond in time to dodge or guard against those type of movesi . e me and vegeta on a team vs frieza , if vegeta and frieza are fighting , ideally you wanna wait til theyre right in the middle of moves so they will still be in that spot when the move ends , but with the moves that track its not as important . basically all you wanna do is wait til vegetas doing like a galick gun or a combo or some shit , and then queue up the spirit bomb for example , and by the time frieza recovers or begins to attack vegeta again , before he even finishes his move theres a spirit bomb behind him and he will almost always get stuck in it , same goes for the other giant ki blasts but super spirit bomb is pretty obviously the best , biggest , arguably strongest and for the least amount of ki , 3 bars or 300 , compared to 400 for death ball and 500 for supernova