So I have a couple of questions . My doctor is considering putting me on a regiment of Estriadol , Bicalutimide replacement for Spiro because I reacted badly to it , finasteride , and possibly a progestin she mentioned it but hasnt brought it up since so I think she intends to do so later on . Do you see any issues with this ? Interactions or anything ? Since stopping Spiro after one month I have had my transition continue . I had breast buds happen after two weeks of being on only estradiol and finasteride , month one and a half total , and I still dont get random or morning erections and there is seemingly no sperm when I finish . Breast growth has continued and I can tell they ' re there under my shirts now . So my question is , do you think that adding Bicalutimide to my regiment is still necessary if things are continuing ? Finally , since the breast growth I mentioned in the last question is happening , do you think I should be pushing to get on a progestin soon ?