< 110 > Industry Academic Cooperation Foundation , Hallym University < 120 > Pharmaceutical composition for treating cerebral ischemia containing phosphoglycerate mutase 1 fusion protein < 130 > HallymU - SYCHOI _ Tat _ PGAM 1 _ BrainIschemia < 160 > 2 < 170 > KoPatentIn 3 . 0 < 210 > 1 < 211 > 792 < 212 > DNA < 213 > Artificial Sequence < 220 > < 223 > polynucleotide coding Tat - PGAM 1 fusion protein < 400 > 1 aggaagaagc ggagacagcg acgaagaatg gccgcctaca aactggtgct gatccggcac 60 ggcgagagcg catggaacct ggagaaccgc ttcagcggct ggtacgacgc cgacctgagc 120 ccggcgggcc acgaggaggc gaagcgcggc gggcaggcgc tacgagatgc tggctatgag 180 tttgacatct gcttcacctc agtgcagaag agagcgatcc ggaccctctg gacagtgcta 240 gatgccattg atcagatgtg gctgccagtg gtgaggactt ggcgcctcaa tgagcggcac 300 tatgggggtc taaccggtct caataaagca gaaactgctg caaagcatgg tgaggcccag 360 gtgaagatct ggaggcgctc ctatgatgtc ccaccacctc cgatggagcc cgaccatcct 420 ttctacagca acatcagtaa ggatcgcagg tatgcagacc tcacagaaga tcagctaccc 480 tcctgtgaga gtctgaagga tactattgcc agagctctgc ccttctggaa tgaagaaata 540 gttccccaga tcaaggaggg gaaacgtgta ctgattgcag cccatggcaa cagcctccgg 600 ggcattgtca agcatctgga gggtctctct gaagaggcta tcatggagct gaacctgccg 660 actggtattc ccattgtcta tgaattggac aagaacttga agcctatcaa gcccatgcag 720 tttctggggg atgaagagac ggtgcgcaaa gccatggaag ctgtggctgc ccagggcaag 780 gccaagaagt ga 792 < 210 > 2 < 211 > 265 < 212 > PRT < 213 > Artificial Sequence < 220 > < 223 > Tat - PGAM 1 fusion protein < 400 > 2 Arg Lys Lys Arg Arg Gln Arg Arg Arg Leu Glu Met Ala Ala Tyr Lys 1 5 10 15 Leu Val Leu Ile Arg His Gly Glu Ser Ala Trp Asn Leu Glu Asn Arg 20 25 30 Phe Ser Gly Trp Tyr Asp Ala Asp Leu Ser Pro Ala Gly His Glu Glu 35 40 45 Ala Lys Arg Gly Gly Gln Ala Leu Arg Asp Ala Gly Tyr Glu Phe Asp 50 55 60 Ile Cys Phe Thr Ser Val Gln Lys Arg Ala Ile Arg Thr Leu Trp Thr 65 70 75 80 Val Leu Asp Ala Ile Asp Gln Met Trp Leu Pro Val Val Arg Thr Trp 85 90 95 Arg Leu Asn Glu Arg His Tyr Gly Gly Leu Thr Gly Leu Asn Lys Ala 100 105 110 Glu Thr Ala Ala Lys His Gly Glu Ala Gln Val Lys Ile Trp Arg Arg 115 120 125 Ser Tyr Asp Val Pro Pro Pro Pro Met Glu Pro Asp His Pro Phe Tyr 130 135 140 Ser Asn Ile Ser Lys Asp Arg Arg Tyr Ala Asp Leu Thr Glu Asp Gln 145 150 155 160 Leu Pro Ser Cys Glu Ser Leu Lys Asp Thr Ile Ala Arg Ala Leu Pro 165 170 175 Phe Trp Asn Glu Glu Ile Val Pro Gln Ile Lys Glu Gly Lys Arg Val 180 185 190 Leu Ile Ala Ala His Gly Asn Ser Leu Arg Gly Ile Val Lys His Leu 195 200 205 Glu Gly Leu Ser Glu Glu Ala Ile Met Glu Leu Asn Leu Pro Thr Gly 210 215 220 Ile Pro Ile Val Tyr Glu Leu Asp Lys Asn Leu Lys Pro Ile Lys Pro 225 230 235 240 Met Gln Phe Leu Gly Asp Glu Glu Thr Val Arg Lys Ala Met Glu Ala 245 250 255 Val Ala Ala Gln Gly Lys Ala Lys Lys 260 265