SEQUENCE LISTING < 110 > Applied Research Systems ARS Holding N . V . < 120 > FSH Mutants < 130 > 1115 WO < 160 > 5 < 170 > PatentIn version 3 . 3 < 210 > 1 < 211 > 92 < 212 > PRT < 213 > Homs sapiens < 400 > 1 Ala Pro Asp Val Gln Asp Cys Pro Glu Cys Thr Leu Gln Glu Asn Pro 1 5 10 15 Phe Phe Ser Gln Pro Gly Ala Pro Ile Leu Gln Cys Met Gly Cys Cys 20 25 30 Phe Ser Arg Ala Tyr Pro Thr Pro Leu Arg Ser Lys Lys Thr Met Leu 35 40 45 Val Gln Lys Asn Val Thr Ser Glu Ser Thr Cys Cys Val Ala Lys Ser 50 55 60 Tyr Asn Arg Val Thr Val Met Gly Gly Phe Lys Val Glu Asn His Thr 65 70 75 80 Ala Cys His Cys Ser Thr Cys Tyr Tyr His Lys Ser 85 90 < 210 > 2 < 211 > 111 < 212 > PRT < 213 > Homo sapiens < 400 > 2 Asn Ser Cys Glu Leu Thr Asn Ile Thr Ile Ala Ile Glu Lys Glu Glu 1 5 10 15 Cys Arg Phe Cys Ile Ser Ile Asn Thr Thr Trp Cys Ala Gly Tyr Cys 20 25 30 Tyr Thr Arg Asp Leu Val Tyr Lys Asp Pro Ala Arg Pro Lys Ile Gln 35 40 45 Lys Thr Cys Thr Phe Lys Glu Leu Val Tyr Glu Thr Val Arg Val Pro 50 55 60 Gly Cys Ala His His Ala Asp Ser Leu Tyr Thr Tyr Pro Val Ala Thr 65 70 75 80 Gln Cys His Cys Gly Lys Cys Asp Ser Asp Ser Thr Asp Cys Thr Val 85 90 95 Arg Gly Leu Gly Pro Ser Tyr Cys Ser Phe Gly Glu Met Lys Glu 100 105 110 < 210 > 3 < 211 > 111 < 212 > PRT < 213 > Artificial < 220 > < 223 > beta subunit mutant E 55 N / V 57 T < 400 > 3 Asn Ser Cys Glu Leu Thr Asn Ile Thr Ile Ala Ile Glu Lys Glu Glu 1 5 10 15 Cys Arg Phe Cys Ile Ser Ile Asn Thr Thr Trp Cys Ala Gly Tyr Cys 20 25 30 Tyr Thr Arg Asp Leu Val Tyr Lys Asp Pro Ala Arg Pro Lys Ile Gln 35 40 45 Lys Thr Cys Thr Phe Lys Asn Leu Thr Tyr Glu Thr Val Arg Val Pro 50 55 60 Gly Cys Ala His His Ala Asp Ser Leu Tyr Thr Tyr Pro Val Ala Thr 65 70 75 80 Gln Cys His Cys Gly Lys Cys Asp Ser Asp Ser Thr Asp Cys Thr Val 85 90 95 Arg Gly Leu Gly Pro Ser Tyr Cys Ser Phe Gly Glu Met Lys Glu 100 105 110 < 210 > 4 < 211 > 96 < 212 > PRT < 213 > Artificial < 220 > < 223 > alpha subunit insertion mutant GNFT < 400 > 4 Ala Pro Asp Gly Asn Phe Thr Val Gln Asp Cys Pro Glu Cys Thr Leu 1 5 10 15 Gln Glu Asn Pro Phe Phe Ser Gln Pro Gly Ala Pro Ile Leu Gln Cys 20 25 30 Met Gly Cys Cys Phe Ser Arg Ala Tyr Pro Thr Pro Leu Arg Ser Lys 35 40 45 Lys Thr Met Leu Val Gln Lys Asn Val Thr Ser Glu Ser Thr Cys Cys 50 55 60 Val Ala Lys Ser Tyr Asn Arg Val Thr Val Met Gly Gly Phe Lys Val 65 70 75 80 Glu Asn His Thr Ala Cys His Cys Ser Thr Cys Tyr Tyr His Lys Ser 85 90 95 < 210 > 5 < 211 > 96 < 212 > PRT < 213 > Artificial < 220 > < 223 > alpha subunit insertion mutant GNRT < 400 > 5 Ala Pro Asp Gly Asn Arg Thr Val Gln Asp Cys Pro Glu Cys Thr Leu 1 5 10 15 Gln Glu Asn Pro Phe Phe Ser Gln Pro Gly Ala Pro Ile Leu Gln Cys 20 25 30 Met Gly Cys Cys Phe Ser Arg Ala Tyr Pro Thr Pro Leu Arg Ser Lys 35 40 45 Lys Thr Met Leu Val Gln Lys Asn Val Thr Ser Glu Ser Thr Cys Cys 50 55 60 Val Ala Lys Ser Tyr Asn Arg Val Thr Val Met Gly Gly Phe Lys Val 65 70 75 80 Glu Asn His Thr Ala Cys His Cys Ser Thr Cys Tyr Tyr His Lys Ser 85 90 95