< 110 > Research & Business Foundation SUNGKYUNKWAN UNIVERSITY < 120 > An inductive plasmid display system for selecting a plasmid encoding a protein with specific properties expressed < 130 > MP 18 - 157 < 160 > 40 < 170 > KoPatentIn 3 . 0 < 210 > 1 < 211 > 101 < 212 > PRT < 213 > Artificial Sequence < 220 > < 223 > Cfa Int - N < 400 > 1 Cys Leu Ser Tyr Asp Thr Glu Ile Leu Thr Val Glu Tyr Gly Phe Leu 1 5 10 15 Pro Ile Gly Lys Ile Val Glu Glu Arg Ile Glu Cys Thr Val Tyr Thr 20 25 30 Val Asp Lys Asn Gly Phe Val Tyr Thr Gln Pro Ile Ala Gln Trp His 35 40 45 Asn Arg Gly Glu Gln Glu Val Phe Glu Tyr Cys Leu Glu Asp Gly Ser 50 55 60 Ile Ile Arg Ala Thr Lys Asp His Lys Phe Met Thr Thr Asp Gly Gln 65 70 75 80 Met Leu Pro Ile Asp Glu Ile Phe Glu Arg Gly Leu Asp Leu Lys Gln 85 90 95 Val Asp Gly Leu Pro 100 < 210 > 2 < 211 > 39 < 212 > PRT < 213 > Artificial Sequence < 220 > < 223 > Cfa Int - C < 400 > 2 Met Val Lys Ile Ile Ser Arg Lys Ser Leu Gly Thr Gln Asn Val Tyr 1 5 10 15 Asp Ile Gly Val Glu Lys Asp His Asn Phe Leu Leu Lys Asn Gly Leu 20 25 30 Val Ala Ser Asn Cys Phe Asn 35 < 210 > 3 < 211 > 105 < 212 > PRT < 213 > Artificial Sequence < 220 > < 223 > Npu Int - N < 400 > 3 Ala Glu Tyr Cys Leu Ser Tyr Glu Thr Glu Ile Leu Thr Val Glu Tyr 1 5 10 15 Gly Leu Leu Pro Ile Gly Lys Ile Val Glu Lys Arg Ile Glu Cys Thr 20 25 30 Val Tyr Ser Val Asp Asn Asn Gly Asn Ile Tyr Thr Gln Pro Val Ala 35 40 45 Gln Trp His Asp Arg Gly Glu Gln Glu Val Phe Glu Tyr Cys Leu Glu 50 55 60 Asp Gly Ser Leu Ile Arg Ala Thr Lys Asp His Lys Phe Met Thr Val 65 70 75 80 Asp Gly Gln Met Leu Pro Ile Asp Glu Ile Phe Glu Arg Glu Leu Asp 85 90 95 Leu Met Arg Val Asp Asn Leu Pro Asn 100 105 < 210 > 4 < 211 > 36 < 212 > PRT < 213 > Artificial Sequence < 220 > < 223 > Npu Int - C < 400 > 4 Met Ile Lys Ile Ala Thr Arg Lys Tyr Leu Gly Lys Gln Asn Val Tyr 1 5 10 15 Asp Ile Gly Val Glu Arg Asp His Asn Phe Ala Leu Lys Asn Gly Phe 20 25 30 Ile Ala Ser Asn 35 < 210 > 5 < 211 > 126 < 212 > PRT < 213 > Artificial Sequence < 220 > < 223 > Ssp Int - N < 400 > 5 Ala Glu Tyr Cys Leu Ser Phe Gly Thr Glu Ile Leu Thr Val Glu Tyr 1 5 10 15 Gly Pro Leu Pro Ile Gly Lys Ile Val Ser Glu Glu Ile Asn Cys Ser 20 25 30 Val Tyr Ser Val Asp Pro Glu Gly Arg Val Tyr Thr Gln Ala Ile Ala 35 40 45 Gln Trp His Asp Arg Gly Glu Gln Glu Val Leu Glu Tyr Glu Leu Glu 50 55 60 Asp Gly Ser Val Ile Arg Ala Thr Ser Asp His Arg Phe Leu Thr Thr 65 70 75 80 Asp Tyr Gln Leu Leu Ala Ile Glu Glu Ile Phe Ala Arg Gln Leu Asp 85 90 95 Leu Leu Thr Leu Glu Asn Ile Lys Gln Thr Glu Glu Ala Leu Asp Asn 100 105 110 His Arg Leu Pro Phe Pro Leu Leu Asp Ala Gly Thr Ile Lys 115 120 125 < 210 > 6 < 211 > 36 < 212 > PRT < 213 > Artificial Sequence < 220 > < 223 > Ssp Int - C < 400 > 6 Met Val Lys Val Ile Gly Arg Arg Ser Leu Gly Val Gln Arg Ile Phe 1 5 10 15 Asp Ile Gly Leu Pro Gln Asp His Asn Phe Leu Leu Ala Asn Gly Ala 20 25 30 Ile Ala Ala Asn 35 < 210 > 7 < 211 > 120 < 212 > PRT < 213 > Artificial Sequence < 220 > < 223 > Rma Int - N < 400 > 7 Cys Leu Ala Gly Asp Thr Leu Ile Thr Leu Ala Asp Gly Arg Arg Val 1 5 10 15 Pro Ile Arg Glu Leu Val Ser Gln Gln Asn Phe Ser Val Trp Ala Leu 20 25 30 Asn Pro Gln Thr Tyr Arg Leu Glu Arg Ala Arg Val Ser Arg Ala Phe 35 40 45 Cys Thr Gly Ile Lys Pro Val Tyr Arg Leu Thr Thr Arg Leu Gly Arg 50 55 60 Ser Ile Arg Ala Thr Ala Asn His Arg Phe Leu Thr Pro Gln Gly Trp 65 70 75 80 Lys Arg Val Asp Glu Leu Gln Pro Gly Asp Tyr Leu Ala Leu Pro Arg 85 90 95 Arg Ile Pro Thr Ala Ser Thr Pro Thr Leu Thr Glu Ala Glu Leu Ala 100 105 110 Leu Leu Gly His Leu Ile Gly Asp 115 120 < 210 > 8 < 211 > 36 < 212 > PRT < 213 > Artificial Sequence < 220 > < 223 > Rma Int - C < 400 > 8 Trp Asp Pro Ile Val Ser Ile Glu Pro Asp Gly Val Glu Glu Val Phe 1 5 10 15 Asp Leu Thr Val Pro Gly Pro His Asn Phe Val Ala Asp Asn Ile Ile 20 25 30 Ala Gly Asn Ser 35 < 210 > 9 < 211 > 118 < 212 > PRT < 213 > Artificial Sequence < 220 > < 223 > Ppu Int - N < 400 > 9 Cys Ile Ser Lys Phe Ser His Ile Met Trp Ser His Val Ser Lys Pro 1 5 10 15 Leu Phe Asn Phe Ser Ile Lys Lys Ser His Met His Asn Gly Asn Lys 20 25 30 Asn Ile Tyr Gln Leu Leu Asp Gln Gly Glu Ala Phe Ile Ser Arg Gln 35 40 45 Asp Lys Lys Thr Thr Tyr Lys Ile Arg Thr Asn Ser Glu Lys Tyr Leu 50 55 60 Glu Leu Thr Ser Asn His Lys Ile Leu Thr Leu Arg Gly Trp Gln Arg 65 70 75 80 Cys Asp Gln Leu Leu Cys Asn Asp Met Ile Thr Thr Gln Ile Gly Phe 85 90 95 Glu Leu Ser Arg Lys Lys Lys Tyr Leu Leu Asn Cys Ile Pro Phe Ser 100 105 110 Leu Cys Asn Phe Glu Thr 115 < 210 > 10 < 211 > 33 < 212 > PRT < 213 > Artificial Sequence < 220 > < 223 > Ppu Int - C < 400 > 10 Leu Ala Asn Ile Asn Ile Ser Asn Phe Gln Asn Val Phe Asp Phe Ala 1 5 10 15 Ala Asn Pro Ile Pro Asn Phe Ile Ala Asn Asn Ile Ile Val His Asn 20 25 30 Ser < 210 > 11 < 211 > 106 < 212 > PRT < 213 > Artificial Sequence < 220 > < 223 > Cwa Int - N < 400 > 11 Cys Leu Ser Tyr Asp Thr Glu Ile Leu Thr Val Glu Tyr Gly Ala Met 1 5 10 15 Tyr Ile Gly Lys Ile Val Glu Glu Asn Ile Asn Cys Thr Val Tyr Thr 20 25 30 Val Asp Lys Asn Gly Phe Val Tyr Thr Gln Thr Ile Ala Gln Trp His 35 40 45 Asn Arg Gly Glu Gln Glu Ile Phe Glu Tyr Asp Leu Glu Asp Gly Ser 50 55 60 Lys Ile Lys Ala Thr Lys Asp His Lys Phe Met Thr Ile Asp Gly Glu 65 70 75 80 Met Leu Pro Ile Asp Glu Ile Phe Glu Lys Asn Leu Asp Leu Lys Gln 85 90 95 Val Val Ser His Pro Asp Asp Tyr Leu Val 100 105 < 210 > 12 < 211 > 37 < 212 > PRT < 213 > Artificial Sequence < 220 > < 223 > Cwa Int - C < 400 > 12 Met Val Lys Ile Ile Gly Cys Arg Ser Leu Gly Thr Gln Lys Val Tyr 1 5 10 15 Asp Ile Gly Val Glu Lys Asp His Asn Phe Leu Leu Ala Asn Gly Ser 20 25 30 Ile Ala Ser Asn Cys 35 < 210 > 13 < 211 > 118 < 212 > PRT < 213 > Artificial Sequence < 220 > < 223 > Cra 505 Int - N < 400 > 13 Cys Leu Ser Tyr Glu Thr Glu Val Leu Thr Leu Glu Tyr Gly Phe Val 1 5 10 15 Pro Ile Gly Glu Ile Val Asn Lys Gln Met Val Cys Thr Val Phe Ser 20 25 30 Leu Asn Asp Ser Gly Asn Val Tyr Thr Gln Pro Ile Gly Gln Trp His 35 40 45 Asp Arg Gly Val Gln Asp Leu Tyr Glu Tyr Cys Leu Asp Asp Gly Ser 50 55 60 Thr Ile Arg Ala Thr Lys Asp His Lys Phe Met Thr Thr Gln Gly Glu 65 70 75 80 Met Val Pro Ile Asp Glu Ile Phe His Gln Gly Trp Glu Leu Val Gln 85 90 95 Val Ser Gly Ile Ser Lys Leu Val Gln Gln Arg Thr Leu Pro Phe Ile 100 105 110 Ile Val Asp Arg Lys Leu 115 < 210 > 14 < 211 > 37 < 212 > PRT < 213 > Artificial Sequence < 220 > < 223 > Cra 505 Int - C < 400 > 14 Met Val Lys Ile Val Ser Arg Arg Tyr Leu Gly Lys Ala Asp Val Tyr 1 5 10 15 Asp Ile Gly Val Ala Lys Asp His Asn Phe Ile Ile Lys Asn Gly Leu 20 25 30 Val Ala Ser Asn Cys 35 < 210 > 15 < 211 > 99 < 212 > PRT < 213 > Artificial Sequence < 220 > < 223 > Csp 8801 Int - N < 400 > 15 Cys Leu Ser Tyr Asp Thr Glu Ile Leu Thr Val Glu Tyr Gly Ala Ile 1 5 10 15 Pro Ile Gly Lys Val Val Glu Glu Asn Ile Asp Cys Thr Val Tyr Thr 20 25 30 Val Asp Lys Asn Gly Phe Val Tyr Thr Gln Asn Ile Ala Gln Trp His 35 40 45 Leu Arg Gly Gln Gln Glu Val Phe Glu Tyr Tyr Leu Asp Asp Gly Ser 50 55 60 Ile Leu Arg Ala Thr Lys Asp His Gln Phe Met Thr Leu Glu Gly Glu 65 70 75 80 Met Leu Pro Ile His Glu Ile Phe Glu Thr Gly Leu Glu Leu Lys Lys 85 90 95 Ile Lys Ile < 210 > 16 < 211 > 37 < 212 > PRT < 213 > Artificial Sequence < 220 > < 223 > Csp 8801 Int - C < 400 > 16 Met Val Lys Ile Val Ser Tyr Arg Ser Leu Gly Lys Gln Phe Val Tyr 1 5 10 15 Asp Ile Gly Val Ala Gln Lys His Asn Phe Leu Leu Ala Asn Gly Ser 20 25 30 Ile Ala Ser Asn Cys 35 < 210 > 17 < 211 > 99 < 212 > PRT < 213 > Artificial Sequence < 220 > < 223 > Csp 0110 Int - N < 400 > 17 Cys Leu Ser Tyr Asp Thr Glu Ile Leu Thr Val Glu Tyr Gly Pro Met 1 5 10 15 Pro Ile Gly Lys Ile Val Glu Glu Asn Ile Asn Cys Ser Val Tyr Thr 20 25 30 Val Asn Lys Asn Gly Phe Val Tyr Thr Gln Ser Ile Ala Gln Trp His 35 40 45 His Arg Gly Glu Gln Glu Val Phe Glu Tyr Tyr Leu Glu Asp Gly Glu 50 55 60 Thr Ile Arg Ala Thr Lys Asp His Lys Phe Met Thr Thr Glu Gly Lys 65 70 75 80 Met Leu Pro Ile Asp Glu Ile Phe Glu Asn Asn Leu Asp Leu Lys Lys 85 90 95 Leu Thr Val < 210 > 18 < 211 > 37 < 212 > PRT < 213 > Artificial Sequence < 220 > < 223 > Csp 0110 Int - C < 400 > 18 Met Val Lys Ile Ile Glu Arg Arg Ser Leu Gly Lys Gln Asn Val Tyr 1 5 10 15 Asp Ile Gly Val Glu Lys Asp His Asn Phe Leu Leu Ser Asn Asn Leu 20 25 30 Ile Ala Ser Asn Cys 35 < 210 > 19 < 211 > 104 < 212 > PRT < 213 > Artificial Sequence < 220 > < 223 > Mcht Int - N < 400 > 19 Cys Leu Ser Tyr Asp Thr Gln Ile Leu Thr Val Glu Tyr Gly Ala Val 1 5 10 15 Ala Ile Gly Glu Ile Val Glu Lys Gln Ile Glu Cys Thr Val Tyr Ser 20 25 30 Val Asp Glu Asn Gly Tyr Val Tyr Thr Gln Pro Ile Ala Gln Trp His 35 40 45 Asn Arg Gly Glu Gln Glu Val Phe Glu Tyr Leu Leu Glu Asp Gly Ala 50 55 60 Thr Ile Arg Ala Thr Lys Asp His Lys Phe Met Thr Asp Glu Asp Gln 65 70 75 80 Met Leu Pro Ile Asp Gln Ile Phe Glu Gln Gly Leu Glu Leu Lys Gln 85 90 95 Val Glu Val Leu Gln Pro Val Phe 100 < 210 > 20 < 211 > 37 < 212 > PRT < 213 > Artificial Sequence < 220 > < 223 > Mcht Int - C < 400 > 20 Met Val Lys Ile Val Arg Arg Gln Ser Leu Gly Val Gln Asn Val Tyr 1 5 10 15 Asp Ile Gly Val Glu Lys Asp His Asn Phe Cys Leu Ala Ser Gly Glu 20 25 30 Ile Gln Ser Asn Cys 35 < 210 > 21 < 211 > 100 < 212 > PRT < 213 > Artificial Sequence < 220 > < 223 > Maer Int - N < 400 > 21 Cys Leu Gly Gly Glu Thr Leu Ile Leu Thr Glu Glu Tyr Gly Leu Leu 1 5 10 15 Pro Ile Ala Lys Ile Val Ser Glu Glu Ile Asn Cys Thr Val Tyr Thr 20 25 30 Val Asp Gln Asn Gly Phe Val Tyr Ser Gln Pro Ile Ser Gln Trp His 35 40 45 Glu Arg Gly Leu Gln Glu Val Phe Glu Tyr Thr Leu Glu Asn Gly Gln 50 55 60 Thr Ile Gln Ala Thr Lys Asp His Lys Phe Met Thr Ser Asp Gly Glu 65 70 75 80 Met Leu Ala Ile Asp Thr Ile Phe Glu Arg Gly Leu Asp Leu Lys Ser 85 90 95 Ser Asp Phe Ser 100 < 210 > 22 < 211 > 37 < 212 > PRT < 213 > Artificial Sequence < 220 > < 223 > Maer Int - C < 400 > 22 Met Val Lys Ile Ile Gly Arg Gln Ser Leu Gly Arg Lys Pro Val Tyr 1 5 10 15 Asp Ile Gly Val Glu Lys Asp His Asn Phe Leu Leu Gly Asn Gly Leu 20 25 30 Ile Ala Ser Asn Cys 35 < 210 > 23 < 211 > 102 < 212 > PRT < 213 > Artificial Sequence < 220 > < 223 > Asp Int - N < 400 > 23 Cys Leu Ser Tyr Asp Thr Glu Val Leu Thr Val Glu Tyr Gly Phe Val 1 5 10 15 Pro Ile Gly Glu Ile Val Glu Lys Gly Ile Glu Cys Ser Val Phe Ser 20 25 30 Ile Asn Asn Asn Gly Ile Val Tyr Thr Gln Pro Ile Ala Gln Trp His 35 40 45 His Arg Gly Lys Gln Glu Val Phe Glu Tyr Cys Leu Glu Asp Gly Ser 50 55 60 Ile Ile Lys Ala Thr Lys Asp His Lys Phe Met Thr Gln Asp Gly Lys 65 70 75 80 Met Leu Pro Ile Asp Glu Ile Phe Glu Gln Glu Leu Asp Leu Leu Gln 85 90 95 Val Lys Gly Leu Pro Glu 100 < 210 > 24 < 211 > 37 < 212 > PRT < 213 > Artificial Sequence < 220 > < 223 > Asp Int - C < 400 > 24 Met Ile Lys Ile Ala Ser Arg Lys Phe Leu Gly Val Glu Asn Val Tyr 1 5 10 15 Asp Ile Gly Val Arg Arg Asp His Asn Phe Phe Ile Lys Asn Gly Leu 20 25 30 Ile Ala Ser Asn Cys 35 < 210 > 25 < 211 > 112 < 212 > PRT < 213 > Artificial Sequence < 220 > < 223 > Oli Int - N < 400 > 25 Cys Leu Ser Tyr Asn Thr Glu Val Leu Thr Val Glu Tyr Gly Pro Leu 1 5 10 15 Pro Ile Gly Lys Ile Val Asp Glu Gln Ile His Cys Arg Val Tyr Ser 20 25 30 Val Asp Glu Asn Gly Phe Val Tyr Thr Gln Ala Ile Ala Gln Trp His 35 40 45 Asp Arg Gly Tyr Gln Glu Ile Phe Ala Tyr Glu Leu Ala Asp Gly Ser 50 55 60 Val Ile Arg Ala Thr Lys Asp His Gln Phe Met Thr Glu Asp Gly Gln 65 70 75 80 Met Phe Pro Ile Asp Glu Ile Trp Glu Lys Gly Leu Asp Leu Lys Lys 85 90 95 Leu Pro Thr Val Gln Asp Leu Pro Ala Ala Val Gly Tyr Thr Val Ser 100 105 110 < 210 > 26 < 211 > 37 < 212 > PRT < 213 > Artificial Sequence < 220 > < 223 > Oli Int - C < 400 > 26 Met Val Lys Ile Val Arg Arg Gln Ser Leu Gly Val Gln Asn Val Tyr 1 5 10 15 Asp Ile Gly Val Glu Lys Asp His Asn Phe Cys Leu Ala Ser Gly Glu 20 25 30 Ile Ala Ser Asn Cys 35 < 210 > 27 < 211 > 101 < 212 > PRT < 213 > Artificial Sequence < 220 > < 223 > Aov Int - N < 400 > 27 Cys Leu Ser Ala Asp Thr Glu Ile Leu Thr Val Glu Tyr Gly Phe Leu 1 5 10 15 Pro Ile Gly Glu Ile Val Gly Lys Ala Ile Glu Cys Arg Val Tyr Ser 20 25 30 Val Asp Gly Asn Gly Asn Ile Tyr Thr Gln Ser Ile Ala Gln Trp His 35 40 45 Asn Arg Gly Glu Gln Glu Val Phe Glu Tyr Thr Leu Glu Asp Gly Ser 50 55 60 Ile Ile Arg Ala Thr Lys Asp His Lys Phe Met Thr Thr Asp Gly Glu 65 70 75 80 Met Leu Pro Ile Asp Glu Xaa Phe Ala Arg Gln Leu Asp Leu Met Gln 85 90 95 Val Gln Gly Leu Met 100 < 210 > 28 < 211 > 37 < 212 > PRT < 213 > Artificial Sequence < 220 > < 223 > Aov Int - C < 400 > 28 Met Val Lys Ile Thr Ala Arg Lys Phe Val Gly Arg Glu Asn Val Tyr 1 5 10 15 Asp Ile Gly Val Glu His His His Asn Phe Ala Ile Lys Asn Gly Leu 20 25 30 Ile Ala Ser Asn Cys 35 < 210 > 29 < 211 > 101 < 212 > PRT < 213 > Artificial Sequence < 220 > < 223 > Ter - 3 Int - N < 400 > 29 Cys Leu Thr Tyr Glu Thr Glu Ile Met Thr Val Glu Tyr Gly Pro Leu 1 5 10 15 Pro Ile Gly Lys Ile Val Glu Tyr Arg Ile Glu Cys Thr Val Tyr Thr 20 25 30 Val Asp Lys Asn Cys Tyr Ile Tyr Thr Gln Pro Ile Ala Gln Trp His 35 40 45 Asn Arg Gly Met Gln Glu Val Tyr Glu Tyr Ser Leu Glu Asp Gly Thr 50 55 60 Val Ile Arg Ala Thr Pro Glu His Lys Phe Met Thr Glu Asp Gly Gln 65 70 75 80 Met Leu Pro Ile Asp Glu Ile Phe Glu Arg Asn Leu Asp Leu Lys Cys 85 90 95 Leu Gly Thr Leu Glu 100 < 210 > 30 < 211 > 37 < 212 > PRT < 213 > Artificial Sequence < 220 > < 223 > Ter - 3 Int - C < 400 > 30 Met Val Lys Ile Val Ser Arg Lys Leu Ala Lys Thr Glu Asn Val Tyr 1 5 10 15 Asp Ile Gly Val Arg Lys Asp His Asn Phe Val Leu Ala Asn Gly Leu 20 25 30 Ile Ala Ser Asn Cys 35 < 210 > 31 < 211 > 106 < 212 > PRT < 213 > Artificial Sequence < 220 > < 223 > Ssp 7002 Int - N < 400 > 31 Cys Leu Ala Gly Gly Thr Pro Val Val Thr Val Glu Tyr Gly Val Leu 1 5 10 15 Pro Ile Thr Ile Val Glu Gln Glu Leu Leu Cys His Val Tyr Ser Val 20 25 30 Asp Ala Gln Gly Leu Ile Thr Ala Gln Leu Ile Glu Gln Trp His Gln 35 40 45 Arg Gly Asp Arg Leu Leu Tyr Glu Tyr Glu Leu Glu Asn Gly Gln Met 50 55 60 Ile Arg Ala Thr Pro Asp His Arg Phe Leu Thr Thr Thr Gly Glu Leu 65 70 75 80 Leu Pro Ile Asp Glu Ile Phe Thr Gln Asn Leu Asp Leu Ala Ala Trp 85 90 95 Ala Val Pro Asp Ser Leu Pro Arg Thr Ala 100 105 < 210 > 32 < 211 > 37 < 212 > PRT < 213 > Artificial Sequence < 220 > < 223 > Ssp 7002 Int - C < 400 > 32 Met Val Lys Ile Ile Arg Arg Lys Phe Ile Gly His Ala Pro Thr Tyr 1 5 10 15 Asp Ile Gly Leu Ser Gln Asp His Asn Phe Leu Leu Gly Gln Gly Leu 20 25 30 Ile Ala Ala Asn Cys 35 < 210 > 33 < 211 > 117 < 212 > PRT < 213 > Artificial Sequence < 220 > < 223 > Tvu Int - N < 400 > 33 Cys Leu Ser Gly Glu Thr Ala Val Met Thr Val Glu Tyr Gly Ala Ile 1 5 10 15 Pro Ile Arg Arg Leu Val Gln Glu Arg Leu Ile Cys Gln Val Tyr Ser 20 25 30 Leu Asp Pro Gln Gly His Leu Tyr Thr Gln Pro Ile Ala Gln Trp His 35 40 45 Phe Gln Gly Phe Arg Pro Val Tyr Ala Tyr Gln Leu Glu Asp Gly Ser 50 55 60 Thr Ile Cys Ala Thr Pro Asp His Arg Phe Met Thr Thr Ser Gly Gln 65 70 75 80 Met Leu Pro Ile Glu Gln Ile Phe Arg Glu Gly Leu Glu Leu Trp Gln 85 90 95 Val Ala Ile Ala Pro Pro Gly Ala Leu Ala Gln Gly Leu Lys Pro Ala 100 105 110 Val Gln Met Ser Cys 115 < 210 > 34 < 211 > 36 < 212 > PRT < 213 > Artificial Sequence < 220 > < 223 > Tvu Int - C < 400 > 34 Met Lys Ile Val Gly Arg Arg Leu Val Gly Trp Gln Ala Val Tyr Asp 1 5 10 15 Ile Cys Leu Ala Gly Asp His Asn Phe Leu Leu Ala Asn Gly Ala Ile 20 25 30 Ala Ala Asn Cys 35 < 210 > 35 < 211 > 117 < 212 > PRT < 213 > Artificial Sequence < 220 > < 223 > Tel Int - N < 400 > 35 Cys Leu Ser Gly Glu Thr Ala Val Met Thr Val Glu Tyr Gly Ala Val 1 5 10 15 Pro Ile Arg Arg Leu Val Gln Glu Arg Leu Ser Cys His Val Tyr Ser 20 25 30 Leu Asp Gly Gln Gly His Leu Tyr Thr Gln Pro Ile Ala Gln Trp His 35 40 45 Phe Gln Gly Phe Arg Phe Val Tyr Glu Tyr Gln Leu Glu Asp Gly Ser 50 55 60 Thr Ile Cys Ala Thr Pro Asp His Arg Phe Met Thr Thr Arg Gly Gln 65 70 75 80 Met Leu Pro Ile Glu Gln Ile Phe Gln Glu Gly Leu Glu Leu Trp Gln 85 90 95 Val Ala Ile Ala Pro Arg Gln Ala Leu Leu Gln Gly Leu Lys Pro Ala 100 105 110 Val Gln Met Ser Gly 115 < 210 > 36 < 211 > 36 < 212 > PRT < 213 > Artificial Sequence < 220 > < 223 > Tel Int - C < 400 > 36 Met Lys Ile Val Gly Arg Arg Leu Met Gly Trp Gln Ala Val Tyr Asp 1 5 10 15 Ile Gly Leu Ala Ala Asp His Asn Phe Val Leu Ala Asn Gly Ala Ile 20 25 30 Ala Ala Asn Cys 35 < 210 > 37 < 211 > 113 < 212 > PRT < 213 > Artificial Sequence < 220 > < 223 > Sel Int - N < 400 > 37 Cys Leu Ala Ala Asp Thr Glu Val Leu Thr Val Glu Tyr Gly Pro Ile 1 5 10 15 Ala Ile Gly Lys Leu Val Glu Glu Asn Ile Arg Cys Gln Val Tyr Cys 20 25 30 Cys Asn Pro Asp Gly Tyr Ile Tyr Ser Gln Pro Ile Gly Gln Trp His 35 40 45 Gln Arg Gly Glu Gln Glu Val Ile Glu Tyr Glu Leu Ser Asp Gly Arg 50 55 60 Ile Ile Arg Ala Thr Ala Asp His Arg Phe Met Thr Glu Glu Gly Glu 65 70 75 80 Met Leu Ser Leu Asp Glu Ile Phe Glu Arg Ser Leu Glu Leu Lys Gln 85 90 95 Ile Pro Thr Pro Leu Leu Ala Ile Ala Gln Pro Ser Pro Leu Ala Thr 100 105 110 Ala < 210 > 38 < 211 > 37 < 212 > PRT < 213 > Artificial Sequence < 220 > < 223 > Sel Int - C < 400 > 38 Met Val Lys Ile Val Arg Arg Arg Ser Leu Gly Val Gln Pro Val Tyr 1 5 10 15 Asp Leu Gly Val Ala Thr Val His Asn Phe Val Leu Ala Asn Gly Leu 20 25 30 Val Ala Ser Asn Cys 35 < 210 > 39 < 211 > 110 < 212 > PRT < 213 > Artificial Sequence < 220 > < 223 > Aha Int - N < 400 > 39 Cys Leu Ser Tyr Asp Thr Glu Ile Trp Thr Val Glu Tyr Gly Ala Met 1 5 10 15 Pro Ile Gly Lys Ile Val Glu Glu Lys Ile Glu Ser Cys Val Tyr Thr 20 25 30 Val Asp Glu Asn Gly Phe Val Tyr Thr Gln Pro Ile Ala Gln Trp His 35 40 45 Pro Arg Gly Gln Gln Glu Ile Ile Glu Tyr Thr Leu Glu Asp Gly Arg 50 55 60 Lys Ile Arg Ala Thr Lys Asp His Lys Met Met Thr Glu Ser Gly Glu 65 70 75 80 Met Leu Pro Ile Glu Glu Ile Phe Gln Arg Glu Leu Asp Leu Lys Val 85 90 95 Glu Thr Phe His Glu Met Ser Leu Leu Arg Arg Gly Ala Lys 100 105 110 < 210 > 40 < 211 > 37 < 212 > PRT < 213 > Artificial Sequence < 220 > < 223 > Aha Int - C < 400 > 40 Met Val Lys Ile Ile Lys Arg Gln Ser Leu Gly Arg Gln Asn Val Tyr 1 5 10 15 Asp Val Cys Val Glu Thr Asp His Asn Phe Val Leu Ala Asn Gly Cys 20 25 30 Val Ala Ser Asn Cys 35