1 H NMR ( 300 MHz , CDCl 3 ) δ 1 . 22 - 1 . 46 ( m , 5 H ) , 1 . 65 - 1 . 83 ( m , 5 H ) , 1 . 95 - 1 . 99 ( m , 1 H ) , 2 . 18 - 2 . 29 ( m , 1 H ) , 3 . 66 - 3 . 76 ( m , 1 H ) , 3 . 99 - 4 . 07 ( m , 1 H ) 4 . 19 ( s , 3 H ) , 4 . 61 ( d , 2 H , J = 5 . 7 Hz ) , 5 . 29 ( d , 1 H , J = 10 . 5 Hz ) , 5 . 43 ( d , 1 H , J = 18 . 9 Hz ) , 6 . 08 - 6 . 19 ( m , 1 H ) , 6 . 20 ( d , 1 H , J = 12 . 3 Hz ) , 6 . 72 ( d , 1 H , J = 2 . 4 Hz ) , 7 . 07 ( s , 1 H , J = 12 . 3 Hz ) , 7 . 35 ( s , 1 H ) , 7 . 61 ( d , 1 H , J = 2 . 4 Hz ) , 8 . 04 ( br s , 1 H )