1 H NMR ( CDCl 3 ) δ 8 . 58 ( 1 H , ddd , J = 4 . 9 , 1 . 8 , 1 . 2 Hz ) , 7 . 52 ( 1 H , br d , J = 4 . 9 Hz ) , 7 . 48 ( 1 H , ddd , J = 7 . 9 , 1 . 8 , 1 . 2 Hz ) , 7 . 23 ( 1 H , dd , J = 7 . 9 , 4 . 9 Hz ) , 7 . 17 ( 1 H , dd , J = 7 . 9 , 2 . 4 Hz ) , 7 . 09 ( 1 H , dd , J = 8 . 6 , 2 . 4 Hz ) , 4 . 79 - 4 . 73 ( 4 H , m ) , 4 . 65 ( 1 H , dd , J = 14 . 7 , 6 . 1 Hz ) , 3 . 82 ( 1 H , br ) , 3 . 67 ( 1 H , br ) , 2 . 61 ( 1 H , m ) , 2 . 37 - 2 . 21 ( 2 H , m ) , 2 . 11 ( 1 H , m ) .