Theoretically its possible but would involve a bug or hidden mechanic that is not working as intended like the season the monk spec was discovered midseason by a console user thanks to snapshotting and dragging the snapshot through the instance . If you are dreaming of slapping on the LON set on a wizard and tinkering with runes and gear , no , you will not discover some magic new meta . Everything has been tried and the simple truth is 95 % of the runes in this game are complete unusable garbage . The other problem is how Blizzard designs the gameplay . They take the 1 skill THEY want you to use and then design sets and pieces to support that skill . This further exaggerates how bad other options are in live and funnels people into the working cookie cutter .