화합물 137 - E 2 LC / MS ESI 463 . 2 ( M + H ) +. 1 H NMR ( 500 MHz , MeOD ) δ 7 . 59 ? 7 . 52 ( m , 2 H ) , 7 . 46 ? 7 . 38 ( m , 3 H ) , 7 . 13 ( d , J = 7 . 1 Hz , 1 H ) , 6 . 33 ( d , J = 7 . 3 Hz , 1 H ) , 4 . 59 ( s , 1 H ) , 4 . 46 ( d , J = 12 . 3 Hz , 1 H ) , 3 . 92 ( d , J = 13 . 4 Hz , 1 H ) , 3 . 63 ( s , 2 H ) , 3 . 39 ? 3 . 35 ( m , 3 H ) , 3 . 16 ( br , 1 H ) , 3 . 10 ? 3 . 00 ( m , 2 H ) , 2 . 69 ( t , J = 6 . 3 Hz , 2 H ) , 2 . 61 ( t , J = 13 . 3 Hz , 1 H ) , 2 . 44 ( d , J = 7 . 1 Hz , 2 H ) , 2 . 28 ( d , J = 18 . 9 Hz , 1 H ) , 2 . 11 ? 2 . 00 ( m , 1 H ) , 1 . 92 ( s , 1 H ) , 1 . 89 ? 1 . 84 ( m , 2 H ) , 1 . 73 ? 1 . 65 ( m , 2 H ) , 1 . 20 ? 1 . 04 ( m , 2 H ) . 키 랄 SFC A ( 45 % MeOH ) : ee 100 %, Rt = 3 . 43 분