Sorry , but a noob question . Do you mean use tbol from week 4 to week 8 of the 15 weeks cycle , or use it for 48 weeks starting from week 1 ? And is the dosage 50 mg every day ? <| sep |> He ' s down , he had firm control until his knee hit imo . <| sep |> A personal suggestion I started with ME 3 it was free on Plus once . Then I went back later and played 1 and 2 in order and set it up as a prequel . For me , ME 3 was one of the best games ever and I loved the end . However , those who had played through 1 and 2 before playing 3 , were very disappointed with the ending at least until it was fixed . And by playing 3 first , I got to know several characters history afterwards instead of beforehand . It ' s all down to how much fantasy you have , and if you ' re good at accepting that things have happened but you don ' t know exactly how a bit like Star Wars . Just my two cents