That ' s interesting . Something weird has been going on with my vyvanse . I worked up to 70 mg which I took for about 3 years , then went down to 60 mg and now 30 mg isn ' t enough but 50 mg is giving me too much anxiety . I ' m gonna try 40 mg soon . <| sep |> Proteins don ' t replicate so prions aren ' t replicating per say , just aggregating . When more of the prion protein is synthesized it ' s much more likely to form an aggregate if there is already some seed to template off . This is why they can affect people even after the carrier has died , like you mention below . If you eat brain , you ' re increasing the odds of contracting some form of prion disease , because brains often contain these seed aggregates that accelerate plaque formation .