SEQUENCE LISTING < 110 > Monash University Mackay , Charles R Robert , Remy M < 120 > CXCR 2 Antibodies and Uses Thereof < 130 > 048517 - 532001 WO < 150 > AU 2017900656 < 151 > 2017 - 02 - 27 < 160 > 62 < 170 > PatentIn version 3 . 5 < 210 > 1 < 211 > 11 < 212 > PRT < 213 > Artificial sequence < 220 > < 223 > Synthetic Polypeptide < 400 > 1 Gln Ser Leu Val His Ser Asn Gly Asn Thr Tyr 1 5 10 < 210 > 2 < 211 > 3 < 212 > PRT < 213 > Artificial sequence < 220 > < 223 > Synthetic Polypeptide < 400 > 2 Lys Val Ser 1 < 210 > 3 < 211 > 9 < 212 > PRT < 213 > Artificial sequence < 220 > < 223 > Synthetic Polypeptide < 400 > 3 Ser Gln Gly Thr His Val Pro Tyr Thr 1 5 < 210 > 4 < 211 > 8 < 212 > PRT < 213 > Artificial sequence < 220 > < 223 > Synthetic Polypeptide < 400 > 4 Gly Tyr Ala Phe Ser Asn Ser Trp 1 5 < 210 > 5 < 211 > 8 < 212 > PRT < 213 > Artificial sequence < 220 > < 223 > Synthetic Polypeptide < 400 > 5 Ile Tyr Pro Gly Asp Gly Asn Ile 1 5 < 210 > 6 < 211 > 11 < 212 > PRT < 213 > Artificial sequence < 220 > < 223 > Synthetic Polypeptide < 400 > 6 Ala Arg Ser Phe Leu Tyr Val Asp Phe Asp Tyr 1 5 10 < 210 > 7 < 211 > 113 < 212 > PRT < 213 > Artificial sequence < 220 > < 223 > Synthetic Polypeptide < 400 > 7 Val Ile Val Met Thr Gln Thr Pro Leu Ser Leu Pro Val Ser Leu Gly 1 5 10 15 Asp Gln Ala Ser Ile Ser Cys Arg Ser Ser Gln Ser Leu Val His Ser 20 25 30 Asn Gly Asn Thr Tyr Leu Gln Trp Tyr Leu Gln Lys Pro Gly Gln Ser 35 40 45 Pro Lys Leu Leu Ile Tyr Lys Val Ser Asn Arg Phe Ser Gly Val Pro 50 55 60 Asp Arg Phe Ser Gly Ser Gly Ser Gly Thr Asp Phe Thr Leu Lys Ile 65 70 75 80 Ser Arg Val Glu Ala Glu Asp Leu Gly Val Tyr Phe Cys Ser Gln Gly 85 90 95 Thr His Val Pro Tyr Thr Phe Gly Gly Gly Thr Lys Leu Glu Ile Lys 100 105 110 Arg < 210 > 8 < 211 > 118 < 212 > PRT < 213 > Artificial sequence < 220 > < 223 > Synthetic Polypeptide < 400 > 8 Gln Val Gln Leu Gln Gln Ser Gly Pro Glu Leu Val Lys Pro Gly Ala 1 5 10 15 Ser Val Lys Ile Ser Cys Lys Ala Ser Gly Tyr Ala Phe Ser Asn Ser 20 25 30 Trp Met Asn Trp Val Lys Gln Arg Pro Gly Lys Gly Leu Glu Trp Ile 35 40 45 Gly Arg Ile Tyr Pro Gly Asp Gly Asn Ile Asn Tyr Tyr Gly Lys Phe 50 55 60 Lys Asp Lys Ala Thr Leu Thr Ala Asp Lys Ser Ser Asn Thr Ala Tyr 65 70 75 80 Met Gln Leu Ser Ser Leu Thr Ser Glu Asp Ser Ala Val Tyr Phe Cys 85 90 95 Ala Arg Ser Phe Leu Tyr Val Asp Phe Asp Tyr Trp Gly Gln Gly Thr 100 105 110 Thr Leu Thr Val Ser Ser 115 < 210 > 9 < 211 > 339 < 212 > DNA < 213 > Artificial sequence < 220 > < 223 > Synthetic Polynucleotide < 400 > 9 gttattgtga tgacccaaac tccactctcc ctgcctgtca gtcttggaga tcaagcctcc 60 atctcttgca gatctagtca gagccttgta cacagtaatg gaaacaccta tttacaatgg 120 tatctgcaga agccaggcca gtctccaaag ctcctgatct acaaagtttc caaccgattt 180 tctggggtcc cagacaggtt cagtggcagt ggatcaggga cagatttcac actcaagatc 240 agcagagtgg aggctgagga tctgggagtt tatttctgct ctcaaggtac acatgttccg 300 tacacgttcg gaggggggac caagctggaa ataaaacgg 339 < 210 > 10 < 211 > 354 < 212 > DNA < 213 > Artificial sequence < 220 > < 223 > Synthetic Polynucleotide < 400 > 10 caggttcagc tgcagcagtc tggacctgag ctggtgaagc ctggggcctc agtgaagatt 60 tcctgcaagg cttctggcta cgcattcagt aactcctgga tgaactgggt gaagcagagg 120 cctggaaagg gtcttgagtg gattggacgg atttatcctg gagatggaaa tattaactac 180 tatgggaagt tcaaggacaa ggccacactg actgcagaca aatcctccaa cacagcctac 240 atgcaactca gcagcctgac atctgaggac tctgcggtct acttctgtgc aaggagtttt 300 ctctacgtgg actttgacta ctggggccaa ggcaccactc tcacagtctc ctca 354 < 210 > 11 < 211 > 11 < 212 > PRT < 213 > Artificial sequence < 220 > < 223 > Synthetic Polypeptide < 400 > 11 Gln Thr Leu Val His Ser Asn Gly Asn Thr Tyr 1 5 10 < 210 > 12 < 211 > 3 < 212 > PRT < 213 > Artificial sequence < 220 > < 223 > Synthetic Polypeptide < 400 > 12 Lys Val Ser 1 < 210 > 13 < 211 > 9 < 212 > PRT < 213 > Artificial sequence < 220 > < 223 > Synthetic Polypeptide < 400 > 13 Ser Gln Gly Thr His Val Pro Tyr Thr 1 5 < 210 > 14 < 211 > 8 < 212 > PRT < 213 > Artificial sequence < 220 > < 223 > Synthetic Polypeptide < 400 > 14 Gly Tyr Ala Phe Ser Asn Ser Trp 1 5 < 210 > 15 < 211 > 8 < 212 > PRT < 213 > Artificial sequence < 220 > < 223 > Synthetic Polypeptide < 400 > 15 Ile Tyr Pro Gly Asp Gly Asn Ile 1 5 < 210 > 16 < 211 > 11 < 212 > PRT < 213 > Artificial sequence < 220 > < 223 > Synthetic Polypeptide < 400 > 16 Ala Arg Ser Phe Leu Tyr Val Asp Phe Asp Tyr 1 5 10 < 210 > 17 < 211 > 113 < 212 > PRT < 213 > Artificial sequence < 220 > < 223 > Synthetic Polypeptide < 400 > 17 Asp Val Val Met Thr Gln Ala Pro Leu Ser Leu Pro Val Ser Leu Gly 1 5 10 15 Asp Gln Ala Ser Ile Ser Cys Arg Ser Ser Gln Thr Leu Val His Ser 20 25 30 Asn Gly Asn Thr Tyr Leu Gln Trp Tyr Leu Gln Lys Pro Gly Gln Ser 35 40 45 Pro Lys Leu Leu Ile Tyr Lys Val Ser Asn Arg Phe Ser Gly Val Pro 50 55 60 Asp Arg Phe Ser Gly Ser Gly Ser Gly Thr Asp Phe Thr Leu Lys Ile 65 70 75 80 Ser Arg Val Glu Ala Glu Asp Leu Gly Val Tyr Phe Cys Ser Gln Gly 85 90 95 Thr His Val Pro Tyr Thr Phe Gly Gly Gly Thr Lys Leu Glu Ile Lys 100 105 110 Arg < 210 > 18 < 211 > 118 < 212 > PRT < 213 > Artificial sequence < 220 > < 223 > Synthetic Polypeptide < 400 > 18 Gln Val Gln Leu Gln Gln Ser Gly Pro Glu Leu Val Lys Pro Gly Ala 1 5 10 15 Ser Val Lys Ile Ser Cys Lys Ala Ser Gly Tyr Ala Phe Ser Asn Ser 20 25 30 Trp Met Asn Trp Val Lys Gln Arg Pro Gly Lys Gly Leu Glu Trp Ile 35 40 45 Gly Arg Ile Tyr Pro Gly Asp Gly Asn Ile Asn Tyr Tyr Gly Lys Phe 50 55 60 Lys Asp Lys Ala Thr Leu Thr Ala Asp Lys Ser Ser Asn Thr Ala Tyr 65 70 75 80 Met Gln Leu Ser Ser Leu Thr Ser Glu Asp Ser Ala Val Tyr Phe Cys 85 90 95 Ala Arg Ser Phe Leu Tyr Val Asp Phe Asp Tyr Trp Gly Gln Gly Thr 100 105 110 Thr Leu Thr Val Ser Ser 115 < 210 > 19 < 211 > 339 < 212 > DNA < 213 > Artificial sequence < 220 > < 223 > Synthetic Polynucleotide < 400 > 19 gatgttgtga tgacccaagc tccactctcc ctgcctgtca gtcttggaga tcaagcctcc 60 atctcttgca ggtctagtca gacccttgta cacagtaatg gaaacaccta tttacaatgg 120 tatctgcaga agccaggcca gtctccaaag ctcctgatct acaaagtttc caaccgattt 180 tctggggtcc cagacaggtt cagtggcagt ggatcaggga cagatttcac actcaagatc 240 agcagagtgg aggctgagga tctgggagtt tatttctgct ctcaaggtac acatgttccg 300 tacacgttcg gaggggggac caagctggaa ataaaacgg 339 < 210 > 20 < 211 > 354 < 212 > DNA < 213 > Artificial sequence < 220 > < 223 > Synthetic Polynucleotide < 400 > 20 caggttcagc tgcagcagtc tggacctgag ctggtgaagc ctggggcctc agtgaagatt 60 tcctgcaagg cttctggcta cgcattcagt aactcctgga tgaactgggt gaagcagagg 120 cctggaaagg gtcttgagtg gattggacgg atttatcctg gagatggaaa tattaactac 180 tatgggaagt tcaaggacaa ggccacactg actgcagaca aatcctccaa cacagcctac 240 atgcaactca gcagcctgac atctgaggac tctgcggtct acttctgtgc aaggagtttt 300 ctctacgtgg actttgacta ctggggccaa ggcaccactc tcacagtctc ctca 354 < 210 > 21 < 211 > 11 < 212 > PRT < 213 > Artificial sequence < 220 > < 223 > Synthetic Polypeptide < 400 > 21 Gln Ser Leu Val His Ser Asn Gly Asn Thr Tyr 1 5 10 < 210 > 22 < 211 > 3 < 212 > PRT < 213 > Artificial sequence < 220 > < 223 > Synthetic Polypeptide < 400 > 22 Lys Leu Ser 1 < 210 > 23 < 211 > 9 < 212 > PRT < 213 > Artificial sequence < 220 > < 223 > Synthetic Polypeptide < 400 > 23 Ser Gln Ser Thr His Val Pro Tyr Thr 1 5 < 210 > 24 < 211 > 8 < 212 > PRT < 213 > Artificial sequence < 220 > < 223 > Synthetic Polypeptide < 400 > 24 Gly Tyr Ala Phe Ser Asn Ser Trp 1 5 < 210 > 25 < 211 > 8 < 212 > PRT < 213 > Artificial sequence < 220 > < 223 > Synthetic Polypeptide < 400 > 25 Ile Tyr Pro Gly Asp Gly Asn Ile 1 5 < 210 > 26 < 211 > 11 < 212 > PRT < 213 > Artificial sequence < 220 > < 223 > Synthetic Polypeptide < 400 > 26 Ala Arg Ser Phe Leu Tyr Val Tyr Phe Asp Tyr 1 5 10 < 210 > 27 < 211 > 113 < 212 > PRT < 213 > Artificial sequence < 220 > < 223 > Synthetic Polypeptide < 400 > 27 Asp Ala Val Met Thr Gln Thr Pro Leu Ser Leu Pro Val Ser Leu Gly 1 5 10 15 Asp Gln Ala Ser Ile Ser Cys Arg Ser Ser Gln Ser Leu Val His Ser 20 25 30 Asn Gly Asn Thr Tyr Leu Gln Trp Tyr Leu Gln Lys Pro Gly Gln Ser 35 40 45 Pro Lys Leu Leu Ile Tyr Lys Leu Ser Asn Arg Phe Ser Gly Val Pro 50 55 60 Asp Arg Phe Ser Gly Ser Gly Ala Gly Thr Asp Phe Thr Leu Lys Ile 65 70 75 80 Ser Arg Val Glu Ala Glu Asp Leu Gly Val Tyr Phe Cys Ser Gln Ser 85 90 95 Thr His Val Pro Tyr Thr Phe Gly Gly Gly Thr Lys Leu Glu Ile Lys 100 105 110 Arg < 210 > 28 < 211 > 118 < 212 > PRT < 213 > Artificial sequence < 220 > < 223 > Synthetic Polypeptide < 400 > 28 Gln Val Gln Leu Gln Gln Ser Gly Pro Glu Leu Val Lys Pro Gly Ala 1 5 10 15 Ser Val Lys Ile Ser Cys Lys Ala Ser Gly Tyr Ala Phe Ser Asn Ser 20 25 30 Trp Met Asn Trp Val Lys Gln Arg Pro Gly Lys Gly Leu Glu Trp Ile 35 40 45 Gly Arg Ile Tyr Pro Gly Asp Gly Asn Ile Asn Tyr Tyr Gly Lys Phe 50 55 60 Lys Asp Lys Ala Thr Leu Thr Ala Asp Lys Ser Ser Asn Thr Ala Tyr 65 70 75 80 Met Gln Leu Ser Ser Leu Thr Ser Glu Asp Ser Ala Val Tyr Phe Cys 85 90 95 Ala Arg Ser Phe Leu Tyr Val Tyr Phe Asp Tyr Trp Gly Gln Gly Thr 100 105 110 Thr Leu Thr Val Ser Ser 115 < 210 > 29 < 211 > 339 < 212 > DNA < 213 > Artificial sequence < 220 > < 223 > Synthetic Polynucleotide < 400 > 29 gatgctgtga tgacccaaac tccactctcc ctgcctgtca gtcttggaga tcaagcctcc 60 atctcttgca gatctagtca gagccttgta cacagtaatg gaaacaccta tttacaatgg 120 tatctgcaga agccaggcca gtctccaaag ctcctgatct acaaactttc caaccgattt 180 tctggggtcc cagacaggtt cagtggcagt ggagcaggga cagatttcac actcaagatc 240 agcagagtgg aggctgagga tctgggagtt tatttctgct ctcaaagtac acatgttccg 300 tacacgttcg gaggggggac caagctggaa ataaaacgg 339 < 210 > 30 < 211 > 354 < 212 > DNA < 213 > Artificial sequence < 220 > < 223 > Synthetic Polynucleotide < 400 > 30 caggttcagc tgcagcagtc tggacctgaa ctggtgaagc ctggggcctc agtgaagatt 60 tcctgtaagg cttctggcta cgcattcagt aactcctgga tgaactgggt gaagcagagg 120 cctggaaagg gtcttgagtg gattggacgg atttatcctg gagatggaaa tattaactac 180 tatgggaagt tcaaggacaa ggccacactg actgcagaca aatcctccaa cacagcctac 240 atgcaactca gcagcctgac atctgaggac tctgcggtct acttctgtgc aaggagtttt 300 ctctacgtgt actttgacta ctggggccaa ggcaccactc tcacagtctc ctca 354 < 210 > 31 < 211 > 113 < 212 > PRT < 213 > Artificial sequence < 220 > < 223 > Synthetic Polypeptide < 400 > 31 Asp Ile Val Met Thr Gln Ser Pro Leu Ser Leu Pro Val Thr Pro Gly 1 5 10 15 Glu Pro Ala Ser Ile Ser Cys Arg Ser Ser Gln Ser Leu Val His Ser 20 25 30 Asn Gly Asn Thr Tyr Leu Gln Trp Tyr Leu Gln Lys Pro Gly Gln Ser 35 40 45 Pro Gln Leu Leu Ile Tyr Lys Val Ser Asn Arg Phe Ser Gly Val Pro 50 55 60 Asp Arg Phe Ser Gly Ser Gly Ser Gly Thr Asp Phe Thr Leu Lys Ile 65 70 75 80 Ser Arg Val Glu Ala Glu Asp Val Gly Val Tyr Phe Cys Ser Gln Gly 85 90 95 Thr His Val Pro Tyr Thr Phe Gly Gln Gly Thr Lys Leu Glu Ile Lys 100 105 110 Arg < 210 > 32 < 211 > 118 < 212 > PRT < 213 > Artificial sequence < 220 > < 223 > Synthetic Polypeptide < 400 > 32 Gln Val Gln Leu Val Gln Ser Gly Ala Glu Val Lys Lys Pro Gly Ala 1 5 10 15 Ser Val Lys Val Ser Cys Lys Ala Ser Gly Tyr Ala Phe Ser Asn Ser 20 25 30 Trp Met Asn Trp Val Arg Gln Ala Pro Gly Gln Arg Leu Glu Trp Ile 35 40 45 Gly Arg Ile Tyr Pro Gly Asp Gly Asn Ile Asn Tyr Tyr Gly Lys Phe 50 55 60 Lys Asp Lys Ala Thr Leu Thr Ala Asp Lys Ser Ala Asn Thr Ala Tyr 65 70 75 80 Met Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala Val Tyr Phe Cys 85 90 95 Ala Arg Ser Phe Leu Tyr Val Asp Phe Asp Tyr Trp Gly Gln Gly Thr 100 105 110 Thr Leu Thr Val Ser Ser 115 < 210 > 33 < 211 > 26 < 212 > PRT < 213 > Artificial sequence < 220 > < 223 > Synthetic Polypeptide < 400 > 33 Val Ile Val Met Thr Gln Thr Pro Leu Ser Leu Pro Val Ser Leu Gly 1 5 10 15 Asp Gln Ala Ser Ile Ser Cys Arg Ser Ser 20 25 < 210 > 34 < 211 > 26 < 212 > PRT < 213 > Artificial sequence < 220 > < 223 > Synthetic Polypeptide < 400 > 34 Asp Val Val Met Thr Gln Ala Pro Leu Ser Leu Pro Val Ser Leu Gly 1 5 10 15 Asp Gln Ala Ser Ile Ser Cys Arg Ser Ser 20 25 < 210 > 35 < 211 > 26 < 212 > PRT < 213 > Artificial sequence < 220 > < 223 > Synthetic Polypeptide < 400 > 35 Asp Ala Val Met Thr Gln Thr Pro Leu Ser Leu Pro Val Ser Leu Gly 1 5 10 15 Asp Gln Ala Ser Ile Ser Cys Arg Ser Ser 20 25 < 210 > 36 < 211 > 17 < 212 > PRT < 213 > Artificial sequence < 220 > < 223 > Synthetic Polypeptide < 400 > 36 Leu Gln Trp Tyr Leu Gln Lys Pro Gly Gln Ser Pro Lys Leu Leu Ile 1 5 10 15 Tyr < 210 > 37 < 211 > 36 < 212 > PRT < 213 > Artificial sequence < 220 > < 223 > Synthetic Polypeptide < 400 > 37 Asn Arg Phe Ser Gly Val Pro Asp Arg Phe Ser Gly Ser Gly Ser Gly 1 5 10 15 Thr Asp Phe Thr Leu Lys Ile Ser Arg Val Glu Ala Glu Asp Leu Gly 20 25 30 Val Tyr Phe Cys 35 < 210 > 38 < 211 > 36 < 212 > PRT < 213 > Artificial sequence < 220 > < 223 > Synthetic Polypeptide < 400 > 38 Asn Arg Phe Ser Gly Val Pro Asp Arg Phe Ser Gly Ser Gly Ala Gly 1 5 10 15 Thr Asp Phe Thr Leu Lys Ile Ser Arg Val Glu Ala Glu Asp Leu Gly 20 25 30 Val Tyr Phe Cys 35 < 210 > 39 < 211 > 11 < 212 > PRT < 213 > Artificial sequence < 220 > < 223 > Synthetic Polypeptide < 400 > 39 Phe Gly Gly Gly Thr Lys Leu Glu Ile Lys Arg 1 5 10 < 210 > 40 < 211 > 25 < 212 > PRT < 213 > Artificial sequence < 220 > < 223 > Synthetic Polypeptide < 400 > 40 Gln Val Gln Leu Gln Gln Ser Gly Pro Glu Leu Val Lys Pro Gly Ala 1 5 10 15 Ser Val Lys Ile Ser Cys Lys Ala Ser 20 25 < 210 > 41 < 211 > 17 < 212 > PRT < 213 > Artificial sequence < 220 > < 223 > Synthetic Polypeptide < 400 > 41 Met Asn Trp Val Lys Gln Arg Pro Gly Lys Gly Leu Glu Trp Ile Gly 1 5 10 15 Arg < 210 > 42 < 211 > 38 < 212 > PRT < 213 > Artificial sequence < 220 > < 223 > Synthetic Polypeptide < 400 > 42 Asn Tyr Tyr Gly Lys Phe Lys Asp Lys Ala Thr Leu Thr Ala Asp Lys 1 5 10 15 Ser Ser Asn Thr Ala Tyr Met Gln Leu Ser Ser Leu Thr Ser Glu Asp 20 25 30 Ser Ala Val Tyr Phe Cys 35 < 210 > 43 < 211 > 11 < 212 > PRT < 213 > Artificial sequence < 220 > < 223 > Synthetic Polypeptide < 400 > 43 Trp Gly Gln Gly Thr Thr Leu Thr Val Ser Ser 1 5 10 < 210 > 44 < 211 > 26 < 212 > PRT < 213 > Artificial sequence < 220 > < 223 > Synthetic Polypeptide < 400 > 44 Asp Ile Val Met Thr Gln Ser Pro Leu Ser Leu Pro Val Thr Pro Gly 1 5 10 15 Glu Pro Ala Ser Ile Ser Cys Arg Ser Ser 20 25 < 210 > 45 < 211 > 17 < 212 > PRT < 213 > Artificial sequence < 220 > < 223 > Synthetic Polypeptide < 400 > 45 Leu Gln Trp Tyr Leu Gln Lys Pro Gly Gln Ser Pro Gln Leu Leu Ile 1 5 10 15 Tyr < 210 > 46 < 211 > 36 < 212 > PRT < 213 > Artificial sequence < 220 > < 223 > Synthetic Polypeptide < 400 > 46 Asn Arg Phe Ser Gly Val Pro Asp Arg Phe Ser Gly Ser Gly Ser Gly 1 5 10 15 Thr Asp Phe Thr Leu Lys Ile Ser Arg Val Glu Ala Glu Asp Val Gly 20 25 30 Val Tyr Phe Cys 35 < 210 > 47 < 211 > 11 < 212 > PRT < 213 > Artificial sequence < 220 > < 223 > Synthetic Polypeptide < 400 > 47 Phe Gly Gln Gly Thr Lys Leu Glu Ile Lys Arg 1 5 10 < 210 > 48 < 211 > 25 < 212 > PRT < 213 > Artificial sequence < 220 > < 223 > Synthetic Polypeptide < 400 > 48 Gln Val Gln Leu Val Gln Ser Gly Ala Glu Val Lys Lys Pro Gly Ala 1 5 10 15 Ser Val Lys Val Ser Cys Lys Ala Ser 20 25 < 210 > 49 < 211 > 17 < 212 > PRT < 213 > Artificial sequence < 220 > < 223 > Synthetic Polypeptide < 400 > 49 Met Asn Trp Val Arg Gln Ala Pro Gly Gln Arg Leu Glu Trp Ile Gly 1 5 10 15 Arg < 210 > 50 < 211 > 38 < 212 > PRT < 213 > Artificial sequence < 220 > < 223 > Synthetic Polypeptide < 400 > 50 Asn Tyr Tyr Gly Lys Phe Lys Asp Lys Ala Thr Leu Thr Ala Asp Lys 1 5 10 15 Ser Ala Asn Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu Asp 20 25 30 Thr Ala Val Tyr Phe Cys 35 < 210 > 51 < 211 > 11 < 212 > PRT < 213 > Artificial sequence < 220 > < 223 > Synthetic Polypeptide < 400 > 51 Trp Gly Gln Gly Thr Thr Leu Thr Val Ser Ser 1 5 10 < 210 > 52 < 211 > 360 < 212 > PRT < 213 > Artificial sequence < 220 > < 223 > Synthetic Polypeptide < 400 > 52 Met Glu Asp Phe Asn Met Glu Ser Asp Ser Phe Glu Asp Phe Trp Lys 1 5 10 15 Gly Glu Asp Leu Ser Asn Tyr Ser Tyr Ser Ser Thr Leu Pro Pro Phe 20 25 30 Leu Leu Asp Ala Ala Pro Cys Glu Pro Glu Ser Leu Glu Ile Asn Lys 35 40 45 Tyr Phe Val Val Ile Ile Tyr Ala Leu Val Phe Leu Leu Ser Leu Leu 50 55 60 Gly Asn Ser Leu Val Met Leu Val Ile Leu Tyr Ser Arg Val Gly Arg 65 70 75 80 Ser Val Thr Asp Val Tyr Leu Leu Asn Leu Ala Leu Ala Asp Leu Leu 85 90 95 Phe Ala Leu Thr Leu Pro Ile Trp Ala Ala Ser Lys Val Asn Gly Trp 100 105 110 Ile Phe Gly Thr Phe Leu Cys Lys Val Val Ser Leu Leu Lys Glu Val 115 120 125 Asn Phe Tyr Ser Gly Ile Leu Leu Leu Ala Cys Ile Ser Val Asp Arg 130 135 140 Tyr Leu Ala Ile Val His Ala Thr Arg Thr Leu Thr Gln Lys Arg Tyr 145 150 155 160 Leu Val Lys Phe Ile Cys Leu Ser Ile Trp Gly Leu Ser Leu Leu Leu 165 170 175 Ala Leu Pro Val Leu Leu Phe Arg Arg Thr Val Tyr Ser Ser Asn Val 180 185 190 Ser Pro Ala Cys Tyr Glu Asp Met Gly Asn Asn Thr Ala Asn Trp Arg 195 200 205 Met Leu Leu Arg Ile Leu Pro Gln Ser Phe Gly Phe Ile Val Pro Leu 210 215 220 Leu Ile Met Leu Phe Cys Tyr Gly Phe Thr Leu Arg Thr Leu Phe Lys 225 230 235 240 Ala His Met Gly Gln Lys His Arg Ala Met Arg Val Ile Phe Ala Val 245 250 255 Val Leu Ile Phe Leu Leu Cys Trp Leu Pro Tyr Asn Leu Val Leu Leu 260 265 270 Ala Asp Thr Leu Met Arg Thr Gln Val Ile Gln Glu Thr Cys Glu Arg 275 280 285 Arg Asn His Ile Asp Arg Ala Leu Asp Ala Thr Glu Ile Leu Gly Ile 290 295 300 Leu His Ser Cys Leu Asn Pro Leu Ile Tyr Ala Phe Ile Gly Gln Lys 305 310 315 320 Phe Arg His Gly Leu Leu Lys Ile Leu Ala Ile His Gly Leu Ile Ser 325 330 335 Lys Asp Ser Leu Pro Lys Asp Ser Arg Pro Ser Phe Val Gly Ser Ser 340 345 350 Ser Gly His Thr Ser Thr Thr Leu 355 360 < 210 > 53 < 211 > 21 < 212 > PRT < 213 > Artificial sequence < 220 > < 223 > Synthetic Polypeptide < 400 > 53 Met Glu Asp Phe Asn Met Glu Ser Asp Ser Phe Glu Asp Phe Trp Lys 1 5 10 15 Gly Glu Asp Leu Ser 20 < 210 > 54 < 211 > 29 < 212 > PRT < 213 > Artificial sequence < 220 > < 223 > Synthetic Polypeptide < 400 > 54 Leu Ser Asn Tyr Ser Tyr Ser Ser Thr Leu Pro Pro Phe Leu Leu Asp 1 5 10 15 Ala Ala Pro Cys Glu Pro Glu Ser Leu Glu Ile Asn Lys 20 25 < 210 > 55 < 211 > 22 < 212 > PRT < 213 > Artificial sequence < 220 > < 223 > Synthetic Polypeptide < 400 > 55 Ser Phe Glu Asp Phe Trp Lys Gly Glu Asp Leu Ser Asn Tyr Ser Tyr 1 5 10 15 Ser Ser Thr Leu Pro Pro 20 < 210 > 56 < 211 > 117 < 212 > PRT < 213 > Artificial sequence < 220 > < 223 > Synthetic Polypeptide < 400 > 56 Gln Val Gln Leu Val Gln Ser Gly Ala Glu Val Lys Lys Pro Gly Ala 1 5 10 15 Ser Val Lys Val Ser Cys Lys Ala Ser Gly Tyr Thr Phe Ser Asn Ser 20 25 30 Trp Met Asn Trp Val Arg Gln Ala Pro Gly Gln Arg Leu Glu Trp Ile 35 40 45 Gly Arg Ile Tyr Pro Gly Asp Gly Asn Ile Asn Tyr Tyr Gly Lys Phe 50 55 60 Lys Asp Lys Ala Thr Leu Thr Ala Asp Lys Ser Ala Asn Thr Ala Tyr 65 70 75 80 Met Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala Val Tyr Phe Cys 85 90 95 Ala Arg Ser Phe Leu Tyr Val Asp Phe Asp Tyr Trp Gly Gln Gly Thr 100 105 110 Thr Leu Thr Val Ser 115 < 210 > 57 < 211 > 113 < 212 > PRT < 213 > Artificial sequence < 220 > < 223 > Synthetic Polypeptide < 400 > 57 Asp Ile Val Met Thr Gln Ser Pro Leu Ser Leu Pro Val Thr Pro Gly 1 5 10 15 Glu Pro Ala Ser Ile Ser Cys Arg Ser Ser Gln Ser Leu Val His Ser 20 25 30 Asn Gly Asn Thr Tyr Leu Gln Trp Tyr Leu Gln Lys Pro Gly Glu Ser 35 40 45 Pro Gln Leu Leu Ile Tyr Lys Val Ser Asn Arg Phe Ser Gly Val Pro 50 55 60 Asp Arg Phe Ser Gly Ser Gly Ser Gly Thr Asp Phe Thr Leu Lys Ile 65 70 75 80 Ser Arg Val Glu Ala Glu Asp Val Gly Val Tyr Phe Cys Ser Gln Gly 85 90 95 Thr His Val Pro Tyr Thr Phe Gly Gln Gly Thr Lys Leu Glu Ile Lys 100 105 110 Arg < 210 > 58 < 211 > 8 < 212 > PRT < 213 > Artificial sequence < 220 > < 223 > Synthetic Polypeptide < 400 > 58 Gly Tyr Thr Phe Ser Asn Ser Trp 1 5 < 210 > 59 < 211 > 17 < 212 > PRT < 213 > Artificial sequence < 220 > < 223 > Synthetic Polypeptide < 400 > 59 Leu Gln Trp Tyr Leu Gln Lys Pro Gly Glu Ser Pro Gln Leu Leu Ile 1 5 10 15 Tyr < 210 > 60 < 211 > 12 < 212 > PRT < 213 > Artificial sequence < 220 > < 223 > Synthetic Polypeptide < 400 > 60 Ser Phe Glu Asp Phe Trp Lys Gly Glu Asp Leu Ser 1 5 10 < 210 > 61 < 211 > 15 < 212 > PRT < 213 > Artificial sequence < 220 > < 223 > Synthetic Polypeptide < 400 > 61 Gly Gly Gly Gly Ser Gly Gly Gly Gly Ser Gly Gly Gly Gly Ser 1 5 10 15 < 210 > 62 < 211 > 4 < 212 > PRT < 213 > Artificial sequence < 220 > < 223 > Synthetic Polypeptide < 400 > 62 Cys Pro Pro Cys 1