SEQUENCE LISTING < 110 > Vaccinex , Inc . ZAUDERER , Maurice < 120 > EARLY DETECTION OF GLIAL CELL ACTIVATION IN NEURODEGENERATIVE OR NEUROINFLAMMATORY DISEASES < 130 > 58008 - 172847 < 150 > 62 / 461 , 945 < 151 > 2017 - 02 - 22 < 160 > 10 < 170 > PatentIn version 3 . 5 < 210 > 1 < 211 > 118 < 212 > PRT < 213 > Artificial Sequence < 220 > < 223 > VX 15 / 2503 VH < 400 > 1 Gln Val Gln Leu Val Gln Ser Gly Ala Glu Val Lys Lys Pro Gly Ser 1 5 10 15 Ser Val Lys Val Ser Cys Lys Ala Ser Gly Tyr Ser Phe Ser Asp Tyr 20 25 30 Tyr Met His Trp Val Arg Gln Ala Pro Gly Gln Gly Leu Glu Trp Met 35 40 45 Gly Gln Ile Asn Pro Thr Thr Gly Gly Ala Ser Tyr Asn Gln Lys Phe 50 55 60 Lys Gly Lys Ala Thr Ile Thr Val Asp Lys Ser Thr Ser Thr Ala Tyr 65 70 75 80 Met Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys 85 90 95 Ala Arg Tyr Tyr Tyr Gly Arg His Phe Asp Val Trp Gly Gln Gly Thr 100 105 110 Thr Val Thr Val Ser Ser 115 < 210 > 2 < 211 > 10 < 212 > PRT < 213 > Artificial Sequence < 220 > < 223 > VX 15 / 2503 HCDR 1 < 400 > 2 Gly Tyr Ser Phe Ser Asp Tyr Tyr Met His 1 5 10 < 210 > 3 < 211 > 17 < 212 > PRT < 213 > Artificial Sequence < 220 > < 223 > VX 15 / 2503 HCDR 2 < 400 > 3 Gln Ile Asn Pro Thr Thr Gly Gly Ala Ser Tyr Asn Gln Lys Phe Lys 1 5 10 15 Gly < 210 > 4 < 211 > 9 < 212 > PRT < 213 > Artificial Sequence < 220 > < 223 > VX 15 / 2503 HCDR 3 < 400 > 4 Tyr Tyr Tyr Gly Arg His Phe Asp Val 1 5 < 210 > 5 < 211 > 111 < 212 > PRT < 213 > Artificial Sequence < 220 > < 223 > VX 15 / 2503 VL < 400 > 5 Asp Ile Val Met Thr Gln Ser Pro Asp Ser Leu Ala Val Ser Leu Gly 1 5 10 15 Glu Arg Ala Thr Ile Asn Cys Lys Ala Ser Gln Ser Val Asp Tyr Asp 20 25 30 Gly Asp Ser Tyr Met Asn Trp Tyr Gln Gln Lys Pro Gly Gln Pro Pro 35 40 45 Lys Leu Leu Ile Tyr Ala Ala Ser Asn Leu Glu Ser Gly Val Pro Asp 50 55 60 Arg Phe Ser Gly Ser Gly Ser Gly Thr Asp Phe Thr Leu Thr Ile Ser 65 70 75 80 Ser Leu Gln Ala Glu Asp Val Ala Val Tyr Tyr Cys Gln Gln Ser Asn 85 90 95 Glu Asp Pro Tyr Thr Phe Gly Gln Gly Thr Lys Leu Glu Ile Lys 100 105 110 < 210 > 6 < 211 > 15 < 212 > PRT < 213 > Artificial Sequence < 220 > < 223 > VX 15 / 2503 LCDR 1 < 400 > 6 Lys Ala Ser Gln Ser Val Asp Tyr Asp Gly Asp Ser Tyr Met Asn 1 5 10 15 < 210 > 7 < 211 > 7 < 212 > PRT < 213 > Artificial Sequence < 220 > < 223 > VX 15 / 2503 LCDR 2 < 400 > 7 Ala Ala Ser Asn Leu Glu Ser 1 5 < 210 > 8 < 211 > 9 < 212 > PRT < 213 > Artificial Sequence < 220 > < 223 > VX 15 / 2503 LCDR 3 < 400 > 8 Gln Gln Ser Asn Glu Asp Pro Tyr Thr 1 5 < 210 > 9 < 211 > 118 < 212 > PRT < 213 > Artificial Sequence < 220 > < 223 > Mab 67 VH < 400 > 9 Gln Val Gln Leu Gln Gln Ser Gly Pro Glu Leu Val Lys Pro Gly Ala 1 5 10 15 Ser Val Lys Ile Ser Cys Lys Ala Ser Gly Tyr Ser Phe Ser Asp Tyr 20 25 30 Tyr Met His Trp Val Lys Gln Ser Pro Glu Asn Ser Leu Glu Trp Ile 35 40 45 Gly Gln Ile Asn Pro Thr Thr Gly Gly Ala Ser Tyr Asn Gln Lys Phe 50 55 60 Lys Gly Lys Ala Thr Leu Thr Val Asp Lys Ser Ser Ser Thr Ala Tyr 65 70 75 80 Met Gln Leu Lys Ser Leu Thr Ser Glu Glu Ser Ala Val Tyr Tyr Cys 85 90 95 Thr Arg Tyr Tyr Tyr Gly Arg His Phe Asp Val Trp Gly Gln Gly Thr 100 105 110 Thr Val Thr Val Ser Ser 115 < 210 > 10 < 211 > 111 < 212 > PRT < 213 > Artificial Sequence < 220 > < 223 > Mab 67 VL < 400 > 10 Asp Ile Val Met Thr Gln Ser Pro Ala Ser Leu Ala Val Ser Leu Gly 1 5 10 15 Gln Arg Ala Thr Ile Ser Cys Lys Ala Ser Gln Ser Val Asp Tyr Asp 20 25 30 Gly Asp Ser Tyr Met Asn Trp Tyr Gln Gln Lys Pro Gly Gln Pro Pro 35 40 45 Lys Leu Leu Ile Tyr Ala Ala Ser Asn Leu Glu Ser Gly Ile Pro Ala 50 55 60 Arg Phe Ser Gly Ser Gly Ser Gly Thr Asp Phe Thr Leu Asn Ile His 65 70 75 80 Pro Val Glu Glu Glu Asp Ala Ala Thr Tyr Tyr Cys Gln Gln Ser Asn 85 90 95 Glu Asp Pro Tyr Thr Phe Gly Gly Gly Thr Lys Leu Glu Ile Lys 100 105 110