1 H NMR ( CDCl 3 ) δ 8 . 62 ( 1 H , ddd , J = 4 . 9 , 1 . 8 , 1 . 2 Hz ) , 7 . 51 ( 1 H , ddd , J = 7 . 9 , 1 . 8 , 1 . 2 Hz ) , 7 . 41 ( 1 H , dd , J = 8 . 6 , 6 . 1 Hz ) , 7 . 24 ( 1 H , dd , J = 7 . 9 , 4 . 9 Hz ) , 7 . 19 ( 1 H , dd , J = 7 . 9 , 3 . 1 Hz ) , 7 . 19 ( 1 H , br ) , 7 . 00 ( 1 H , ddd , J = 8 . 6 , 7 . 9 , 3 . 1 Hz ) , 4 . 64 ( 1 H , dd , J = 14 . 7 , 6 . 1 Hz ) , 4 . 58 ( 1 H , dd , J = 14 . 7 , 6 . 1 Hz ) , 3 . 73 ( 2 H , t , J = 6 . 1 Hz ) , 3 . 71 ( 1 H , br ) , 3 . 23 ( 1 H , d , J = 13 . 4 Hz ) , 3 . 18 ( 1 H , d , J = 13 . 4 Hz ) , 2 . 82 - 2 . 63 ( 3 H , m ) , 2 . 45 ( 1 H , m ) , 2 . 31 ( 1 H , m ) , 2 . 17 ( 1 H , m ) , 1 . 69 ( 1 H , br ) .