As a web developer , i believe that templating should be separate from logic and all js for that matter I fucking hate shopify . <| sep |> Well you are right , you are a massive twat <| sep |> Can we please don ' t . Or start with removing the Nulls . <| sep |> David E . Nichols himself stated that hydrolysis in vivo would likely be possible and that 1 PLSD would not be able to bind to the receptors responsible for psychedelic effects . I am sure that the 1 propionyl would also hydrolyze off of an indole , but I don ' t know whether in vivo conditions would work . In a chemistry lab , you can get off an Nbenzoyl , so an Npropionyl will probably come off too . But in the body ? I don ' t know the answer to that . The compound would not be active as the Npropionyl however . The way that LSD docks into the 5 HT 2 A receptor , the indole NH hydrogen bonds to serine 5 . 46 . With the propionyl , it won ' t fit into the receptor . And LSD was detected via LCMS after 1 PLSD was incubated the human serum . LSD wiki has a few good sources and I ' m too busy to find others right now , but all evidence points to the fact that 1 PLSD is barely active on its own before it gets hydrolyzed into LSD