Well now I ' m sad <| sep |> Took it off for the photo <| sep |> Could you elaborate on why Harpoon 385 is incorrect ? I ' ve seen some trans women advocate avoiding antiandrogens in lieu of getting their E 2 levels to 400600 pgmL , believing that this is enough to reduce T levels to cis female norms on its own . They believe that Spiro is very bad for you and should not be taken , and that E 2 levels in that 400600 pgmL range are safe because the E 2 they ' re taking is bioidentical , taken by patch or injection , and that if it means going off of AAs , substantially increasing E 2 levels is worth the risk . I don ' t have enough knowledge on the subject to know with any certainty if they ' re right or wrong I just know that the guidelines all point to 200 pgmL E 2 and 86 or so ngdL T , but I ' m sure you do .