화합물 187 - E 1 LC / MS ESI 521 . 2 ( M + H ) +. 1 H NMR ( 500 MHz , MeOD ) δ 7 . 54 ( d , J = 7 . 6 Hz , 1 H ) , 7 . 40 ( t , J = 7 . 3 Hz , 1 H ) , 7 . 15 ( dd , J = 7 . 3 , 4 . 3 Hz , 1 H ) , 7 . 10 ( d , J = 8 . 4 Hz , 1 H ) , 7 . 00 ( t , J = 7 . 5 Hz , 1 H ) , 6 . 40 ( dd , J = 7 . 3 , 2 . 6 Hz , 1 H ) , 5 . 03 ( s , 1 H ) , 4 . 81 ? 4 . 72 ( m , 1 H ) , 3 . 88 ? 3 . 59 ( m , 3 H ) , 3 . 55 ? 3 . 37 ( m , 4 H ) , 3 . 30 ? 3 . 22 ( m , 2 H ) , 3 . 15 ? 2 . 95 ( m , 1 H ) , 2 . 71 ( t , J = 6 . 2 Hz , 2 H ) , 2 . 62 ? 2 . 53 ( m , 2 H ) , 2 . 40 ( td , J = 15 . 8 , 8 . 1 Hz , 1 H ) , 2 . 30 ? 2 . 06 ( m , 3 H ) , 1 . 92 ? 1 . 85 ( m , 2 H ) , 1 . 75 ( dd , J = 14 . 9 , 7 . 4 Hz , 2 H ) , 1 . 69 ? 1 . 51 ( m , 1 H ) , 1 . 44 ( dd , J = 10 . 7 , 6 . 0 Hz , 6 H ) . 키 랄 SFC F ( 40 % EtOH ) : ee 95 %, Rt = 7 . 8 분 .