< 110 > KOREA FOOD RESEARCH INSTITUTE < 120 > Composition for Inhibiting PCSK 9 Gene Expression or Increasing Amount of Low Density Lipoprotein Receptor Comprising Butein or Isoeugenol < 130 > PN 170187 < 160 > 12 < 170 > KopatentIn 2 . 0 < 210 > 1 < 211 > 19 < 212 > DNA < 213 > Artificial Sequence < 220 > < 223 > PCSK 9 Forward Primer < 400 > 1 ggcaggttgg cagctgttt 19 < 210 > 2 < 211 > 18 < 212 > DNA < 213 > Artificial Sequence < 220 > < 223 > PCSK 9 Reverse Primer < 400 > 2 cgtgtaggcc ccgagtgt 18 < 210 > 3 < 211 > 20 < 212 > DNA < 213 > Artificial Sequence < 220 > < 223 > LDLR Forward Primer < 400 > 3 aggagacgtg cttgtctgtc 20 < 210 > 4 < 211 > 18 < 212 > DNA < 213 > Artificial Sequence < 220 > < 223 > LDLR Reverse Primer < 400 > 4 ctgagccgtt gtcgcagt 18 < 210 > 5 < 211 > 21 < 212 > DNA < 213 > Artificial Sequence < 220 > < 223 > SREBP 2 Forward Primer < 400 > 5 cggtaatgat cacgccaaca t 21 < 210 > 6 < 211 > 23 < 212 > DNA < 213 > Artificial Sequence < 220 > < 223 > SREBP 2 Reverse Primer < 400 > 6 tggtatatca aaggctgctg gat 23 < 210 > 7 < 211 > 23 < 212 > DNA < 213 > Artificial Sequence < 220 > < 223 > HMGCR Forward Primer < 400 > 7 caaggagcat gcaaagataa tcc 23 < 210 > 8 < 211 > 19 < 212 > DNA < 213 > Artificial Sequence < 220 > < 223 > HMGCR Reverse Primer < 400 > 8 gccattacgg tcccacaca 19 < 210 > 9 < 211 > 20 < 212 > DNA < 213 > Artificial Sequence < 220 > < 223 > HNF 1 alpha Forward Primer < 400 > 9 tggcgcagca gttcacccat 20 < 210 > 10 < 211 > 20 < 212 > DNA < 213 > Artificial Sequence < 220 > < 223 > HNF 1 alpha Reverse Primer < 400 > 10 tgaaacggtt cctccgcccc 20 < 210 > 11 < 211 > 21 < 212 > DNA < 213 > Artificial Sequence < 220 > < 223 > GAPDH Forward Primer < 400 > 11 atgttcgtca tgggtgtgaa c 21 < 210 > 12 < 211 > 21 < 212 > DNA < 213 > Artificial Sequence < 220 > < 223 > GAPDH Reverse Primer < 400 > 12 gcatggactg tggtcatgag t 21