IIRC autophagy can only happen in a lowinsulin , protein deprived state . So it wouldn ' t happen eating a keto diet because even though insulin is low , you are still getting dietary protein which also raises insulin . I ' m doing a science experiment now where I only eat one largish , lowish carb meal after lifting every other day . A typical meal would be something like 300 g fatty meat or 250 g lean meat fatty food like nuts or avocado with a bunch of lowishcarb vegetables . For example last night I had 300 g of pork shoulder cooked with about half a cabbage and some onion and apple . That was about 50 grams of protein , 20 g carbohydrates , and probably 6070 g of fat from the pork and cooking oil . I feel good and if it turns out to be sustainable I should be able to lose quite a lot of weight fairly fast without any question of muscle loss .