화합물 12 - E 1 LC / MS A : 98 % 순도 , UV = 214 nm , Rt = 1 . 61 분 , ESI 423 . 5 ( M + H ) +. 1 H - NMR ( 400 MHz , MeOD ) δ 7 . 61 ? 7 . 50 ( m , 2 H ) , 7 . 48 ? 7 . 38 ( m , 3 H ) , 7 . 14 ( d , J = 7 . 3 Hz , 1 H ) , 6 . 36 ( d , J = 7 . 3 Hz , 1 H ) , 4 . 46 ( s , 1 H ) , 3 . 57 ( s , 1 H ) , 3 . 46 ( t , J = 6 . 2 Hz , 2 H ) , 3 . 41 ? 3 . 35 ( m , 2 H ) , 3 . 14 ( s , 1 H ) , 2 . 85 ( s , 1 H ) , 2 . 71 ( t , J = 6 . 2 Hz , 2 H ) , 2 . 53 ( t , J = 7 . 5 Hz , 2 H ) , 2 . 19 ? 1 . 79 ( m , 7 H ) , 1 . 56 - 1 . 63 ( m , 5 H ) . 키 랄 SFC A ( 45 % MeOH ) : ee 96 . 2 %, Rt = 1 . 88 분 .