When you say ' don ' t have to be far into the ketosis spectrum ', what are you referring to exactly ? I thought 20 g ~ carbs was the entry point to the ketosis spectrum for most ? I mean if i ' m eating a low carb diet 75100 g throughout the day i ' ll be in ketosis over night , is there much research into the benefits of phasing in and out of ketosis but maintaining fat adaption but not working on ketones 247 ? <| sep |> I ' d say yes . I did six hours there a week or so back starting at the eye and then the needle . With the current xp and stardust bonus it ' s well worth the time and I really wish I could do it this weekend . The Xmas fair by the eye is pretty cool too , especially the beer stall . <| sep |> An LCMS time course would put this to bed , but I agree with the commenters that caffeine isn ' t likely to decompose in water after surviving the roasting process E I love this post because right now I ' m trying to figure out what ' s happening with this nonenzymatic ' metabolite ' forming in slightly high pH water from a 40 mer peptide loaded with reactive sidechains and now I ' m considering if my precious caffeine , which is a thermodynamic sink of a molecule , might also be doing weird chemistry in water . calgon take me away !