Okay , I did tally up a total of 277 from Fates Collide and found another 57 from Generations as well if you change your mind . For the original 417 I mentioned , 6 cents each would be $ 25 . 02 , it looks like it will cost me about $ 6 . 80 to ship it , so I think an even $ 25 would be fine to cover it all . <| sep |> no need to be mean about it tho cmon <| sep |> Well do you want challenge or fun ? Now that you have access to SheolCathedral I would recommend unlocking the ChestDark Room you already have the dark room , now go best issac ! With as many characters as you can . Or you can start doing some of Isaac ' s Bucket list and do some challenges , they all unlock something useful one way or another , do the easy challenges first . You could also do what I do and alternate , when playing the game gets boring , do some challenges , and when the challenges get boring , play as some characters That ' s stuff I dodid anyway , but I don ' t have afterbirth yet so we , I do know greed mode is a entirely different beast though . good luck anyways ! Edit Dammit autocorrect , I don ' t even know what a damn Buckley list is .