남자 중학생 에서 비만 과 high sensitiviy C - reactive protein 의 관계 
 Jae - Ho Jeong ( Jeong JH ) , Jae - Woo Lim ( Lim JW ) , Eun - Jeong Cheon ( Cheon EJ ) , Kyong - Og Ko ( Ko KO ) , Young - Hyuk Lee ( Lee YH ) 
 Jae - Ho Jeong , Jae - Woo Lim , Eun - Jeong Cheon , Kyong - Og Ko , Young - Hyuk Lee 
 Department of Pediatrics , College of Medicine , Konyang University , Daejeon , Korea 
 정재호 , 임재우 , 천은정 , 고경옥 , 이영혁 
 건양 대학교 의과 대학 소아 과학 교실 
 Correspondence : Eun - Jeong Cheon , 
 Email : kcm 1000 @ kyuh . co . kr 
 : High - Sensitivity C - reactive protein ( hs - CRP ) has been recognized as a very useful and sensitive predictor of the future risk of myocardial infarction . But the clinical significance of hs - CRP in children remains uncertain . To confirm the existence of obesity - induced vascular inflammation and the association between metabolic syndromes and elevation of CRP in children , we investigated the relationship among CRP , obesity , blood pressure ( BP ) , and serum lipids in schoolboys . 
 : Twenty - eight obese ( BMI 29 . 61 ¡¾ 3 . 29 kg / m 2 ) and 93 non - obese ( BMI 18 . 99 ¡¾ 2 . 21 kg / m 2 ) boys aged 14 years were examined . Serum CRP levels was measured by the high sensitive latex turbidimetric immunoassay and subjects with CRP levels below 0 . 3 mg / dL were adopted to avoid the influence of acute infection . 
 : Obese children had significantly higher hs - CRP levels than their non - obese group ( 0 . 104 ¡¾ 0 . 075 vs . 0 . 054 ¡¾ 0 . 005 mg / dL ) . In the obese group , BMI , systolic blood pressure , diastolic blood pressure , apolipoprotein B , atherogenic index , and triglyceride were significantly higher than in non - obese . The BMI , diastolic blood pressure , apolipoprotein E , atherognic index , and triglyceride showed positive correlation with log CRP by simple regression . Multiple regression analysis indicated that BMI and apolipoprotein E were strongly related to CRP . 
 : This study revealed that obese children tended to have higher levels of serum hs - CRP , BP elevation and dyslipidemia than the control group and that BMI and apolipoprotein E were strongly related to CRP . These results indicate that obesity related metabolic syndrome can be developed in children . 
 Key Words : Obesity , hs - CRP , Metabolic syndrome