화합물 198 - E 2 LC / MS ESI 424 . 1 ( M + H ) +. 1 H NMR ( 500 MHz , MeOD ) δ 7 . 44 ( d , J = 7 . 8 Hz , 1 H ) , 7 . 34 ? 7 . 28 ( m , 2 H ) , 7 . 25 ? 7 . 16 ( m , 2 H ) , 6 . 39 ( d , J = 7 . 3 Hz , 1 H ) , 4 . 99 ( s , 1 H ) , 4 . 28 ( d , J = 5 . 2 Hz , 2 H ) , 3 . 95 ( s , 1 H ) , 3 . 76 ( d , J = 4 . 8 Hz , 1 H ) , 3 . 56 ( d , J = 9 . 5 Hz , 1 H ) , 3 . 45 ? 3 . 40 ( m , 4 H ) , 2 . 96 ? 2 . 90 ( m , 2 H ) , 2 . 71 ( t , J = 6 . 2 Hz , 2 H ) , 2 . 56 ( t , J = 7 . 6 Hz , 2 H ) , 1 . 91 ? 1 . 83 ( m , 2 H ) ) , 1 . 75 ? 1 . 65 ( m , 2 H ) , 1 . 64 ? 1 . 54 ( m , 2 H ) , 1 . 34 ( t , J = 7 . 6 Hz , 3 H ) . 키 랄 HPLC K ( 50 % EtOH ) : ee 100 %, Rt = 7 . 56 분 .