10 . Richon , V . M . , Emiliani , S . , Verdin , E . , Webb , Y . , Breslow , R . , Rifkind , R . A . and Marks , P . A . ( 1998 ) A class of hybrid polar inducers of transformed cell differentiation inhibits histone deacetylases . Proc Natl Acad Sci U S A , 95 , 3003 - 7 .