1 H NMR ( 400 MHz , CDCl 3 ) δ 12 . 86 ( br , 1 H ) , 8 . 48 ( br , 1 H ) , 7 . 10 ( d , J = 8 . 8 Hz , 1 H ) , 6 . 94 ( d , J = 2 . 4 Hz , 1 H ) , 6 . 91 ( dd , J = 8 . 4 , 2 . 4 Hz , 1 H ) , 5 . 74 ( s , 2 H ) , 3 . 71 ( br , 1 H ) , 3 . 23 - 3 . 14 ( m , 2 H ) , 3 . 04 ( br d , J = 19 . 2 Hz , 1 H ) , 2 . 78 - 2 . 76 ( m , 1 H ) , 2 . 34 ( d , J = 14 . 0 Hz , 1 H ) , 2 . 23 ( d , J = 7 . 2 Hz , 2 H ) , 2 . 13 - 2 . 05 ( m , 1 H ) , 2 . 01 - 2 . 00 ( m , 1 H ) , 1 . 92 - 1 . 85 ( m , 1 H ) , 1 . 69 - 1 . 34 ( m , 6 H ) , 1 . 29 - 1 . 23 ( m , 1 H ) , 1 . 10 - 0 . 97 ( m , 1 H ) , 0 . 92 ( d , J = 6 . 8 Hz , 6 H ) .