화합물 188 - E 1 LC / MS ESI 507 . 2 ( M + H ) +. 1 H NMR ( 500 MHz , MeOD ) δ 7 . 33 ( dd , J = 16 . 8 , 7 . 8 Hz , 2 H ) , 7 . 07 ( d , J = 7 . 3 Hz , 1 H ) , 7 . 03 ( d , J = 8 . 4 Hz , 1 H ) , 6 . 92 ( t , J = 7 . 5 Hz , 1 H ) , 6 . 32 ( dd , J = 7 . 3 , 1 . 8 Hz , 1 H ) , 5 . 08 ( s , 1 H ) , 4 . 69 ( dt , J = 12 . 1 , 6 . 0 Hz , 1 H ) , 4 . 40 ? 4 . 06 ( m , 3 H ) , 3 . 86 ( s , 1 H ) , 3 . 76 ? 3 . 69 ( m , 1 H ) , 3 . 58 ? 3 . 40 ( m , 2 H ) , 3 . 31 ( dt , J = 12 . 8 , 4 . 8 Hz , 3 H ) , 2 . 97 ? 2 . 89 ( m , 1 H ) , 2 . 64 ( t , J = 5 . 7 Hz , 2 H ) , 2 . 52 ? 2 . 46 ( m , 2 H ) , 2 . 18 ? 1 . 99 ( m , 2 H ) , 1 . 85 ? 1 . 78 ( m , 2 H ) , 1 . 70 ? 1 . 64 ( m , 2 H ) , 1 . 61 ? 1 . 44 ( m , 1 H ) , 1 . 40 ? 1 . 34 ( m , 6 H ) . 키 랄 SFC F ( 40 % EtOH ) : ee 100 %, Rt = 9 . 14 분