이 측정 은 , [ OECD GUIDELINE FOR TESTING OF CHEMICALS , " 112 ( 1981 ) "" Dissociation Constants in Water ""] 또는 [ A . Albert ", E . P . Serjeant , Determination of Ionization Constants , Chapter 2 : Determination of ionization constants by potentiometric titration using a glass electrode , Chapman and Hall , London ( 1984 ) ] 에 따라 이뤄졌 다 .