화합물 187 - E 2 LC / MS ESI 521 . 2 ( M + H ) +. 1 H NMR ( 500 MHz , MeOD ) δ 7 . 43 ( d , J = 7 . 5 Hz , 1 H ) , 7 . 35 ? 7 . 30 ( m , 1 H ) , 7 . 09 ? 7 . 05 ( m , 1 H ) , 7 . 01 ( d , J = 8 . 3 Hz , 1 H ) , 6 . 92 ( t , J = 7 . 5 Hz , 1 H ) , 6 . 32 ( dd , J = 7 . 3 , 1 . 5 Hz , 1 H ) , 4 . 99 ( s , 1 H ) , 4 . 68 ( dt , J = 12 . 1 , 6 . 0 Hz , 1 H ) , 3 . 67 ? 3 . 51 ( m , 3 H ) , 3 . 46 ? 3 . 29 ( m , 5 H ) , 3 . 21 ? 2 . 86 ( m , 2 H ) , 2 . 64 ( t , J = 6 . 2 Hz , 2 H ) , 2 . 55 ? 2 . 46 ( m , 2 H ) , 2 . 32 ( s , 1 H ) , 2 . 23 ? 1 . 98 ( m , 3 H ) , 1 . 84 ? 1 . 77 ( m , 2 H ) , 1 . 68 ( dd , J = 14 . 9 , 7 . 3 Hz , 2 H ) , 1 . 63 ? 1 . 45 ( m , 1 H ) , 1 . 35 ( dd , J = 12 . 9 , 6 . 0 Hz , 6 H ) . 키 랄 SFC F ( 40 % EtOH ) : ee 100 %, Rt = 9 . 6 분 .