while 117 probably isn ' t high enough to cause toxicity , it may cause issues with calcium . It won ' t , when you add K 2 MK 7 . You should add it anyway . That , I ' ve never heard before , wouldn ' t be surprised , but E 2 is vastly more important for brain , bone , libido , and erectile health . If it comes to sex , high E 2 will make your dick limp . Low on the other hand will make you hard to come and cause tragic orgasms , if you ever get one . I often follow bodybuilding sitesforums and sometimes when some newbies kill their E 2 completely their liver enzymes and blood work are so bad , they would count for a liver transplant . Your whole body will work with super low estrogens , liver won ' t . What made you say my E 2 was very low ? Your testosterone being at a high , or even above range , plus HCG administration . Most people I guess would have it much more elevated . Well with respect to HCG , it will depend on the person ' s level of intratesticular aromatase activity , not just peripheral aromatase . You ' re right