I ' ve been using the Osprey 46 ozone 46 travelpack . I ' ve had it for about a year , and it holds holds my 17 r 3 , 3 days worth of clothes , a bathroom bag , wacom tablet , a big bundle of wires , AC adapters , plus a ton of over misc stuff . I ' m 100 % sure it would fit your devices even if they have protective sleeves . It ' s a tough pack , but an important note is the 17 r 3 doesn ' t actually fit in the laptop compartment in the back of the backpack so the Everki might win that battle , not sure if a 17 . 3 will fit in the Everki sleeve . The Osprey sleeve is designed for a 15 laptop , so I just use that compartment for my wacom , drawing pads , and books . I have to put the Alienware in it ' s own basic sleeve in the main compartment of the Osprey bag . After a little research , I ' m seeing that this Osprey model is REI exclusive , but REI has an insanely good return policy . Anyways , this pack is great for travel , but like the Everki , it ' s freaking huge . I ' ve also had my eyes on these guys bags . I called Timbuk 2 , and they said I ' d need a classic Large commuter or messenger for the alienware 17 r 4 , which they calculated to be a diagonal of 22 . Might pick one up , not sure yet . Good luck on the quest , would you mind please posting your impression of the 17 r 4 once you get it ? Mine ' s arriving on Tuesday and I ' ll do the same .