Chloralose

Chloralose (also known as α-chloralose) is an avicide, and a rodenticide used to kill mice in temperatures below 15 °C.  It is also widely used in neuroscience and veterinary medicine as an anesthetic and sedative.

Chemically, it is a chlorinated acetal derivative of glucose.

It is listed in Annex I of Directive 67/548/EEC with the classification Harmful (Xn)

Chloralose exerts barbiturate-like actions on synaptic transmission in the brain, including potent effects at inhibitory γ-aminobutyric acid type A (GABAA) receptors.  A structural isomer of chloralose, β-chloralose (also called parachloralose in older literature), is inactive as a GABAA modulator and also as a general anesthetic.

References

Category:Acetals
Category:Polyols
Category:Monosaccharide derivatives
Category:Rodenticides
Category:Avicides
Category:GABAA receptor positive allosteric modulators
Category:Sedatives
Category:General anesthetics
Category:Trichloromethyl compounds