Bisphosphoglycerate phosphatase

In enzymology, a bisphosphoglycerate phosphatase () is an enzyme that catalyzes the chemical reaction

2,3-bisphospho-D-glycerate + H2O  3-phospho-D-glycerate + phosphate

Thus, the two substrates of this enzyme are 2,3-bisphospho-D-glycerate and H2O, whereas its two products are 3-phospho-D-glycerate and phosphate.

This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric monoester bonds.  The systematic name of this enzyme class is 2,3-bisphospho-D-glycerate 2-phosphohydrolase. Other names in common use include 2,3-diphosphoglycerate phosphatase, diphosphoglycerate phosphatase, 2,3-diphosphoglyceric acid phosphatase, 2,3-bisphosphoglycerate phosphatase, and glycerate-2,3-diphosphate phosphatase.  This enzyme participates in glycolysis/gluconeogenesis.

Structural studies

As of late 2007, 7 structures have been solved for this class of enzymes, with PDB accession codes , , , , , , and .

References

 
 

Category:EC 3.1.3
Category:Enzymes of known structure