FORM: UCSF-Harvard  No. __________ 
NATIONAL INSTITUTE OF GENETICS 
Research Organization of Information and Systems 
            1111 Yata, Mishima, Shizuoka 411-8540, Japan URL: http://www.nig.ac.jp/ 
MATERIAL TRANSFER AGREEMENT 
 (Distribution for academic use only) 
    The National Institute of Genetics (NIG) is engaged in collecting, maintaining, storing, multiplying and distributing the biological resources, in order to contribute to the research community for the development of the research and utilization in the field of life sciences.     In response to the RECIPIENT’s request for the material under the National BioResource Project (NBRP), NIG asks that the RECIPIENT agrees to the following before the RECIPIENT receives the material. The RECIPIENT, the RECIPIENT SCIENTIST, the RECIPIETNT Principal Investigator (RECIPIENT PI) and NIG must sign two copies of this agreement. NIG will then send the material to the RECIPIENT.  I. Definitions: 
ORIGINAL MATERIAL: The material provided by NIG to the RECIPIENT MATERIAL: ORIGINAL MATERIAL and its PROGENY.  PROGENY: Unmodified descendant from ORIGINAL MATERIAL. MODIFICATIONS: Substances created by the RECIPIENT which contain/incorporate the MATERIAL.  RESEARCH PROJECT: (described with specificity as follows)  __________________________________________________________________________ 
    Name of RESEARCH PROJECT (Academic Research only)    
II. Terms and Conditions:  
1. ORIGINAL MATERIAL is derived from the MATERIAL deposited by the University 
of California San Francisco and the Harvard Medical School (DEPOSITORS). The DEPOSITORS retain ownership of the MATERIAL, including any MATERIAL contained or incorporated in MODIFICATIONS. 
2. The RECIPIENT agrees that the MATERIAL:    (a)  is to be used solely for teaching and academic research purposes in non-profit 
organization. 
  (b) shall not be used commercially or for research that is subject to consulting or 
licensing obligations to another entity or commercial organization whether or not such obligations presently exist or are entered into in the future unless prior written permission is obtained from both of the DEPOSITORS and NIG. 
  (c) will not be used in human subjects, in clinical trials, or for diagnostic purposes 
involving human subjects.  
  (d) is to be used only at the RECIPIENT organization and only in the RECIPIENT PI 
laboratory under the direction of the RECIPIENT PI or others working under his/her direct supervision; and  
  (e) will not be further distributed to others. 3. The RECIPIENT shall inform the publication and send the copy of the article to NIG 
Authorized Official. The RECIPIENT agrees to acknowledge the DEPOSITORS and the National BIO-Resource Project (NBRP) in any publications reporting use of it.  
4. The MATERIAL will be used by the RECIPIENT SCIENTIST and RECIPIENT PI 
Insert applicable information 
Please briefly describe how the material will 
be used in your research. This will assist us 
confirming that the agreement is consistent 
with your research plans. 
FORM: UCSF-Harvard  No. __________ 
and by individuals supervised by the RECIPIENT PI's direction in his/her laboratory for not-for-profit research only and solely in connection with the RESEARCH PROJECT. 
5. The RECIPIENT may distribute MODIFICATIONS to non-profit organization for 
academic research purpose only, and should not provide MODIFICATIONS for commercial purposes without prior written consent of NIG and DEPOSITORS. 
6. Prior to filing an application for a patent, or intellectual property or other rights 
based on the results of research using the MATERIAL, RECIPIENTS shall acquire the consent from the DEPOSITORS for such application. Inventorship shall be determined in accordance with patent law (if patentable) or by mutual agreement between the parties (if not patentable), taking into account the role and contributions of individuals involved in the research. In the case of a joint invention, the DEPOSITORS and the RECIPIENT agree to negotiate a joint application agreement, which shall provide, inter alia, for the sharing of patent costs, income, and invention management responsibilities. 
7. Any MATERIAL delivered pursuant to this agreement is understood to be 
experimental in nature and may have hazardous properties. NIG MAKES NO REPRESENTATIONS AND EXTENDS NO WARRANTIES OF ANY KIND, EITHER EXPRESSED OR IMPLIED. THERE ARE NO EXPRESS OR IMPLIED WARRANTIES OF MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE, OR THAT THE USE OF THE MATERIAL WILL NOT INFRINGE ANY PATENT, COPYRIGHT, TRADEMARK, OR OTHER PROPRIETARY RIGHTS.  
8. Except to the extent prohibited by law, the RECIPIENT assumes all liability for 
damages, which may arise from its use, storage or disposal of the MATERIAL. NIG will not be liable to the RECIPIENT for any loss, claim or demand made by the RECIPIENT, or made against the RECIPIENT by any other party, due to or arising from the use of the MATERIAL by the RECIPIENT, except to the extent permitted by law when caused by the gross negligence or willful misconduct of NIG and/or the DEPOSITORS.  
9. The RECIPIENT agrees to use the MATERIAL in compliance with all applicable 
statutes and regulations. 
Note: 
This Agreement shall be effective when signed by all Parties, and its effective date is the 
latest of the dates set out blow. 
FORM: UCSF-Harvard  No. __________ 
III. NIG INFORMATION and SIGNATURES  
NIG Scientist Hironori Niki, Ph.D., Professor in Microbial Physiology 
Laboratory, National Institute of Genetics 
NIG Authorized Official: Mutsuaki Suzuki, Ph.D., Director of NIG INNOVATION, 
National Institute of Genetics 
E-mail:  chizai@nig.ac.jp 
Address 1111 Yata, Mishima, Shizuoka, 411-8540 Japan 
      Signature of NIG’s Authorized Official                                    Date 
 IV. RECIPIENT INFORMATION and SIGNATURES  
RECIPIENT SCIENTIST 
Name, Title, and email address 
Name:  
Title:  
E-mail:                    
RECIPIENT PI 
(Principal Investigator) 
Name, Title, and email address 
Name:  
Title:  
E-mail:                    
Laboratory 
Name and Address 
Lab. Name: 
Address:  
Authorized Official 
Name, Title, and email address 
Name:  
Title:  
E-mail:                   
RECIPIENT Organization  
Name and Address: 
Org. Name: 
Address:  
                                                   RECIPENT should be academic institution 
                                                                 
       Signature of RECIPIENT SCIENTIST                                Date 
      
                                                            
       Signature of RECIPIENT PI                                         Date 
      Signature of RECIPIENT Organization’s Authorized Official              Date 
Print full name,job title,and email address of 
Recipient Scientist 
Print full name,job title,and email address of 
Principal Investigator
Print Laborator name and address
Print full name,job title,and email address of 
Authorized Official 
Print legal name, name of organization, and 
registered address including postcode and country. 
An actual signature is required. 
Date of Signature 
Authorized Official is an individual 
who has signatory approval on behalf 
of university or institute. 
An actual signature is required. 
An actual signature is required. 
An electronic signature is 
NOT acceptable. 